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This study aims to examine the seasonal spatial variability of column-averaged of dry air mole fraction of CO2 (XCO2) and Solar induced chlorophyll fluorescence (SIF) in the state of Mato Grosso in the Midwest region of Brazil, employing ordinary kriging (OK) as the spatial interpolation method. The XCO2 and SIF remote sensing data were collected on the Orbiting Carbon Observatory-2 (OCO-2) platform. Descriptive statistical analysis also incorporated spatial variability by using OK on the data that had been segregated into dry and wet seasons. The wet season mean for XCO2 ranged from 393.96 ± 0.10 to 394.14 ± 0.10 ppm between 2015 and 2018, and no variation in the mean of XCO2 was observed between these years in the dry season. SIF was higher in the rainy season compared to the dry season. A significant and more substantial negative relationship (r = − 0.84, p < 0.01) was observed between XCO2 and SIF. Higher values of XCO2 and SIF were observed in the northern region of the state, under the Amazon biome. Therefore, the seasonal variability of XCO2 in the Mato Grosso State, Brazil, is positively related to SIF. It indicates that photosynthesis plays an essential role in this carbon dynamics under regional conditions. [ABSTRACT FROM AUTHOR]

BACKGROUND: Coffee (Coffea arabica L.) is one of the most important commodities today, with a high economic value worldwide. Coffee leaf rust (Hemileia vastatrix Berk. et Br.) has been showing a high impact on Brazilian coffee trees among the various diseases that attack coffee. The climate has a great influence on the development of diseases, especially when fungi are the causal agents. This study aimed to carry out the zoning of climate favorability for coffee leaf rust in the traditional and main coffee‐producing regions of Brazil. The study was conducted in 13 locations in the states of Paraná, São Paulo, Rio de Janeiro, Espírito Santo, Minas Gerais, Goiás and Bahia. Air temperature and daily precipitation data for the current scenario were collected using the WorldClim version 2.1 platform for the last climatological normal and future climate change data. The ideal climate conditions for coffee leaf rust consist of a mean air temperature ranging from 21 to 25 °C and precipitation >30 mm per month. The Coupled Model Intercomparison Projects scenarios associated with the Intergovernmental Panel on Climate Change reports consisted of the Shared Socio‐Economic Pathways SSP‐1 2.6, SSP‐2 4.5, SSP‐3 7.0 and SSP‐5 8.5, the latter being considered one of the most catastrophic. All steps to carry out the suitability zoning were performed in a tool using the QGIS geographic information system software. RESULTS: Zoning for coffee leaf rust had three classes: favorable, relatively favorable and unfavorable. Currently, the largest coffee‐producing region in Brazil has 49.1% of its analyzed area classified as favorable, 39.2% as relatively favorable and 11.7% as unfavorable. In the current scenario, Patrocínio and Três Pontas are locations with high coffee production in which the favorable class is predominant. The state of Minas Gerais has an annual mean of 55.3% of its entire territory apt for the disease, with the highest occurrence between September and March. CONCLUSIONS: Climate change has a negative impact on the development of coffee leaf rust, mainly in the long term, as in the period of 2081–2100, in which the SSP‐5 8.5 scenario led to a decrease in the favorable and unfavorable areas and an increase in the relatively favorable areas of 9.8%, 18.6% and 71.5% for the Brazilian territory, respectively. © 2024 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Introduction: Erosive tooth wear (ETW) is a multifactorial condition of increasing prevalence in the younger population. This study aimed to explore the association between different ETW phenotypes with MMP2 and COMT single-nucleotide variants and selected environmental factors. Methods: Saliva samples, erosive wear, and dental caries experience data and dietary/behavioral information from 16- to 18-year-old patients (n = 747) were used. Genotypes were obtained, and phenotypes were further analyzed considering diet and behavioral data, using logistic regression as implemented in PLINK, with an alpha of 0.05. Results: When comparing individuals' ETW-free with those with mild ETW, an association was found with COMT rs6269 (p = 0.02). The comparison between ETW-free individuals with individuals with severe ETW also showed an association with COMT rs6269 under the recessive model (p = 0.03). Logistic regression showed that in the presence of less common alleles of MMP2 rs9923304 and COMT rs6269, ETW was more likely to occur when individuals drank wine. The GG genotype of COMT rs6269 was associated with the presence of lower (p = 0.02) and higher (p = 0.02) caries experience when individuals with ETW only in enamel were compared with individuals with ETW involving dentin. Conclusion: The results support a role of genes in ETW, with wine consumption being identified as a significant modulator, suggesting that gene-environment interactions may contribute to the development of ETW. [ABSTRACT FROM AUTHOR]

Sugarcane crops have a long cycle with successive harvests before re-planting, and row gaps are one of the main problems associated with the yield. The objective of this study was to establish an alternative methodology for measuring the planting and regrowth of sugarcane rows using UAV (Unmanned Aerial Vehicle) images and to compare it with manual measurements. This study was conducted in a 1 ha experimental area under mechanized harvesting. The reference methodology consists of measuring the continuous distances without regrowth between two plants along a planting row, considering distances greater than 0.50 m as gaps and the following gaps classes: >0.5–1.0 m, >1.0–1.5 m, >1.5–2.0 m, >2.0–3.5 m, and >3.5 m. Images were collected from a UAV equipped with a 12-megapixel RGB camera. The number of regrowth gaps measured through imaging for the class of gaps with a length between 0.5 and 1.0 m was eight times higher than field measurement. In the class of gaps with a length between 1.0 and 1.5 m, the result is the opposite, as the field measurement was approximately three times higher than the UAV measurement, with a significant difference in both classes. In the other length classes analyzed, the number of gaps did not show significant differences. Our results suggest that regrowth gaps can be quickly estimated with the proposed methodology for gaps greater than 1.5 m. For gaps smaller than <1 m, the methodology using a UAV is not accurate. [ABSTRACT FROM AUTHOR]

The Brazilian experience of economic growth with social inclusion from 2004 to 2010 contrasts with the period between 2010 and 2015, in which economic growth was lower despite of the maintenance of the income transfer policies. Based on the Kaleckian theoretical model, we analyze how changes in the economic context altered the response of each aggregate demand component to shifts in income distribution, reducing the likelihood of wage-led regimes and possibly leading to a regime switch. While relevant to explaining specific economic contexts, the possibility of regime switches has been largely overlooked by the literature so far. The empirical estimations based on a SVAR model with an estimated structural break for the period between 2003 and 2015 confirm a reduction in the likelihood of a wage-led regime and suggest that wage-led economic regimes became profit-led after the break in 2010. Thus, the higher wage share had a positive impact on the Brazilian economy, but such effect weakened when the underlying economic conditions changed. [ABSTRACT FROM AUTHOR]

