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Quench detection for the high-temperature superconducting tape, especially rare-earth barium copper oxide (REBCO) tape, is difficult due to the small normal zone propagation velocity in it. To address this issue, we have proposed a novel quench detectable REBCO tape with a low-temperature superconducting wire used as a quench detector, "REBCO/LTSd tape." In this paper, we numerically and experimentally demonstrated the validity of the tape consisting of the yttrium barium copper oxide (YBCO) tape and the Nb-Ti wire used at 4.2 K under no external field. Results of the numerical simulation showed that sufficiently high voltage of 0.1 V can be detected before the maximum temperature of the YBCO tape reaches 50 K with the Nb-Ti wires having high resistance at normal conducting state. Experimental results also demonstrated that the quench in the YBCO was detected with the 1 V scale voltage by using the pure Nb-Ti wire. [ABSTRACT FROM AUTHOR]

Lines of evidence suggest that hypothalamic neuropeptides have a physiological role in the regulation of food intake in mammals. However, little is known about the age-dependent change of hypothalamic neuropeptides in chicks. In this study, we investigated the age-dependent changes in hypothalamic mRNA levels of neuropeptide Y (NPY, an orexigenic neuropeptide), proopiomelanocortin (POMC, the precursor of anorexigenic neuropeptides), and corticotropin-releasing factor (CRF, a possible mediator in the POMC-induced anorexigenic pathway) in growing broiler chicks. The weights of body and abdominal adipose tissue of chicks were measured at 7, 14, 21, and 28 days of age, and the hypothalamic mRNA levels of NPY, POMC, and CRF were analyzed by real-time PCR. Hypothalamic NPY mRNA levels at 14 and 28 days of age were significantly (P<0.05) lower than that at 7 days of age. Hypothalamic POMC mRNA level at 28 days of age was significantly lower than that at 7 days of age. Hypothalamic CRF mRNA level was not affected throughout the experimental period. Abdominal adipose tissue weight was significantly increased after 14 days of age in chicks. Our findings demonstrated that the expressions of NPY and POMC are dependent on age in boiler chicken hypothalamus. [ABSTRACT FROM AUTHOR]

Abstract  Noncoding microRNAs regulate the expression of various mRNAs. We attempted to clarify the relationship between miR-27a genome polymorphism and chronic gastritis. The study was performed in 179 patients with no evidence of gastric malignancy. The severity of histologic chronic gastritis was classified according to the updated Sydney system. The frequency of miR-27a G allele was 34.6%. Although the frequencies of miR-27a G allele were increased in subjects with peptic ulcer or severe mucosal atrophy, no significant differences were seen. The miR-27a polymorphism showed an interaction with gender in relation to gastric mucosal atrophy (P=.090). In only male subjects, the miR-27a polymorphism was associated with the gastric mucosal atrophy (P=.039) and both atrophy and metaplasia scores in G/G group were significantly higher than those in the other groups. The miR-27a genome region polymorphism may be an important definitive factor to develop the gastric mucosal atrophy in Japanese male subjects. [ABSTRACT FROM AUTHOR]