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The scientific literature is increasingly focused on peri-implant mucositis and peri-implantitis, which are biological outcomes of dental implant treatment. Background/Objectives: The present study aimed to evaluate the two most critical complications of dental implantation, peri-implant mucositis and peri-implantitis, through the prism of different influencing factors. Methods: We followed 40 patients, with a total number of 92 dental implants, divided into three age groups: under 35 years, between 35 and 55 years, and older than 55 years. Patients were also divided into groups according to the time since implant placement: 1–3 years, 4–7 years, and more than 7 years. The patients were examined, and periodontal pocket depth, peri-implant pocket depth, Löe–Silness gingival index, mucosal thickness, and keratinized mucosal width were recorded; bone resorption was measured on radiographs using a 2D image analysis method; and a questionnaire was also conducted. Results: Bone resorption was highest in the 35–55 age group (3.09 ± 0.04 mm) and for implants placed 4–7 years ago (3.39 ± 0.12 mm). Females had a mean bone resorption of 3.4 ± 0.15 mm and males of 2.45 ± 0.07 mm. Statistically, there was a significant difference only in the Löe–Silness index: the 35–55 age group had the highest values (p = 0.04). Conclusions: There were no statistically significant differences between the time since implant placement and the degree of bone resorption, nor between sexes. Peri-implant inflammation may occur at any age, regardless of the lifetime of the implants. [ABSTRACT FROM AUTHOR]

Background: The purpose of this study was to investigate the effect of different light curing modes on the polymerization shrinkage of a bulk-fill composite and to evaluate the impact of two layering techniques on the cuspal deflection. Methods: Nine different light curing modes were tested on bulk-fill composite samples in aluminum MOD cavities. Intensity, duration, and illumination distance were the factors that changed during the different curing modes. The digital image correlation method was used to visually represent the displacement of carbon particles on the materials' surface caused by shrinkage along both the horizontal and vertical axes. For simulating cuspal deflection, a separate protocol was used, with a bulk and horizontal layering technique. Results: The results showed that the largest horizontal displacements were present in the soft start group (6.00 ± 0.82 µm) and in the X-tra power group (5.67 ± 1.21 µm). The smallest horizontal displacements were detected in normal curing modes (4.00 ± 1.58 µm; 4.00 ± 2.68 µm). The largest vertical displacements, at the bottom layer, were present in the normal curing mode group with a 20 s curing time (5.22 ± 1.56 µm), while the smallest vertical displacements were shown in the X-tra power group (2.89 ± 0.60 µm). The observed particle displacements showing the shrinkage of the composite were correlated with the curing mode. The bulk-fill group showed less cuspal deflection than the horizontal layering group did, but the difference was not statistically significant (p = 0.575). Conclusions: Within the limitations of this in vitro study, it can be concluded that lower intensities of curing lights (1200 mW/cm2) may perform better from the point of view of material shrinkage than high and extreme light intensities do. The pulse delay mode might be recommended in the case of bulk-fill materials. The number of layers did not significantly affect the cuspal deflection in the case of the studied composite. [ABSTRACT FROM AUTHOR]

This article explores the relationship between genetic variations and dental variations in individuals with and without tooth agenesis. Specifically, the study focuses on the correlation between morphological variations of the upper first permanent molars and genetic variants of the MSX1 gene. The results indicate that individuals without the gene mutation are more likely to have larger Carabelli cusps. Additionally, the study found that Carabelli cusps are more common in men and that men tend to have larger cusps compared to women. This research provides valuable insights into the genetic factors that contribute to dental variations. [Extracted from the article]