Barley (Hordeum vulgare) is a globally significant cereal crop, widely used in both food production and brewing. However, it is particularly vulnerable to climate change, especially extreme temperature fluctuations, which can severely reduce yields. To address this challenge, a detailed climate zoning study was conducted to assess the suitability of barley production areas across South America, considering both current conditions and future climate scenarios from the Intergovernmental Panel on Climate Change (IPCC). The study utilized historical climate data along with projections from the CMIP6 IPSL-CM6A-LR model for the period 2021–2100. Several indices, such as evapotranspiration, were calculated, and factors like soil composition and topography were integrated into the classification of regions based on their agricultural potential. Critical variables in this assessment included temperature, precipitation, and water or thermal excess. The results showed that 6.59% of South America's territory is currently suitable for barley cultivation without additional irrigation, with these regions concentrated primarily in temperate southern areas. In contrast, 18.62% of the region is already unsuitable due to excessive heat. Projections under future climate scenarios indicate a shrinking of suitable areas, alongside an expansion of unsuitable regions. In the worst-case scenario, only 1.48% of the territory would remain viable for barley farming. These findings emphasize the crop's vulnerability to climate change, underscoring the urgency of developing agricultural adaptation strategies. The predicted contraction in suitable barley cultivation areas demonstrates the profound impact of climate change on agriculture and highlights the need for proactive measures to ensure sustainable barley production in South America. [ABSTRACT FROM AUTHOR]

The chronic ingestion of pesticide residues through food appears to be a global public health issue, especially in Brazil. This study evaluates 120 menus across six Brazilian institutional restaurants, estimating the allowance of active pesticide ingredients, residue characterization, and chronic exposure risk through food. Data analysis reveals 263 authorized active ingredients, predominantly insecticides (43%), fungicides (40%), and herbicides (14%) for use in 40 foods. Notably, 4% of residues are extremely toxic, 5% highly toxic, and 14% moderately toxic. Forty-two compounds, especially those permitted in animal-source foods, exhibit high bioaccumulation potential. Some foods harbor multiple pesticide residues, raising concerns, despite 99% of residues falling within the Acceptable Daily Intake. Methomyl insecticide poses potential ingestion risks during lunch, warranting attention. The pervasive presence of pesticide residues in daily consumed foods underscores the necessity for greater attention to the source of the food, ensuring access to healthy and safe collective consumption. [ABSTRACT FROM AUTHOR]

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This in vitro study evaluated the protective effect of an Si-containing toothpaste associated with different fluoride concentrations by reducing the depth of the demineralized lesions in dentin after cariogenic pH cycling. Methods: Sixty bovine dentin blocks (4 × 4 × 2 mm) were randomly assigned into five groups (n = twelve/group): RGS1 (Si toothpaste with 1450 ppm F), RGS2 (Si toothpaste with 1100 ppm F), RGS3 (fluoride-free Si toothpaste), negative control (NC) (fluoride-free toothpaste), and positive control (PC) (1450 ppm F toothpaste). The specimens underwent a three-day pH cycling model simulating the oral environment with twice-daily brushing. The mineral loss (ΔF) and lesion depth (ΔFmax) were assessed using quantitative light-induced fluorescence (QLF), and scanning electron microscopy (SEM) provided a morphological analysis. Elemental analyses were performed with an energy-dispersive X-ray spectrometer (EDS). ANOVA and Tukey's test were used for the data analysis (α = 5%). Results: EDS confirmed the Si in the toothpaste formulations. The groups treated with fluoride silicon toothpastes (RGS1, RGS2) had significantly reduced mineral loss and lesion depth compared to the PC group. The NC group exhibited the greatest mineral loss and lesion depth. SEM images revealed occluded superficial dentin tubules and a protective mineral layer in the groups treated with Si toothpaste, whereas no deposition (NC group) or limited mineral deposition (PC group) was observed in the control groups. Conclusions: The findings suggest that the Si toothpastes favored protection against dentin demineralization, even at a lower concentration or free of fluoride, with dentin tubule occlusion, thus representing a promising oral care product over traditional fluoride toothpastes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Insect Conservation is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Mastitis is a disease that is considered an obstacle in dairy farming. Some methods of diagnosing mastitis have been used effectively over the years, but with an associated relative cost that reduces the producer's profit. In this context, this sector needs tools that offer an early, safe, and non-invasive diagnosis and that direct the producer to apply resources to confirm the clinical picture, minimizing the cost of monitoring the herd. The objective of this study was to develop a predictive methodology based on sequential knowledge transfer for the automatic detection of bovine subclinical mastitis using computer vision. The image bank used in this research consisted of 165 images, each with a resolution of 360 × 360 pixels, sourced from a database of 55 animals diagnosed with subclinical mastitis, all of which were not exhibiting clinical symptoms at the time of imaging. The images utilized in the sequential learning transfer were those of MammoTherm, which is used for the detection of breast cancer in women. The optimized model demonstrated the most optimal network performance, achieving 92.1% accuracy, in comparison to the model with manual search (86.1%). The proposed predictive methodologies, based on knowledge transfer, were effective in accurately classifying the images. This significantly enhanced the automatic detection of both healthy animals and those diagnosed with subclinical mastitis using thermal images of the udders of dairy cows. [ABSTRACT FROM AUTHOR]

