92 results on '"Grimsgaard AS"'
Search Results
2. Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries.
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Reinikainen, Jaakko, Kuulasmaa, Kari, Oskarsson, Viktor, Amouyel, Philippe, Biasch, Katia, Brenner, Hermann, Ponti, Roberto De, Donfrancesco, Chiara, Drygas, Wojciech, Ferrieres, Jean, Grassi, Guido, Grimsgaard, Sameline, Iacoviello, Licia, Jousilahti, Pekka, Kårhus, Line L, Kee, Frank, Linneberg, Allan, Luksiene, Dalia, Mariño, Joany, and Moitry, Marie
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- 2024
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3. Lifestyle factors as mediators of area-level socioeconomic differentials in mental health and cognitive function: the Tromsø Study.
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Tiwari, Sweta, Cerin, Ester, Wilsgaard, Tom, Løvsletten, Ola, Grimsgaard, Sameline, Hopstock, Laila Arnesdatter, Schirmer, Henrik, Rosengren, Annika, Kristoffersen, Kathrine, and Løchen, Maja-Lisa
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LIFESTYLES ,CROSS-sectional method ,MENTAL health ,COGNITION ,SOCIOECONOMIC status ,PHYSICAL activity ,SOCIAL classes ,FACTOR analysis ,DESCRIPTIVE statistics ,RESEARCH funding ,SMOKING - Published
- 2024
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4. What counts? A Delphi consensus-based approach to interpreting accreditation standards for Direct Client Activities in clinical psychology and clinical neuropsychology programs.
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Anderson, Rebecca A., Gooi, Chien Hoong, Oxenham, Vincent, Player, Michelle, Grimsgaard, Cathrine, Collison, James, Kambouropoulos, Alexa, and Moses, Karen
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CONSENSUS (Social sciences) ,COGNITION disorders ,NEUROPSYCHOLOGY ,ACCREDITATION ,HOSPITAL medical staff ,CLINICAL psychology ,BENCHMARKING (Management) ,CLINICAL competence ,ANXIETY ,SUPERVISION of employees ,DELPHI method - Abstract
Despite operating from the same professional accreditation standards, discrepancies in what is recorded as Direct Client Activities (DCA) in postgraduate psychology trainee logbooks have been noted across training programs in Australia. The aim of this study was to create a consensus-based list of DCA to guide the completion of trainee logbooks while undertaking practicums in clinical psychology or clinical neuropsychology. A modified Delphi approach was used to gather data across three rounds. Two expert panels, representing the two areas of practice endorsement (AoPEs), rated the degree to which they agreed or disagreed with a range of activities being recorded as DCA in trainee logbooks. Activities with over 80% agreement or disagreement during any round were accepted or rejected from the final list, respectively. Sixteen activities for clinical psychology and 30 activities for clinical neuropsychology were endorsed by the expert panels. Only nine activities across the two panels did not reach consensus over the three rounds. This study has created a list of consensus activities within these two AoPEs which will facilitate benchmarking activities, and reduce confusion and anxiety for trainees, supervisors, and placement coordinators. Discrepancies do, however, remain across the AoPEs, warranting further clarification and definition refinement. What is already known about this topic: Logbooks are a key strategy in ensuring individual trainees and postgraduate training programs are meeting minimum standards set by accrediting bodies. Although required by the Australian Psychology Accreditation Council (APAC) to be recorded in trainee logbooks, there is a lack of consensus across Australian postgraduate psychology program providers as to what constitutes "Direct Client Activities". Inconsistent logging practices prevents benchmarking and creates confusion and anxiety for trainees, supervisors, and placement coordinators. What this topic adds: This paper was the first, to our knowledge, to obtain expert consensus on trainee Direct Client Activities for logbook recording within the clinical psychology and clinical neuropsychology areas of practice endorsement. The list provides greater certainty for "what counts" as Direct Client Activities for logbook recording within these two areas of practice endorsement, with 16 clinical psychology and 30 clinical neuropsychology activities endorsed. There is a need to better clarify the rationale and principles for recording Direct Client Activities across areas of practice endorsement, to inform ongoing practices in these areas. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Comparing associations of handgrip strength and chair stand performance with all-cause mortality—implications for defining probable sarcopenia: the Tromsø Study 2015–2020.
