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Background: Gastrointestinal (GI) malignancies are increasing with advancing age. Various addictions and poor dietary habits are among the major risk factors. Early detection is difficult until patient notices symptoms. Primary prevention by knowing various risk factors and early symptom awareness will help in early diagnosis and better treatment outcome.Objectives: This study is carried out to see various addiction patterns, dietary habits, associated medical problems, and socioeconomic status with various sites involved in GI malignancies, at a tertiary care teaching hospital of Western Maharashtra, India.Materials and Methods: Prospective questionnaire-based study was carried out for 11 months. A total of 100 diagnosed carcinoma cases of GI tract malignancy were taken for study.Results and Conclusions: Out of total 100 cases, 61 were male and 39 were female. The most common site involved was esophagus (41) followed by rectosigmoid, colon and cecum, stomach, and anal canal (29, 14, 13, and 3, respectively). There were 45% of cases above 60 years of age. The most common addiction was smokeless tobacco. Most of the patients belonged to lower and upper lower class (64%). Majority of cases (81%) were nonvegetarian, only 16% were pure vegetarian. Most of the cases (85%) were in advanced stage of disease (III and IV). Awareness program for harmful effects of various addictions and importance of high-fiber diet (vegetarian diet) will help in health promotion and prevention of various malignancies. Awareness about the early symptoms of GI malignancy will help in early detection of disease and better treatment outcome. [ABSTRACT FROM AUTHOR]

Brain metastases from cancer cervix are extremely rare. We report a patient with squamous cell carcinoma of the cervix in a rural setting in western Maharashtra who developed an isolated right parafalcine high frontal metastasis within 6 months of treatment of the primary disease. The presenting symptoms of the metastatic disease were headache, seizures and vomiting. The patient was successfully treated by surgical excision of the metastasis and adjuvant whole brain radiation therapy, and she was disease-free at the 9-month follow-up after treatment of the recurrence. [ABSTRACT FROM AUTHOR]

Pattern of palliative radiotherapy delivered using Telecobalt machine for different malignant sites. Dr. Shreya Dwivedi, Post Graduate Student, Under the guidance of Dr. Vandana Jain, M.D, Professor & HOD Dr.Chaitali Waghmare, M.D, Dr.Gopal Pemmaraju, Dr.Mayuresh Virkar Department of Radiotherapy & Oncology, Rural Medical College, Pravara Institute of Medical Sciences, Loni 413736, Dist. Ahmednagar (M.S.) E-mail : oncology@pmtpims. org Abstract: Background : Majority of the patients with advanced or metastatic cancer need palliative radiotherapy for palliation of their symptoms. The purpose of this study was to assess pattern of palliative radiotherapy (PRT) delivered using Telecobalt machine for different malignances. Material and method: This was a retrospective analytical study. The case records of all patients who received radiotherapy (RT) on Telecobalt machine from 1st July 2015 to 31st July 2016 were screened. Patients receiving PTV on Telecobalt were included in the study. All patient and treatment related details were filled in a preformed proforma. Data entry was done in X-cel. Result: The study cohort was comprised of 61 patients. The median age was 56.11 years and male to female ratio was 1:1.4. Most common primary malignancy treated with PRT was head and neck cancer (24.59%), followed by genitourinary and gynecological (21.31%) and breast (16.39%). Squamous cell carcinoma (39.34%) was most common histopathology type followed by adeocarcinoma (34.42%). The disease was non-metastatic in 36.06% (22) and metastatic in 63.93% (39) cases. Majority (86.36%) were multiple metastasis and only three (13.63%) were oligometastasis. Twenty eight patients received RT at primary and or local lymph node site while 33 patients received PRT at metastatic site. Head and neck cancer (12) was the most common primary site receiving local RT for palliation followed by oesophagus (05) and cervix (04). Among the metastatic site bone metastasis was most commonly treated (72.72%). All patients received RT on daily basis. Two patients (3.27%) were treated with single fraction RT while 59 (96.72%) patients received fractionated RT. Commonly used dose fractionation schedule was 20 Gy in five fractions over a week (57.37%). Conclusion: RT is an effective treatment modality for palliation of both the primary and metastatic lesion. Short fractionation schedule is proffered over long. [ABSTRACT FROM AUTHOR]

CASE REPORT SECOND NEW PRIMARY OESOPHAGEAL CARCINOMA INCIDENTALLY DIAGNOSED IN A KNOWN CASE OF CARCINOMA CERVIX Dr mayuresh virkar post graduate in department of radiation and oncology, pravara medical trust, loni UNDER GUIDECE OF Dr vandana jain (HOD), MD DR CHAITALI WAGHMARE(MD) Dr. GOPAL PEMMARAJU(MD PG STUDENT) DR SHREYA DWIVEDI (PG STUDENT) DR NAMRATA BHAGAT (PG STUDENT ) Abstract Carcinoma oesophagus in a known case of carcinoma cervix (treated) is extremely rare. We report a case of carcinoma oesophagus incidentally diagnosed on OGD scopy with history of accidental straw ingestion while drinking juice in a treated case of carcinoma cervix. The patient was successfully treated with radical radiation therapy considering as second new primary. Introduction Oesophageal carcinoma is the eight most common cancers and sixth cause of all cancer deaths worldwide.[2] Most of the cases is seen in males with ratio of 4:1 in relation to females[6] Highest incidence is seen in china, Russia, Caspian region of Iran[6]. Squamous cell carcinoma and adenocarcinoma comprise of 95% of all oesophageal cancer, of which 90 percent are squamous cell carcinoma.[1] Over last 20 years there has being increase in the incidence of adenocarcinoma at a rate of 5 % to 10% per year due to exposure to air pollutants. Associated risk factors with carcinoma oesophagus is tobacco, smoking,, alcohol which is associated 80% to90% cases of squamous cell carcinoma [4] Other associated risk factors are Barrett's oesophagus, cardiac achalasia, tylosis. CASE REPORT • A 71 year old lady who was a diagnosed case of carcinoma cervix III B treated in 1997 who was treated with radical chemoradiotherapy at our rural centre. She was on regular follow up for five years. On January 2017 she accidently ingested straw while drinking juice, for which DL scopy and removal of straw was done and DL scopy was done to see the extent of trauma caused by straw. But on DL scopy growth was seen present at 25 cm from incisors. Biopsy from the growth shows moderately differentiated squamous cell carcinoma. On February 2017, after the positive report, patient reported in the department for further management. • Patient was examined for her primary which was under control and all routine haematological and radiological investigations were done. Barium swallow (27/02/2017)- Narrowing of segment seen at thoracic level at T7-T8 VERTEBRA showing shouldering sign with proximal dilatation of oesophagus with mucosal irregularity s/o neoplastic lesion. CT Thorax - neoplastic mass lesion extending from T6 vertebra to GE junction with mediastinal lymphadenopathy • After clinical and radiological work up patient was treated by radiotherapy by 3DCRT to the total dose of 60GY in 30# with concurrent weekly chemotherapy (cisplatin 30 mg/m2). Patient tolerated treatment well. After completion of treatment in April 2017, patient is on follow up CONCLUSION • It has been observed at our rural centre that cancer disease remain unreported in most of the cases as most of them are asymptomatic, neglected and lack of awareness. This case is unique as this patient already had cancer of cervix for which she had taken treatment at our centre in 1997, now she being incidentally diagnosed with second new primary with carcinoma oesophagus and treated well. [ABSTRACT FROM AUTHOR]