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This article discusses the potential risk of acute kidney injury (AKI) and chronic kidney disease (CKD) in patients receiving BRAF/MEK inhibitor therapy for melanoma. Real-world data showed higher rates of AKI compared to clinical trials. The study found that patients who received BRAF/MEK inhibitors had a higher risk of CKD compared to a group of patients who underwent surgical resection alone. The study suggests that CKD is an important comorbidity in melanoma patients and further research is needed to understand the mechanisms and develop therapies to slow kidney function decline in these patients. [Extracted from the article]

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Rotational molding advantages include the production of a hollow part with no welding lines, either of small or big sizes, with no internal stresses and good surface details. However, the process is limited by the long cycle times, and its related high energy consumption. Different strategies can be followed to reduce such energy use. This work assesses the use of pressure inside the molds during the densification and cooling stages, finding reductions in overall cycle time of approximately 20%, because of the reduction in the heating time required but also to the increased cooling rate. The influence of such an approach on the production of composites with reed fibers has also been assessed, finding a similar trend towards cycle time reductions. The rotomolded samples' thermomechanical and rheological behavior were determined, finding that viscosity was not affected due to the incorporation of air during the moldings; besides, the homogeneity of the composites increased due to the mold pressurization. The parts obtained show good aesthetics and good thermomechanical behavior along the entire temperature range studied, and particularly for 10% composites; higher fiber ratios should be prepared via melt compounding. Therefore, the mold pressurization allows us to reduce both oven and cooling times, which can be translated into an increase in productivity and a decrease in energy consumption, which are undeniably related to the increase in the products' sustainability and cost. [ABSTRACT FROM AUTHOR]

Jonathan Shay argued that social, relational, and institutional contexts were central to understanding moral injury and conceptualised moral injury as a normative response to the betrayal of an individual's understanding of what is right by a more senior/authoritative "other". Using the conceptual lens of moral injury, this paper investigates academic staff experiences of HE during the COVID-19 pandemic and explores the rapid transition back to face-to-face teaching that took place in autumn 2020. To collect data, we used an online survey that opened in January 2021 and ran until the end of March 2021. A total of 663 complete questionnaires were received across the survey period. The questionnaire was comprised of ten topic-related questions, each of which included follow-up sub-questions and also invited participants to write in additional information. The majority of participants felt that during the course of the COVID-19 pandemic, they had acted in ways that put their own health and wellbeing at risk. Of those who had acted in ways that put their health and wellbeing at risk, they believed that their senior management were the most responsible for them acting in such ways, followed by the UK government. Qualitative data showed a systemic absence of leadership in the sector during the time, a sense of betrayal of staff and students by senior management and the government, and feelings of compulsion to act in ways which put lives at risk. On the basis of these results, we argue that there could be synergies between the situation facing healthcare staff and academics during the pandemic. Many of the experiences of HE academic staff during the pandemic reported to us in this research are resonant with the concepts of betrayal and moral injury and resulted in affective responses which we understand here in relation to feelings of guilt, shame, and anger, leading ultimately to poor mental health and wellbeing. This paper discusses implications for the HE sector going forward. [ABSTRACT FROM AUTHOR]

Adult de novo scoliosis is a chronic health condition characterised by a curvature in the ageing spine. It can cause debilitating back pain and significant visible differences. Yet there has been very limited research on the psychological effects of this condition, particularly around identity. Therefore, we undertook semi-structured interviews to explore the ways in which individuals with scoliosis understood their identity. Findings from narrative analysis highlight the ways in which individuals negotiate their identity in relation to their social roles, their ability to control their condition and things around them, the extent to which their condition is visible and the extent to which they experienced physical pain from their condition. This article concludes by highlighting the relationship between identity and scoliosis and offers practical implications and suggestions for future research. [ABSTRACT FROM AUTHOR]

In China, food waste at the consumption stage is at its highest when eating out. Therefore, this research aims to investigate the organisation of social, cultural, and material practices associated with eating-out in China, which result in food waste. By challenging the prevalent structure/agency dualism in traditional food waste studies, this research draws on Warde's conceptual framework of eating as a compound practice to offer a nuanced understanding of food waste. It provides a novel contribution to understanding how food waste might be reduced. A combination of semi-structured interviews and eat-along sessions were adopted in this study. 28 Chinese participants joined the research over a four-month period in 2017 in two Chinese cities. 26 in-depth semi-structured interviews were undertaken alongside 16 eat-along sessions. Qualitative data were interpreted using Thematic Analysis. The findings suggest that eating-out food practices can be understood through the following integrative practices: social organisation of meal occasions, judgement of aesthetic qualities, judgement of bodily capacity, and judgement of food functionality. Amongst these four practices, plate waste was attributed to the judgement of surplus foods' edibility and waste avoidance, which were explored through the three dimensions of eating-out food practice: temporality, materiality, and conventionality. [ABSTRACT FROM AUTHOR]

