1. Two cases of transplant-acquired food allergy who developed resensitization after a negative oral food challenge.
- Author
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Nakaoka, Akiko, Nomura, Takayasu, Ozeki, Kazuyoshi, Suzuki, Tomotaka, Kusumoto, Shigeru, Iida, Shinsuke, and Saitoh, Shinji
- Subjects
FOOD allergy ,CORD blood transplantation ,MILK allergy ,PEANUT allergy ,HEMATOPOIETIC stem cells ,LIVER transplantation ,TRANSPLANTATION of organs, tissues, etc. - Abstract
Background: Cases of food allergy after hematopoietic stem cell and solid organ transplantation in previously nonallergic transplant recipients were reported as transplant-acquired food allergy (TAFA), but information about its long-term outcome is still limited. A phenomenon where patients reacquire food allergy by resuming daily consumption after a negative oral food challenge has not yet been reported. Case presentation: We report two cases of TAFA after liver transplantation and cord blood transplantation. In each case, the threshold of daily consumption to cause allergic symptoms decreased when a negative oral food challenge was obtained. Conclusions: Our cases show an importance of gastrointestinal tract as a route of food sensitization because thresholds that caused allergic reactions decreased during their resuming process. We need to be careful with possible resensitization once a negative substantial dose was confirmed. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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