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Aims While elevated levels of anxiety are associated with worse prognosis of cardiovascular disease (CVD), this association may vary between different aspects of anxiety. The aim of this study was to analyse self-reported behavioural, physiological, affective, and cognitive aspects of anxiety and their relation to the risk of recurrent CV events. Methods and results This prospective cohort study utilized data from the U-CARE Heart trial. Participants (N = 935, post myocardial infarction) answered the Hospital Anxiety and Depression Scale (HADS: Anxiety subscale) and the Cardiac Anxiety Questionnaire (CAQ: Fear, Avoidance & Attention subscales). HADS Anxiety reflected physiological aspects, CAQ Fear reflected cognitive and affective aspects, CAQ Avoidance reflected behavioural aspects, and CAQ Attention reflected cognitive aspects of anxiety. Cox regression was used to estimate the risk between anxiety and recurrent major adverse cardiac event (MACE). During the follow-up period (mean 2.9 years), 124 individuals (13%) experienced a specified MACE endpoint. HADS Anxiety and CAQ Total were both associated with increased risk of MACE [hazard ratio (HR) = 1.52, 95% confidence interval (CI): 1.15–2.02 and HR = 1.30, 95% CI: 1.04–1.64, respectively]. Among the CAQ subscales, there was support for an association between Avoidance and risk of MACE (HR = 1.37, 95% CI 1.15–1.64), but not for Attention and Fear. Conclusion The results support that anxiety is associated with an increased risk of recurrent MACE in post-myocardial infarction patients. The association between anxiety and risk was strong for the aspects of anxiety relating to behaviour and physiology, while the support for an association with cognitive and affective aspects was lacking. [ABSTRACT FROM AUTHOR]

Introduction: Poor mental health in young people has become a growing problem globally over the past decades. However, young people have also been shown to underutilize available healthcare resources. The World Health Organisation (WHO) has formulated guidelines for youth-friendly health services (YFHSs) to increase youth participation in healthcare. Still, little is known about how young people using these services perceive mental health, indicating a knowledge gap concerning the subjective evaluation of their mental health. Aim: To investigate how young people visiting youth health clinics (YHC) perceive the concept of mental health and factors they view as central to maintaining mental health. Methods: In total 21 interviews were carried out, 16 in 2018, and 5 in 2023 to assure no changes in findings after the COVID-19 pandemic. Subjects were recruited during visits to youth health clinics (YHCs) in mid-Sweden and were aged 15–23 years. Recruitment strived to achieve heterogeneity in the sample concerning gender, sexual orientation, gender identity and age. Interviews were transcribed and analysed using qualitative content analysis. Findings: Findings of the analysis revealed two themes, "Mental health is helped and hindered by the surroundings" and "Mental health is difficult to understand and difficult to achieve". The participants described their health as highly dependent on their social surroundings, and that these are important to maintaining health but may also affect health negatively. They described mixed experiences of the health care services and mentioned prerequisites for seeking care for mental health problems such as accessibility and respect for their integrity, including the right to turn down offered treatment. The informants also viewed mental health as an ongoing undertaking that one must work for, and that it is sometimes difficult to know what constitutes mental health. They also expressed a need from healthcare services to enquire about their health, and to show an active interest in how they are doing. Conclusions: Findings underline the need of young people's individual needs to be met in the healthcare system and their vulnerability to their social surroundings. Health status assessments in young people should consider social and individual factors to fully capture mental health. [ABSTRACT FROM AUTHOR]

The value problem for knowledge is the problem of explaining why knowledge is more valuable than mere true belief. The problem arises for reliabilism in particular, i.e., the externalist view that knowledge amounts to reliably acquired true belief. Goldman and Olsson argue that knowledge, in this sense, is more valuable than mere true belief due to the higher likelihood of future true beliefs (produced by the same reliable process) in the case of knowledge. They maintain that their solution works given four empirical assumptions, which they claim hold "normally." However, they do not show that their assumptions are externalistically acceptable; nor do they provide detailed evidence for their normality claim. We address these remaining gaps in Goldman and Olsson's solution in a constructive spirit. In particular, we suggest an externalist interpretation of the assumptions such that they essentially spell out what it means for a broad range of organisms capable of belief-like representations to be epistemically adapted to their environment. Our investigation also sheds light on the circumstances in which the assumptions fail to hold and knowledge therefore fails to have extra value in Goldman and Olsson's sense. The upshot is a deeper understanding of their solution as a contribution to naturalized epistemology and a strengthened case for its empirical validity. [ABSTRACT FROM AUTHOR]

