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1. Successful therapeutic use of rituximab in refractory membranous glomerulonephritis.

Author

Cobo, M., Hernández, D., Rodriguez, C., and Pérez-Tamajón, L.

Subjects
NEPHROTIC syndrome, GLOMERULONEPHRITIS, ACE inhibitors, ANGIOTENSIN-receptor blockers, SERUM albumin, PROTEINURIA
Abstract

We present the case of a 57-year-old man with nephrotic syndrome secondary to idiopathic membranous glomerulonephritis unsuccessfully treated with angiotensin-converting enzyme inhibitor (ACEI), angiotensin II receptor antagonist (ARA), prednisone and chlorambucil. After treatment with rituximab, we observed a progressive decrease of proteinuria and normalization of serum albumin. 18 months after treatment, he remained in remission. No adverse reactions to rituximabwere noted throughout follow-up. [ABSTRACT FROM AUTHOR]

Published
2006
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