10 results on '"Sherman, Josiah J. Z."'
Search Results
2. Association of Malnutrition with Surgical and Hospital Outcomes after Spine Surgery for Spinal Metastases: A National Surgical Quality Improvement Program Study of 1613 Patients.
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Elsamadicy, Aladine A., Havlik, John, Reeves, Benjamin C., Sherman, Josiah J. Z., Craft, Samuel, Serrato, Paul, Sayeed, Sumaiya, Koo, Andrew B., Khalid, Syed I., Lo, Sheng-Fu Larry, Shin, John H., Mendel, Ehud, and Sciubba, Daniel M.
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SPINAL surgery ,MALNUTRITION ,LOGISTIC regression analysis ,SURGICAL complications ,METASTASIS ,PATIENT readmissions - Abstract
Background: Malnutrition is a common condition that may exacerbate many medical and surgical pathologies. However, few have studied the impact of malnutrition on surgical outcomes for patients undergoing surgery for metastatic disease of the spine. This study aims to evaluate the impact of malnutrition on perioperative complications and healthcare resource utilization following surgical treatment of spinal metastases. Methods: We conducted a retrospective cohort study using the 2011–2019 American College of Surgeons National Surgical Quality Improvement Program database. Adult patients with spinal metastases who underwent laminectomy, corpectomy, or posterior fusion for extradural spinal metastases were identified using the CPT, ICD-9-CM, and ICD-10-CM codes. The study population was divided into two cohorts: Nourished (preoperative serum albumin values ≥ 3.5 g/dL) and Malnourished (preoperative serum albumin values < 3.5 g/dL). We assessed patient demographics, comorbidities, intraoperative variables, postoperative adverse events (AEs), hospital LOS, discharge disposition, readmission, and reoperation. Multivariate logistic regression analyses were performed to identify the factors associated with a prolonged length of stay (LOS), AEs, non-routine discharge (NRD), and unplanned readmission. Results: Of the 1613 patients identified, 26.0% were Malnourished. Compared to Nourished patients, Malnourished patients were significantly more likely to be African American and have a lower BMI, but the age and sex were similar between the cohorts. The baseline comorbidity burden was significantly higher in the Malnourished cohort compared to the Nourished cohort. Compared to Nourished patients, Malnourished patients experienced significantly higher rates of one or more AEs (Nourished: 19.8% vs. Malnourished: 27.6%, p = 0.004) and serious AEs (Nourished: 15.2% vs. Malnourished: 22.6%, p < 0.001). Upon multivariate regression analysis, malnutrition was found to be an independent and associated with an extended LOS [aRR: 3.49, CI (1.97, 5.02), p < 0.001], NRD [saturated aOR: 1.76, CI (1.34, 2.32), p < 0.001], and unplanned readmission [saturated aOR: 1.42, CI (1.04, 1.95), p = 0.028]. Conclusions: Our study suggests that malnutrition increases the risk of postoperative complication, prolonged hospitalizations, non-routine discharges, and unplanned hospital readmissions. Further studies are necessary to identify the protocols that pre- and postoperatively optimize malnourished patients undergoing spinal surgery for metastatic spinal disease. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Racial disparities in the management and outcomes of primary osseous neoplasms of the spine: a SEER analysis.
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Elsamadicy, Aladine A., Sayeed, Sumaiya, Sherman, Josiah J. Z., Hengartner, Astrid C., Pennington, Zach, Hersh, Andrew M., Lo, Sheng-Fu Larry, Shin, John H., Mendel, Ehud, and Sciubba, Daniel M.