Polylactide (PLA) is one of the most commonly used biomaterials nowadays, with many recognized benefits, particularly in the packaging and single-use products industries. However, little research has been conducted on its stretching behavior. This work investigates the optimal conditions of biaxial stretching of injection-molded PLA samples produced under different processing conditions (pressure, drying, and pre-processing by extrusion, to simulate a recycling step). The injection-molded samples were characterized to determine their mechanical, thermal and thermo-mechanical behavior, water absorption, thermal behavior, and crystallization kinetics. The extruded samples showed reduced thermal stability, lower viscosity, decreased mechanical properties, and higher crystallization rates due to thermal degradation. However, the stretched samples provided similar properties regardless of the materials pre-processing. Regarding the assessment of the biaxial stretching process, processing at lower temperatures provides the films with a higher yield and breaking strength, while the time and strain rates have little influence on such properties. It was then determined that 82 °C is the optimal temperature for stretching the PLA samples. An increase in the stretch ratio provided a higher elastic modulus and higher values of opacity due to an increased crystallinity induced by stress during the process. Films as thin as 50 μm can be obtained by biaxially stretching injection-molded preforms, producing a deformation over 150% and acquiring good mechanical properties: about 90 MPa for the yield and a breaking strength and elastic modulus of 4000 MPa. [ABSTRACT FROM AUTHOR]

Background Poly (ADP-ribose) polymerase inhibitors (PARPi) have revolutionized the treatment of ovarian cancer; however, real-world data on kidney function among patients treated with PARPi are lacking. Methods We identified adults treated with olaparib or niraparib between 2015 and 2021 at a major cancer center in Boston, MA, USA. We determined the incidence of any acute kidney injury (AKI), defined as at least a 1.5-fold rise in serum creatinine from baseline in the first 12 months following PARPi initiation. We calculated the percentage of patients with any AKI and sustained AKI and adjudicated the etiologies by manual chart review. We compared trajectories in estimated glomerular filtration rate (eGFR) among PARPi-treated and carboplatin and paclitaxel-treated patients with ovarian cancer, matched by baseline eGFR. Results Of 269 patients, 60 (22.3%) developed AKI, including 43 of 194 (22.1%) olaparib-treated patients and 17 of 75 (22.7%) niraparib-treated patients. Only 9 of 269 (3.3%) had AKI attributable to the PARPi. Of the 60 patients with AKI, 21 (35%) had sustained AKI, of whom 6 had AKI attributable to the PARPi (2.2% of the whole cohort). eGFR declined within 30 days post-PARPi initiation by 9.61 (SD = 11.017)  mL/min per 1.73 m2 but recovered by 8.39 (SD = 14.05)  mL/min per 1.73 m2 within 90 days after therapy cessation. There was no difference in eGFR at 12 months post-therapy initiation in patients receiving PARPi or controls receiving carboplatin and paclitaxel (P  = .29). Conclusions AKI is common following PARPi initiation as is a transient decline in eGFR; however, sustained AKI directly attributable to the PARPi and long-term eGFR decline are uncommon. [ABSTRACT FROM AUTHOR]

Background Clinical trials of immune checkpoint inhibitors (ICIs) often do not include patients with advanced chronic kidney disease (CKD). We aimed to determine the safety of ICIs in patients with cancer and advanced CKD (stages 4-5 CKD, estimated glomerular filtration rate [eGFR] <30 mL/minute/1.73 m2). Patients and Methods Patients with advanced CKD from the Mass General Brigham network who received ICIs (n = 91) were compared against those receiving nephrotoxic (n = 113) and non-nephrotoxic (n = 130) antineoplastic therapies, respectively. Rates of new-onset kidney failure (end-stage kidney disease or sustained eGFR ≤10 mL/minute/1.73 m2) and AKI were compared. Among ICI-treated patients, we modeled Fine-Gray subdistribution hazards to compare immune-related adverse event (irAE) risk and used Kaplan-Meier analysis to compare overall survival in patients with advanced CKD to those with eGFR ≥30 mL/minute/1.73 m2. Results Rates of new-onset kidney failure were similar at 1 year following initiation of ICIs (10.0%), nephrotoxic (6.2%), and non-nephrotoxic antineoplastic therapies (9.3%) (P =.28). AKI rates were also similar: 17.5%, 17.6%, and 20% of patients in each cohort, respectively (P =.87). Advanced CKD did not increase the risk of developing irAEs (adjusted hazard ratio [HR] 1.28, 95% CI, 0.91-1.81). However, patients with advanced CKD who received ICIs had a decreased overall survival compared with patients with eGFR ≥30 mL/minute/1.73 m2 (HR 1.30 for death, 95% CI, 1.02-1.66, P =.03). Conclusion ICIs are not associated with increased risk of AKI or new-onset kidney failure compared with other antineoplastic therapies in patients with advanced CKD. Advanced CKD did not increase the risk of extra-renal irAEs, although these patients suffered from lower overall survival. [ABSTRACT FROM AUTHOR]

