Search

Dietary restriction (DR) and hypoxia (low oxygen) extend lifespan in Caenorhabditis elegans through the induction of a convergent downstream longevity gene, fmo-2. Flavin-containing monooxygenases (FMOs) are highly conserved xenobiotic-metabolizing enzymes with a clear role in promoting longevity in nematodes and a plausible similar role in mammals. This makes them an attractive potential target of small molecule drugs to stimulate the health-promoting effects of longevity pathways. Here, we utilize an fmo-2 fluorescent transcriptional reporter in C. elegans to screen a set of 80 compounds previously shown to improve stress resistance in mouse fibroblasts. Our data show that 19 compounds significantly induce fmo-2, and 10 of the compounds induce fmo-2 more than twofold. Interestingly, 9 of the 10 high fmo-2 inducers also extend lifespan in C. elegans. Two of these drugs, mitochondrial respiration chain complex inhibitors, interact with the hypoxia pathway to induce fmo-2, whereas two dopamine receptor type 2 (DRD2) antagonists interact with the DR pathway to induce fmo-2, indicating that dopamine signaling is involved in DR-mediated fmo-2 induction. Together, our data identify nine drugs that each (1) increase stress resistance in mouse fibroblasts, (2) induce fmo-2 in C. elegans, and (3) extend nematode lifespan, some through known longevity pathways. These results define fmo-2 induction as a viable approach to identifying and understanding mechanisms of putative longevity compounds. [ABSTRACT FROM AUTHOR]

Objectives: Emergency ultrasound (EUS) is a critical component of emergency medicine (EM) resident education. Currently, there is no consensus list of competencies for EUS training, and graduating residents have varying levels of skill and comfort. The objective of this study was to define a widely accepted comprehensive list of EUS competencies for graduating EM residents through a modified Delphi method. Methods: We developed a list of EUS applications through a comprehensive literature search, the American College of Emergency Physicians list of core EUS benchmarks, and the Council of Emergency Medicine Residency-Academy of Emergency Ultrasound consensus document. We assembled a multi-institutional expert panel including 15 faculty members from diverse practice environments and geographical regions. The panel voted on the list of competencies through two rounds of a modified Delphi process using a modified Likert scale (1 = not at all important, 5 = very important) to determine levels of agreement for each application--with revisions occurring between the two rounds. High agreement for consensus was set at >80%. Results: Fifteen of 15 panelists completed the first-round survey (100%) that included 359 topics related to EUS. After the first round, 195 applications achieved high agreement, four applications achieved medium agreement, and 164 applications achieved low agreement. After the discussion, we removed three questions and added 13 questions. Fifteen of 15 panelists completed the second round of the survey (100%) with 209 of the 369 applications achieving consensus. Conclusion: Our final list represents expert opinion on EUS competencies for graduating EM residents. We hope to use this consensus list to implement a more consistent EUS curriculum for graduating EM residents and to standardize EUS training across EM residency programs. [ABSTRACT FROM AUTHOR]

Interprofessional experiences during medical school are often delivered during pre-clinical years, but less is known about the value of clinical students. Our institution implemented a specialty-specific interprofessiona curriculum during Residency Preparation Courses (RPCs) for senior students including didactics, clinical experiences, and a simulated paging curriculum. Our aim was to determine whether this intervention improved perceptions of interprofesiona roles. We distributed anonymous surveys before (pre-survey) and after (post-survey, collected within 2 weeks of course completion) the RPC to 90 students with questions related to interprofessional roles using a 5-point scale (1 = strongly disagree, 5 = strongly agree). Three months after the start of residency, we sent follow-up surveys inquiring about the usefulness of RPC components (1 = not at all useful, 5 = extremely useful). Response rates were 84.4% pre-survey, 63.3% post-survey, and 41.1% follow-up survey. Post-surveys indicated improvement in self-reported ability in all domains: understanding one's contributions to interprofessional teams (3.9 to 4.4, p <.0001), understanding other team members' contributions (3.9 to 4.4, p <.0001), learning from interprofessional team members (4.2 to 4.6, p =.0002), accounting for interprofessional perspectives (4.2 to 4.6, p <.0001), and co-developing effective care plans (3.9 to 4.4, p <.0001). Follow-up surveys rated clinical experiences as slightly-to-moderately useful (2.3 ± 1.0) and paging curriculum very-to-extremely useful (4.3 ± 1.0). This study demonstrates the value of interprofessional education for advanced students. [ABSTRACT FROM AUTHOR]