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Purpose: Primary osseous neoplasms of the spine, including Ewing's sarcoma, osteosarcoma, chondrosarcoma, and chordoma, are rare tumors with significant morbidity and mortality. The present study aims to identify the prevalence and impact of racial disparities on management and outcomes of patients with these malignancies. Methods: The 2000 to 2020 Surveillance, Epidemiology, and End Results (SEER) Registry, a cancer registry, was retrospectively reviewed to identify patients with Ewing's sarcoma, osteosarcoma, chondrosarcoma, or chordoma of the vertebral column or sacrum/pelvis. Study patients were divided into race-based cohorts: White, Black, Hispanic, and Other. Demographics, tumor characteristics, treatment variables, and mortality were assessed. Results: 2,415 patients were identified, of which 69.8% were White, 5.8% Black, 16.1% Hispanic, and 8.4% classified as "Other". Tumor type varied significantly between cohorts, with osteosarcoma affecting a greater proportion of Black patients compared to the others (p < 0.001). A lower proportion of Black and Other race patients received surgery compared to White and Hispanic patients (p < 0.001). Utilization of chemotherapy was highest in the Hispanic cohort (p < 0.001), though use of radiotherapy was similar across cohorts (p = 0.123). Five-year survival (p < 0.001) and median survival were greatest in White patients (p < 0.001). Compared to non-Hispanic Whites, Hispanic (p < 0.001) and "Other" patients (p < 0.001) were associated with reduced survival. Conclusion: Race may be associated with tumor characteristics at diagnosis (including subtype, size, and site), treatment utilization, and mortality, with non-White patients having lower survival compared to White patients. Further studies are necessary to identify underlying causes of these disparities and solutions for eliminating them. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery.
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Elsamadicy, Aladine A., Sayeed, Sumaiya, Sherman, Josiah J. Z., Craft, Samuel, Reeves, Benjamin C., Lo, Sheng-Fu Larry, Shin, John H., and Sciubba, Daniel M.
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CERVICAL spondylotic myelopathy ,FRAILTY ,MEDICAL care use ,LOGISTIC regression analysis ,SPINAL surgery - Abstract
Introduction: Frailty has been shown to negatively influence patient outcomes across many disease processes, including in the cervical spondylotic myelopathy (CSM) population. The aim of this study was to assess the impact that frailty has on patients with CSM who undergo anterior cervical discectomy and fusion (ACDF) or posterior cervical decompression and fusion (PCDF). Materials and Methods: A retrospective cohort study was performed using the 2016–2019 national inpatient sample. Adult patients (≥18 years old) undergoing ACDF only or PCDF only for CSM were identified using ICD codes. The patients were categorized based on receipt of ACDF or PCDF and pre-operative frailty status using the 11-item modified frailty index (mFI-11): pre-Frail (mFI = 1), frail (mFI = 2), or severely frail (mFI ≥ 3). Patient demographics, comorbidities, operative characteristics, perioperative adverse events (AEs), and healthcare resource utilization were assessed. Multivariate logistic regression analyses were used to identify independent predictors of extended length of stay (LOS) and non-routine discharge (NRD). Results: A total of 37,990 patients were identified, of which 16,665 (43.9%) were in the pre-frail cohort, 12,985 (34.2%) were in the frail cohort, and 8340 (22.0%) were in the severely frail cohort. The prevalence of many comorbidities varied significantly between frailty cohorts. Across all three frailty cohorts, the incidence of AEs was greater in patients who underwent PCDF, with dysphagia being significantly more common in patients who underwent ACDF. Additionally, the rate of adverse events significantly increased between ACDF and PCDF with respect to increasing frailty (p < 0.001). Regarding healthcare resource utilization, LOS and rate of NRD were significantly greater in patients who underwent PCDF in all three frailty cohorts, with these metrics increasing with frailty in both ACDF and PCDF cohorts (LOS: p < 0.001); NRD: p < 0.001). On a multivariate analysis of patients who underwent ACDF, frailty and severe frailty were found to be independent predictors of extended LOS [(frail) OR: 1.39, p < 0.001; (severely frail) OR: 2.25, p < 0.001] and NRD [(frail) OR: 1.49, p < 0.001; (severely frail) OR: 2.22, p < 0.001]. Similarly, in patients who underwent PCDF, frailty and severe frailty were found to be independent predictors of extended LOS [(frail) OR: 1.58, p < 0.001; (severely frail) OR: 2.45, p < 0.001] and NRD [(frail) OR: 1.55, p < 0.001; (severely frail) OR: 1.63, p < 0.001]. Conclusions: Our study suggests that preoperative frailty may impact outcomes after surgical treatment for CSM, with more frail patients having greater health care utilization and a higher rate of adverse events. The patients undergoing PCDF ensued increased health care utilization, compared to ACDF, whereas severely frail patients undergoing PCDF tended to have the longest length of stay and highest rate of non-routine discharge. Additional prospective studies are necessary to directly compare ACDF and PCDF in frail patients with CSM. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Academic career progression in AANS/CNS Spine Section award recipients.