Onconephrology, the field that focuses on the intersection of cancer and kidney disease, is facing several challenges. One major challenge is the decline in the nephrology workforce, which leads to long wait times for appointments and suboptimal management of kidney disease. Another challenge is the limited research resources in onconephrology, which hinders the advancement of knowledge in this area. Fragmented clinical guidelines and a lack of structured continued medical education are also obstacles in providing optimal care. To address these challenges, proposed solutions include educating providers and patients, creating multidisciplinary cancer care teams, increasing research partnerships, developing new diagnostic tools, and expanding onconephrology training programs. [Extracted from the article]

Objective: Research on 'moral injury'—the psychological wound experienced by military personnel and other 'functionaries' whose moral values are violated—has proliferated in recent years. Many psychological researchers, including those in the UK, have subscribed to an increasingly individualised operationalisation of moral injury, with medicalised criteria that closely mirrors PTSD. This trend carries assumptions that have not been comprehensively verified by empirical research. This study aims to explore UK military veterans' experiences of, and challenges to, their moral values in relation to their deployment experiences, without prematurely foreclosing exploration of wider systemic influences. Method: Twelve UK military veterans who served in Afghanistan and/or Iraq were interviewed, and the data were analysed thematically and reflexively. Results: Three inter‐related themes were generated: (1) 'you've been undermined', (2) 'how am I involved in this?' and (3) 'civilianised'. Conclusions: The analysis suggests that several assumptions privileged in moral injury research may be empirically contradicted, at least in relation to the experiences of UK military veterans. These assumptions include that moral injury is exclusively driven by individual, episodic acts of commission and omission, invariably leads to guilt and necessarily bifurcates into variants of either perpetration or betrayal. Instead, participants understood the moral violations they experienced as socially contingent. Rather than 'treating' moral injury as a disorder of thinking and feeling located within an individual, the socially contextualised understanding of moral injury indicated by this study's findings may prompt the development of psychological and social interventions that understand moral injury as the fallout of what occurs between people and within systems. [ABSTRACT FROM AUTHOR]

Moral injury was originally conceived as a socially‐inflicted wound of betrayal experienced by military veterans (Shay, 1994). However, moral injury has since been redefined by psychological researchers as an individualised, predominantly perpetration‐driven, and psychopathological phenomenon (e.g., Currier et al., 2015; Jinkerson, 2016). However, social scientific researchers (e.g., Hodgson & Carey, 2017; Molendijk, 2019; Wiinikka‐Lydon, 2017) have contested mainstream psychology's medicalisation and decontextualisation of moral injury. This theoretical review integrates insights from across these discourses, and brings them into dialogue with ideas from moral psychology, evolutionary science, and community psychology. The aim of this cross‐disciplinary review is to promote a more holistic understanding of moral injury that does justice to its individual and social dimensions. Drawing on these different theoretical strands, this paper proposes that moral injury can be best understood as a psychological wound to basic human needs for social belonging and cohesion. The implications of this integrative understanding of moral injury for applied psychologists and other societal actors are explored. While the relevance of moral injury to civilian populations such as health and social care professionals is clear (e.g., Dombo et al., 2013; French et al., 2021), this paper focuses on military veterans, whose experiences originally prompted the coinage of the term. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement. [ABSTRACT FROM AUTHOR]

Employers are increasingly selecting and developing employees based on skills rather than qualifications. Governments now have a growing focus on skilling, reskilling and upskilling the workforce through skills-based development rather than qualifications as a way of improving productivity. Both these changes are leading to a much stronger interest in digital badging and micro-credentialing that enables a more granular, skills-based development of learner-earners. This paper explores the use of an online skills profiling tool that can be used by designers, educators, researchers, employers and governments to understand how badges and micro-credentials can be incorporated within existing qualifications and how skills developed within learning can be compared and aligned to those sought in job roles. This work, and lessons learnt from the case study examples of computing-related degree programmes in the UK, also highlights exciting opportunities for educational providers to develop and accommodate personalised learning into existing formal education structures across a range of settings and contexts. [ABSTRACT FROM AUTHOR]