Objective: This study sought to investigate interactive participation and content of a moderated discussion forum within a web‐based psychoeducational intervention aimed at alleviating sexual dysfunction and fertility distress in young adults diagnosed with cancer. Methods: The study is part of the Fex‐Can Young Adult randomized controlled trial (RCT), in which young adults with self‐reported sexual dysfunction or fertility distress were invited to participate. This study focuses on RCT participants that were randomized into the intervention condition. Sociodemographics and clinical characteristics of intervention participants and level of activity in the intervention were analyzed with descriptive statistics and compared between subgroups ("high" and "low" activity participants). Inductive qualitative thematic analysis was used to analyze the posts in the discussion forum. Results: Of 135 intervention participants, 24% met the criteria for high activity participation. There were no statistically significant differences found in terms of clinical and sociodemographic characteristics between high and low activity participants. Ninety‐one participants (67%) accessed the discussion forum, and 19 (14%) posted at least once. Posters shared intimate details of their experiences of sexuality and fertility following cancer. The thematic analysis of posts resulted in four themes: fertility fears, perceptions of the changed body, missing out on life, and importance of support and information. Conclusions: While a smaller proportion of participants posted in the discussion forum, a majority spent time reading posts (lurkers). Participants posting in the forum shared experiences of intimate relationships, body image, parenthood concerns, and support needs. The discussion forum was used by a majority of intervention participants, and provided appreciated support for those who posted in the forum. We therefore recommend similar interventions to include this opportunity for interaction and communication. [ABSTRACT FROM AUTHOR]

Background: - An estimated 240,000 newborns die worldwide within 28 days of birth every year due to congenital birth defect. Exposure to poor indoor environment contributes to poor health outcomes. In this research, we aim to evaluate the association between the usage of different type household cooking fuel and congenital birth defects in Nepal, as well as investigate whether air ventilation usage had a modifying effect on the possible association. Methods: - This is a secondary analysis of multi-centric prospective cohort study evaluating Quality Improvement Project in 12 public referral hospitals of Nepal from 2017 to 2018. The study sample was 66,713 women with a newborn, whose information was available in hospital records and exit interviews. The association between cooking fuel type usage and congenital birth defects was investigated with adjusted multivariable logistic regression. To investigate the air ventilation usage, a stratified multivariable logistic regression analysis was performed. Results: -In the study population (N = 66,713), 60.0% used polluting fuels for cooking and 89.6% did not have proper air ventilation. The prevalence rate of congenital birth defect was higher among the families who used polluting fuels for cooking than those who used cleaner fuels (5.5/1000 vs. 3.5/1000, p < 0.001). Families using polluting fuels had higher odds (aOR 1.49; 95% CI; 1.16, 1.91) of having a child with a congenital birth defect compared to mothers using cleaner fuels adjusted with all available co-variates. Families not using ventilation while cooking had even higher but statistically insignificant odds of having a child with congenital birth defects (aOR 1.34; 95% CI; 0.86, 2.07) adjusted with all other variates. Conclusion: - The usage of polluted fuels for cooking has an increased odds of congenital birth defects with no significant association with ventilation. This study adds to the increasing knowledge on the adverse effect of polluting fuels for cooking and the need for action to reduce this exposure. [ABSTRACT FROM AUTHOR]

Decolonisation aims at exposing the ills of colonialism in an attempt to undo their long-standing effects. Important criticism of curriculum decolonisation has focused on potential conflicts with academic freedom. However, this criticism has to some extent suffered from a perceived lack of agreement on the concept and status of academic freedom itself. The present study views decolonisation in South Africa from the perspective of the international standard afforded by the UNESCO recommendation concerning the status of higher-education teaching personnel (1997). It is argued that, whereas some conceptions of decolonisation are intrinsically in conflict with the recommendation, compliance depends in other cases on implementational details. Moreover, regarding several conceptions, furthering decolonisation and implementing the UNESCO recommendation go hand in hand. In a case study, the Nelson Mandela University Transformation Plan 2018–2020 is critically examined. Finally, it is suggested that there may be considerable benefits associated with using the UNESCO recommendation as a guide in and throughout curriculum transformation. [ABSTRACT FROM AUTHOR]

Interlayers in asphalt pavements are potential structural damage initiators. In order to better understand the quantitative role of interlayer parameters, such as surface roughness, binder type, binder content and loading type on interlayer shear strength, this paper focuses on the effects of particle interlock and contact conditions on interlayer strength through experimental and numerical modelling. Experimentally, interlayer shear box strength tests on a model material consisting of stiff binder blended with steel balls are performed with and without normal force confinement. A Discrete Element method model of the test is developed using measurements of the model material for calibrating the contact law and for validating the model. It is shown that this model captures adequately the measured force-displacement response of the specimens. It is thus a feasible starting point for numerically and experimentally studying the role of binder and tack coat regarding interlayer shear strength of real asphalt layers. [ABSTRACT FROM AUTHOR]

