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The fatigue of pilots is the most threatening factor in aviation safety internationally, requiring continuous management. In order to prevent aircraft accidents that may occur due to fatigue, this paper analyzes fatigue-related accident cases and previous research and suggests ways to improve the fatigue management of pilots. Problems in major fatigue accidents were active communication failure, lack of leadership of the captain, inadequate contingency management, lack of workload management, and the most important factors in accidents were inadequate decision making of continuing an approach without going around. It is necessary to proactively improve and establish go-around culture in the organization and manage human factors with training and procedures of Threat and Error Management and Crew Resource Management. In order to fundamentally prevent accidents related to fatigue fundamentally, it is necessary to establish Fatigue Risk Management and Safety Management System, and identify the actual threats and errors in the cockpit of the aircraft. [ABSTRACT FROM AUTHOR]

Purpose: The COVID-19 pandemic has wide spread to aviation. This study was conducted to find out the perception of flight training for student pilots in the flight training center in a university with COVID-19 pandemic. Methods: It analyzed through qualitative research by aviation subject matter experts in Korea. Results: The advantages of COVID-19 were the increased flight training opportunities due to significant decrease of aircraft operations in the airports, reduced ground school hours due to Social Distancing concerns of infection, difficulty in communication due to wearing masks, difficulty in purchasing parts for the maintenance, deterioration of skills due to reduced face to face class hours, and laxity in lifestyle were found. Conclusion: It was analyzed that the longer the corona pandemic, the lower the motivation of students due to uncertainty in the job market. [ABSTRACT FROM AUTHOR]

The human factors become the most important factor in aviation safety. In order to prevent accident, pilots should manage errors in the cockpit. International Civil Aviation Authority (ICAO) recommends airlines to implement line operation safety audit (LOSA) to identify the management of errors by pilots and understand real errors and the competencies. The LOSA may provide metrics of the prevalence of errors by each types and rate of trapping errors to management enhancing errors. Airlines may understand how crew respond and manage errors. The operator may enhance safety once they identify errors and train crew how they manage to reduce the most mismanagement errors. This study is to provide operators eight recommendations on how to enhance errors and LOSA understanding human errors collected through LOSA and enhancing the implementation of LOSA with guidance according to ICAO and Federal Aviation Administration. [ABSTRACT FROM AUTHOR]

Src family non-receptor tyrosine kinases are involved in signaling pathways which mediate cell growth, differentiation, transformation and tissue remodeling in various organs. In an effort to elucidate functional involvement of p60c-Src (c-Src) in spermatogenesis, the postnatal changes in c-src mRNA and c-Src protein together with kinase activity and subcellular localization were examined in mouse testes. c-src mRNA levels in testes increased during the first 2 weeks of postnatal development (PND). Following a decrease at puberty (PND 28), the c-src mRNA levels re-increased at adulthood (PND 50). Src kinase activity of testes was low at PND 7 but sharply increased prepubertally (PND 15) and highest at adulthood. Upon Western blotting, the level of c-Src protein was the highest in prepubertal testes but rather decreased in adult testes at PND 50. In adult testes, ubiquitination of c-Src proteins was apparent compared with immature one at PND 7, suggesting active turnover of c-Src by ubiquitination. In immature testes, c-Src immunoreactivity was largely found in the cytoplasm of the Sertoli cells. By contrast, in pubertal and adult testes intense immunoreactivity was localized at the adluminal and basal cytoplasm of Sertoli cells bearing elongated spermatids and early germ cells, respectively. The immunoreactivity of c-Src in the Leydig cells was increased during pubertal development, suggesting the functional involvement of c-Src in differentiated adult Leydig cells. Throughout postnatal development, some spermatogonia and spermatocytes showed intensive c-Src immunoreactivity compared with other germ cells, suggesting a possible role of c-Src in germ cell death. Taken together, it is suggested that c-Src may participate in the remodeling of the seminiferous epithelia and functional differentiation of Leydig cells during the postnatal development of mouse testes. [ABSTRACT FROM AUTHOR]