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The availability of the intraoperative MRI and real-time neuronavigation has dramatically changed the principles of surgery for gliomas. Current intraoperative computer-aided technologies permit perfect localization of the neoplasm, precise estimation of its volume, and clear definition of its interrelationships with the eloquent brain structures. This allows maximal tumor resection with minimal risk of postoperative disabilities. Under such conditions the medical treatment has become significantly dependent on the quality of the provided information and can be designated as information-guided management. Therefore, appropriate management of the wide spectrum of the intraoperative medical data and its adequate distribution between members of the surgical team for facilitation of the clinical decision-making is very important for attainment of the best possible outcome. Further progress in advanced neurovisualization, robotics, and comprehensive medical information technology has a great potential to increase the safety of the neurosurgical procedures for parenchymal brain tumors in the eloquent brain areas. [ABSTRACT FROM AUTHOR]

Abstract  Rapid, efficient, and reproducible procedures for isolating DNA before PCR gene amplification are essential for the diagnosis of piroplasms. In this study, we evaluated the ease and reliability of detecting Theileria equi by PCR using pre-extracted DNA samples (by QIAamp DNA Mini Kit and phenol-chloroform methods) compared with blood spotted on FTA cards as PCR templates. Although minimal variations in limit of detection were observed among the methods compared, overall, the use of pre-extracted DNA samples and blood spotted on FTA cards had comparable detection limits. These results indicate that T. equi infection can be efficiently detected directly from FTA cards by PCR without the need for pre-extraction of DNA from blood samples. [ABSTRACT FROM AUTHOR]

Background: Stereotactic Gamma Knife is one of the leading methods used for the stereotactic radiosurgical treatment of intracranial leasions. Stereotactic irradiation allows a very precise delivery of high-dose radiation into the target volume while sparing surrounding normal tissue. In addition, Gamma Knife Perfexion can create complex shapes irradiation field using secter. Therefore, quality control of the machine is increasingly more important. To date, the study on irradiation accuracy has been done using a variety of methods. Although the film, the dosimeter, and the gel phantom is a tool which is used as a method of quality control, advantages and disadvantages exist for each. We focused on the flat panel detector Therefore, we examined the quality control of gamma knife using a flat panel detector. In this study, we compared the quality control study using a variety of methods and quality control study using Flat panel detector. Methods: The Flat Panel Detector was positioned parallel to the front of collimator helmet of Gamma Knife and was irradiated by gamma ray for a few minutes while moving it axially at intervals of 2mm. Comparing the results obtained in the quality control method of the image analysis results and other. Result: Each source of 192 cobalt-60 gamma ray was clearly confirmed on image. Using the images obtained by this method enabled us to visually evaluate irradiation by Gamma Knife. Although similar results can be obtained in other ways, this approach results were obtained more easily in real time. Conclusion: In this study, using a Flat Panel detector was able to find it easy to check the gamma-ray irradiation of each Sector. Further, by combining this method and other methods, it can be more easily quality control has been suggested Disclosure: No significant relationships. [ABSTRACT FROM AUTHOR]