(1) Background: Hypodontia has a multifactorial aetiology, in which genetic factors are a major component. Associated with this congenital absence, the formed teeth may show differences in size and shape, which may vary with the specific genetic variants and with the location of the missing teeth. The aims of the present study were to investigate a specific variant of MSX1, derive morphometric tooth measurements in a sample of patients with isolated maxillary lateral incisor agenesis and matched controls, and model the findings. (2) Methods: Genotyping of the MSX1 rs8670 genetic variant and morphometric measurements with a 2D image analysis method were performed for 26 hypodontia patients and 26 matched controls. (3) Results: The risk of upper lateral incisor agenesis was 6.9 times higher when the T allele was present. The morphometric parameters showed significant differences between hypodontia patients and controls and between the unilateral and bilateral agenesis cases. The most affected crown dimension in the hypodontia patients was the bucco-lingual dimension. In crown shape there was significant variation the Carabelli trait in upper first molars. (4) Conclusions: The MSX1 rs8670 variant was associated with variations in morphological outcomes. The new findings for compensatory interactions between the maxillary incisors indicate that epigenetic and environmental factors interact with this genetic variant. A single-level directional complex interactive network model incorporates the variations seen in this study. [ABSTRACT FROM AUTHOR]

Background: The esthetic proportion gauge developed by Chu is using a 78% recurring esthetic dental (RED) proportion and it is based on evaluating the size and proportion of frontal teeth chairside. The aim of the present study was to evaluate the validity of Chu's device and to measure the correlation between the width and length of the frontal teeth, attempting to identify the application of the proportion gauge in Mureș county. Materials and methods: From the 142 selected patients, 73 fulfilled the inclusion criteria. The height and width values of the participants' teeth were measured with a digital caliper and evaluated with Chu's esthetic proportion gauge. The measurements were then compared statistically. Results: The values obtained from the digital caliper measurements did not correlate with Chu's proportion scale, and the results showed no significant differences between the two sides (p >0.05). Conclusions: In conclusion, the measured teeth ratios did not show a similarity with the predetermined esthetic proportion scale suggested by Chu. [ABSTRACT FROM AUTHOR]

Copyright of Hungarian Medical Journal / Orvosi Hetilap is the property of Akademiai Kiado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Currently available direct restoration materials have been developed to have improved optical properties to interact with light in the same manner as the natural tooth. The objective of this study was to investigate the fluorescence of different enamel resin composites. In the present study, nine brands of enamel composites were tested in vitro, some of which are cited by manufacturers as having color adjustment potential. Fluorescence spectra of the composite specimens and the human natural enamel were measured with a fluorescence spectrophotometer immediately after preparation and after 6 months. Qualitative data of the specimens were also collected. Statistical analyses were conducted by Kruskal–Wallis and Mann–Whitney U nonparametric tests (p < 0.05). Almost all tested resin composites presented a significant decrease in the fluorescence values after a period of 6 months. There was no significant decrease in fluorescence in the case of Harmonize™ resin composite samples, which presented the lowest initial fluorescence values. The highest value in the reduction of the initial fluorescence intensity after 6 months (22.95%) was observed for the Charisma® specimens. Composites with a color adjustment did not perform significantly better than other composites in terms of reduction in fluorescence intensity. [ABSTRACT FROM AUTHOR]

Background: The most common dental materials are resin composite direct restorative materials and dentin adhesives, which are marketed with different techniques, application recommendations, and compositions, making it difficult to choose the most suitable material and method for different cases. The present study aimed to investigate mechanical properties of teeth restored with universal and bulk-fill composites, by using different dentin adhesives and techniques, under in vitro conditions. Material and methods: The study was carried out on freshly extracted premolar and molar teeth. After cavity preparation, the teeth were restored with conventional and bulk-fill resin composites, using different adhesive techniques. To assess the effect of the cavity preparation, the direct restoration, and the adhesive protocol on the tooth structure, a transillumination method and Vickers' microhardness measurements were carried out. Results: The universal composite showed an average hardness of 55.35 HV at the occlusal level of the restoration, while the bulk-fill composite showed an average of 79.93 HV at the same level. A statistically significant difference was found between the hardness values of the two composites (p = 0.02). The transillumination test revealed micro-fissures in the tooth structure in the first phase after cavity preparation and also after polymerization. Conclusions: The bulk-fill composite showed higher hardness values than the universal composite. The tested dentin adhesives did not significantly affect the hardness of the dentin at the level of the adhesive interface. Fissures can appear in any phase of the direct restoration, after cavity preparation and polymerization. [ABSTRACT FROM AUTHOR]