This article investigates how fashion and nationalism were expressed through two iconic dress styles worn by women, the qipao in Taiwan and the terno in the Philippines in the post-WWII era. We consider the positioning of women's bodies in the nation-building project and how sartorial practices reflected expectations around gendered performance in the public and private spheres. Both countries emerged from domination by major powers—Japan and the US—in the post-war era and ruling elites were keen to project an image of nation that was distinctively Asian and modern, while the first ladies of both nations championed their respective styles of national dress. In the Philippines, the terno was a fusion garment adapted over time that reflected the nation's earlier cultural links with Spain, whereas in Taiwan the qipao marked women's bodies as Chinese in the public sphere as Chinese nationalists consolidated their political control over the country. We argue that the relative success and longevity of the terno in the Philippines is due to a lengthy, organic process of internal cultural authentication prior to its take-up by former First Lady Imelda Marcos, as opposed to the top-down imposition of the qipao on Taiwanese women's bodies. [ABSTRACT FROM AUTHOR]

Prior reviews investigated medical education developments in response to COVID-19, identifying the pivot to remote learning as a key area for future investigation. This review synthesized online learning developments aimed at replacing previously face-to-face 'classroom' activities for postgraduate learners. Four online databases (CINAHL, Embase, PsychINFO, and PubMed) and MedEdPublish were searched through 21 December 2020. Two authors independently screened titles, abstracts and full texts, performed data extraction, and assessed risk of bias. The PICRAT technology integration framework was applied to examine how teachers integrated and learners engaged with technology. A descriptive synthesis and outcomes were reported. A thematic analysis explored limitations and lessons learned. Fifty-one publications were included. Fifteen collaborations were featured, including international partnerships and national networks of program directors. Thirty-nine developments described pivots of existing educational offerings online and twelve described new developments. Most interventions included synchronous activities (n Fif5). Virtual engagement was promoted through chat, virtual whiteboards, polling, and breakouts. Teacher's use of technology largely replaced traditional practice. Student engagement was largely interactive. Underpinning theories were uncommon. Quality assessments revealed moderate to high risk of bias in study reporting and methodology. Forty-five developments assessed reaction; twenty-five attitudes, knowledge or skills; and two behavior. Outcomes were markedly positive. Eighteen publications reported social media or other outcomes, including reach, engagement, and participation. Limitations included loss of social interactions, lack of hands-on experiences, challenges with technology and issues with study design. Lessons learned highlighted the flexibility of online learning, as well as practical advice to optimize the online environment. This review offers guidance to educators attempting to optimize learning in a post-pandemic world. Future developments would benefit from leveraging collaborations, considering technology integration frameworks, underpinning developments with theory, exploring additional outcomes, and designing and reporting developments in a manner that supports replication. [ABSTRACT FROM AUTHOR]

A constitutive model for niobium with the effect of dynamic strain aging is proposed. The crystal structure of metals hugely influences the dynamic strain aging phenomenon and causes considerable alterations in the material's macroscopic mechanical responses. Dynamic strain aging needs to be accounted for in a constitutive model to obtain accurate predictions of material's thermo-mechanical behaviors during deformation. The proposed constitutive model attempts to describe the material's flow stress responses during deformation by separating the flow stress contributions into the athermal component, thermal component, and dynamic strain aging component. Two different mathematical equations are proposed to model the dynamic strain aging component. The proposed model attempts to describe the mechanical response of niobium for a wide range of strain rates: from quasi-static loading ( ε ˙ = 0.001 s - 1 ) to dynamic loading ( ε ˙ = 3300 s - 1 ) across the temperature ranges 77 K–800 K. [ABSTRACT FROM AUTHOR]