The paper explores how second-generation Turkish-German 'returnees' benefit from their "inbetweenness" in their ancestral homeland and initiate a process of re-inventing themselves as 'transcultural mediators'. A thematic-narrative analysis was undertaken on 43 in-depth interviews with second-generation Turkish-German 'return' migrants to Antalya who had acquired jobs in the tourism sector. The paper unpacks how this tourism hub provides "third spaces" distanced from prominent national and diasporic identities, and the ways in which these liberating spaces encourage the lifestyle-oriented, cosmopolitan second-generation 'returnees' to re-position themselves in their translocal social fields. The findings illustrate how the second generation, who formerly endured "being twice a stranger" in Germany and Turkey, undertake a process of transculturation in Antalya, and utilize their "transcultural capital" (i.e. bilingual skills, bi- multilingualism, translocal habitus) to perform different aspects of their multiple and hybrid identities, gain economic independence and build social relations. [ABSTRACT FROM AUTHOR]

The Rich Kids of Instagram (RKOI) portray luxury lifestyles on social media. The potential roles of travel and transport within these online displays of affluence have not yet been examined. This paper's purpose is to analyse how transport modes and luxury travel are depicted and interrelated through RKOI images. Co-occurrence analyses were conducted using a data set of Instagram posts with RKOI as a hashtag (2012–2018) to visualize the roles of transport modes and luxury travel in RKOI image construction. The findings demonstrate that both energy-intensive transport modes and luxury travel, whether through air/watercraft or luxury cars, play a vital role in signaling RKOI's self-image on Instagram, with gendered differences. The article contributes an original conceptual model of how RKOI construct their image using transport modes and luxury travel. Implications for the social normalization of carbon-intensive transport choices, coupled with luxury destinations as a backdrop, are discussed. [ABSTRACT FROM AUTHOR]

2 aImmunosuppressant therapy used in molnupiravir-treated patients were prednisone and mycophenolate; nirmaltrelvir/ritonavir-treated patients were on daratumumab and dexamethasone. In our healthcare system, we found that oral antiviral use was uncommon in patients with advanced CKD and kidney failure; we identified only 27 treated patients in the first 10 months since EUA. Drug-drug interactions were common in patients treated with nirmatrelvir/ritonavir; seven patients (58.3%) required an adjustment to one or more medications due to the FDA-reported significant drug interactions (Table 1 footnote). [Extracted from the article]

Aviation remains a problematic sector of the global economy in times of climate emergency. Grounded in the ideology of reconfiguration, we adopt a system transitions perspective to address high emissions leisure travel. Our focus falls on the marketing communications of airlines as a critical component in the prevailing sociotechnical regime. Thematic analysis of the e-mail marketing communications of selected airlines revealed three prominent tropes: adventure and discovery; privilege ; and urgency. These communications bring air travel into the everyday lives of consumers and accelerate the turnover time of tourist consumption. Time is mobilized to create a sense of resource scarcity and urgency to consume, paradoxically in a situation characterized by oversupply. The COVID-19 pandemic has presented a unique opportunity for structural reform of the airline industry. Component substitution to address airline marketing is required as an important step toward overcoming consumer moral disengagement and reconfiguring the airline industry. [ABSTRACT FROM AUTHOR]

In 2019–2020, 80,000 children in England were looked after by the state or adopted. Whilst extensive research has explored the experiences and outcomes of children in the care system, much less research has focused on the experiences of their parents. This paper uses the Power Threat Meaning Framework to provide a qualitative synthesis of literature exploring the experiences of birth parents in England who have had a child removed from their care by the state in order to understand how early interpersonal adversity interacts with social disadvantage to bring these families to the attention of child protection services. This paper aims to problematise the individualistic discourse blaming parents who cannot look after their children and offer an alternative perspective by examining the impact of developmental trauma and systemic adversity on birth parents prior to, during and following care proceedings. This paper argues that significant policy changes are needed to support vulnerable families, with an emphasis on trauma‐informed care and tackling levels of deprivation. This approach challenges psychology and psychiatry (Psy) professionals to use their privileged position to call for broader societal change to address the root causes of distress within this group. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement. [ABSTRACT FROM AUTHOR]

We conducted a systematic review to answer the following: (a) Is there any evidence to support increased prevalence of suicidality and self-harm (i.e. self-harm or suicidality) in urban versus rural environments? (b) What aspects of the urban environment pose risk for suicidality and self-harm? Thirty-five studies met our criteria. Our findings reflect a mixed picture, but with a tendency for urban living to be associated with an increased risk of suicidality and self-harm over rural living, particularly for those living in deprived areas. Further research should focus on the clustering and additive effects of risk and protective factors for suicidality and self-harm in urban environments. [ABSTRACT FROM AUTHOR]