Introduction: In our modern society, burnout syndrome develops over a long period of time because of constant stress and increased emotional pressure. Dentistry is known as one of the most stressful professions. The aim of this study was to determine the incidence of burnout syndrome among dentists in Mureș County, Romania, and to assess the determining factors associated with burnout. Material and methods: We conducted an online survey regarding burn-out syndrome among dentists. Results: The most frequent complaint among respondents was the loss of personal accomplishment, followed by emotional exhaustion and depersonalization. Higher levels of emotional exhaustion and depersonalization were seen in non-married, male dentists between 51–60 years, who worked more than 8 hours a day without an assistant. Conclusions: Based on the presented data, the risk factors for burnout syndrome should be brought to the attention of dentists and various preventive programs should be implemented. [ABSTRACT FROM AUTHOR]

Background: Allergy is one of the most widespread diseases in this century. Allergy-causing materials used in dentistry are most frequently metals, such as nickel, cobalt, palladium, and amalgam, certain components of dental composites, denture resin materials, and even certain mouthwash components. The aim of this study was to assess dentists' experience regarding allergies occurring in their practice among patients and among dental team members. Material and methods: We conducted a questionnaire-based study, in which 104 dentists responded. Results: Immediate allergic reactions were more often caused by different drugs, detergents, and anesthetics, while delayed allergic reactions were mostly caused by acrylates. Allergic reactions occurred more often among women than men, but the difference was not statistically significant (p = 0.3). Conclusions: Our results suggest that allergies in dentistry appear mainly among adults, caused mostly by acrylates, metals, and different drugs. Immediate allergic reactions are often present, and mostly women are susceptible to allergies. [ABSTRACT FROM AUTHOR]

The etiology of hypodontia is complex, in which both genetic and environmental factors can be related. The main objective of our study was to contribute to elucidating the genetic background of nonsyndromic hypodontia (NSH). In this order, we selected 97 NSH subjects (70 females and 27 males) from patients referred to orthodontic treatment, and we matched to each NSH subject a control by age and sex. DNA was obtained from epithelial cells from the oral mucosa. Genotyping of the PAX9 (rs4904155 and rs61754301), MSX1 (rs8670 and rs12532), and AXIN2 (rs2240308) SNPs was performed by using TaqMan SNP Genotyping Assays on a real-time PCR system. Single-nucleotide polymorphisms (SNPs) were studied for the whole NSH group and for frontal and lateral agenesis NSH subjects separately. Our results showed that the variant genotype (p=0.0008, OR = 2.9, 95% CI = 1.58–5.3) and variant T allele (p=0.0002, OR = 2.65, 95% CI = 1.6–4.39) of the MSX1 rs8670 SNP increased the risk of hypodontia in the studied population when the whole NSH group was compared with controls. The variant genotype of the MSX1 rs8670 SNP was the most frequent in frontal agenesis; meanwhile in the lateral agenesis NSH group, the AXIN2 rs2240308 SNP showed a higher frequency of the variant genotype, with a trend towards statistical significance. In conclusion, the results of the present study showed that the variant genotype and variant T allele of the MSX1 rs8670 SNP increased the risk of hypodontia in the studied population. The presence of the variant A allele of AXIN2 rs2240308 is associated with frontal agenesis but not with lateral agenesis. [ABSTRACT FROM AUTHOR]

Copyright of Hungarian Medical Journal / Orvosi Hetilap is the property of Akademiai Kiado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Measurement-based studies are prone to measurement errors, which occur at the same operator or between different operators during repeated measurements of the same sample. Aim of the study: To assess the inter-operator reliability of morphometric measurements using a bidimensional image analysis method. Material and methods: Eight study models have been selected, images of teeth and models were taken from vestibular and occlusal view. The following parameters were measured individually by three, previously trained operators: mesio-distal, occluso-gingival, and vestibulo-oral dimensions, vestibular and occlusal area, depth of palatal arch, arch breadth, arch circumference, and arch length. Intraclass correlation coefficients were calculated for each measurement. Results: The reliability of the measurements showed high degrees, all values being higher than 0.8. Conclusions: Dental morphometric measurements done by 2D image analysis can be performed by multiple operators with an excellent reliability. [ABSTRACT FROM AUTHOR]