The novel coronavirus disease was declared a pandemic in March 2020, which necessitated adaptations to medical education. This systematic review synthesises published reports of medical educational developments and innovations that pivot to online learning from workplace-based clinical learning in response to the pandemic. The objectives were to synthesise what adaptations/innovation were implemented (description), their impact (justification), and 'how' and 'why' these were selected (explanation and rationale). The authors systematically searched four online databases up to December 21, 2020. Two authors independently screened titles, abstracts and full-texts, performed data extraction, and assessed the risk of bias. Our findings are reported in alignment with the STORIES (STructured apprOach to the Reporting in healthcare education of Evidence Synthesis) statement and BEME guidance. Fifty-five articles were included. Most were from North America (n = 40), and nearly 70% focused on undergraduate medical education (UGME). Key developments were rapid shifts from workplace-based learning to virtual spaces, including online electives, telesimulation, telehealth, radiology, and pathology image repositories, live-streaming or pre-recorded videos of surgical procedures, stepping up of medical students to support clinical services, remote adaptations for clinical visits, multidisciplinary team meetings and ward rounds. Challenges included lack of personal interactions, lack of standardised telemedicine curricula and need for faculty time, technical resources, and devices. Assessment of risk of bias revealed poor reporting of underpinning theory, resources, setting, educational methods, and content. This review highlights the response of medical educators in deploying adaptations and innovations. Whilst few are new, the complexity, concomitant use of multiple methods and the specific pragmatic choices of educators offers useful insight to clinical teachers who wish to deploy such methods within their own practice. Future works that offer more specific details to allow replication and understanding of conceptual underpinnings are likely to justify an update to this review. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic spurred an abrupt transition away from in-person educational activities. This systematic review investigated the pivot to online learning for nonclinical undergraduate medical education (UGME) activities and explored descriptions of educational offerings deployed, their impact, and lessons learned. The authors systematically searched four online databases and conducted a manual electronic search of MedEdPublish up to December 21, 2020. Two authors independently screened titles, abstracts and full texts, performed data extraction and assessed risk of bias. A third author resolved discrepancies. Findings were reported in accordance with the STORIES (STructured apprOach to the Reporting in healthcare education of Evidence Synthesis) statement and BEME guidance. Fifty-six articles were included. The majority (n = 41) described the rapid transition of existing offerings to online formats, whereas fewer (n = 15) described novel activities. The majority (n = 27) included a combination of synchronous and asynchronous components. Didactics (n = 40) and small groups (n = 26) were the most common instructional methods. Teachers largely integrated technology to replace and amplify rather than transform learning, though learner engagement was often interactive. Thematic analysis revealed unique challenges of online learning, as well as exemplary practices. The quality of study designs and reporting was modest, with underpinning theory at highest risk of bias. Virtually all studies (n = 54) assessed reaction/satisfaction, fewer than half (n = 23) assessed changes in attitudes, knowledge or skills, and none assessed behavioral, organizational or patient outcomes. UGME educators successfully transitioned face-to-face instructional methods online and implemented novel solutions during the COVID-19 pandemic. Although technology's potential to transform teaching is not yet fully realized, the use of synchronous and asynchronous formats encouraged virtual engagement, while offering flexible, self-directed learning. As we transition from emergency remote learning to a post-pandemic world, educators must underpin new developments with theory, report additional outcomes and provide details that support replication. [ABSTRACT FROM AUTHOR]

COVID-19 has fundamentally altered how education is delivered. Gordon et al. previously conducted a review of medical education developments in response to COVID-19; however, the field has rapidly evolved in the ensuing months. This scoping review aims to map the extent, range and nature of subsequent developments, summarizing the expanding evidence base and identifying areas for future research. The authors followed the five stages of a scoping review outlined by Arskey and O'Malley. Four online databases and MedEdPublish were searched. Two authors independently screened titles, abstracts and full texts. Included articles described developments in medical education deployed in response to COVID-19 and reported outcomes. Data extraction was completed by two authors and synthesized into a variety of maps and charts. One hundred twenty-seven articles were included: 104 were from North America, Asia and Europe; 51 were undergraduate, 41 graduate, 22 continuing medical education, and 13 mixed; 35 were implemented by universities, 75 by academic hospitals, and 17 by organizations or collaborations. The focus of developments included pivoting to online learning (n = 58), simulation (n = 24), assessment (n = 11), well-being (n = 8), telehealth (n = 5), clinical service reconfigurations (n = 4), interviews (n = 4), service provision (n = 2), faculty development (n = 2) and other (n = 9). The most common Kirkpatrick outcome reported was Level 1, however, a number of studies reported 2a or 2b. A few described Levels 3, 4a, 4b or other outcomes (e.g. quality improvement). This scoping review mapped the available literature on developments in medical education in response to COVID-19, summarizing developments and outcomes to serve as a guide for future work. The review highlighted areas of relative strength, as well as several gaps. Numerous articles have been written about remote learning and simulation and these areas are ripe for full systematic reviews. Telehealth, interviews and faculty development were lacking and need urgent attention. [ABSTRACT FROM AUTHOR]

Over the last decade, medical student residency applicants have shown a substantial increase in the number of interviews attended, which is associated with a significant increase in travel. The carbon footprint associated with residency interviews has not been well documented prior to this investigation, and is a critical issue related to climate health. The purpose of this study is to document the carbon footprint associated with travel to residency interviews of the applicants from a single institution. Graduating medical students from the University of Michigan Medical School were surveyed in 2020 to gather information regarding travel related to residency interviews. A validated carbon emissions calculator was used to determine the associated carbon footprint. Response rate was 103 of 174 (59%). Average interviews per student across all specialties was 14.39 interviews per student. The overall class average for total carbon footprint per student was calculated as 3.07 metric tons CO2, making the class average carbon footprint per interview 0.21 metric tons CO2. If we extrapolate the results of our study to all residents, the resulting CO2 emissions approach 51 665 metric tons CO2 per year, which is equivalent to the amount of CO2 produced by 11 162 passenger cars in 1 year. Medical education leaders could help reduce the carbon footprint by encouraging a reduction in number of in-person interviews attended by applicants. [ABSTRACT FROM AUTHOR]