This paper presents work from an ongoing study into the use of post-consumer waste polymer in the rotational moulding process. Raw plastic recyclate, predominantly consisting of polyethylene, was processed into polymer powders containing an additive package suitable for rotational moulding, with and without the addition of a compatibiliser. Rheological studies on the materials showed very high viscosities at low shear rates in comparison with materials typically used in rotational moulding, which has significant implications for melt flow and bubble removal during the process. It was possible to mould the materials successfully, but poor surface finishes were achieved. Impact strength was drastically lower for recyclate mouldings compared with virgin material. Tensile strength of the recyclate mouldings was reduced compared to virgin polyethylene, but results indicated that optimising the processing conditions could lead to improvements. This work gives some baseline indicators to inform further planned work on optimising processing conditions and identifying viable material compositions. [ABSTRACT FROM AUTHOR]

Measured by psychologists, conceived in critical terms, popularised as satire, and exploited by politicians, meritocracy is a dilemmatic concept that has changed its meanings throughout history. Social psychologists have conceptualised and operationalised meritocracy both as an ideology that justifies inequality and as a justice principle based on equity. These two conceptualisations express opposing ideas about the merit of meritocracy and are both freighted ideologically. We document how this dilemma of meritocracy's merit developed from meritocracy's inception as a critical concept among UK sociologists in the 1950s to its operationalisation by U.S. and Canadian social psychologists at the end of the 20th century. We highlight the ways in which meritocracy was originally utilised, in part, to critique the measurement of merit via IQ tests, but ironically became a construct that, through its psychologisation, also required measurement. Through the operationalisation of meritocracy, social psychologists obscured the possibility of critiquing meritocracy and missed the opportunity to offer alternatives to a system that has been legitimised by their own work. A social psychology of meritocracy should take into consideration the ideological debate around its meaning and value and the implications of its measurement and study. [ABSTRACT FROM AUTHOR]

Accessible summary: What is known on the subject?: Dementia affects an increasing number of people and a person with dementia requires significant levels of care.Dementia care is often delivered by family members.Caring for someone with dementia places significant demand on the carer and support for the carer is often needed. What the paper adds to existing knowledge?: Research has been conducted into caregivers' experiences of caring for someone with dementia, but a synthesis of findings for studies from the UK is needed to collate the research evidence and provide an account of the common trends within the existing research.This paper adds to existing knowledge by highlighting the key difficulties experienced by carers of a person with dementia in their caring role and their experiences with support services across the existing research evidence. What are the implications for practice?: Improvements to the process of dementia assessment and the process of receiving a dementia diagnosis are needed.Information and support needs to be more accessible for the carer of a person with dementiaCultural differences need to be acknowledged in the support and information offered to carers of a person with dementia. Aim: To understand the experiences of informal carers' of individuals with dementia in the UK when engaging with services for support in their caring role. Methods: Following the PRISMA guidelines, a qualitative systematic literature review was carried out. Six Internet databases were searched. Results were screened, and eligible studies were appraised using Critical Appraisal Skills Programme (CASP, 2019) and data synthesized using Evan & Pearson (2001) and Evans (2002). Results: The search returned 231 records, 11 were selected for critical appraisal and data synthesis. Four main themes (information for carers, process of diagnosing dementia, difficulties accessing support and cultural differences of experiences of services) were extracted. Discussion: Carers experience services as providing inadequate support for the Person with Dementia (PwD) and themselves for support relating to dementia. Difficulties in receiving information and support were experienced from before diagnosis to end‐of‐life (EoL) care. Additionally, cultural differences were found in carers' experiences. Implications for practice: The provision of and access to dementia support should be improved; more information for carers about dementia and dementia services is needed; cultural differences need to be appreciated in the support and information offered. [ABSTRACT FROM AUTHOR]

Allergy, anaphylaxis, anxiety, cognitive behavioural therapy, emotions, group, intervention, online, parent, support A brief psychological intervention for mothers of children with food allergy can change risk perception and reduce anxiety: outcomes of a randomized controlled trial. A previous trial of a brief CBT intervention for FA parents4 reported an effect size of I d i = .50 on anxiety, which was converted to I f i = 0.25 for use in this power calculation. [Extracted from the article]

Theoretical approaches have tended to understand perinatal distress through either individual or socio-cultural factors. In contrast, Natasha Mauthner proposed a relational model that understands perinatal distress in the context of interpersonal relationships. This study aims to build on Mauthner's work to explore how women speak about their relationships in connection to their stories of perinatal distress and recovery. Eight women were interviewed for the study. All women had at least one child under the age of three and self-identified as having experienced distress in the perinatal period. Interviews were recorded, transcribed and analyzed using Voice Centred Relational Analysis. Four broad themes were identified: (i) the role of practical support, (ii) the role of emotional support, (iii) relational dynamics, and (iv) the role of socio-cultural norms. Whilst some women experienced practical and emotional support in their relationships, those who did not linked a lack of support to their feelings of distress. Relationships were also found to reinforce unhelpful social norms around motherhood and mental health, as well as offering a space to resist norms and create wider discourses about what it means to be a mother. This study suggests that organizations supporting women in the perinatal period should focus on women's relational needs and consider the cultural discourses of motherhood that they perpetuate. [ABSTRACT FROM AUTHOR]