Copyright of Hungarian Medical Journal / Orvosi Hetilap is the property of Akademiai Kiado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Hungarian Medical Journal / Orvosi Hetilap is the property of Akademiai Kiado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Epidemiological studies have reported an increasing prevalence of tooth wear, and general dental practitioners see a greater number of patients seeking treatment with worn dentition. Improper oral hygiene, unhealthy habits, occupational hazards, and potentially erosive processed foods seem to play a major role in the non-carious loss of dental hard tissue. The aim of this study is to assess the factors and cofactors that may play a major role in the genesis of dental attrition, dental abrasion, and, especially, dental erosion. Material and methods: Seventy-nine consecutive patients, aged between 17 and 78 years, have enrolled in our study, completing a questionnaire regarding chronic illnesses, eating habits, and dental hygiene, followed by a dental clinical examination. Results: The male-female ratio was 1.4:1, with a mean age of 35.6 years. Forty-four (55.7%) patients presented objective signs of tooth wear. Regarding oral hygiene habits, the use of a hard toothbrush is linked to increased tooth wear, while brushing in a circular motion seems to be the least abrasive. We found a considerable prevalence of bruxism (19%), which led to severe generalized attrition in almost half of such patients. The most popular drinks with erosive potential were coffee (58.2%), soft drinks (57%), and tea (24.1%), and extrinsic erosion was more frequent in patients younger than 30 years. Understandably, physiological tooth wear was more common in older patients. The questionnaire revealed that over 60% of patients have inaccurate knowledge of tooth wear. Conclusions: Tooth wear is partially a progressive physiological process. Unfortunately, we see it increasing in younger patients due to pathological influencing factors. These include improper tooth brushing technique and materials, bruxism, dental prosthesis, dietary habits. Primordial and primary prevention is the key to reducing morbidity, health education being an essential part of it. [ABSTRACT FROM AUTHOR]

Objectives. The role was studied of multiple single nucleotide polymorphisms in tooth agenesis in the Hungarian population using a complex approach. Methods. Eight SNPs, PAX9 -912 C/T, PAX9 -1031 A/G, MSX1 3755 A/G, FGFR1 T/C rs881301, IRF6 T/C rs764093, AXIN2-8150 A/G, AXIN2-8434 A/G and AXIN2-30224 C/T, were studied in 192 hypodontia and 17 oligodontia cases and in 260 healthy volunteers. Case-control analysis was performed to test both allelic and genotypic associations as well as associations at the level of haplotypes. Multivariate exploratory Bayesian network-based multi-level analysis of relevance (BN-BMLA) as well as logistic regression analysis were performed. Results. Conventional statistics showed that PAX9 SNP -912 C/T and the MSX1 SNP changed the incidence of hypodontia, although after Bonferroni correction for multiple hypothesis testing, the effects were only borderline tendencies. Using a statistical analysis better suited for handling multiple hypotheses, the BN-BMLA, PAX9 SNPs clearly showed a synergistic effect. This was confirmed by other multivariate analyses and it remained significant after corrections for multiple hypothesis testing ( p < 0.0025). The PAX9-1031-A- PAX9-912-T haplotype was the most relevant combination causing hypodontia. Interaction was weaker between PAX9 and MSX1, while other SNPs had no joint effect on hypodontia. Conclusion. This complex analysis shows the important role of PAX9 and MSX1 SNPs and of their interactions in tooth agenesis, while IRF6, FGFR1 and AXIN2 SNPs had no detectable role in the Hungarian population. These results also reveal that risk factors in hypodontia need to be identified in various populations, since there is considerable variability among them. [ABSTRACT FROM AUTHOR]

Copyright of dentalTarget is the property of dentalTarget and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of dentalTarget is the property of dentalTarget and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of dentalTarget is the property of dentalTarget and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)