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Drought stress considered a key restrictive factor for a warm-season bermudagrass growth during summers in China. Genotypic variation against drought stress exists among bermudagrass (Cynodon sp.), but the selection of highly drought-tolerant germplasm is important for its growth in limited water regions and for future breeding. Our study aimed to investigate the most tolerant bermudagrass germplasm among thirteen, along latitude and longitudinal gradient under a well-watered and drought stress condition. Current study included high drought-resistant germplasm, "Tianshui" and "Linxiang", and drought-sensitive cultivars; "Zhengzhou" and "Cixian" under drought treatments along longitude and latitudinal gradients, respectively. Under water deficit conditions, the tolerant genotypes showed over-expression of a dehydrin gene cdDHN4, antioxidant genes Cu/ZnSOD and APX which leads to higher antioxidant activities to scavenge the excessive reactive oxygen species and minimizing the membrane damage. It helps in maintenance of cell membrane permeability and osmotic adjustment by producing organic osmolytes. Proline an osmolyte has the ability to keep osmotic water potential and water use efficiency high via stomatal conductance and maintain transpiration rate. It leads to optimum CO2 assimilation rate, high chlorophyll contents for photosynthesis and elongation of leaf mesophyll, palisade and thick spongy cells. Consequently, it results in elongation of leaf length, stolon and internode length; plant height and deep rooting system. The CdDHN4 gene highly expressed in "Tianshui" and "Youxian", Cu/ZnSOD gene in "Tianshui" and "Linxiang" and APX gene in "Shanxian" and "Linxiang". The genotypes "Zhongshan" and "Xiaochang" showed no gene expression under water deficit conditions. Our results indicate that turfgrass show morphological modifications firstly when subjected to drought stress; however the gene expression is directly associated and crucial for drought tolerance in bermudagrass. Hence, current research has provided excellent germplasm of drought tolerant bermudagrass for physiological and molecular study and future breeding. [ABSTRACT FROM AUTHOR]

Background: Despite reductions in dental caries experience in developed countries, early childhood caries remains the most prevalent health problem in developing countries. This has a direct impact on the oral health-related quality of life of both children and parents. The objective of this study was to examine the impact of comprehensive dental treatment under general anaesthesia on oral healthrelated quality of life in children, using a parental and caregiver perception questionnaire. Methods: A comparative cross-sectional study was conducted in the Children Hospital, Pakistan Institute of Medical Sciences, Islamabad from July to December 2015. A total of 40 children were enrolled in the study. The oral health-related quality of life questionnaire was completed by either a parent or caregiver during the initial visit and afterward in follow-up appointments, conducted 4-8 weeks after comprehensive dental treatment under general anaesthesia. Results: The mean age of all the enrolled children was 5.7±1.7 years. Among 40 children, 55% (22) were girls and 45% (18) were boys. A highly significant reduction was observed between the pre and post-treatment P-CPQ total scores from 76.9±15.8 to 13.3±9.5 with a p-value <0.0001. Regarding the P-CPQ domains, a significant reduction from the pre- to post-treatment scores was observed for oral symptoms; functional limitations, emotional well-being, and social well-being with a p-value <0.0001. Conclusion: The oral health-related quality of life was significantly improved after comprehensive dental treatment under general anaesthesia. The findings of this study may be utilized to improve future guidelines and betterment of dental health of children by health care providers and initiatives for future health programs. [ABSTRACT FROM AUTHOR]

Commercial broilers have a short production cycle and a high requirement for energy (3000 kcal/kg in starter phase and 3200 kcal/kg in finisher phase). Therefore, the need to add energy rich lipids to their diet is inevitable. Digestibility of fat depends on its multiple properties: chain length, the composition of fatty acids, ratio of saturated/unsaturated fatty acids and free fatty acids. The high cost of vegetable oils and less availability due to their consumption in human diet are the main reasons for searching for cheaper alternative fat sources. Animal oils like poultry and fish oil are the by-product of rendering plants and after refining, they are used in poultry diets as an energy source. Due to presence of impurities and free fatty acids, the digestibility of animal fat is lower. There is a limited amount of bile acids and lipase available during early age and when birds are reared on high energy diet (finisher phase). Supplementation of emulsifier or lipase in broilers' diet increase fat utilisation. Emulsifiers increase fat digestibility by increasing active surface area of lipid droplets. Lysolecithin and lysophospholipids are produced from hydrolyses of lecithin and phospholipids by phopholipase A2. The bile acids are mainly composed of cholic acid, hyodeoxycholic acid and chenodeoxycholic acid and have strong emulsification properties. Triacylglyceryl acylase (lipase) is an enzyme involved in catalysis and the hydrolysis of lipids. It can be concluded that use of emulsifier and lipase in broiler diet improves growth performance, nutrient digestibility and intestinal histology in broilers. [ABSTRACT FROM AUTHOR]