In this paper, we present results from an extensive survey of United Kingdom (UK) university academics investigating satisfaction with senior managers and university governance: the Senior Management Survey (SMS). In total, 5888 academic staff across the United Kingdom Higher Education (HE) sector completed the survey, and results were used to construct a league table of staff satisfaction with management. This table is a stark indictment of the current state of the UK HE sector, showing a mean satisfaction score of 10.54%. The SMS also collected qualitative data, and we extend the league table's insights using these data. Thematic analysis revealed seven major themes: the dominance and brutality of metrics; excessive workload; governance and accountability; perpetual change; vanity projects; the silenced academic; work and mental health. We conclude with a discussion of how this statactivist research can be used to bring about change in management and governance of UK HE. [ABSTRACT FROM AUTHOR]

Purpose: This paper aims to explore the implications of integrating humanoid service robots into hospitality service encounters by evaluating two service prototypes using Softbank Robotics' popular service robot Pepper™: to provide information (akin to a receptionist) and to facilitate order-taking (akin to a server). Drawing both studies together, the paper puts forward novel, theory-informed yet context-rooted design principles for humanoid robot adoption in hospitality service encounters. Design/methodology/approach: Adopting a multiple method qualitative approach, two service prototypes are evaluated with hospitality and tourism experts (N = 30, Prototype 1) and frontline hospitality employees (N = 18, Prototype 2) using participant observation, in situ feedback, semi-structured interviews and photo-elicitation. Findings: The adoption of humanoid service robots in hospitality is influenced by the following four layers of determinants: contextual, social, interactional and psychological factors, as well as extrinsic and intrinsic drivers of adoption. These empirical findings both confirm and extend previous conceptualizations of human-robot interaction (HRI) in hospitality service. Research limitations/implications: Despite using photo-elicitation to evoke insight regarding the use of different types of service robots in hospitality, the paper mostly focuses on anthropomorphized service robots such as Pepper™. Practical implications: Adopting humanoid service robots will transform hospitality operations, whereby the most routine, unpleasant tasks such as taking repeat orders or dealing with complaints may be delegated to service robots or human-robot teams. Social implications: Working with and receiving service from Pepper™ changes the service encounter from direct practical, technical considerations to more nuanced social and psychological implications, particularly around feelings of self-esteem, social pressure and social judgment. Originality/value: This paper presents one of the first empirical studies on HRI in hospitality service encounters using Softbank Robotics' Pepper™. In doing so, the paper presents a novel framework for service robot adoption rooted in first-hand user interaction as opposed to previous, theory-driven conceptualizations of behavior or empirical studies exploring behavioral intention. [ABSTRACT FROM AUTHOR]

Therapeutic relationships within psychiatric settings are highlighted as important throughout the literature. However, research from the forensic inpatient perspective is limited. We address this gap by exploring the patient-staff relationships within forensic mental health inpatient services, from the patient's perspective. Thirty adult male forensic inpatients were interviewed about their experiences on the ward and their interactions with staff. Our analysis examines inpatients experiences of respectful and reciprocal relationships, relationships that empower, a disinterest in their patients' and authoritarian relationships. This study concludes by highlighting the need to prioritise the development of reciprocal relationships within forensic services. [ABSTRACT FROM AUTHOR]

Difficulties associated with Autism Spectrum Disorders can cause considerable impact on personal, familial, social, educational and occupational functioning. Living with a child who has an Autism Spectrum Disorder can therefore pose a challenge to family members, including typically developing siblings. However, it is only in recent years that the experience of typically developing siblings has become a focal point. A systematic review using keywords across six databases was undertaken to summarise qualitative studies that focused on the experience of being a sibling of a child with an Autism Spectrum Disorder. Fifteen studies met inclusion criteria and a thematic synthesis was completed. The synthesis found that having a sibling who has an Autism Spectrum Disorder can impact typically developing sibling's self-identity and personal development in a number of ways. Similarly, interactions with the sibling who has Autism Spectrum Disorders and with other individuals can evoke a myriad of experiences that can both benefit and challenge typically developing siblings. The ability of typically developing siblings to cope with adverse experiences needs to remain a focus. This synthesis concludes that further research is needed to identify which methods are the most effective in supporting typically developing siblings of children with Autism Spectrum Disorders. [ABSTRACT FROM AUTHOR]

