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Punch grafting is a technique that can improve and accelerate the healing of hard-to-heal wounds and reduce the associated pain. It is a simple and inexpensive procedure that can be performed in the examination room. It is a technique that uses small split-thickness skin grafts (STSG) to promote the growth of epithelial tissue. It has been described as being used mainly to treat ulcers of venous, arterial, hypertensive and diabetic aetiology. Punch grafting has also been used successfully in postoperative dermatological surgical wounds. This article describes and details the performance of the punch-graft technique, with special emphasis on aftercare and the role of nurses in the procedure. A clinical case is presented of a patient who underwent surgery for cutaneous squamous cell carcinoma and whose primary closure was rejected. It was decided to place the STSGs obtained from the anterior aspect of the patient's thigh after preparation of the recipient area to ensure an optimal wound bed. The patient's pain subsided within a few days, and the wound healed within weeks with weekly dressing changes. [ABSTRACT FROM AUTHOR]

Primary localized cutaneous nodular amyloidosis (PLCNA) is included in the primary forms of cutaneous amyloidosis along with macular and lichenoid amyloidosis. It is a rare disease attributed to plasma cell proliferation and deposition of immunoglobulin light chains in the skin. We present the case of a 75-year-old woman with a personal history of Sjogren's syndrome (SjS), who consulted for asymptomatic yellowish, waxy nodules on the left leg. Dermoscopy of the lesions showed a smooth, structureless, yellowish surface with hemorrhagic areas and few telangiectatic vessels. Histopathology revealed an atrophic epidermis and deposits of amorphous eosinophilic material in the dermis with a positive Congo red stain. The diagnosis of nodular amyloidosis was made. Periodic reevaluation was indicated after the exclusion of systemic amyloidosis. PLCNA is often associated with autoimmune connective tissue diseases, and up to 25% of all PLCNA cases occur in patients with SjS. Therefore, in addition to ruling out systemic amyloidosis, screening for possible underlying SjS should be performed when the diagnosis of PLCNA is confirmed. [ABSTRACT FROM AUTHOR]

Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare condition attributed to plasma cell proliferation and the deposition of immunoglobulin light chains in the skin without association with systemic amyloidosis or hematological dyscrasias. It is not uncommon for patients diagnosed with PLCNA to also suffer from other auto-immune connective tissue diseases, with Sjögren's syndrome (SjS) showing the strongest association. This article provides a literature review and descriptive analysis to better understand the unique relationship between these two entities. To date, 34 patients with PLCNA and SjS have been reported in a total of 26 articles. The co-existence of PLCNA and SjS has been reported, especially in female patients in their seventh decade of life with nodular lesions on the trunk and/or lower extremities. Acral and facial localization, which is a typical localization of PLCNA in the absence of SjS, seems to be much more unusual in patients with associated SjS. [ABSTRACT FROM AUTHOR]

This article discusses a case study of a 61-year-old woman with systemic mastocytosis and hypereosinophilia who presented with symptoms of tachycardia, severe hypotension, and nausea. The patient had splinter hemorrhages, which are dark, non-bleachable subungual lesions caused by disruption of the nail bed's spiral arteries. While splinter hemorrhages are commonly associated with infective endocarditis, they can also occur in other conditions such as psoriasis, lichen planus, or connective tissue disorders. The authors suggest that in this particular case, the excess of mast cells in systemic mastocytosis may have contributed to the development of splinter hemorrhages, in addition to eosinophilia. [Extracted from the article]

Allergic contact dermatitis caused by herbicide containing glyphosate-isopropylamine salt After reviewing the literature, we have found only two cases of glyphosate ACD in a series of pesticide patch tests among banana plantation workers.[9] Therefore, ACD caused by glyphosate appears to be extremely rare. Keywords: allergic contact dermatitis; CAS no. 38641-94-0; case report; farmer; glyphosate-isopropylamine; herbicide EN allergic contact dermatitis CAS no. 38641-94-0 case report farmer glyphosate-isopropylamine herbicide 230 232 3 02/08/23 20230301 NES 230301 CASE REPORT A 57-year-old male farmer with no known relevant medical history was referred to our outpatient dermatology clinic with a widespread eruption of 2 months' duration that started on the arms 3 days after occupational exposure to Glyfoon (Agrolac, Barcelona, Spain) containing glyphosate-isopropylamine salt. [Extracted from the article]