Aims: Most cases of acute myocardial infarction (MI) in Sweden are treated with long-term β-blocker therapy as secondary prevention. Case studies and patient reports have indicated negative effects of β-blockers including symptoms of depression, fatigue, sexual dysfunction, and general low mood, all related to reduced quality of life (QoL). To date, no recent large-scale, randomized trial has explored the effects of β-blockers on these factors. Methods and results: The ongoing Randomized Evaluation of Decreased Usage of beta-bloCkErs after myocardial infarction (REDUCE): quality of life (RQoL) study is a multicentre, prospective, randomized pre-specified substudy aiming to evaluate the effects of β-blockers on self-reported measures of QoL. Following randomized allocation to long-term β-blocker or no β-blocker treatment, patients complete a total of six baseline measures pertaining to QoL, sexual functioning, and perceived side effects. Data collection is optionally carried out online through a unique and secure portal and repeated again at two follow-up time points. Recruitment began in July 2018. Data from the first 100 patients showed that at the first follow-up, 93% had completed the questionnaires, which decreased to 81% at the second follow-up. The method of digital data collection was utilized by over half of the patients recruited so far. Conclusion: Data from the first 100 patients indicate success in terms of study design and recruitment. The RQoL substudy investigates the effects of β-blockers on self-reported measures of QoL in MI patients and will potentially contribute to the limited knowledge of QoL-related side effects reported in conjunction with β-blocker use. Clinical trial registration: Eudra CT number, 2017-002336-17; Clinical trial.gov identifier, NCT03278509 Graphical abstract [ABSTRACT FROM AUTHOR]

Protected area (PA) sustainability is challenged worldwide by legal downgrading, downsizing, and degazettement (PADDD). National and local case studies of ecologically destructive PADDD events provide useful insights that may help respond to or prevent future events. Using information from legal documents and expert input, we identified 37 PADDD events that affected two adjacent PAs in northeastern Cambodia differently despite similar economic, environmental, and social conditions. Important differences in local context led to the eventual degazettement (100% loss) of one PA and downsizing (10.49% loss) of the other, the rest of which remains protected. This case study confirms the contribution of secure Indigenous land tenure to durable conservation governance and demonstrates the importance of investing in site‐level capacity to ensure that social and ecological conditions are monitored and proposed PADDD events can be successfully challenged. [ABSTRACT FROM AUTHOR]

Background: The purpose of this study was to investigate whether treatment of a depressive episode with intermittent theta burst stimulation (iTBS) over the dorsomedial prefrontal cortex (DMPFC) had any effects on heart rate variability (HRV). We also investigated if changes in HRV covaried with symptom change after iTBS and if HRV could predict symptom change. Methods: We included 49 patients with a current depressive episode. All were randomized to receive a double-blind treatment course with active or sham iTBS over the DMPFC. HRV data were obtained from 1 h of night data before and after the iTBS. The standard deviation of the RR interval (SDNN) was chosen as primary outcome measure. Depressive, negative, and anxiety symptoms as well as self-rated health were assessed by clinicians or by self-report. Results: The groupxtime linear mixed model revealed no effect of iTBS on SDNN (estimate = -1.8, 95% confidence interval [CI]: -19.9 to 16.2). There were neither correlations between HRV and depressive, negative, or anxiety symptom change after iTBS nor with self-assessed health. No predictive value of HRV was found. Conclusions: Treatment for depression with dorsomedial iTBS had neither negative nor positive effects on the cardiac autonomic nervous system. [ABSTRACT FROM AUTHOR]

Myocardial infarction (MI) is one of the leading causes of mortality and disability worldwide. Emotional distress, such as anxiety and depression, are common among MI patients. The aim of this study was to investigate emotional reactions following MI and to explore how MI patients self-manage their emotional distress using the perspective of an explanatory behavioural model of depression and anxiety. Written testimonies from 92 MI patients starting an internet-based cognitive behavioural therapy (iCBT) were analysed using qualitative content analysis with a mixed deductive and inductive approach. Six themes were identified. The first three highlight the emotional reactions post-MI: Hypoarousal reactions and low mood; Hyperarousal reactions; and A changed sense of self and outlook on life. The following three themes describe strategies for managing emotional distress: Avoidance of potentially rewarding situations; Avoidance of heart relevant stimuli triggering anxiety; and Engaging in potentially positive activities and acceptance. The MI experience may trigger emotional reactions, with a particular emphasis on heart-focused anxiety, depression and a shift in the perception of one's identity. Patients tend to manage emotional distress through social withdrawal and experiential avoidance which likely maintains the distress. Applying a behavioural model to the management of emotional distress following MI is suited. [ABSTRACT FROM AUTHOR]

Background: CVD-patients with higher levels of cardiac anxiety suffer psychologically, as well as being at increased risk for cardiac morbidity and mortality. Therefore it is important to be able to assess CA in a clinical setting. It is currently measured with the Cardiac Anxiety Questionnaire, which has conflicting findings regarding its factor structure, and it has not been validated in a Swedish population. This study aimed to examine the factor structure of CAQ and its psychometric properties in a Swedish CVD-population. Methods: Nine hundred thirty patients post-MI were recruited at different Swedish hospitals and completed the CAQ, along with several other questionnaires. Exploratory factor analysis and confirmatory factor analysis were conducted to explore factor structure and to inspect various factor solutions from previous research. Standard psychometric tests were performed for the CAQ to test its validity and reliability. Results: The exploratory analysis found a model with the factors Fear/Worry, Avoidance and Attention. The confirmatory factor analysis indicated that a 3-factor solution best fitted the data, but with certain items removed. Additionally, psychometric properties turned out acceptable in a Swedish post-MI population. Conclusions: We conclude that the original 3-factor structure of the CAQ is valid, but that the questionnaire could be revised in regard to some items. A shorter 10-items version could also be considered. We also confirm that the CAQ is a valid instrument to measure CA in a Swedish MI-population. Trial registration: The study was registered on ClinicalTrials.gov on 05/01/2012 (NCT01504191). [ABSTRACT FROM AUTHOR]