Aiming to further plastics recycling via rotational moulding plastics processing, blends of virgin and recycled polyethylene sourced from post-consumer plastics were developed. Three different kinds of recycled high density polyethylene – from bottles, pipes and mixed household waste – were compounded with virgin medium density polyethylene in an extruder. The ideal amount of recyclate was chosen based upon the impact resistance of different contents (25, 50 and 75%) of recycled plastic with the 50/50 blend found to have the best performance. Compression-moulded and rotationally-moulded samples were analysed through falling dart impact test, flexural test, melt flow rate and differential scanning calorimetry analysis. The impact results of the compression-moulded samples showed an increase in the impact resistance of the blends with a higher melt flow index and lower degree of crystallinity. The rotationally-moulded specimens displayed much lower impact resistance than the pure virgin plastic and a 20–30% reduction in the flexural moduli, which were ascribed to the crystalline structure of the part and issues in the blends' rotomoulding process. It was concluded that blending virgin and recycled polyethylene for rotational moulding can be an effective way to further plastics recycling inside the Circular Economy context. [ABSTRACT FROM AUTHOR]

Generating negative news coverage of state welfare provision has been identified as a strategy designed to create public support for radical policies aimed to reduce such provision. To date, research of this kind has focused on scandals and crises. However, little is known about the complex relationship between media representations of specific events, and those of media representations in the lead up to these events, what we refer to as periphery representations. Employing a content and frame analysis, this paper analyses the frequency and intensity of peripheral representations of the National Health Service (NHS) in the British print media for 1 week a month before and for 1 week during three key events in recent NHS history: the official consultation period for the Health and Social Care Act; the publication of Five-Year Forward View, and the first Junior Doctor Strike. This article finds that negative NHS representations in articles that are peripheral to particular topical issues of controversy evidence fluctuations, amplifications and intensities across time periods, depending on the particular context. The paper concludes by arguing that repetition of negative themes in news helps to build a sensibility of 'inadequacy' of vital services. We hope that this focus on the ways in which amplifications and de-amplifications in negative intensity of peripheral NHS representations across time and content, helps to contribute to debate about the complex interplay between public health services, media representation and policy consent. [ABSTRACT FROM AUTHOR]

Despite increasing geographic mobility among academic staff, gendered patterns of involvement in academic mobility have largely escaped scrutiny. Positioned within literatures on internationalization, physical proximity, gender and parenthood in academic mobility and understandings of gender as a process enacted through both discursive and embodied practices, we use discourse analysis based on interviews with academics in New Zealand to examine differences in language that create differing realities with regards to gender and obligations of care in academic mobility decisions. The findings reveal how academic mobility is discursively formulated as 'essential' to successful academic careers, with the need for frequent travel justified despite advances in virtual communication technologies. Heteronormative discourses are shown to disrupt and fragment the opportunities female academics have to engage in academic mobility. However, we also uncover ways in which these discourses are resisted, wherein fathers articulate emotional strain associated with academic mobility. The article shows how discourse works to constitute the essentialization of academic mobility, and the uneven gendered practices associated with it, whilst also giving voice to gender inequities in academic mobility from the southern hemisphere. [ABSTRACT FROM AUTHOR]

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This article draws on the conflicting arguments surrounding outdoor adventure tourism activities to determine if such activities might usefully be considered beneficial for humans and nature, and how they might offer avenues for sustainable tourism practice. Research in the field has often examined outdoor adventure activities through a lens that either highlights their negative environmental impacts or has sought to conceptualise motivations and/or experiences. In this article, we argue that through practices that are often seen as destructive, there is the possibility to think differently about human-nature relationships and pro-environmentalism. To explore these issues, we draw on data collected from a series of semi-structured interviews with outdoor adventure tourists. Our analysis highlights how outdoor adventure tourism facilitates reconnections to nature, offering potential wellbeing impacts and pro-environmental attitudes and behaviours. We conclude that outdoor adventure activities as a form of sustainable tourism have potential implications for our understanding of, and engagement with, sustainability, mental health and wellbeing. [ABSTRACT FROM AUTHOR]

This paper focuses on establishing a conceptual grounding for the value of dignity in tourism employment for achieving decent work as part of the sustainable development agenda. Dignity is widely acknowledged as a key driver for 'good' work, but little conceptual grounding on the value of dignity in tourism employment has been established. This paper will contribute to the theoretical debate on sustainable tourism by providing a critical review of frameworks for decent work, workplace dignity (or its absence), and understandings of identity. We will explore how the context and conditions of tourism employment are conducive (or not) for offering dignified and sustainable employment. This paper makes two original contributions to knowledge. First, it introduces a psychosocial understanding of dignity in tourism employment, reflecting its deeply rooted individual, organisational, societal and policy aspects, and recognising the actors involved. Second, the critical importance of dignity in tourism employment for achieving the Sustainable Development Goals (SDGs) is discussed, with future research directions identified. [ABSTRACT FROM AUTHOR]