Leprosy is a neglected contagious disease that causes physical disability and episodes of inflammation, called leprosy reactions. There are currently no consolidated laboratory markers that can predict or confirm the diagnosis of leprosy reactions, negatively impacting the progression of the disease. The aim of this study was to analyze the behavior of inflammatory biomarkers in a population of patients with multibacillary leprosy. This prospective study in a northeastern capital involved 67 new cases of multibacillary leprosy, assessing inflammatory biomarkers at diagnosis. Histopathology, qPCR, slit skin smear microscopy, and laboratory tests, including CRP-albumin, neutrophil-lymphocyte, lymphocyte-monocyte, platelet-lymphocyte ratios, and systemic immune-inflammation index, were conducted. Statistical analysis utilized Stata version 16.0®, employing Chi-square, Kruskal-Wallis, and Poisson regression (5% significance). The population, mainly young brown men with low socioeconomic status, borderline leprosy, and and degree of physical disability one, saw 19.4% experiencing leprosy reactions. Standard multibacillary multidrug therapy was administered to all. Ratios and index values exceeding medians were prevalent (46.3-47.8%). Assessing biological markers against leprosy reactions revealed a positive relation between reactions and lymphocyte-platelet ratio (p = 0.05) and a positive trend with the systemic immune-inflammation index (p = 0.06). Patients with reactions were 1.3 times more likely to exhibit an elevated lymphocyte-platelet ratio. The lymphocyte-platelet ratio emerged as a potential indicator for recognizing leprosy reactions. Further research is essential to validate these findings, aiming for earlier detection of leprosy reactions. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Reference evapotranspiration (ETo) is an important part of the water cycle, essential for climate studies, water resource management, and agricultural planning. However, accurate estimation of ETo is challenging when meteorological data are insufficient or of low quality. Furthermore, in climate change studies where large amounts of data need to be managed, it is important to minimize the complexity of the ETo calculation. This study presents a comprehensive approach that integrates data quality analysis with two calibration methods—annual and cluster-based—to improve ETo estimates based solely on temperature data from a set of weather stations (WS). First, the quality and integrity of meteorological data from several WS were analyzed to reduce uncertainty. Second, the Hargreaves–Samani equation (HS) is site calibrated using two approaches: (a) annual calibration, where the radiation coefficient (kRs) is adjusted using a data set covering the entire year; (b) cluster-based calibration, where independent radiation coefficients are adjusted for clusters of years and months. The methodology was evaluated for the Alentejo region in Southern Portugal, using data from 1996 to 2023. When using the original HS equation with a kRs = 0.17 °C−0.5, ETo was estimated with errors from 14.9% to 22.9% with bias ranging from −9.0% to 8.8%. The annual calibration resulted in kRs values between 0.157 and 0.165 °C−0.5 with estimation errors between 13.3% and 20.6% and bias ranging from −1.5% to 1.0% across the different weather stations. Calibration based on clusters of months and years produced unclear results. Dry season months showed better results using cluster-based calibration, while wet season months performed poorly regardless of the calibration approach. The results highlight the importance of meteorological data quality and site-specific calibration for refining temperature-based ETo estimation methods, and for the region studied, the gains do not justify the increased complexity of the cluster-based approach. [ABSTRACT FROM AUTHOR]

The Monastery of Alcobaça houses in reserve the ceramic tiles that adorned the floor of the church's apse. These tiles were removed during rehabilitation works and many preserve part of their original fixing mortars. A comprehensive analysis of 21 samples was conducted using a multi‐analytical approach (X‐ray fluorescence, X‐ray diffraction, scanning electron microscopy–energy‐dispersive X‐ray spectroscopy, μ‐Raman spectroscopy, thermogravimetry–differential thermal analysis, optical microscopy, and colorimetry). Results suggest compositional variations in the samples from the back and sides of the ceramic tiles; however, the mineralogy and general characteristics of the aggregates remained consistent between the samples and are coherent with the local geology, suggesting a shared historical origin. [ABSTRACT FROM AUTHOR]

We report the prenatal diagnosis of Poretti-Boltshauser Syndrome (PBS) in a 36-year-old primigravida woman. At 22 weeks and 6 days of gestation, fetal ultrasound revealed a normally shaped but hyperechogenic cerebellum with all supratentorial structures appearing normal. Differential diagnosis included cavernous hemangioma, capillary telangiectasia, and cerebellar hemorrhage. Subsequent fetal cerebral MRI showed diffuse bilateral cerebellar modifications, reduced cranio-caudal diameter of the vermis, and pathological elongation and thickening of the superior cerebellar peduncles indicative of the molar tooth sign. Amniocentesis and whole exome sequencing identified two heterozygous truncating variants in the LAMA1 gene: c.3099G > A (p.Trp1033Ter) and c.3699T > A (p.Tyr1233Ter), confirming PBS.) Following the diagnosis, the pregnancy was terminated at 23 weeks and 5 days. Post-mortem examination supported the MRI findings consistent with PBS. This case highlights the importance of integrating ultrasound, MRI, and genetic analysis for accurate prenatal diagnosis and emphasizes the molecular diversity associated with PBS, including the presence of molar tooth sign mimics and a novel c.3699T > A variant. [ABSTRACT FROM AUTHOR]

This study introduces two novel DEM-based distributed rainfall-runoff models derived from the existing Hidropixel model: HidropixelTUH+ and HidropixelDLR. These models account for spatial variations in direct runoff generation, translation, and storage within a watershed, considering spatial variability in rainfall and basin characteristics. In HidropixelTUH+, a Triangular Unit Hydrograph (TUH) is determined for each Digital Elevation Model (DEM) pixel and lagged to the watershed outlet based on the travel time from the pixel to the outlet. In HidropixelDLR, a hydrograph is estimated for each pixel based on the travel time, which takes translation effects into account. To represent the storage effects, this hydrograph is attenuated by a linear reservoir at each pixel. Both approaches were applied to the Upper Medway catchment (250 km2) in southeastern England, using rainfall data from a rain gauge network. The outcomes revealed that the proposed approaches provided a reasonably accurate prediction of the hydrographs and exhibited notably superior performance compared to the original version of Hidropixel, which has limited capabilities in capturing translation effects. HidropixelTUH+ and HidropixelDLR predicted peak flows with an average absolute error of 11% and 10%, respectively. The HidropixelDLR achieved a more accurate time-to-peak estimation, with an average absolute error of 1 h, compared to the 1.5-h error from HidropixelTUH+. Additionally, the HidropixelDLR predicted the full direct runoff hydrograph more accurately, achieving an average Nash–Sutcliffe coefficient (NSE) of 0.89, while the HidropixelTUH+ had an NSE of approximately 0.84. [ABSTRACT FROM AUTHOR]