Introduction: Scholarship and academic networking are essential for promotion and productivity. To develop education scholarship, the Council of Emergency Medicine Directors (CORD) and Clerkship Directors of Emergency Medicine (CDEM) created an annual Special Issue in Educational Research and Practice of the Western Journal of Emergency Medicine. The objective of this study was to evaluate the network created by the special Issue, and explore changes within the network over time. Methods: Researchers used bibliometric data from Web of Science to create a social network analysis of institutions publishing in the first four years of the special issue using UCINET software. We analyzed whole-network and node-level metrics to describe variations and changes within the network. Results: One hundred and three (56%) Accreditation Council for Graduate Medical Educationaccredited emergency medicine programs were involved in 136 articles. The majority of institutions published in one or two issues. Nearly 25% published in three or four issues. The network analysis demonstrated that the mean number of connections per institution increased over the four years (mean of 5.34; standard deviation [SD] 1.27). Mean degree centralization was low at 0.28 (SD 0.05). Network density was low (mean of 0.09; SD 0.01) with little change across four issues. Five institutions scored consistently high in betweenness centrality, demonstrating a role as connectors between institutions within the network and the potential to connect new members to the network. Conclusion: Network-wide metrics describe a consistently low-density network with decreasing degree centralization over four years. A small number of institutions within the network were persistently key players in the network. These data indicate that, aside from core institutions that publish together, the network is not widely connected. There is evidence that new institutions are coming into the network, but they are not necessarily connected to the core publishing groups. There may be opportunities to intentionally increase connections across the network and create new connections between traditionally high-performing institutions and newer members of the network. Through informal discussions with authors from high-performing institutions, there are specific behaviors that departments may use to promote education scholarship and forge these new connections. [ABSTRACT FROM AUTHOR]

Introduction: The coronavirus disease 2019 (COVID-19) pandemic presents unique challenges to frontline healthcare workers. In order to safely care for patients new processes, such as a plan for the airway management of a patient with COVID-19, must be implemented and disseminated in a rapid fashion. The use of in-situ simulation has been used to assist in latent problem identification as part of a Plan-Do-Study-Act cycle. Additionally, simulation is an effective means for training teams to perform high-risk procedures before engaging in the actual procedure. This educational advance seeks to use and study in-situ simulation as a means to rapidly implement a process for airway management in patients with COVID-19. Methods: Using an airway algorithm developed by the authors, we designed an in-situ simulation scenario to train physicians, nurses, and respiratory therapists in best practices for airway management of patients with COVID-19. Physician participants were surveyed using a five-point Likert scale with regard to their comfort level with various aspects of the airway algorithm both before and after the simulation in a retrospective fashion. Additionally, we obtained feedback from all participants and used it to refine the airway algorithm. Results: Over a two-week period, 93 physicians participated in the simulation. We received 81 responses to the survey (87%), which showed that the average level of comfort with personal protective equipment procedures increased significantly from 2.94 (95% confidence interval, 2.71-3.17) to 4.36 (4.24-4.48), a difference of 1.42 (1.20-1.63, p < 0.001). There was a significant increase in average comfort level in understanding the physician role with scores increasing from 3.51 (3.26-3.77) to 4.55 (2.71-3.17), a difference of 1.04 (0.82-1.25, p < 0.001). There was also increased comfort in performing procedural tasks such as intubation, from 3.08 (2.80-3.35) to 4.38 (4.23-4.52) after the simulation, a difference of 1.30 points (1.06-1.54, p < 0.001). Feedback from the participants also led to refinement of the airway algorithm. Conclusion: We successfully implemented a new airway management guideline for patients with suspected COVID-19. In-situ simulation is an essential tool for both dissemination and onboarding, as well as process improvement, in the context of an epidemic or pandemic. [ABSTRACT FROM AUTHOR]

The Peñafrancia Festival in the Bicol region of the Philippines has the distinction of being the largest Marian festival in Asia, with a focus on the power of Mother Mary to intercede on behalf of the faithful. It is also known for its 'fluvial procession' down a narrow river on the final Sunday when a sacred icon of Mary leaves Naga City's main cathedral and returns to her year-round home in a nearby basilica. Connected with the religious festival are a range of performance practices that mobilise the youth, notably theatricalised street dance presentations that mirror the religious practices undertaken by the town's adults, as well as precision marching band and baton twirling presentations in the city's main public square. These constitute the most widely practised forms of competitive, community based performance engaged in by the region's youth. This article examines these two key spin-off practices associated with the festival, and considers how in their design and execution they serve to define the individual's place in relation to others, and in so doing, create coherent communities through shared, embodied practices of performance. [ABSTRACT FROM AUTHOR]

