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A 66-year-old right-handed man developed pure anarthria following pure word deafness. In addition to language disorders, his behavior gradually changed and finally included violence against his wife. Brain magnetic resonance imagings revealed atrophy of the left perisylvian area, which included the inferior half of the precentral gyrus and the upper portion of the superior temporal gyrus, consistent with frontotemporal dementia (FTD). It has been documented as either a disorder of expressive language or as an impaired understanding of word meaning. Unlike with pure anarthria, pure word deafness is not included in the clinical diagnostic current criteria for FTD. However, a large variety of language symptoms can appear in FTD according to the distribution of pathological changes in the frontotemporal cortices. This case suggests that pure word deafness could be a prodomal symptom of FTD. [ABSTRACT FROM AUTHOR]

Presents a case report on pure amnesic syndrome with thymoma. Assessment on the cause and diagnosis of the condition; Details on the development of paraneoplastic limbic encephalitis which is characterized by amnesia; Results of routine laboratory tests including blood cell count, biochemistry and urinalysis.

A reply to the letter to the editor is presented concerning frontotemporal dementia.