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Around 1840, a gold coin was discovered near Radoboj (northwestern Croatia), a Celtic imitation of a gold stater of Alexander III of type Athena/Nike. In 2019, during archaeological excavation of the Roman temple at Frauenberg, near Leibnitz (Austria), two imitations of staters of the same type were excavated. Of these, one coin was minted with the same dies for obverse and reverse as the coin from Radoboj, which undoubtedly testifies to minting in the same mint. In the area of north-western Croatia and eastern Slovenia, four other Athena/Nike staters can be documented at four other sites. To date, 83 Athena/Nike imitations have been discovered in Central Europe, of which 32 coins originate from 26 sites. Seven coins from six sites in the area south of the middle course of the Mura and Drava rivers therefore significantly complement the current record of finds of these earliest Celtic coin finds in Central Europe. At the same time, it proves that the minting of this group of imitations can be attributed to the local Celtic tribes sometime in the middle of the 3rd century BC. [ABSTRACT FROM AUTHOR]

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Background: Translational medicine requires the integration of knowledge using heterogeneous data from health care to the life sciences. Here, we describe a collaborative effort to produce a prototype Translational Medicine Knowledge Base (TMKB) capable of answering questions relating to clinical practice and pharmaceutical drug discovery. Results: We developed the Translational Medicine Ontology (TMO) as a unifying ontology to integrate chemical, genomic and proteomic data with disease, treatment, and electronic health records. We demonstrate the use of Semantic Web technologies in the integration of patient and biomedical data, and reveal how such a knowledge base can aid physicians in providing tailored patient care and facilitate the recruitment of patients into active clinical trials. Thus, patients, physicians and researchers may explore the knowledge base to better understand therapeutic options, efficacy, and mechanisms of action. Conclusions: This work takes an important step in using Semantic Web technologies to facilitate integration of relevant, distributed, external sources and progress towards a computational platform to support personalized medicine. [ABSTRACT FROM AUTHOR]

The short SRT nitrification process/flowsheet was developed to provide an inexpensive alternative for plants in the northern climates which need to upgrade their activated sludge process for year-round nitrification or nitrogen removal. In this process/flowsheet supplemental nitrifiers are added daily to the activated sludge process to replenish nitrifiers removed with the wasted activated sludge. The supplemental nitrifiers are grown in a separate small side-stream aeration tank using ammonia available in the digested sludge dewatering liquid or in the digester supernatant. Paper presents description of this flowsheet, the theoretical background and results of modeling. Modeling of this process/flowsheet showed that the addition of the supplemental nitrifiers allows the main stream activated sludge process to nitrify during low winter temperatures at very low SRT values. For example an SRT of 7 to 10 days at 10°C is required, instead of 13 to 18 days for conventional nitrification. Thus this process/flowsheet can provide nitrification in a substantially smaller aeration tank than required for the conventional nitrification. [ABSTRACT FROM AUTHOR]

An abstract of the article "The FtsH protease is required for the repair of Photosystem II in the cyanbacterium Synechocystis 6803 damaged UV-B radiation," by Otilia Cheregiis and colleagues is presented.