Introduction: Forming effective networks is important for personal productivity and career development. Although critical for success, these networks are not well understood. The objective of this study was to usze a social network analysis tool to demonstrate the growth of institutional publication networks for education researchers and show how a single institution has expanded its publication network over time. Methods: Publications from a single institution's medical education research group (MERG) were pulled since its inception in 2010 to 2019 using Web of Science to collect publication information. Using VOSViewer software, we formed and plotted a network sociogram comparing the first five years to the most recent 4.25 years to compare the institutions of authors from peer reviewed manuscripts published by this group. Results: We found 104 peer-reviewed research articles, editorials, abstracts, and reviews for the MERG authors between 2010 and 2019 involving 134 unique institutions. During 2010-2014, there were 26 publications involving 56 institutions. From 2015- 2019, there were 78 publications involving 116 unique institutions. Conclusion: This brief report correlates successful research productivity in medical education with the presence of increased inter-institutional collaborations as demonstrated by network sociograms. Programs to intentionally expand collaborative networks may prove to be an important element of facilitating successful careers in medical education scholarship. [ABSTRACT FROM AUTHOR]

Introduction: Leading change effectively is critical to advancing medical education. Residency didactics often require change in order to meet stakeholder's needs. Kotter's change management model (KCMM) is an 8-step method for implementing change that can be applied to educational initiatives. This innovation improved an emergency medicine residency didactics curriculum through application of KCMM. Methods: An initiative to improve residency didactics curriculum was titled the "Didactics Revolution" and implemented according to KCMM: establish a sense of urgency, form a powerful guiding coalition, create a vision, communicate the vision, empower others to act on the vision, plan for and create short-term wins, consolidate improvements and produce still more change, and institutionalize new approaches. Data from the Annual Program Review was utilized to assess the impact of the KCMM strategy. Results: The percentage of residents who agreed or strongly agreed that lectures provide a valuable learning experience increased from 39.1% in the year prior to 88.0% in the year during the implementation (p < .001), and remained relatively high at 73.5% in the year following. The percentage of residents who agreed or strongly agreed that they felt well-prepared for the written boards increased from 60.9% in the year prior to 92.0% in the year during the implementation (p = .01) and remained high at 73.5% in the year following. Conclusion: Residency didactics can be improved through the use of KCMM, a change management model originally developed in the corporate context. [ABSTRACT FROM AUTHOR]

Coastal upwelling is known for inducing nearshore primary production, which can be advected to the offshore environment through offshore Ekman transport. However, this nearshore−offshore phytoplankton link has been less characterized at the community level. This study focuses on two shelf and slope sites off Oregon during years of 2013−2017 to examine the shelf−slope covariations in diatom and dinoflagellate abundance and community structure at seasonal and annual timescales. In general, the temporal changes of diatom and dinoflagellate abundance were coherent between shelf and slope. However, some differences were also noticeable. For example, diatom and dinoflagellate bloom magnitudes were higher in 2017 and 2014 on the shelf, but were higher in 2014−2016 at the slope. Diatom abundance had a stronger shelf−slope correlation than dinoflagellate correlation particularly in spring. The community structure was significantly correlated between shelf and slope during the annual upwelling period and in spring season. Ekman transport and nutrients played a significant role in shaping the diatom abundance and community structure temporal patterns at the slope. This shelf−slope correlation study infers that the benefits of nearshore upwelling blooms to the offshore food chains are season dependent and under high interannual variability. [ABSTRACT FROM AUTHOR]

Background: Relatively little is understood about which factors influence students’ choice of specialty and when learners ultimately make this decision. Objective: The objective is to understand how experiences of medical students relate to the timing of selection of Emergency Medicine (EM) as a specialty. Of specific interest were factors such as how earlier and more positive specialty exposure may impact the decision-making process of medical students. Methods: A cross-sectional survey study of EM bound 4th year US medical students (MD and DO) was performed exploring when and why students choose EM as their specialty. An electronic survey was distributed in March 2015 to all medical students who applied to an EM residency at 4 programs representing different geographical regions. Descriptive analyses and multinomial logistic regressions were performed. Results: 793/1372 (58%) responded. Over half had EM experience prior to medical school. When students selected EM varied: 13.9% prior to, 50.4% during, and 35.7% after their M3 year. Early exposure, presence of an EM residency program, previous employment in the ED, experience as a pre-hospital provider, and completion of an M3 EM clerkship were associated with earlier selection. Delayed exposure to EM was associated with later selection of EM. Conclusions: Early exposure and prior life experiences were associated with choosing EM earlier in medical school. The third year was identified as the most common time for definitively choosing the specialty. [ABSTRACT FROM AUTHOR]