Mimosa tenuiflora (Willd.) Poir. is a native species of tropical regions with a diverse therapeutic potential due to the presence of various metabolites in its botanical composition. This review provides updated information on the phytochemistry and pharmacological activities of M. tenuiflora. The studies used in this review were obtained from specialized databases (PubMed, Scielo, Science Direct, Web of Science, Springer, and Scopus) using the keywords: Mimosa tenuiflora, phytochemistry, and pharmacological activity. The selected articles were analyzed by year of publication, country where the research was conducted, isolated chemical compounds reported, and biological activities evaluated. The selected articles were peer-reviewed in the following order: title, abstract, and full text. While the majority of studies involving M. tenuiflora are still situated in Brazil and Mexico, some research is being conducted outside of Latin America. In vitro and in vivo studies report various pharmacological activities for M. tenuiflora, such as antimicrobial, antiparasitic, antioxidant, anti-inflammatory, antinociceptive, and antidepressant effects. These diverse activities are attributed to the presence of flavonoids and alkaloids, identified as the main classes of secondary metabolites in M. tenuiflora. The effective doses for biological activities vary according to the plant part used and the type of extracting solvent. Additionally, the isolation and concentration of the bioactive compound optimizes and reduces the potential effective therapeutic dose. The arsenal of bioactive compounds provides versatility for potential therapeutic uses of M. tenuiflora. Despite its therapeutic potential, clinical trials are still lacking, and preclinical studies remain limited and heterogeneous, representing an opportunity for further pharmacological investigation. [ABSTRACT FROM AUTHOR]

Inhibition of HIV-1 protease is a cornerstone of antiretroviral therapy. However, the notorious ability of HIV-1 to develop resistance to protease inhibitors (PIs), particularly darunavir (DRV), poses a major challenge. Using quantum chemistry and computer simulations, this study aims to investigate the interactions between two novel PIs, GRL-004 and GRL-063, as well as a wild-type (WT) HIV strain and a DRV-resistant mutant strain. To do this, we used molecular docking, molecular dynamics simulations, and quantum mechanical calculations to check how well GRL-004 and GRL-063 bound to both WT and DRV-resistant proteases. The results show that GRL-004 and GRL-063 bind very well to ASP29 in the WT strain. ASP29 is an important amino acid in the HIV protease dimer. Remarkably, amino acids such as ILE50 in the WT strains showed substantial binding energies to both drugs. Quantum energy calculations showed a slight reduction in the energy affinity of the interaction between the MUT strain and the ligand GRL-063, compared to the WT strain. GRL-004 showed similar interaction energy for both strains, suggesting that it has greater plasticity than GRL-063 despite its lower interaction affinity. Furthermore, GLY49B demonstrated strong binding energies regardless of mutations. Other relevant residues with strong binding energies include GLY49B, PHE82A, PRO81A, ASP29A, ASP25A and ALA28B. This study improves our understanding of receptor–ligand dynamics and the adaptability of new protease inhibitors (PIs), which has profound implications for the innovation of future antiretroviral drugs. [ABSTRACT FROM AUTHOR]

Aim: To evaluate in vitro the effect of laser photobiomodulation (PBM) combined or not with 30-nm hydroxyapatite nanoparticles (HANp), on the osteogenic differentiation of human umbilical cord mesenchymal stem cells (hUC-MSCs) by morphometric analysis using artificial intelligence programs (TensorFlow and ArcGIS). Methods: UC-MSCs were isolated and cultured until 80% confluence was reached. The cells were then plated according to the following experimental groups: G1 –control (DMEM), G2 –BMP-2, G3 –BMP-7, G4 –PBM (660 nm, 10 mW, 2.5 J/cm2, spot size of 0.08 cm2), G5 –HANp, G6 –HANp + PBM, G7 –BMP-2 + PBM, and G8 –BMP-7 + PBM. The MTT assay was used to analyze cell viability at 24, 48 and 72 h. Osteogenic differentiation was assessed by Alizarin Red staining after 7, 14 and 21 days. For morphometric analysis, areas of osteogenic differentiation (pixel2) were delimited by machine learning using the TensorFlow and ArcGIS 10.8 programs. Results: The results of the MTT assay showed high rates of cell viability and proliferation in all groups when compared to control. Morphometric analysis revealed a greater area of osteogenic differentiation in G5 (HANp = 142709,33±36573,39) and G6 (HANp + PBM = 125452,00±24226,95) at all time points evaluated. Conclusion: It is suggested that HANp, whether combined with PBM or not, may be a promising alternative to enhance the cellular viability and osteogenic differentiation of hUC-MSCs. [ABSTRACT FROM AUTHOR]

An interesting feature in dissipative nonlinear systems is the emergence of characteristic domains in parameter space that exhibit periodic temporal evolution, known as shrimp-shaped domains. We investigate the parameter space of the dissipative asymmetric kicked rotor map and show that, in the regime of strong dissipation, the shrimp-shaped domains repeat themselves as the nonlinearity parameter increases while maintaining the same period. We analyze the dependence of the length of each periodic domain with the nonlinearity parameter, revealing that it follows a power law with the same exponent regardless of the dissipation parameter. Additionally, we find that the distance between adjacent shrimp-shaped domains is scaling invariant with respect to the dissipation parameter. Furthermore, we show that for weaker dissipation, a multistable scenario emerges within the periodic domains. We find that as the dissipation gets weaker, the ratio of multistable parameters for each periodic domain increases, and the area of the periodic basin decreases as the nonlinearity parameter increases. [ABSTRACT FROM AUTHOR]

We investigate some statistical properties of escaping particles in a billiard system whose boundary is described by two control parameters with a hole on its boundary. Initially, we analyze the survival probability for different hole positions and sizes. We notice that the survival probability follows an exponential decay with a characteristic power-law tail when the hole is positioned partially or entirely over large stability islands in phase space. We find that the survival probability exhibits scaling invariance with respect to the hole size. In contrast, the survival probability for holes placed in predominantly chaotic regions deviates from the exponential decay. We introduce two holes simultaneously and investigate the complexity of the escape basins for different hole sizes and control parameters by means of the basin entropy and the basin boundary entropy. We find a non-trivial relation between these entropies and the system's parameters and show that the basin entropy exhibits scaling invariance for a specific control parameter interval. [ABSTRACT FROM AUTHOR]

In many countries, complex environmental problems such as biodiversity decline are regulated at the national level by a disparate range of laws and nonstatutory policy instruments variously described by terms including plans, strategies, guidelines, statements of intent, and/or incentives. Such instruments are often grouped together by conservation policymakers and scientists under the umbrella term "policy." However, from a legal perspective, there are critical differences between these so‐called policy instruments. In this paper, we focus on what we consider to be the critical difference: whether a policy instrument is binding, and therefore whether an administrative decision (e.g., about a development proposal) can be legally challenged due to noncompliance with that policy instrument. Drawing from international examples, the aim of this paper is to give conservation policymakers and scientists the guidance needed to critically differentiate between laws and nonstatutory policy, assess current or proposed policies, and determine whether a nonstatutory instrument gives rise to binding obligations, thus allowing for decisions to be challenged before a court. In doing so, we encourage conservation scientists, policymakers, activists, and practitioners to reflect critically on what is possible and not possible when nonstatutory "policy" instruments are designed and implemented. [ABSTRACT FROM AUTHOR]