Summary: Acute lymphoblastic leukaemia (ALL) has a high survival rate, but treatment is lengthy with risk of severe side‐effects, which may also impact parents' health‐related quality of life (HRQOL). We present data on 526 parents of 310 children treated for ALL according to the NOPHO ALL2008‐protocol, in Sweden, Finland and Denmark. Parents were asked to complete the 36‐Item Short Form Survey (SF‐36) at least 6 months after end of treatment and data were compared with Norwegian reference data. Parental background factors were collected via a study‐specific questionnaire. Participating parents scored significantly lower than the reference population on both physical and mental summary indexes, but only surpassed a minimal clinically important difference for the mental summary index (Mental Component Summary [MCS]). Mothers scored lower than fathers in the MCS and stopped working and took care of the affected child more often than the fathers. Higher mental HRQOL was associated with male gender and living in Finland or Denmark (compared to Sweden). Correlations within spouses in physical and mental scores were weak to moderate. In conclusion, ALL negatively affects parental HRQOL, especially the mental domains, even after treatment. Findings suggest that mothers are more affected than fathers and may require extra support. [ABSTRACT FROM AUTHOR]

Background: In the aftermath of a myocardial infarction with non-obstructive coronary arteries (MINOCA) or Takotsubo syndrome (TS), patients commonly express high levels of stress and anxiety. Current treatment alternatives rarely address these issues.Methods: The study is a randomised controlled trial, where 90 patients with a discharge diagnosis of MINOCA or TS who also report symptoms of stress or anxiety will be randomised 2-6 weeks after their cardiac event. The treatment consists of 10 weeks of Internet-based cognitive behaviour therapy (CBT) and starts immediately after randomisation for the treatment group. The control group receives usual care. Main outcomes are symptoms of anxiety measured with the Hospital Anxiety and Depression scale, anxiety subscale, and perceived stress measured with the Perceived Stress Scale, 14-item version, 10 weeks after randomisation. Secondary measures include cardiac specific anxiety, symptoms of post-traumatic stress, quality of life, cortisol measured in hair and physiological stress responses (heart rate variability, blood pressure and saliva cortisol) during a stress procedure. Ten weeks after randomisation, the control group will also receive treatment. Long-term follow-up in the self-report measures mentioned above will be conducted 20 and 50 weeks after randomisation where the total group's development over time is followed, and the groups receiving intervention early versus late compared.Discussion: At present, there are no randomised studies evaluating psychological treatment for patients with MINOCA or TS. There is an urgent need for treatment alternatives aiming at relieving stress and anxiety considering the high mental stress and anxiety levels observed in MINOCA and TS, leading to decreased quality of life. CBT aiming at reducing mental stress has been shown to be effective regarding prognosis in patients with coronary artery disease. The current protocol describes a randomised open-label controlled trial evaluating an Internet-based CBT program for reduction of stress and anxiety in patients with increased mental stress and/or anxiety with a discharge diagnosis of either MINOCA or TS.Trial Registration: ClinicalTrials.gov NCT04178434 . Registered on 26 November 2019. [ABSTRACT FROM AUTHOR]

The study aimed to explore the self-perceived cognitive status and cognitive challenges associated with lifestyle changes in cardiac rehabilitation among elderly myocardial infarction (MI) patients (≥65 years). Further, the study explored coping strategies developed to manage these challenges in the everyday life. Nine patients were included in the study. Data were collected by telephone or in person, between 6 and 12 weeks post MI, using semi-structured interviews. Data were analysed inductively, using thematic analysis. Four major themes were identified, highlighting elderly MI patients' experiences of their cognitive status and cardiac rehabilitation management: (1) A change in cognition over time, (2) Situating the MI within a challenging and changing life context, (3) Navigating the hurdles of cardiac rehabilitation, and (4) Being seen within the healthcare system. Elderly MI patients are situated in a complex life context, dealing with a transition to retirement, multiple health issues and age-related cognitive decline. In this context, the MI experience is marginalised, and cognitive decline normalized. By adopting individually tailored interventions and improving healthcare provider continuity and accessibility, cognitive challenges associated with cardiac rehabilitation could be easier to overcome. Self-perceived cognitive impairment, in particular regarding memory, seems fairly common among elderly MI patients and should likely be identified prior to hospital discharge in order to optimize the prospects of self-care. There seems to exist an unmet need to implement the practice of individually adapted education and information further, in accordance with current recommendations for elderly cardiac patients. The overall health and cognitive status, social network and the objective living conditions (e.g., distance from service and housing) should be taken into account when planning the patient's cardiac rehabilitation management. Healthcare providers likely need to strengthen the continuity of care and increase its accessibility for elderly MI patients, in particular following the transfer from hospital care to local health centres. [ABSTRACT FROM AUTHOR]