Abstract: Climate change has exacerbated the occurrence of large‐scale sea surface temperature anomalies, or marine heatwaves (MHWs)—extreme phenomena often associated with mass mortality events of marine organisms. Using a combination of citizen science and federal data sets, we investigated the causal mechanisms of the 2014/2015 die‐off of Cassin's Auklets (Ptychoramphus aleuticus), a small zooplanktivorous seabird, during the NE Pacific MHW of 2013–2015. Carcass deposition followed an effective reduction in the energy content of mesozooplankton, coincident with the loss of cold‐water foraging habitat caused by the intrusion of the NE Pacific MHW into the nearshore environment. Models examining interannual variability in effort‐controlled carcass abundance (2001–2014) identified the biomass of lipid‐poor zooplankton as the dominant predictor of increased carcass abundance. In 2014, Cassin's Auklets dispersing from colonies in British Columbia likely congregated into a nearshore band of cooler upwelled water and ultimately died from starvation following the shift in zooplankton composition associated with onshore transport of the NE Pacific MHW. For Cassin's Auklets, already in decline due to ocean warming, large‐scale and persistent MHWs might represent a global population precipice. [ABSTRACT FROM AUTHOR]

During 2014 exceptionally warm water temperatures developed across a wide area off the California coast and within San Francisco Bay (SFB) and persisted into 2016. Observations and numerical model output are used to document this warming and determine its origins. The coastal warming was mostly confined to the upper 100 m of the ocean and was manifested strongly in the two leading modes of upper ocean (0-100 m) temperature variability in the extratropical eastern Pacific. Observations suggest that the coastal warming in 2014 propagated into nearshore regions from the west while later indicating a warming influence that propagated from south to north into the region associated with the 2015-2016 El Niño event. An analysis of the upper ocean (0-100 m) heat budget in a Regional Ocean Modeling System (ROMS) simulation confirmed this scenario. The results from a set of sensitivity runs with the model in which the lateral boundary conditions varied supported the conclusions drawn from the heat budget analysis. Concerning the warming in the SFB, an examination of the observations and the heat budget in an unstructured-grid numerical model simulation suggested that the warming during the second half of 2014 and early 2016 originated in the adjacent California coastal ocean and propagated through the Golden Gate into the Bay. The finding that the coastal and Bay warming are due to the relatively slow propagation of signals from remote sources raises the possibility that such warming events may be predictable many months or even several seasons in advance. [ABSTRACT FROM AUTHOR]

A warm anomaly in the upper ocean, colloquially named 'the Blob,' appeared in the Gulf of Alaska during the calm winter of 2013-2014, spread across the northern North Pacific (NP) Ocean, and shifted eastward and onto the Oregon shelf. At least 14 species of copepods occurred which had never been observed in shelf/slope waters off Oregon, some of which are known to have NP Gyre affinities, indicating that the source waters of the coastal 'Blob' were likely of both offshore (from the west) and subtropical/tropical origin. The anomalously warm conditions were reduced during strong upwelling in spring 2015 but returned when upwelling weakened in July 2015 and transitioned to downwelling in fall 2015. The extended period of warm conditions resulted in prolonged effects on the ecosystem off central Oregon, lasting at least through 2016. Impacts to the lower trophic levels were unprecedented and include a novel plankton community composition resulting from increased copepod, diatom, and dinoflagellate species richness and increased abundance of dinoflagellates. Additionally, the multiyear warm anomalies were associated with reduced biomass of copepods and euphausiids, high abundance of larvaceans and doliolids (indictors of oligotrophic ocean conditions), and a toxic diatom bloom ( Pseudo-nitzschia) throughout the California Current in 2015, thereby changing the composition of the food web that is relied upon by many commercially and ecologically important species. [ABSTRACT FROM AUTHOR]

We investigated the nucleic acid ratio (RNA/DNA) as a proxy for starvation in copepods collected from coastal and pelagic sites across the North Pacific Ocean. While RNA/DNA ratios were variable among copepod species and their life stages, lower ratios were found for the copepods collected from the Kuroshio region compared to ones from the western subarctic site of the North Pacific Ocean. Log-transformed RNA/DNA ratios showed a negative correlation to log-transformed mean temperature in the sampling layer and a positive correlation to log-transformed chlorophyll a concentrations. Copepod incubation experiments demonstrated that RNA/DNA ratios significantly declined after exposure to starvation and the decline was greater for the copepods collected from the subtropical sites compared with those from the subarctic. However, no significant decline was found for some species and stages accumulating lipids. These findings suggest that copepod RNA/DNA ratios are associated with food availability but are not sensitive to starvation for some copepods accumulating lipids. [ABSTRACT FROM AUTHOR]

Domoic acid is a potent neurotoxin produced by certain marine microalgae that can accumulate in the foodweb, posing a health threat to human seafood consumers and wildlife in coastal regions worldwide. Evidence of climatic regulation of domoic acid in shellfish over the past 20 y in the Northern California Current regime is shown. The timing of elevated domoic acid is strongly related to warm phases of the Pacific Decadal Oscillation and the Oceanic Niño Index, an indicator of El Niño events. Ocean conditions in the northeast Pacific that are associated with warm phases of these indices, including changes in prevailing currents and advection of anomalously warm water masses onto the continental shelf, are hypothesized to contribute to increases in this toxin. We present an applied domoic acid risk assessment model for the US West Coast based on combined climatic and local variables. Evidence of regional- to basin-scale controls on domoic acid has not previously been presented. Our findings have implications in coastal zones worldwide that are affected by this toxin and are particularly relevant given the increased frequency of anomalously warm ocean conditions. [ABSTRACT FROM AUTHOR]

