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This paper proposes a local control strategy applied in the soft open point (SOP) to suppress voltage fluctuation when adding a renewable energy source into the system. The mathematic model of the grid connected to SOP is established based on the characteristics of a low-voltage distribution network. Combined with the mathematic model and local voltage information, the local control strategy is proposed to optimize the active and reactive power distribution and consume the minimum apparent power of the converter. The local control strategy can effectively suppress the voltage fluctuation caused by renewable energy access, which was testified by MATLAB/Simulink simulation. In addition, the local control strategy can deduce the communication resource and increase the response speed compared to global optimization. This paper is meaningful for renewable energy source distribution and voltage balance in low-voltage distribution systems. [ABSTRACT FROM AUTHOR]

Resent studies have identified Pygopus as a core component of the β-catenin/T-cell factor (TCF)/lymphoid-enhancing factor 1 (LEF) transcriptional activation complex required for the expression of canonical Wg/Wnt target genes in Drosophila. However, the biochemical involvement of mammalian Pygopus proteins in β-catenin/TCF/LEF gene activation remains controversial. In this study, we perform a series of molecular/biochemical experiments to demonstrate that Pygo2 associates with histone-modifying enzymatic complexes, specifically the MLL2 histone methyltransferase (HMT) and STAGA histone acetyltransferase (HAT) complexes, to facilitate their interaction with β-catenin and to augment Wnt1-induced, TCF/LEF-dependent transcriptional activation in breast cancer cells. We identify a critical domain in Pygo2 encompassing the first 47 amino acids that mediates its HMT/HAT interaction. We further demonstrate the importance of this domain in Pygo2's ability to transcriptionally activate both artificial and endogenous Wnt target genes and to expand breast cancer stem-like cells in culture. This work now links mechanistically Pygo2's role in histone modification to its enhancement of the Wnt-dependent transcriptional program and cancer stem-like cell expansion. [ABSTRACT FROM AUTHOR]