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Beside prosthesis loosening, wear is the mechanical factor that most significantly influences the lifetime of total knee replacements (TKRs), which can only be described by a number of interrelated parameters. The examination of the wear occurring in TKRs is mostly carried out as a combination of experiments and mathematical modeling. The experiment can provide the real magnitude of wear, while the model is intended to mathematically describe the relationship between wear and the wear-inducing parameters. On the one hand, this study focuses on the mathematical description of wear as a natural-technical phenomenon, presenting the most important analytical and numerical models, while also providing an open view on exciting questions that still await answers. [ABSTRACT FROM AUTHOR]

The article focuses on the need to design artificial intelligence (AI) to benefit humanity, highlighting the historical development of Artificial Intelligence (AI), its economic and societal impact, and India's initiatives in promoting AI for inclusive growth. Topics include the importance of ethical considerations, upskilling engineers, and regulatory oversight to ensure the responsible and beneficial integration of AI into various sectors.

This paper presents an identity based multi-proxy multi-signcryption scheme from pairings. In this scheme a proxy signcrypter group could authorized as a proxy agent by the cooperation of all members in the original signcrypter group. Then the proxy signcryption can be generated by the cooperation of all the signcrypters in the authorized proxy signcrypter group on the behalf of the original signcrypter group. As compared to the scheme Liu and Xiao, the proposed scheme provides public verifiability of the signature along with simplified key management. [ABSTRACT FROM AUTHOR]

In order to develop general rules of peptide design with α,β-dehydro-residues, a peptide, Boc-Ala-ΔPhe-ΔPhe-Phe-OCH3, was synthesized. The peptide was crystallized from its solution in an acetone:water mixture (70:30). The crystals belong to orthorhombic space group P212121 with a = 9.403(1) Å, b = 16.871(1) Å, c = 21.638(1) Å, and Z = 4. The peptide adopts a conformation with two overlapping types II′ and III β-turns having dihedral angles, ϕ1 = 53.7(6)∘, ψ1 = −135.9(4)∘, ϕ2 = −59.2(5)∘, ψ2 = −17.9(5)∘, ϕ3 = −68.4(5)∘, ψ3 = −18.8(6)∘. The conformation was further characterized by two intramolecular 4 → 1 hydrogen bonds involving imino nitrogen atoms of ΔPhe3 and Phe4 as donors and carbonyl oxygen atoms of blocking group Boc and Ala1 as acceptors. The packing of the molecules in the unit cell is stabilized by an intermolecular hydrogen bond, N2–H2⋅s O′3 [−x, y+1/2, −z+1/2] = 2.894 Å and van der Waals forces involving aromatic side chains. [ABSTRACT FROM AUTHOR]

A 30-year-old female presented with a painless solitary swelling at right lateral border of tongue of 2-month duration. Fine-needle aspiration cytology was nonconclusive. Excision biopsy was done. Histopathology revealed cysticercosis cellulosae and parasite visualized in the slide with tongue muscles. Lingual cysticercosis is rare and therefore its literature is reviewed and discussed. [ABSTRACT FROM AUTHOR]