Background/Objectives: Treatment of patients with myocardial ischemic diseases crucially involves cardiac reperfusion (CR). However, oxidative stress and tissue lesions caused by CR may also lead to lethal complications, such as arrythmias and vasoplegic syndrome (VS). Although methylene blue (MB) has long been used to treat VS due to cardiac ischemia and reperfusion (CIR) and/or surgery because of its vascular effects, MB's effects on the heart are unclear. Therefore, we investigated the potential cardioprotective or arrhythmogenic effects of MB in an animal model of CIR. To this end, 12–16-week-old male Wistar rats were divided into four experimental groups: (a) rats subjected to SHAM surgery with no ischemia; (b) rats subjected to CIR and treated with a vehicle (SS + CIR); and (c) rats subjected to CIR and treated with 2 mg/kg i.v. MB before ischemia (MB + ISQ) or (d) after ischemia but before reperfusion (ISQ + MB). An ECG analysis was used to evaluate the incidence of ventricular arrhythmias (VAs), atrioventricular blocks (AVBs), and lethality (LET) resulting from CIR. After CIR, rat hearts were removed for histopathological analysis and lipid hydroperoxide (LH) measurements. Results: The incidence of VA, AVB, and LET was significantly increased in the MB + ISQ group (VA = 100%; AVB = 100%; LET = 100%) but significantly reduced in the ISQ + MB group (VA = 42.8%; AVB = 28.5%; LET = 21.4%) compared with the SS + CIR group (VA = 85.7%; AVB = 71.4%; LET = 64.2%). LH concentration was significantly reduced in both MB-treated groups, but myocardial injuries were increased only in the MB + ISQ group when compared with the SS + CIR group. Conclusions: These results indicate that MB produces a biphasic effect on CIR, with cardiotoxic effects when administered before cardiac ischemia and cardioprotective effects when administered after ischemia but before cardiac reperfusion. [ABSTRACT FROM AUTHOR]

Genipa americana L. is popularly known as jenipapo and has a potential herbal medicine with various pharmacological activities. Granules is a simple and useful pharmaceutical form to obtain herbal medicines in solid-state and has advantage due to protection of the bioactive compounds herbal extract. The aim of this study was to conduct studies of characterization of Genipa americana extract and its granules to evaluate their phytochemical, physicochemical and thermal properties. The crude extract of Genipa americana leaves was obtained by maceration using ethanol. A total of four Genipa americana granules were obtained using wet granulation process. Phytochemical characterization was performed: total phenol and total flavonoid contents and DPPH, FRAP and MDA assays. Physicochemical characterization was performed using SEM, FTIR, UV–Vis, dissolution profile and UFLC-DAD/UV analysis. Thermal characterization was performed using TG technique. The crude extract of Genipa americana and its granules showed the presence of iridoids (genipin and geniposides), flavonoids and phenolic compounds and genipin derivatives after hydrolysis experiment using the UFLC-DAD/UV. The DPPH assay showed antioxidant activity with an IC50 of 207.07 µg cm−3 for the Genipa americana extract and 198.34 to 298.71 µg cm−3 for the Genipa americana granules. The FRAP assay showed a good ability to reduce the iron III–TPTZ complex to iron II–TPTZ with values between 1092 and 1532 µM ferrous sulfate. g−1 also explained by the presence of phenolic compounds and flavonoids. The maloaldehyde (MDA) assay showed acceptable levels and similar to the scientific literature. SEM analysis showed granules with morphology and particle size that characterize them as microparticles. FTIR analysis showed similarity between the identification bands of the crude Genipa americana granules with pharmaceutical excipients. The dissolution profiles of the Genipa americana granules showed characteristics of highly water-soluble pharmaceutical compositions with total release of the genipin marker between 30 and 60 min. The Genipa americana granules showed moisture content between 4.27 and 11.6% by the thermogravimetric analysis. The granules indicated greater protection and stability for the Genipa americana extract in these pharmaceutical formulations. The wet granulation process proved to be suitable and low-cost for Genipa americana extract. The moisture content of the granules can cause variability in genipin content to be stored in appropriate environment and packaging. [ABSTRACT FROM AUTHOR]

Purpose: Evaluate the immunohistochemical expression of the ING3 in actinic cheilitis and squamous cell carcinoma of the lower lip. Methods: Forty-five specimens of actinic cheilitis and 48 specimens of squamous cell carcinoma of the lower lip were submitted to immunohistochemical detection of ING3. The protein expression in different cellular sublocations was compared between the two groups, and associations with the clinicopathological variables were analyzed. A significance level of 5% was adopted for all tests. Results: Deaths were significantly more frequent in tumors with a high histopathological risk score (p < 0.05). In actinic cheilitis, significant differences were found in the nucleus-cytoplasmic expression of ING3 and expression restricted to the cytoplasm with binary histopathological grading (p < 0.05). In squamous cell carcinoma of the lower lip, there was no statistically significant difference when comparing ING3 expressions with clinical and morphological parameters (p > 0.05). Nucleo-cytoplasmic ING3 expression was significantly lower in squamous cell carcinoma of the lower lip when compared to actinic cheilitis (p < 0.05) and the expression restricted to the cytoplasm was significantly higher in squamous cell carcinoma of the lower lip (p < 0.05). Conclusion: The results of this study suggest that there is a marked decrease in the nuclear expression of ING3 as malignant progression occurs, indicating an impaired tumor suppressor function of this protein in actinic cheilitis and squamous cell carcinoma of the lower lip. [ABSTRACT FROM AUTHOR]