In spring/summer 2015, a toxic bloom by the diatom Pseudo-nitzschia (PN) occurred along the west coast of the United States which led to closures of the harvest of razor clams and Dungeness crabs. Twice monthly observations of temperature, salinity, nutrients, chlorophyll and phytoplankton species composition allowed us to track oceanographic conditions preceding and during the development of the bloom. PN cells were first detected during late winter 2015. A PN bloom was initiated following the onset of coastal upwelling in mid-April; subsequent peaks in May and June were sustained by episodic upwelling events and reached magnitudes of 105 cells/L and 106 cells/L, 40% and 90% of the total diatom abundance, respectively. The bloom temporarily crashed in July due to a lack of upwelling, but PN cells increased again in August due to a resumption of upwelling, albeit with lower magnitude. Macronutrient conditions prior to this bloom likely played a critical role in triggering the bloom and its toxicity (particularly silicic acid limitation stress). Nutrient stress preceding the toxic bloom was related to two oceanographic events: an anomalously warm and thick water mass that occupied the northern North Pacific from September 2014 through 2015 leading to a highly-stratified water column, and the drawdown of nitrate and silicic acid during an unusually intense winter phytoplankton bloom in February and early March 2015. [ABSTRACT FROM AUTHOR]

Introduction: This study investigates the impact of the Doximity rankings on the rank list choices made by residency applicants in emergency medicine (EM). Methods: We sent an 11-item survey by email to all students who applied to EM residency programs at four different institutions representing diverse geographical regions. Students were asked questions about their perception of Doximity rankings and how it may have impacted their rank list decisions. Results: Response rate was 58% of 1,372 opened electronic surveys. This study found that a majority of medical students applying to residency in EM were aware of the Doximity rankings prior to submitting rank lists (67%). One-quarter of these applicants changed the number of programs and ranks of those programs when completing their rank list based on the Doximity rankings (26%). Though the absolute number of programs changed on the rank lists was small, the results demonstrate that the EM Doximity rankings impact applicant decision-making in ranking residency programs. Conclusion: While applicants do not find the Doximity rankings to be important compared to other factors in the application process, the Doximity rankings result in a small change in residency applicant ranking behavior. This unvalidated ranking, based principally on reputational data rather than objective outcome criteria, thus has the potential to be detrimental to students, programs, and the public. We feel it important for specialties to develop consensus around measurable training outcomes and provide freely accessible metrics for candidate education. [ABSTRACT FROM AUTHOR]

The zooplankton of the northern California Current are typically characterized by an abundance of lipid-rich copepods that support rapid growth and survival of ecologically, commercially, and recreationally valued fish, birds, and mammals. Disruption of this food chain and reduced ecosystem productivity are often associated with climatic variability such as El Niño events. We examined the variability in timing, magnitude, and duration of positive temperature anomalies and changes in copepod species composition in the northern California Current in relation to 10 tropical El Niño events. Measurable impacts on mesozooplankton of the northern California Current were observed during seven of 10 of these events. The occurrence of anomalously warm water and the response of the copepod community was rapid (lag of zero to 2 months) following the initiation of canonical Eastern Pacific (EP) events, but delayed (lag of 2-8 months) following 'Modoki' Central Pacific ( CP) events. The variable lags in the timing of a physical and biological response led to impacts in the northern California Current peaking in winter during EP events and in the spring during CP events. The magnitude and duration of the temperature and copepod anomalies were strongly and positively related to the magnitude and duration of El Niño events, but were also sensitive to the phase of the lower frequency Pacific Decadal Oscillation. When fisheries managers and biological oceanographers are faced with the prospect of a future El Niño event, prudent management and observation will require consideration of the background oceanographic conditions, the type of event, and both the magnitude and duration of the event when assessing the potential physical and biological impacts on the northern California Current. [ABSTRACT FROM AUTHOR]

Copyright of Canadian Journal of Fisheries & Aquatic Sciences is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Coastal ocean ecosystems have always served human populations--they provide food security, livelihoods, coastal protection, and defense. Ocean acidification is a global threat to these ecosystem services, particularly when other local and regional stressors combine with it to jeopardize coastal health. Monitoring efforts call for a coordinated global approach toward sustained, integrated coastal ocean health observing networks to address the region-specific mix of factors while also adhering to global ocean acidification observing network principles to facilitate comparison among regions for increased utility and understanding. Here, we generalize guidelines for scoping and designing regional coastal ocean acidification observing networks and provide examples of existing efforts. While challenging in the early stages of coordinating the design and prioritizing the implementation of these observing networks, it is essential to actively engage all of the relevant stakeholder groups from the outset, including private industries, public agencies, regulatory bodies, decision makers, and the general public. The long-term sustainability of these critical observing networks will rely on leveraging of resources and the strength of partnerships across the consortium of stakeholders and those implementing coastal ocean health observing networks. [ABSTRACT FROM AUTHOR]