Simple Summary: Gene expression signatures can provide important information on the risk of recurrence in patients with hormone receptor positive early breast cancer, and they can guide postoperative treatment. We have investigated how the implementation of gene-expression-based risk signatures with the Prosigna® test impacted patient management in Sweden. The two major conclusions of this study are that prognostic factors derived from routine pathology were poor predictors of the intrinsic subtype and the risk of recurrence score, and that gene-expression-based risk combined with clinicopathological biomarkers (tumor size, Ki67, tumor grade) spared patients from adjuvant chemotherapy, but also identified patients who would potentially benefit from this treatment. Molecular signatures to guide decisions for adjuvant chemotherapy are recommended in early ER-positive, HER2-negative breast cancer. The objective of this study was to assess what impact gene-expression-based risk testing has had following its recommendation by Swedish national guidelines. Postmenopausal women with ER-positive, HER2-negative and node negative breast cancer at intermediate clinical risk and eligible for chemotherapy were identified retrospectively from five Swedish hospitals. Tumor characteristics, results from Prosigna® test and final treatment decision were available for all patients. Treatment recommendations were compared with the last version of regional guidelines before the introduction of routine risk signature testing. Among the 360 included patients, 41% (n = 148) had a change in decision for adjuvant treatment based on Prosigna® test result. Out of the patients with clinical indication for adjuvant chemotherapy, 52% (n = 118) could avoid treatment based on results from Prosigna® test. On the contrary, 23% (n = 30) of the patients with no indication were escalated to receive adjuvant chemotherapy after testing. Ki67 could not distinguish between the Prosigna® risk groups or intrinsic subtypes and did not significantly differ between patients in which decision for adjuvant therapy was changed based on the test results. In conclusion, we report the first real-world data from implementation of gene-expression-based risk assessment in a Swedish context, which may facilitate the optimization of future versions of the national guidelines. [ABSTRACT FROM AUTHOR]

Context: Neuropsychiatric symptoms are common features of Graves disease (GD) in hyperthyroidism and after treatment. The mechanism behind these symptoms is unknown, but reduced hippocampal volumes have been observed in association with increased thyroid hormone levels. Objective: This work aimed at investigating GD influence on regional medial temporal lobe (MTL) volumes. Methods: Sixty-two women with newly diagnosed GD underwent assessment including magnetic resonance (MR) imaging in hyperthyroidism and 48 of them were followed up after a mean of 16.4 ± 4.2 SD months of treatment. Matched thyroid-healthy controls were also assessed twice at a 15-month interval. MR images were automatically segmented using multiatlas propagation with enhanced registration. Regional medial temporal lobe (MTL) volumes for amygdalae and hippocampi were compared with clinical data and data from symptom questionnaires and neuropsychological tests. Results: Patients had smaller MTL regions than controls at inclusion. At follow-up, all 4 MTL regions had increased volumes and only the volume of the left amygdala remained reduced compared to controls. There were significant correlations between the level of thyrotropin receptor antibodies (TRAb) and MTL volumes at inclusion and also between the longitudinal difference in the levels of free 3,5,3′-triiodothyronine and TRAb and the difference in MTL volumes. There were no significant correlations between symptoms or test scores and any of the 4 MTL volumes. Conclusion: Dynamic alterations in the amygdalae and hippocampi in GD reflect a previously unknown level of brain involvement both in the hyperthyroid state of the condition and after treatment. The clinical significance, as well as the mechanisms behind these novel findings, warrant further study of the neurological consequences of GD. [ABSTRACT FROM AUTHOR]

It has been argued that much of contemporary epistemology can be unified under Carnap's methodology of explication, which originated in the neighboring field of philosophy of science. However, it is unclear to what extent epistemological theories that emphasize the explanatory role of knowledge fit into this picture, Kornblith's natural kind epistemology and Williamson's knowledge first approach being cases in point. In this connection, I raise three questions. Can we harvest the insights of these approaches without loss in the more standard and less idiosyncratic explicationist framework? Can we do so without falling prey to prominent criticism raised against those approaches? Finally, do the approaches come out as coherent under an explicationist rendering? I argue that in Kornblith's case the answer to all three questions is essentially in the affirmative. Much of the knowledge first approach is also translatable into explicationism. However, from that perspective, Williamson's central argument for treating knowledge as undefinable, referring to persistent yet unsuccessful attempts to solve the Gettier problem, amounts to an overreaction to that problem. Leaving explicationism aside, I ask, in the penultimate section, what Williamson's own philosophical method really amounts to. [ABSTRACT FROM AUTHOR]