Holidaying is an important leisure pursuit and, for a growing minority, air travel is the default mode for holiday mobility. However, the current trend of increasing demand for air travel runs contrary to climate-related sustainability goals. Efforts to motivate reductions in consumption of holiday air travel must contend with the embeddedness of flying as a social practice and should be informed by an understanding of how people prioritize air travel for holidays relative to other forms of consumption. Using data drawn from a survey of 2066 British adults, this exploratory study uses a novel method to assess the willingness of individuals to sacrifice holiday air travel relative to their willingness to make changes to their daily consumption patterns. We find a greater readiness to undertake additional expense (of time, effort, or money) than to retrench incumbent consumption patterns in order to fly for holidays. Reluctance to sacrifice for the sake of flying was greatest with regards to those items that are most associated with the basic infrastructure of modern life (e.g. mobile phones). Examining product-specific pro-environmental sacrifice in relative terms, our findings suggest that voluntary reductions in flying are more plausible than other modes of pro-environmental sacrifice. [ABSTRACT FROM AUTHOR]

This paper provides an empirical application of some recent developments in the social science of sustainability to understanding sustainable transport behaviour. We analyse talk about holidaymaking taken from interviews with self-defined "eco" or "sustainable" tourists. The focus of this paper explores the ways in which participants understand and reconcile the potential conflict of air transport and the notion of sustainable holidays. We identify a number of discursive strategies participants used to project and maintain positive self-representations in the context of complex, often incompatible constructions of sustainability derived from this particular dilemma. Such strategies are considered as concrete examples of the psychosocial organisation of denial and thus offer discursive barriers to sustainable transport futures. However, the analysis also demonstrates the ways in which some individuals were able to resist or challenge such forms of socially organised denial. The potential implications of these discursive barriers and strategies for sustainable transport futures and the tourism sector are discussed. [ABSTRACT FROM AUTHOR]

Gastrointestinal stromal tumors are uncommon when compared to all gastrointestinal neoplasms but are the most common mesenchymal tumors of the gastrointestinal tract. The largest gastrointestinal stromal tumor ever recorded in literature weighed approximately 6.1 kg and measured 39 cm × 27 cm × 14 cm. About two-thirds of GISTs are malignant. The tumor size, mitotic rate, cellularity, and nuclear pleomorphism are the most important parameters when considering prognosis and recurrence. The definitive treatment for these tumors is resection. In the year 2000, the first patient was treated with the tyrosine kinase inhibitor imatinib and since then, gastrointestinal stromal tumors with high-risk features have been treated successfully with tyrosine kinase inhibitors. We present the largest gastrointestinal stromal tumor recorded in medical literature measuring 42.0 cm × 31.0 cm × 23.0 cm in maximum dimensions and weighing in at approximately 18.5 kg in a 65-year-old African-American male who presented with increased abdominal distention. The mass was successfully excised, and the patient was treated with imatinib without local or distant recurrence 1.5 years postoperatively. [ABSTRACT FROM AUTHOR]

Debates surrounding the human impact on climate change have, in recent years, proliferated in political, academic, and public rhetoric. Such debates have also played out in the context of tourism research (e.g. extent to which anthropogenic climate change exists; public understanding in relation to climate change and tourism). Taking these debates as its point of departure, whilst also adopting a post-structuralist position, this paper offers a Foucauldian Discourse Analysis of comments to an online BBC news article concerning climate change. Our analysis finds three key ways responsibility is mitigated through climate change talk: scepticism towards the scientific evidence surrounding climate change; placing responsibility on the “distant other” through a nationalistic discourse; and presenting CO2as “plant food”. The implications of these ways of thinking about climate change are discussed with a focus on how this translates into action related to the sustainability of tourism behaviours. In doing so, it concludes that a deeper understanding of everyday climate talk is essential if the tourism sector is to move towards more sustainable forms of consumption. [ABSTRACT FROM AUTHOR]

The poem "SWEET DUMPLING (FRIED IN OIL)" by Paul Hanna is presented. First Line: looming over the island I have just uncovered; Last Line: palpitating and I am sorry.

The poem "SHARUUNAQIA" by Paul Hanna is presented. First Line: we cannot understand what you are saying; Last Line: will be of befuddlement and regret.

Relapsed ANCA associated vasculitis following Oxford AstraZeneca ChAdOx1-S COVID-19 vaccination: A case series of two patients The coronavirus disease 2019 (COVID-19) pandemic has precipitated the largest vaccination initiative in history.1 With a programme of this scale comes increasing descriptions of rare glomerular conditions developing post vaccination.2 We report two patients with relapsed microscopic polyangiitis (MPA) ANCA associated vasculitis (AAV) who received the Oxford AstraZeneca ChAdOx1-S vaccine (AZV) within 5 weeks of developing symptoms (see Table 1). Whilst single cases of de novo AAV have been described following each of the AZV, Moderna and Pfizer COVID-19 vaccinations,2-5 this is the first report of AAV relapse following COVID-19 vaccination. [Extracted from the article]