Photodynamic therapy (PDT) is an effective treatment option for the treatment of superficial basal cell carcinoma (sBCC). Recent publications have demonstrated that PDT with 7.8% 5‐aminolaevulinic acid nanoemulsion‐based gel (BF‐200 ALA‐PDT) is an effective and safe alternative for the treatment of sBCC). To investigate the efficacy and safety of 7.8% 5‐aminolaevulinic acid nanoemulsion‐based gel (BF‐200 ALA)‐PDT for the treatment of sBCC. A non‐controlled, open‐label single centre study was conducted. Patients received one PDT cycle with two PDT sessions one‐week apart. In case that clinical‐dermoscopy evaluation of treatment outcome revealed remaining lesions, a second PDT cycle was performed. The clinical results at the dermoscopy and fluorescence diagnosis level were histologically confirmed in all patients. Treatment response was evaluated 3, 6, and 12 months after last PDT session. A total of 31 patients (12 men and 19 women), with a median age of 63.74 years were included in this study. 3‐month after PDT‐session, 23/31 patients were complete responders (74.19%) after two BF‐200 ALA ‐PDT sessions. Esthetic outcome was considered good‐to‐excellent. 5 Aminolevulinic acid 7.8% nanoemulsion‐based gel (BF‐200 ALA) PDT is an effective therapy option for the treatment of sBCC. Complete clearance rates were higher in those patients who received only one PDT cycle. These results show a similar tendency as shown in other publications. [ABSTRACT FROM AUTHOR]

Case report, atopic dermatitis, head and neck dermatitis, surfactants, decyl glucoside, dupilumab, CAS n° 58846-77-8 Refractory Head and Neck atopic dermatitis pattern treated with Dupilumab: Allergic contact dermatitis caused by decyl glucoside. Decyl glucoside (and lauryl glucoside) is the third most prevalent allergen surfactant group. [Extracted from the article]

The results were suspicious of a non-eczematous contact dermatitis caused by I Morus nigra i L. Prick-by-prick test result with I M nigra i L. fruit and leaf was negative. Keywords: case report; lichenoid contact dermatitis; Morus nigra L. EN case report lichenoid contact dermatitis Morus nigra L. 484 486 3 05/06/21 20210601 NES 210601 Frequently, contact dermatitis presents with non-eczematous features, such as erythema multiforme-like, purpuric, pigmented kinds of, or lichenoid eruption. [Extracted from the article]

This letter to the editor discusses a case of high-risk squamous cell carcinoma (SCC) in an 88-year-old woman with a history of chronic sun exposure. The tumor had grown to a size of 8.9 × 5.7 cm and required surgery under general anesthesia. The surgical challenge was to remove the lesion with safety margins and reconstruct the secondary defect. The patient underwent successful surgery and had no complications or signs of recurrence. The article also highlights the increasing global incidence of SCC and the impact of delays in diagnosis and treatment due to the COVID-19 pandemic. It emphasizes the importance of early detection and the factors that influence prognosis and the need for adjuvant therapy in high-risk SCC cases. [Extracted from the article]

Airborne, allergic contact dermatitis, CAS no. 203313-25-1 Movento 150, case report, farming, pesticide, phytosanitary, spirotetramat Up to 40% of patients show positive patch test results.4 Airborne pattern or hand/facial dermatitis in farmers should be notified as contact dermatitis. Keywords: airborne; allergic contact dermatitis; CAS no. 203313-25-1 Movento 150; case report; farming; pesticide; phytosanitary; spirotetramat EN airborne allergic contact dermatitis CAS no. 203313-25-1 Movento 150 case report farming pesticide phytosanitary spirotetramat 99 100 2 06/17/21 20210701 NES 210701 CASE REPORT A 72-year-old man was referred to our contact eczema department complaining of pruritic eczematous rash lasting 6 months. [Extracted from the article]

Androgenetic alopecia (AGA) is an androgen-dependent process and represents the most frequent non-scarring alopecia. Treatments for AGA do not always achieve a satisfactory result for the patient, and sometimes cause side effects that lead to discontinuation of treatment. AGA therapeutics currently includes topical and oral drugs, as well as follicular unit micro-transplantation techniques. Tissue engineering (TE) is postulated as one of the possible future solutions to the problem and aims to develop fully functional hair follicles that maintain their cyclic rhythm in a physiological manner. However, despite its great potential, reconstitution of fully functional hair follicles is still a challenge to overcome and the knowledge gained of the key processes in hair follicle morphogenesis and biology has not yet been translated into effective replacement therapies in clinical practice. To achieve this, it is necessary to research and develop new approaches, techniques and biomaterials. In this review, present and emerging hair follicle bioengineering strategies are evaluated. The current problems of these bioengineering techniques are discussed, as well as the advantages and disadvantages, and the future prospects for the field of TE and successful hair follicle regeneration. [ABSTRACT FROM AUTHOR]