Denmark, Sweden and the Netherlands have different historical patterns of industrialization, but developed similar patterns of industrial coordination and cooperation. Theories accounting for industrial relations systems (economic structure, power resources, and party/electoral systems) have difficulty accounting for the similarities among these cases. Therefore, we explore the historical depictions of labor appearing in literature to evaluate whether cross-national distinctions in cultural conceptions of labor have some correspondence to distinctions between coordinated and liberal industrial relations systems. We hypothesize that historical literary depictions of labor are associated with the evolution of industrial systems, and apply computational text analyses to large corpora of literary texts. We find that countries (Denmark, Sweden and the Netherlands) with coordinated, corporatist industrial relations in the 20th century share similar cultural constructions about labor relations dating back to at least 1770. Literary depictions found in modern coordinated/corporatist countries are significantly different from those found in Britain, a country with liberal/pluralist industrial relations systems. The research has significance for our understanding of the role of culture in the evolution of modern political economies. [ABSTRACT FROM AUTHOR]

The generality problem is commonly considered to be a critical difficulty for reliabilism. In this paper, we present a dynamical perspective on the problem in the spirit of naturalized epistemology. According to this outlook, it is worth investigating how token belief-forming processes instantiate specific types in the biological agent's cognitive architecture (including other relevant embodied features) and background experience, consisting in the process of attractor-guided neural activation. While our discussion of the generality problem assigns "scientific types" to token processes, it represents a unified account in the sense that it incorporates contextual and common sense features emphasized by other authors. [ABSTRACT FROM AUTHOR]

Air pistol shooting is a complex sport discipline with high demands on fine motor control and postural stability. Earlier studies have reported questionable results regarding the most important technical components for air pistol shooting. Therefore, the aims of the present study were to investigate the key technical components for air pistol shooting and also to investigate how well the key technical components explain the performance in air pistol shooting. Eighteen national-level air pistol shooters completed a simulated qualifying round consisting of 60 shots. During each shot, shooting score and 17 aiming point trajectory variables were measured with an optoelectronic training device. Principal component analysis revealed five key technical components: aiming time, stability of hold, aiming accuracy, cleanness of triggering and timing of triggering. Four of the five components (not aiming time) correlated significantly (r =.48 –.74; p < 0.05) with shooting score. Two stepwise multiple regression analyses identified aiming accuracy followed by timing of triggering and stability of hold as the most important components, accounting for 75–78% of the variance in shooting score. Accordingly, these components should be in focus by coaches and athletes when conducting tests and training. [ABSTRACT FROM AUTHOR]

Background: The resurgence of measles globally and the increasing number of unvaccinated clusters call for studies exploring factors that influence measles vaccination uptake. Armenia is a middle-income post-Soviet country with an officially high vaccination coverage. However, concerns about vaccine safety are common. The purpose of this study was to measure the prevalence of measles vaccination coverage in children under three years of age and to identify factors that are associated with measles vaccination in Armenia by using nationally representative data.Methods: Cross-sectional analysis using self-report data from the most recent Armenian Demographic Health Survey (ADHS VII 2015/16) was conducted. Among 588 eligible women with a last-born child aged 12-35 months, 63 women were excluded due to unknown status of measles vaccination, resulting in 525 women included in the final analyses. We used logistic regression models in order to identify factors associated with vaccination status in the final sample. Complex sample analyses were used to account for the study design.Results: In the studied population 79.6% of the children were vaccinated against measles. After adjusting for potential confounders, regression models showed that the increasing age of the child (AOR 1.07, 95% CI: 1.03-1.12), secondary education of the mothers (AOR 3.38, 95% CI: 1.17-9.76) and attendance at postnatal check-up within two months after birth (AOR 2.71, 95% CI: 1.17-6.30) were significantly associated with the vaccination status of the child.Conclusions: The measles vaccination coverage among the children was lower than the recommended percentage. The study confirmed the importance of maternal education and attending postnatal care visits. However, the study also showed that there might be potential risks for future measles outbreaks because of delayed vaccinations and a large group of children with an unknown vaccination status. [ABSTRACT FROM AUTHOR]

The article demonstrates how large social associations are operating at the locus of a community-making related to the networks of Swedish migrants in Southern Spain. The associations are selectively targeting relatively wealthy older (ethnic) Swedish individuals, offering them a home-like social arena with access to a club equipped with well-known facilities and activities from the Swedish tradition. In addition, these associations offers valuable information and services that ensure their members a comfortable lifestyle in Spain but also facilitates a life with close connection to the Swedish society. In this social space, the Swedish migrants meet, socialise and to some extent, consume, rather than making efforts to participate and becoming integrated in Spanish society. It is also obvious how this environment becomes a hub for maintaining links and societal life with the Swedish society. The article argues that the practices used by the social associations in their mobilisation, are becoming part of a 'diasporisation' of Swedes in Southern Spain. It is also argued that these practices are both reflecting assumed needs and requests from the individuals in the migrant networks as well as orientating them into a lifestyle that promotes comfort and transnational links with their country of origin. [ABSTRACT FROM AUTHOR]