Capsicum annuum L. has worldwide distribution, but drought has limited its production. There is a lack of research to better understand how this species copes with drought stress, whether it is reversible, and the effects of mitigating agents such as salicylic acid (SA). Therefore, this study aimed to understand the mechanisms of action of SA and rehydration on the physiology of pepper plants grown under drought conditions. The factorial scheme adopted was 3 × 4, with three water regimes (irrigation, drought, and rehydration) and four SA concentrations, namely: 0 (control), 0.5, 1, and 1.5 mM. This study evaluated leaf water percentage, water potential of shoots, chlorophylls (a and b), carotenoids, stomatal conductance, chlorophyll a fluorescence, and hydrogen peroxide (H2O2) concentration at different times of day, water conditions (irrigation, drought, and rehydration), and SA applications (without the addition of a regulator (0) and with the addition of SA at concentrations equal to 0.5, 1, and 1.5 mM). In general, exogenous SA application increased stomatal conductance (gs) responses and modified the fluorescence parameters (ΦPSII, qP, ETR, NPQ, D, and E) of sweet pepper plants subjected to drought followed by rehydration. It was found that the use of SA, especially at concentrations of 1 mM in combination with rehydration, modulates gs, which is reflected in a higher electron transport rate. This, along with the production of photosynthetic pigments, suggests that H2O2 did not cause membrane damage, thereby mitigating the water deficit in pepper plants. Plants under drought conditions and rehydration with foliar SA application at concentrations of 1 mM demonstrated protection against damage resulting from water stress. Focusing on sustainable productivity, foliar SA application of 1 mM could be recommended as a technique to overcome the adverse effects of water stress on pepper plants cultivated in arid and semi-arid regions. [ABSTRACT FROM AUTHOR]

Summary: The association between nightmare frequency (NMF) and suicidal ideation (SI) is well known, yet the impact of the COVID‐19 pandemic on this relation is inconsistent. This study aimed to investigate changes in NMF, SI, and their association during the COVID‐19 pandemic. Data were collected in 16 countries using a harmonised questionnaire. The sample included 9328 individuals (4848 women; age M[SD] = 46.85 [17.75] years), and 17.60% reported previous COVID‐19. Overall, SI was significantly 2% lower during the pandemic vs. before, and this was consistent across genders and ages. Most countries/regions demonstrated decreases in SI during this pandemic, with Austria (−9.57%), Sweden (−6.18%), and Bulgaria (−5.14%) exhibiting significant declines in SI, but Italy (1.45%) and Portugal (2.45%) demonstrated non‐significant increases. Suicidal ideation was more common in participants with long‐COVID (21.10%) vs. short‐COVID (12.40%), though SI did not vary by COVID‐19 history. Nightmare frequency increased by 4.50% during the pandemic and was significantly higher in those with previous COVID‐19 (14.50% vs. 10.70%), during infection (23.00% vs. 8.10%), and in those with long‐COVID (18.00% vs. 8.50%). The relation between NMF and SI was not significantly stronger during the pandemic than prior (rs = 0.18 vs. 0.14; z = 2.80). Frequent nightmares during the pandemic increased the likelihood of reporting SI (OR = 1.57, 95% CI 1.20–2.05), while frequent dream recall during the pandemic served a protective effect (OR = 0.74, 95% CI 0.59–0.94). These findings have important implications for identifying those at risk of suicide and may offer a potential pathway for suicide prevention. [ABSTRACT FROM AUTHOR]

Remote sensing has proven to be a vital tool for monitoring and forecasting the quality and yield of crops. The utilization of innovative technologies such as Solar-Induced Fluorescence (SIF) and satellite measurements of column-averaged CO2 (xCO2) can enhance these estimations. SIF is a signal emitted by crops during photosynthesis, thus indicating photosynthetic activities. The concentration of atmospheric CO2 is a critical factor in determining the efficiency of photosynthesis. The aim of this study was to investigate the correlation between satellite-derived Solar-Induced Chlorophyll Fluorescence (SIF), column-averaged CO2 (xCO2), and Normalized Difference Vegetation Index (NDVI) and their association with sugarcane yield and sugar content in the field. This study was carried out in south-central Brazil. We used four localities to represent the region: Pradópolis, Araraquara, Iracemápolis, and Quirinópolis. Data were collected from orbital systems during the period spanning from 2015 to 2016. Concurrently, monthly data regarding tons of sugarcane per hectare (TCH) and total recoverable sugars (TRS) were gathered from 24 harvest locations within the studied plots. It was observed that TRS decreased when SIF values ranged between 0.4 W m−2 sr−1 μm−1 and 0.8 W m−2 sr−1 μm−1, particularly in conjunction with NDVI values below 0.5. TRS values peaked at 15 kg t−1 with low NDVI and xCO2 values, alongside SIF values lower than 0.4 W m−2 sr−1 μm−1 and greater than 1 W m−2 sr−1 μm−1. These findings underscore the potential of integrating SIF, xCO2, and NDVI measurements in the monitoring and forecasting of yield and sugar content in sugarcane crops. [ABSTRACT FROM AUTHOR]

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In this work, a reconfigurable frequency-selective surface (FSS) with a very simple biasing network that offers single- or multi-band response is presented. The proposed structure is formed by the V-shaped elements on a single-sided dielectric substrate. A PIN diode is used as active device to make the FSS reconfigurable, and bias lines are inserted for feeding. Initial analysis is performed with passive FSSs to predict the behavior of the proposed reconfigurable structure. The proposed reconfigurable FSS is then designed and evaluated. Three biasing-state configurations are analyzed: off-state, on-state, and intermediate-state. Depending on the state applied to the FSS, it can exhibit single switchable resonance frequency or multi-band response with a Fano resonance. [ABSTRACT FROM AUTHOR]

Phytoremediation is a rapidly expanding process due to its technical and economic viability. The objective of this work was to evaluate the phytoremediation potential of Helianthus annuus in three cultivation media: artificially contaminated Catalão soil, hydroponics and roadside soil. In hydroponics, ZnCl2 doses 0.32 mgL− 1, 29.94 mgL− 1, 60.06 mgL− 1, 119.94 mgL− 1 were used. While in the artificially contaminated soil, the doses were 0 mgkg− 1, 299 mgkg− 1, 599 mgkg− 1, 1498 mgkg− 1. Physiological analyzes made it possible to demonstrate that treatments T3 and T4, with the highest concentrations of the metal, inhibited growth and promoted darkening of the roots. The highest Zn contents occurred in the aerial part. The results indicated that Helianthus annuus was classified as hyperaccumulator due to its ability to accumulate high levels of Zn mainly in artificially contaminated soil. [ABSTRACT FROM AUTHOR]

