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Many forms of memory exist embedded within the processes and tasks of an organization or community. Memory in the small, or memory utilized in the performance of an institutionally important task, serves as an effective task support mechanism. By basing memory on tasks (and basing task support on memory), memory systems can provide additional and necessary support services for organizations and communities. As an example of memory in the small, in this article we describe a software system, called the ASSIST, that combines memory with task performance for a scientific community. The ASSIST utilizes and stores the collective memory of astrophysicists about data analysis, and is used worldwide by astrophysicists. In this article, we also consider the architectural and theoretical issues involved when combining memory with task performance. [ABSTRACT FROM AUTHOR]

To identify previously unrecognized sources for acquiring acute hepatitis B and non-A, non-B (NANB) hepatitis, we interviewed patients with these types of hepatitis who were reported to two county health departments in the United States and matched control subjects for known and potential risk factors for acquiring hepatitis. Of 218 patients with hepatitis B and 140 patients with NANB hepatitis, 46% and 53%, respectively, had no commonly recognized source for infection. When these patients were compared with control subjects, significantly more patients with hepatitis B had multiple heterosexual partners, accounting for 14% of all hepatitis B infections; more patients with NANB hepatitis either had sexual or household contact with a person who had hepatitis in the past or had multiple heterosexual partners, accounting for 11% of all NANB infections. This is the first study to suggest that heterosexual transmission may play an important role in the spread of NANB hepatitis. [ABSTRACT FROM AUTHOR]

Objective: To define the epidemiology and clinical manifestations of hepatitis D virus infection in an institutionalized population.Design: A case-control study of hepatitis B carriers with and without serologic evidence of hepatitis D virus infection. Demographic, institutional, and medical data were obtained through questionnaires and chart review. Clinical status was assessed by liver function assays.Setting: Thirteen Illinois state facilities for the developmentally disabled.Participants: Clients (238) who were hepatitis B carriers.Results: Antibody to hepatitis D virus (anti-HDV) was detected in 71 of 238 (30%) hepatitis B carriers. Nine of thirteen facilities housed positive clients. Previous residence at one facility, designated B, was the strongest correlate of anti-HDV positivity; 85% of positive persons had lived there compared with 16% of negative controls (odds ratio 28.3 [95% CI, 13.2 to 60.7], P less than 0.001). Past hepatitis episodes were more common among anti-HDV-positive clients (37% compared with 7%) (odds ratio, 7.5 [95% CI, 3.0 to 19.1], P less than 0.001) and occurred mainly at facility B from 1950 to 1975. Liver function tests were infrequently abnormal among anti-HDV-positive clients.Conclusions: Results show widespread hepatitis D virus infection in our institutionalized population and suggest that transmission occurred mainly in the past at the overcrowded facility B. The low prevalence of laboratory evidence of chronic liver disease in the anti-HDV-positive clients may be explained by increased mortality among those originally infected from 1950 to 1975. [ABSTRACT FROM AUTHOR]

The article reports on the use of chlorhexidine gluconate in the prevention of bone resorption in rats. A study was conducted on rats which were swabbed daily with a 2% chlorhexidine solution on dental plaque accumulations over a period of 60 days. It was found that the chlorhexidine reduced the amount of plaque and the loss of alveolar bone.