Search

Background: Analysis of the survival of root‐filled posterior teeth and the associated prognostic tooth‐related factors will enable clinicians to predict the outcome of root canal treatment. Objectives: To investigate (i) the survival of root‐filled posterior teeth and (ii) the tooth‐related factors that may affect their survival. Methods: Randomized controlled trials, comparative studies and observational studies assessing survival rates of root‐filled posterior teeth with a minimum 4‐year follow‐up period were identified through an electronic search of the following databases up to January 2023: The Cochrane Central Register of Controlled Trials, Medline via PubMed, the Cochrane Database of Systematic Reviews, Embase, Web of Science and NIHR centre for reviews and dissemination. Two reviewers (SP and ML) independently selected the final studies based on pre‐defined inclusion criteria. The Newcastle Ottawa Scale and the Cochrane Risk of Bias Tool for Randomized Trials were used to assess the risk of bias. Pooled weighted survival rates were analysed using a random effects meta‐analysis model using DerSimonean and Laird methods. Descriptive analysis of studies describing any prognostic tooth‐related factors was conducted. Results: Of the 72 studies identified, data from 20 studies were included in the survival meta‐analysis, and data from 13 of these studies were included in the descriptive analysis of tooth‐related factors; 12 studies were retrospective, 7 were prospective, and one was a randomized control trial. The pooled survival rates at 4–7 years and 8–20 years of root‐filled posterior teeth regardless of tooth type was 91% (95% CI, 0.85; 0.95) and 87% (95% CI, 0.77; 0.93), respectively. The prognostic tooth‐related factors mentioned in the included studies were (i) remaining coronal tooth structure, (ii) ferrule, (iii) crown‐to‐root ratio (iv) tooth type and location (v) periodontal disease (vi) proximal contacts and (vii) cracks. Conclusions: The meta‐analysis suggests that root canal treatment has a high medium to long term survival outcome. The narrative summary identified 7 factors that affect tooth survival. However, there is a paucity of evidence, and more research is needed in this area. Registration: PROSPERO Registration: CRD42021227213. [ABSTRACT FROM AUTHOR]

Copyright of Arab Universities Journal of Agricultural Sciences is the property of Arab Universities Union of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The starting oxazolone 1 was reacted with p-aminophenol in glacial acetic acid to afford imidazolone 2, which afforded Mannich base 3 via the reaction with piperidine and paraformaldehyde. Moreover, the reaction of 2 with ethylchloroacetate or chloroacetic acid in dry acetone gave the corresponding imidazolones 4 and 5, respectively. Compound 4 reacted with benzylamine or 4-chlorobenzaldehyde to furnish 6 and 7, respectively. On the other hand, oxazolone 1 reacted with hydrazines in glacial acetic acid to afford the 1,2,4-triazines 11–15. Representative compounds of the synthesized products were established and evaluated as antioxidant and corrosion inhibitors for gasoline lube oils. [ABSTRACT FROM PUBLISHER]

2-[2-(1,3-Diphenyl-1H-pyrazol-4-yl)-vinyl]-benzo[d][1,3]oxazin-4-one (2) was utilized as a key intermediate for the synthesis of some new quinazolinone derivatives incorporating diphenylpyrazole moiety. Treatment of benzoxazine derivative 2 with different amines, namely, p-phenylenediamine, p-anisidine, p-toluidine, sodiumazide, hydroxylamine hydrochloride, phenyl hydrazine, and hydrazine hydrate afforded pyrazolyl quinazoline derivatives 3, 4, 5, 6, 7, 9, and 10, respectively. Structure 10 was undergoing acetylation and benzoylation with acetic anhydride or benzoyl chloride to afford 11 and 12, respectively. Representative compounds of the synthesized products were established and evaluated as antioxidant and corrosion inhibitors for gasoline lube oils. [ABSTRACT FROM AUTHOR]

2-Phenyl-4-thienylidene-2-oxazolin-5-one I was prepared and reacted with 2-aminothiazole, p-aminophenol, and p-aminoacetophenone in the presence of acetic acid containing catalytic amounts of freshly fused sodium acetate to give the corresponding imidazolone derivatives II, III, and IV, respectively. A Claisen reaction of IV with ethylacetate gave the corresponding imidazolone V, which on reaction with phenylhydrazine in ethanol afforded the corresponding pyrazolinoimidazolone VI. On the other hand, I reacted with o- and p-phenylenediamines in ethanol and yielded the corresponding o- and p-aminophenylcarboxamide of α-phenyl carboxamido-β-thiophenoacrylic acids VII and VIII, respectively. The prepared products were evaluated as antioxidant additives for Egyptian lube oils. Some of these products showed good results. [ABSTRACT FROM AUTHOR]