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Featured Application: This research underscores the potential of Portuguese oregano and thyme accessions as rich sources of diverse phenolic compounds, particularly flavonoids and phenolic acids, which have been less studied compared to the dominant monoterpenes thymol and carvacrol. These compounds contribute significantly to the antioxidant properties of the plants, offering potential applications in the food industry. By incorporating these unique phenolic profiles into food formulations or active packaging, the antioxidant benefits can enhance the food shelf life, improve the nutritional value, and support health and well-being. This makes these accessions valuable for developing innovative, healthier food products. Oregano (Origanum vulgare L.) and thyme (Thymus mastichina L.) are popular aromatic plants used in the culinary sphere and are known for their antioxidant capacity. This study investigates the variability in the antioxidant capacity and phenolic profiles, focusing on flavonoids and phenolic acids, of oregano and thyme accessions from the Portuguese Bank of Plant Germplasm. The antioxidant capacity was assessed by measurements using the ferric-ion-reducing antioxidant power and DPPH radical scavenging activity assays, Total Phenolic Content, and individual phenolic compounds. Oregano extracts presented the highest total phenolic content (~2152 mg GAE/g DW), while thyme extracts showed the highest ferric-reducing antioxidant powers. However, both aromatic plants (~0.58 mmol TE/g DW) presented similar DPPH radical scavenging capacities. Rosmarinic acid was the major phenolic compound in methanolic extracts from oregano and thyme, but higher amounts were found in thyme (23.11 to 40.45 mg/g DW). The accessions of oregano and thyme showed statistical differences in the phenolic content and antioxidant capacity. This study provides valuable insights into the phenolic profile of Portuguese oregano and thyme, which could constitute potential sources of natural antioxidants and bioactive compounds, to be used by the food industry as natural food additives. [ABSTRACT FROM AUTHOR]

Copyright of Id on Line. Revista de Psicologia is the property of Id on Line Revista Multidisciplinar e de Psicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The present study aimed to analyze the antifungal, antioxidant, and irritant potential of citronella oil, both isolated and combined with caffeic acid phenethyl ester (CAPE), for topical oral candidiasis. The antioxidant potential was evaluated using two methods, the DPPH test and the reducing power test (FRAP), while the irritant potential of the solutions was assessed through the hen's egg chorioallantoic membrane test (HET-CAM). The DPPH test (IC50) values for the CITRO III + CAPE III combination were 32 ± 9 mg/mL, and for isolated CAPE, 13 ± 3 mg/mL. The results from the FRAP method revealed a low iron-reducing power for the combination of 1.25 mg/mL of citronella and 0.0775 mg/mL of CAPE (CITRO III + CAPE III), showing no significant difference compared to the isolated solution of 0.15 mg/mL of CAPE. The antibacterial activity of CAPE and isolated citronella in vitro against microorganisms was evaluated using two methods: microdilution and biofilm assay. The results showed that the MIC and MFC values were 0.5 mg/mL for citronella at both tested times (24 h and 48 h). For CAPE, the MFC values were 0.031 mg/mL. For the biofilm assay, the isolated compounds and combinations at 1 min and 6 h showed significantly different results from the controls (p < 0.05). Furthermore, the HET-CAM results demonstrated the absence of irritability. Based on these premises, the antifungal and antioxidant actions, and absence of irritability were proven. Moreover, this work presents a natural antifungal of interest to the pharmaceutical industry. [ABSTRACT FROM AUTHOR]

This article undertakes a theoretical post-Keynesian analysis to explore the relationship between inflation, unemployment, and inequality. Firstly, we show the compatibility of the inequality-augmented Phillips curve, which first appeared in Rolim, Carvalho, and Lang (2023), with the post-Keynesian macroeconomic theory. The curve combines the Phillips curve, which relates unemployment and inflation and can be derived from the conflicting-claims inflation model, with the positive relation between unemployment and inequality due to the heterogeneous impact of unemployment on workers. The unemployment rate thus connects the inflation rate to income inequality in a three-dimensional relationship described by the inequality-augmented Phillips curve, which indicates a possible trade-off between low inflation and low inequality. Secondly, we consider the profits inflation case: when inflation is simultaneous with markup increases. Increases in the ex-ante markup rate shift the curve upwards, thus increasing the inflation rate and inequality. In this context, if monetary policy aims to control inflation by increasing unemployment, it will operate along the inequality-augmented Phillips curve and will further increase inequality. [ABSTRACT FROM AUTHOR]

Copyright of OKARA: Geografia em Debate is the property of OKARA Geografia em Debate and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Lichen-feeding termites occupy a distinctive ecological niche. This feeding behavior underscores a complex interplay between the termites' digestive abilities and the biochemical properties of lichens, known for their resilience and production of secondary metabolites. Understanding the dietary preferences and digestive mechanisms of these termites offers insights into their ecological roles and the evolutionary adaptations that enable them to exploit such a specialized food source. We conducted experiments with Constrictotermes cyphergaster, feeding it with different combinations of its natural food sources: wood bark and lichen from host trees. Gut microbial communities were analyzed through 16S rRNA sequencing and shotgun metagenomics. Our results revealed that a diet containing lichens induces a shift in microbiota composition and increases the abundance of genes encoding an AA3 enzyme with a role in lignin digestion. This study emphasizes the potential role of lichens in enhancing the digestive capabilities of termites, highlighting the intricate relationships between diet, gut microbiota, and enzymatic activity in Termitidae. [ABSTRACT FROM AUTHOR]

Acerola fruit has great nutritional and economic relevance; however, its rapid degradation hinders commercialization. The use of coatings reduces post-harvest biochemical modifications and provides physical and biological protection for vegetables such as acerola. This study developed and characterized an edible coating made from pearl pineapple peel flour (PPPF) and yam starch (YS) to preserve the quality standards of acerola fruits during storage at room temperature and under refrigeration. The edible coating, composed of 4 g of PPPF, 3 g of starch, and 10% glycerol, presented excellent moisture content (11%), light tone (L* 83.68), and opacity (45%), resistance to traction of 27.77 Mpa, elastic modulus of 1.38 Mpa, and elongation percentage of 20%. The total phenolic content of the coating was 278.68 ± 0.45 mg GAE/g and the antioxidant activity by DPPH was 28.85 ± 0.27%. The quality parameters of acerolas were evaluated with three treatments: T1—uncoated fruits; T2—fruits coated with 1% glycerol; and T3—fruits coated with PPPF-YS. The T3 treatment reduced the weight loss of stored acerolas, maintaining the light and bright color of the fruits, and delayed the decrease in soluble solids, especially in refrigerated fruits. Therefore, edible coatings based on pineapple flour and yam starch are effective technologies for controlling the physical and physicochemical parameters of acerolas during storage, benefiting the post-harvest quality of this fruit. [ABSTRACT FROM AUTHOR]