Fisheries oceanography is the study of ecological relationships between fishes and the dynamics of their marine environments and aims to characterize the physical, chemical, and biological factors that affect the recruitment and abundance of harvested species. A recent push within the fisheries management community is toward ecosystem-based management. Here, we show how physical and biological oceanography data can be used to generate indicators of ocean conditions in an ecosystem context, and how these indicators relate to the recruitment of salmonids, sablefish, sardines, and rockfish in the California Current. [ABSTRACT FROM AUTHOR]

Few fisheries oceanography surveys in the United States have sampled hydrography and ichthyoplankton or juvenile fishes for 15 years or more. We describe six long time series surveys, including three from the California Current System, and one each from Alaska (Gulf of Alaska, Bering Sea, and the Arctic), the Northeast US Shelf, and the Gulf of Mexico. We examine the applications of long time series data as well as the output of published analyses, Web-based graphical summaries, and quality controlled data to the broader scientific community (including resource managers and stakeholders). Potential improvements to the surveys using new technologies are evaluated, and possible changes in survey design are discussed. We conclude with a summary of the benefits derived from these long time series fisheries oceanography surveys and make the case for their continuation. [ABSTRACT FROM AUTHOR]

Copyright of Canadian Journal of Fisheries & Aquatic Sciences is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Academic Emergency Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Filtration by adult Euphausia pacifica was measured before and during the upwelling season, using both “disappearance of chlorophyll” and “disappearance of cells” techniques. Results show that feeding rates and selectivity varied with food assemblages. Filtration rate (F) was best modeled by the Ivlev function: the average F on total Chl-a was 92 mL euphausiid−1 h−1, and 119 mL euphausiid−1 h−1 on microscopy cell counts. F averaged 36 for the <5 µm size fraction of Chl-a, 94 for the 5–20 µm fraction and 107 mL euphausiid−1 h−1 for the >20 µm fraction. The average F values were 155 and 163 mL euphausiid−1 h−1 for chain-diatoms and single diatoms, respectively, and115 and 137 mL euphausiid−1 h−1 for the <40 µm and >40 µm ciliates, respectively. Ingestion rates based on total Chl-a and size fractions, total cell counts and ciliates were significantly correlated using Hollings' models (P < 0.01). Maximum daily ration was 23% body C day−1 when a high food concentration (700 µC L−1) was available, but over the carbon range of 50–200 µg C L−1, daily ration averaged 4% body C day−1. Diatoms were consumed almost exclusively during blooms associated with summer upwelling events; larger types of ciliates and dinoflagellates were fed upon preferentially compared with their smaller counterparts. [ABSTRACT FROM PUBLISHER]

Research on regulatory mechanisms in biological populations often focuses on environmental covariates. An integrated approach that combines environmental indices with organismal-level information can provide additional insight on regulatory mechanisms. Survival of spring/summer Snake River Chinook salmon (Oncorhynchus tshawytscha) is consistently low whereas some adjacent populations with similar life histories experience greater survival. It is not known if populations with differential survival respond similarly during early marine residence, a critical period in the life history. Ocean collections, genetic stock identification, and otolith analyses were combined to evaluate the growth-mortality and match-mismatch hypotheses during early marine residence of spring/summer Snake River Chinook salmon. Interannual variation in juvenile attributes, including size at marine entry and marine growth rate, was compared with estimates of survival and physical and biological metrics. Multiple linear regression and multi-model inference were used to evaluate the relative importance of biological and physical metrics in explaining interannual variation in survival. There was relatively weak support for the match-mismatch hypothesis and stronger evidence for the growth-mortality hypothesis. Marine growth and size at capture were strongly, positively related to survival, a finding similar to spring Chinook salmon from the Mid-Upper Columbia River. In hindcast models, basin-scale indices (Pacific Decadal Oscillation (PDO) and the North Pacific Gyre Oscillation (NPGO)) and biological indices (juvenile salmon catch-per-unit-effort (CPUE) and a copepod community index (CCI)) accounted for substantial and similar portions of variation in survival for juvenile emigration years 1998–2008 (R2>0.70). However, in forecast models for emigration years 2009–2011, there was an increasing discrepancy between predictions based on the PDO (50–448% of observed value) compared with those based on the NPGO (68–212%) or biological indices (CPUE and CCI: 83–172%). Overall, the PDO index was remarkably informative in earlier years but other basin-scale and biological indices provided more accurate indications of survival in recent years. [ABSTRACT FROM AUTHOR]