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Elsamadicy, Aladine A., Sherman, Josiah J. Z., Craft, Samuel, Virk, Michael, Elder, Benjamin D., Bonfield, Christopher M., Snyder, Laura A., Ray, Wilson Z., Jones, Kristen E., and Ryu, Won Hyung A.
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- 2024
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6. Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Primary Spinal Intradural/Cord Tumors.
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Elsamadicy, Aladine A., Koo, Andrew B., Reeves, Benjamin C., Pennington, Zach, Sarkozy, Margot, Hersh, Andrew, Havlik, John, Sherman, Josiah J. Z., Goodwin, C. Rory, Kolb, Luis, Laurans, Maxwell, Larry Lo, Sheng-Fu, Shin, John H., and Sciubba, Daniel M.
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DISEASE risk factors ,FRAILTY ,SPINAL surgery ,SPINAL cord tumors ,HOSPITAL costs ,UMBILICAL cord clamping - Abstract
Objective: The Hospital Frailty Risk Score (HFRS) is a metric that measures frailty among patients in large national datasets using ICD-10 codes. While other metrics have been utilized to demonstrate the association between frailty and poor outcomes in spine oncology, none have examined the HFRS. The aim of this study was to investigate the impact of frailty using the HFRS on complications, length of stay, cost of admission, and discharge disposition in patients undergoing surgery for primary tumors of the spinal cord and meninges. Methods: A retrospective cohort study was performed using the Nationwide Inpatient Sample database from 2016 to 2018. Adult patients undergoing surgery for primary tumors of the spinal cord and meninges were identified using ICD-10-CM codes. Patients were categorized into 2 cohorts based on HFRS score: Non-Frail (HFRS<5) and Frail (HFRS≥5). Patient characteristics, treatment, perioperative complications, LOS, discharge disposition, and cost of admission were assessed. Results: Of the 5955 patients identified, 1260 (21.2%) were Frail. On average, the Frail cohort was nearly 8 years older (P <.001) and experienced more postoperative complications (P =.001). The Frail cohort experienced longer LOS (P <.001), a higher rate of non-routine discharge (P =.001), and a greater mean cost of admission (P <.001). Frailty was found to be an independent predictor of extended LOS (P <.001) and non-routine discharge (P <.001). Conclusion: Our study is the first to use the HFRS to assess the impact of frailty on patients with primary spinal tumors. We found that frailty was associated with prolonged LOS, non-routine discharge, and increased hospital costs. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Impact of insurance status on healthcare resource utilization and outcomes in adolescent patients presenting with spinal cord injuries.
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Sandhu, Mani Ratnesh S., David, Wyatt B., Reeves, Benjamin C., Sherman, Josiah J. Z., Craft, Samuel, Jayaraj, Christina, Boroumand, Sam, Clappier, Mona, Gutierrez, Alan, Sarkozy, Margot, Koo, Andrew B., Tuason, Dominick A., DiLuna, Michael L., and Elsamadicy, Aladine A.
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- 2023
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8. Socioeconomic and Racial/Ethnic Disparities in Perception of Health Status and Literacy in Spine Oncological Patients.