This article discusses how migrants from the Middle East are accounting for their successful career pathways as businessperson and academics in the Swedish society. It demonstrates how the stories of these individuals reveal strategies for mobilising the forms of capital that assumes to promote career advancement. It argues that the migrants accentuate a ‘middle-class standpoint’ with a priority on education; the capital mobilised in their country of origin is ‘reinvested’ in studies and the making of new contacts in the Swedish society. The article concludes that these stories are significantly shaped by the individuals’ professional position and class background but indirectly also by their foreign background. The article also reveals that the conditions set for successful career achievement require individual strategies that pragmatically downplay differences in societies as well as ethnicity and disregard the influence of discrimination. [ABSTRACT FROM AUTHOR]

The main issue in the epistemology of peer disagreement is whether known disagreement among those who are in symmetrical epistemic positions undermines the rationality of their maintaining their respective views. Douven and Kelp have argued convincingly that this problem is best understood as being about how to respond to peer disagreement repeatedly over time, and that this diachronic issue can be best approached through computer simulation. However, Douven and Kelp's favored simulation framework cannot naturally handle Christensen's famous Mental Math example. As a remedy, I introduce an alternative (Bayesian) simulation framework, Laputa, inspired by Alvin Goldman's seminal work on veritistic social epistemology. I show that Christensen's conciliatory response, reasonably reconstructed and supplemented, gives rise to an increase in epistemic (veritistic) value only if the peers continue to recheck their mental math; else the peers might as well be steadfast. On a meta-level, the study illustrates the power of Goldman's approach when combined with simulation techniques for handling the computational issues involved. [ABSTRACT FROM AUTHOR]

Competition, free movement and procurement are interrelated concepts that have long influenced the discretionary power of public authorities in the European Union to provide services through cooperation with other authorities. This contribution delves into this important issue, which should regain new attention because of the Irgita case before the CJEU. This case has seemingly created a legal conundrum for public cooperation and framework agreements. The discussion in this contribution brings to light the broad implications of this judgement for these two types of cooperation, and poses the question if the influence of EU public procurement law has made it (nearly) impossible to cooperate accordingly in the future. [ABSTRACT FROM AUTHOR]

Our beliefs and opinions are shaped by others, making our social networks crucial in determining what we believe to be true. Sometimes this is for the good because our peers help us form a more accurate opinion. Sometimes it is for the worse because we are led astray. In this context, we address via agent-based computer simulations the extent to which patterns of connectivity within our social networks affect the likelihood that initially undecided agents in a network converge on a true opinion following group deliberation. The model incorporates a fine-grained and realistic representation of belief (opinion) and trust, and it allows agents to consult outside information sources. We study a wide range of network structures and provide a detailed statistical analysis concerning the exact contribution of various network metrics to collective competence. Our results highlight and explain the collective risks involved in an overly networked or partitioned society. Specifically, we find that 96% of the variation in collective competence across networks can be attributed to differences in amount of connectivity (average degree) and clustering, which are negatively correlated with collective competence. A study of bandwagon or "group think" effects indicates that both connectivity and clustering increase the probability that the network, wholly or partly, locks into a false opinion. Our work is interestingly related to Gerhard Schurz's work on meta-induction and can be seen as broadly addressing a practical limitation of his approach. [ABSTRACT FROM AUTHOR]

This article examines the career narratives of entrepreneurs with migrant background in the Swedish business sector. Statistics show that the proportion of individuals with a migrant background who reach so-called top-positions in Swedish society is in general low. Migrants with Iranian background is an exception as many of them have reached high positions as professionals in business corporations and themselves established high-profile businesses in Sweden. Based on in-depth interviews with entrepreneurs and managers with Iranian origin, we will in this article look at how their background is made relevant when reflecting upon professional success and failure. The article is concerned with their exceptional professional achievements and, in particular, the individuals' positioning in relation to their 'society of migration', their society of origin, and the social networks are embedded in as migrants with an Iranian origin. The article shows how narratives of success tend to emphasize the struggles of a 'lonely fighter' while at the same time dismiss discrimination as an explanatory factor. The entrepreneurs' success stories nevertheless focus on how one's career path as innovators and 'agents of social change' is intimately linked with a migrant past and experience. [ABSTRACT FROM AUTHOR]

In a legendary technical report, the Google founders sketched a wisdom-of-crowds justification for PageRank arguing that the algorithm, by aggregating incoming links to webpages in a sophisticated way, tracks importance (quality, relevance, etc.) on the web. On this reading of the report, webpages that have a high impact as measured by PageRank are supposed to be important webpages in a sense of importance that is not reducible to mere impact or popularity. In this paper, we look at the state of the art regarding the more precise statement of the thesis that PageRank and other similar in-link-based ranking algorithms can be justified by reference to the wisdom of crowds. We argue that neither the influential preferential attachment models due to Barabási and Albert in (Science 286:509-512, 1999) nor the recent model introduced by Masterton et al. in (Scientometrics 106:945-966, 2016) allows for a satisfactory wisdom-of-crowds justification of PageRank. As a remedy, we suggest that future work should explore "dual models" of linking on the web, i.e., models that combine the two previous approaches. Dual models view links as being attracted to both popularity and importance. [ABSTRACT FROM AUTHOR]