Background: Empathy is regarded as one of the leading elements of good physician-patient relationships, having a strong association with improved patient outcomes. It is an aspect of personality, which is considered to be an essential component in the development of interpersonal understanding and in assisting proficiency in communication. Developing empathy among medical students who are going to become tomorrow's physicians is an important part of medical education. The objective of this study was to measure the mean empathy score of medical students at a private medical college and identify associated factors. Methods: This cross-sectional study was conducted from January to June 2018 among 569 medical students at a private medical college in Lahore. Toronto empathy questionnaire (TEQ) was used to determine empathy levels among students. Data was analysed in IBM SPSS-20. Mean TEQ scores were calculated. Independent sample t-test and one-way ANOVA were used to determine association between mean Toronto empathy score and socio-demographic variables, significant at a p-value of <0.05. Results: The age of 569 respondents ranged from 17 to 27 years with a mean of 20.82±1.757. There were 317 (55.71%) females; and 312 (54.8%) were residing at home with parents. The overall mean TEQ score was calculated to be 42.57±7.513. The Cronbach's alpha was 0.710. There was a significant association between empathy levels and year of study of the respondents (p<0.001), gender (p<0.001) and students' permanent area of residence (p=0.018). Conclusion: Overall mean TEQ score was found to be 42.57±7.513. Statistically significant difference was found between gender, place of residence, year of study and mean empathy scores. [ABSTRACT FROM AUTHOR]

Objectives: Dental caries is among common oral conditions in children and adults. Several studies and preventive measures have been carried out over the world to reduce dental caries rate. The objective of this study was to evaluate the relationship between caries score and socioeconomic status among children. Study Design: Cross-sectional study. Setting: Primary schools of Hayatabad, Peshawar. Period: months (January to June 2019). Material and Methods: 240 children aged from 3 to 5 years old were recruited in our study from government and private schools of Hayatabad, Peshawar. Socioeconomic status of the children's parents was deduced by visiting government schools having lower fees and private schools having higher fees in Hayatabad, Peshawar. The frequency of dental caries among children was determined by clinical examination followed by decayed, extracted, filled teeth index. Results: In this study, 120 participants from private schools belonged to the upper class while the other 120 subjects from government schools belonged to the lower class. The mean DEFT value was found to be 30% greater in children of private schools. Conclusion: The study determined that the frequency of DEFT was found more in upper economic status as compared to the lower economic status, which shows association of socio-economic status with oral health condition. [ABSTRACT FROM AUTHOR]

Subcutaneous fat necrosis (SCFN) is a rare dermatologic condition which until recently was thought to occur only in term neonates. Its presentations are protean and early in the disease; it mimics other more common neonatal dermatologic conditions. Although benign, it runs a prolonged course and may be associated with some complications and therefore needs to be differentiated from other more life-threatening neonatal dermatologic conditions. We present a case of a term neonate with histology report highlighting some characteristic features of SCFN and the need to differentiate it from sclerema neonatorum (SN), a condition associated with fatal outcome. [ABSTRACT FROM AUTHOR]

Zinc and Boron dearth is an imperative soil constraint in Pakistan. Zinc (Zn) and boron (B) deficiency in soil is primary hindrance to achieve yield potential of maize. An experiment was conducted with the objectives to optimize methods of B and Zn application in maize and ultimately enhance profitability. The experiment was laid out in randomized complete block design with factorial arrangement during autumn 2015. Treatments were replicated three times. The treatments were comprised of C = no Zn and B (Control); Zn (S) = soil application of Zn @ of 12 kg ha-1; B (S): soil application of B @ 3 kg ha-1; Zn (F) = foliar application of 1% Zn at 9th leaf stage; B (F) = foliar application of 0.5% B at 9th leaf stage; Zn (S) + B (S) = soil application of Zn @ 12 kg ha-1 + B @ of 3 kg ha-1 and Zn (F) + B (F) = foliar application of 1% Zn + 0.5% B at 9 leaf stage. Foliar application of Zn and B produced more plant height, cob length, girth, stem girth, shelling percentage, number of grains per cob, 1000-grain weight, harvest index, grain and biological yield. Maximum marginal rate of return was obtained with foliar application of both Zn and B and using foliar Zn alone. Integrated B and Zn application produced more marginal rate of returns both in soil and foliar applications. Use of foliar Zn application also depicted promising results while foliar or soil B application without using Zn enhanced cost of production. [ABSTRACT FROM AUTHOR]

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Abiotic stresses are one of the major constraints to crop production and food security worldwide. The situation has aggravated due to the drastic and rapid changes in global climate. Heat and drought are undoubtedly the two most important stresses having huge impact on growth and productivity of the crops. It is very important to understand the physiological, biochemical, and ecological interventions related to these stresses for better management. A wide range of plant responses to these stresses could be generalized into morphological, physiological, and biochemical responses. Interestingly, this review provides a detailed account of plant responses to heat and drought stresses with special focus on highlighting the commonalities and differences. Crop growth and yields are negatively affected by sub-optimal water supply and abnormal temperatures due to physical damages, physiological disruptions, and biochemical changes. Both these stresses have multi-lateral impacts and therefore, complex in mechanistic action. A better understanding of plant responses to these stresses has pragmatic implication for remedies and management. A comprehensive account of conventional as well as modern approaches to deal with heat and drought stresses have also been presented here. A side-by-side critical discussion on salient responses and management strategies for these two important abiotic stresses provides a unique insight into the phenomena. A holistic approach taking into account the different management options to deal with heat and drought stress simultaneously could be a win-win approach in future. [ABSTRACT FROM AUTHOR]