Heavy mineral deposits occur in several coastal areas of the world, formed over a long period due to variations in mean sea level, wave action, and winds. These are the main sources of ilmenite (FeTiO3), which in turn is the source of more than 80% of the TiO2 produced and applied in various industries, most recently in nanotechnology. The present study mapped heavy mineral deposits on the coast of Rio Grande do Sul in southern Brazil using integrated proximal and orbital thermal infrared (TIR) remote sensing techniques. Mineral groups, such as oxides and silicates, have spectral features in the TIR wavelengths. Using laboratory spectroscopy at TIR using Nicolet 6700 Thermo Scientific Spectrometer, we measured the spectral signature of the local sample of heavy minerals (between 8 and 14 μm) and identified a diagnostic spectral feature at 10.75 μm. The signature was resampled to be compatible with the Advanced Spaceborne Thermal Emission Radiometer (ASTER) sensor bandwidth values and used as a reference endmember for the Spectral Angle Mapper (SAM) and Linear Spectral Unmixing (LSU) digital image classification algorithms. Thus, we identified the presence of the reference endmember (heavy minerals) in the pixels of the ASTER scene. In pixels classified by SAM as the presence of heavy minerals, LSU was applied to estimate the surface concentration within the pixel. The results showed a concentration of up to 20% of heavy minerals, with the highest concentration on the beach and dune fields. Opaque minerals such as ilmenite do not have spectral reflectance features in visible, near-infrared, and short-wave infrared, which makes their identification by remote sensing difficult. The present study showed that the integration of proximal and orbital as well as hyperspectral and multispectral thermal data can be considered as an alternative for detecting and mapping heavy minerals in coastal areas. [ABSTRACT FROM AUTHOR]

Knowing the number of workable days (NWD) with agricultural machinery during a crop is crucial to mitigate structural soil degradation in conditions of insufficient moisture. Although soil moisture is the most important, field planning often only involves precipitation. This study aimed to quantify NWD for the main sugarcane producing municipalities in Brazil across different seasons, considering the water balance. Two criteria were adopted to determine NWD: one includes days suitable for agricultural activities with daily precipitation less than 5 mm and soil water content between 40 and 90% of available water capacity, while the other only integrates precipitation (< 5 mm). Thirty years of daily climate data were collected for Brazilian locations to calculate the water balance. Cluster analysis was applied to group similar localities based on meteorological and water balance components. The study began with a statistical analysis of variability between groups and intragroup of meteorological and water balance elements. Subsequently, NWD maps were created for the past 30 years (characterization) and the past 10 years (planning), both for dry and rainy periods. A comparative analysis of the two criteria to account NWD was conducted. Over the last decade, significant drought trends led to an approximately 10-day increase in NWD nationwide during both dry and rainy seasons. The NWD criteria choice significantly impacted results, depending on the region of the country, reaching differences of up to 60 days within a total period of 90 days. The criterion considering soil water content tended to underestimate workable days but closely aligned with agricultural reality. [ABSTRACT FROM AUTHOR]

The water deficit resulting from climate variations limits the profitability and sustainability of sugarcane fields, making water supply through irrigation necessary to sustain the potential production of sugarcane. However, the water used for irrigation purposes must be properly managed, ensuring the conservation of water resources and the reduction of costs with the use of inputs and energy. Pulsed drip irrigation aims to support irrigation management, improving the efficient use of water and mitigating the deleterious effects of water deficit. This study aims to evaluate the growth, productivity, and industrial yield of sugarcane cultivated under continuous and pulsed drip irrigation. A field experiment was conducted at the Experimental Sugarcane Station of Carpina, in Carpina in the State of Pernambuco, Northeast Brazil, from December 2020 to December 2021. The experimental arrangement was randomized blocks in a 2 x 5 factorial design, with two types of irrigation application (pulsed and continuous) and five irrigation levels (40, 60, 80, 100, and 120% of crop evapotranspiration – ETc), with four replications. Pulsed drip irrigation increased the yield of stalks (9%) and sugar (21%) in the sugarcane crop and ethanol (17%) derived from sugar in the juice. Pulsed drip irrigation, when compared to continuous irrigation, improved the performance of sugarcane, providing a reduction in water consumption and increasing growth, stalk yield, sugar and predicted ethanol yield. Thus, based on this study, pulse irrigation is an efficient approach to irrigation management, contributing to the stability of sugarcane production while conserving water relative to continuous irrigation. [ABSTRACT FROM AUTHOR]

Nanoparticles represent an innovative class of drug delivery systems that have gained increasing interest in nanotechnology applied to medicine. This study focused on the development of two Polyglycerol/PolyCaprolactone Nanocopolymers to be able to carry pharmaceuticals. The copolymers were characterized by FTIR, NMR, TG, DSC, MALDI, SEM, and DLS techniques. Two monomer initiators (glycerol and 1,1,1-tris(hydroxymethyl)propane) have been used, and the polymerization was obtained by anionic ring-opening polymerization of the glycerol carbonate, with CO2 liberation leading to a branched polyether. The hyperbranched polymer was employed as a macroinitiator to initiate the ring-opening polymerization of ε-caprolactone, resulting in the multiarm star copolymers. The structures for the nanocopolymers were proposed based on nuclear magnetic resonance results. Hemolytic studies revealed that the copolymers do not have hemolytic activity. The copolymers were tested for safety against human cells and toxicity in cancer cells. The tests indicated that they are safe for in vivo applications and do not have anti-cancer efficiency, corroborating their purpose as a polymeric support for drug delivery. [ABSTRACT FROM AUTHOR]

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Purpose: To describe the Single Leg Bridge Test (SLBT) of women's soccer professional athletes. Design and settings: Cross-sectional study. On-field assessment. Methods: Professional athletes from four elite women's soccer teams enrolled in the First Division Brazilian Women's Soccer Championship. Main outcome measures: SLBT score and the limb symmetry index (LSI). Results: One hundred twenty-one athletes (two hundred forty-two limbs) took part in this study. They had a SLBT score of 33 ± 12 repetitions (95% CI 31 to 34 repetitions), ranging from 11 to 70 repetitions. No significant difference was found between dominant and non-dominant limbs (p = 0.816). Athletes presented an LSI of 104 ± 20% (95% CI 100.2% to 107.4%). SLBT score had no significant correlation with athletes' age, while a poor negative correlation (r < 0.5) was found between SLBT score and athletes' body mass and height. Conclusion: This pioneering study identified an average SLBT score of 33 repetitions for women's soccer professional athletes. Despite a diverse range of performance on the SLBT, limb dominance, age, body mass, or height do not strongly correlate with the score. [ABSTRACT FROM AUTHOR]