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Elsamadicy, Aladine A., Wang, Chelsea, Reeves, Benjamin C., Sherman, Josiah J. Z., Craft, Samuel, Rajjoub, Rami, Koo, Andrew, Hersh, Andrew M., Pennington, Zach, Sheng-Fu Larry Lo, Shin, John H., Mendel, Ehud, and Sciubba, Daniel M.
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- 2023
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9. A current review of spinal meningiomas: epidemiology, clinical presentation and management.
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Elsamadicy, Aladine A., Reeves, Benjamin C., Craft, Samuel, Sherman, Josiah J. Z., Koo, Andrew B., Sayeed, Sumaiya, Sarkozy, Margot, Kolb, Luis, Lo, Sheng-Fu Larry, Shin, John H., Sciubba, Daniel M., and Mendel, Ehud
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Purpose: To provide an up-to-date review of the epidemiology, histopathology, molecular biology, and etiology of spinal meningiomas, as well as discuss the clinical presentation, clinical evaluation, and most recent treatment recommendations for these lesions. Methods: PubMed and Google Scholar search was performed for studies related to meningiomas of the spine. The terms "meningioma," "spinal meningioma," "spine meningioma," "meningioma of the spine," "benign spinal tumors," and "benign spine tumors," were used to identify relevant studies. All studies, including primary data papers, meta-analyses, systematic reviews, general reviews, case reports, and clinical trials were considered for review. Results: Eighty-four studies were identified in the review. There were 22 studies discussing adverse postoperative outcomes, 21 studies discussing tumor genetics, 19 studies discussing epidemiology and current literature, 9 studies discussing radiation modalities and impact on subsequent tumor development, 5 studies on characteristic imaging findings, 5 studies discussing hormone use/receptor status on tumor development, 2 discussing operative techniques and 1 discussing tumor identification. Conclusion: Investigations into spinal meningiomas generally lag behind that of intracranial meningiomas. Recent advancements in the molecular profiling of spinal meningiomas has expanded our understanding of these tumors, increasing our appreciation for their heterogeneity. Continued investigation into the defining characteristics of different spinal meningiomas will aid in treatment planning and prognostication. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Arthroplasty implants and materials: Cost awareness and value perception.
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Gardezi, Mursal, Ottesen, Taylor D., Tyagi, Vineet, Sherman, Josiah J. Z., Grauer, Jonathan N., and Rubin, Lee E.
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ARTHROPLASTY ,NURSES ,PHYSICIANS ,MEDICAL care costs ,STANDARD deviations ,SURGICAL clinics ,OPERATING rooms - Abstract
Arthroplasty procedures are commonly performed and contribute to healthcare expenditures seen in the United States. Surgical team members may make selections among implants and materials without always knowing their relative cost. The current study reports on a survey aimed to investigate the perceptions of an academic group about the relative cost and value of commonly used operating room implants and materials related to joint arthroplasty cases using 10 matched pairs of items. Of the 124 persons eligible to take the survey, 102 responded (response rate of 82.3%) including attendings, fellows, residents, physician assistants (PAs), advanced practice registered nurses (APRNs) and registered nurses (RNs). On average for the ten pairs of items, the more expensive items were correctly selected by 90.2+/-13.9% (mean+/- standard deviation) of respondents with a range from 54.9% to 100%. Of note, the cost differences were significantly overestimated for 8/10 item pairs. The majority of respondents perceived the more expensive item as the item with the higher clinical value for 9/10 item pairs. Most arthroplasty attendings (91.3%) indicated willingness to use the less expensive item of two similar items. Nonetheless, 17.9% of fellows, residents, PAs, APRNs and RNs indicated that they would not feel comfortable suggesting using the less expensive item. Although attending arthroplasty surgeons stated a desire to consider costs, a knowledge deficit with regards to identifying the extent of cost differences was identified, and a significant portion of the surgical support team reported being hesitant to suggest less expensive options. [ABSTRACT FROM AUTHOR]
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- 2021
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