Background: The Secondary Prevention in Uppsala Primary Healthcare Project (SUPRIM) is a prospective randomized controlled trial of a group-based cognitive behavioral therapy (CBT) stress management program for coronary heart disease (CHD) patients. The intervention reduced the risk of fatal or non-fatal first recurrent cardiovascular (CV) events. The aim of the present study was to analyze if the positive effects of the CBT program on clinical outcomes could have been mediated by changes in biomarkers for inflammation. Methods: Altogether 362 patients with CHD were randomly assigned to intervention or usual care. The inflammatory biomarkers (VCAM-1, TNF-R1, TNF-R2, PTX3, and hs-CRP) were serially assessed at five time points every six months from study start until 24 months later, and analyzed with linear mixed models. Results: Baseline levels of the inflammatory markers were near normal, indicating a stable phase. The group-based CBT stress management program did not significantly affect the levels of inflammatory biomarkers in patients with CHD. Three out of five (VCAM-1, TNF-R2, and PTX3) inflammatory biomarkers showed a slight increase over time in both study groups, and all were positively associated with age. Conclusion: Group-based CBT stress management did not affect biomarkers for inflammation in patients with CHD. It is therefore unlikely that inflammatory processes including these biomarkers were mediating the effect the CBT program had on the reduction in CV events. The close to normal baseline levels of the biomarkers and the lack of elevated psychological distress symptoms indicate a possible floor effect which may have influenced the results. [ABSTRACT FROM AUTHOR]

The frictional behavior during powder compaction and ejection is studied using an instrumented die with eight radial sensors. The average friction over the total powder pillar is used to determine a local friction coefficient at each sensor. By comparing forces at compaction with forces at ejection, it can be shown that the Coulomb’s friction coefficient can be described as a function of normal pressure. Also stick phenomena has been investigated in order to assess its influence on the determination of the local friction coefficient. [ABSTRACT FROM AUTHOR]

Objectives The aim of the present study is to determine if the delineation of one or two optimally chosen intracranial areas (ICA) is enough to achieve adequate estimates of intracranial volume (ICV) in magnetic resonance imaging. Methods The correlations of 62 fully delineated ICVs with four types of ICV estimates were calculated. The estimate types were: (1) a single midsagittal ICA, (2) single ICA multiplied by the intracranial width perpendicular to the ICA, (3) sum of two ICAs multiplied by the perpendicular intracranial width and (4) shape-preserving piecewise cubic interpolation using two ICAs. For methods 2-4, the fully delineated ICVs were randomly separated into an evaluation and a validation set of equal size. Method 1 was validated against all of the fully delineated ICVs. [ABSTRACT FROM AUTHOR]

Much of what we believe we know, we know through the testimony of others (Coady, 1992). While there has been long-standing evidence that people are sensitive to the characteristics of the sources of testimony, for example in the context of persuasion, researchers have only recently begun to explore the wider implications of source reliability considerations for the nature of our beliefs. Likewise, much remains to be established concerning what factors influence source reliability. In this paper, we examine, both theoretically and empirically, the implications of using message content as a cue to source reliability. We present a set of experiments examining the relationship between source information and message content in people's responses to simple communications. The results show that people spontaneously revise their beliefs in the reliability of the source on the basis of the expectedness of a source's claim and, conversely, adjust message impact by perceived reliability; hence source reliability and message content have a bi-directional relationship. The implications are discussed for a variety of psychological, philosophical and political issues such as belief polarization and dual-route models of persuasion. [ABSTRACT FROM AUTHOR]

This article demonstrates how large social clubs are operating at the locus of an ethnic community-making of Swedish migrants in Southern Spain. The clubs are selectively targeting the relatively wealthy (ethnic) Swedish individuals of older age, offering them a home-like social arena 'in Swedish' in which the mediation of information and services is just one of the 'guidelines' the clubs offer to ensure the members a comfortable lifestyle in Spain. In this social space, the Swedish migrants meet, socialise and, to some extent, also consume, rather than participating and integrating in Spanish society. The article argues that the practices used by the social clubs are becoming part of the infrastructure guiding migrants towards a Swedish diasporic lifestyle in Southern Spain. [ABSTRACT FROM AUTHOR]

My concern in this paper is a debate between Pascal Engel and Richard Rorty documented in the book What's the Use of Truth? Both Engel and Rorty problematize the natural suggestion that attaining truth is a goal of our inquiries. Where Rorty thinks this means that truth is not something we should aim for at all over and beyond justification, Engel maintains that truth still plays a distinct (conceptual) role in our intellectual and daily lives. Thus, the debate between Engel and Rorty ends in a standoff. In the present paper, I question the claim that truth is not a goal of inquiry. I do so from the point of view of a systematic and general theory of rational goal-setting which has its roots in management science. I argue, in this connection, that Rorty's central claim rests on a principle of goal-setting rationality that is generally invalid. The bottom line is that the goal of truth, like other visionary goals, is likely to have the positive effect of increasing motivation and effort, and this may offset the drawbacks which Rorty, rightly, calls attention to. In largely following Rorty in this regard, Engel is making one concession too much to his opponent. [ABSTRACT FROM AUTHOR]