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Johansson, Jonas, Grimsgaard, Sameline, Strand, Bjørn Heine, Sayer, Avan A., and Cooper, Rachel
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MORTALITY ,SARCOPENIA ,PROPORTIONAL hazards models ,ACID-base imbalances - Abstract
Background: Widely adopted criteria suggest using either low handgrip strength or poor chair stand performance to identify probable sarcopenia. However, there are limited direct comparisons of these measures in relation to important clinical endpoints. We aimed to compare associations between these two measures of probable sarcopenia and all-cause mortality. Methods: Analyses included 7838 community-dwelling participants (55% women) aged 40–84 years from the seventh survey of the Tromsø Study (2015–2016), with handgrip strength assessed using a Jamar + Digital Dynamometer and a five-repetition chair stand test (5-CST) also undertaken. We generated sex-specific T-scores and categorised these as "not low", "low", and "very low" handgrip strength or 5-CST performance. Cox Proportional Hazard regression models were used to investigate associations between these two categorised performance scores and time to death (up to November 2020 ascertained from the Norwegian Cause of Death registry), adjusted for potential confounders including lifestyle factors and specific diseases. Results: A total of 233 deaths occurred (median follow-up 4.7 years) with 1- and 5-year mortality rates at 3.1 (95% confidence interval [CI] 2.1, 4.6) and 6.3 (95% CI 5.5, 7.2) per 1000 person-years, respectively. There was poor agreement between the handgrip strength and 5-CST categories for men (Cohen's kappa [κ] = 0.19) or women (κ = 0.20). Fully adjusted models including handgrip strength and 5-CST performance mutually adjusted for each other, showed higher mortality rates among participants with low (hazard ratio [HR] 1.22, 95% CI 0.87, 1.71) and very low (HR 1.68, 95% CI 1.02, 2.75) handgrip strength compared with the not low category. Similar associations, although stronger, were seen for low (HR 1.88, 95% CI 1.38, 2.56) and very low (HR 2.64, 95% CI 1.73, 4.03) 5-CST performance compared with the not low category. Conclusions: We found poor agreement between T-score categories for handgrip strength and 5-CST performance and independent associations with mortality. Our findings suggest that these tests identify different people at risk when case-finding probable sarcopenia. As discussions on an international consensus for sarcopenia definitions proceed, testing both handgrip strength and chair stand performance should be recommended rather than viewing these as interchangeable assessments. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Trends in prevalence, treatment and control of hypertension in 38,825 adults over 36 years in Tromsø prospective study.
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Desai, Trishna, Clarke, Robert, Ross, Stephanie, Grimsgaard, Sameline, Njølstad, Inger, and Lewington, Sarah
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CARDIOVASCULAR disease prevention ,HYPERTENSION epidemiology ,HYPERTENSION ,SYSTOLIC blood pressure ,AGE distribution ,PUBLIC health ,SURVEYS ,SEX distribution ,DESCRIPTIVE statistics ,RESEARCH funding ,LONGITUDINAL method ,ADULTS - Abstract
Aims/Background: Serial blood pressure surveys in cohort studies can inform public health policies to control blood pressure for prevention of cardiovascular diseases. Methods: Mean levels of systolic blood pressure (SBP) were collected in six sequential surveys, involving 38,825 individuals aged 30–79 years (51% female), between 1979 and 2015 in the Tromsø Study in Norway. Mean levels of SBP, prevalence of hypertension and use of blood pressure-lowering treatment were estimated by age, sex and calendar year of survey. Results: Age-specific mean levels of SBP in each decade of age increased by 20–25 mmHg in men and 30–35 mmHg in women and the prevalence of hypertension increased from 25% to 75% among adults aged 30–79 years. Among successive cohorts of adults aged 40–49 years at the time of the six surveys between 1979 and 2015, the mean levels of SBP declined by about 10 mmHg and the prevalence of hypertension declined from 46% to 25% in men and from 30% to 14% in women. The proportion of individuals with hypertension who were treated increased sixfold (from 7% to 42%) between 1979 and 2015, and the proportion of adults with hypertension that were successfully controlled also increased sixfold from 10% to 60% between 1979 and 2015. Conclusions: Although this study demonstrated a halving in the age-specific prevalence of hypertension in men and women and a sixfold increase in treatment and control of hypertension, the burden of hypertension remains high among older people in Norway. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Association between neighborhood health behaviors and body mass index in Northern Norway: evidence from the Tromsø Study.
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Sari, Emre, Moilanen, Mikko, Bambra, Clare, Grimsgaard, Sameline, and Njølstad, Inger
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OBESITY ,LEISURE ,CONFIDENCE intervals ,LIFE course approach ,PHYSICAL activity ,HEALTH behavior ,DESCRIPTIVE statistics ,DISEASE prevalence ,RESEARCH funding ,BODY mass index ,RESIDENTIAL patterns ,NEIGHBORHOOD characteristics ,SECONDARY analysis - Abstract
Aim: The prevalence of overweight and obesity has risen rapidly worldwide, and the ongoing obesity pandemic is one of the most severe public health concerns in modern society. The average body mass index (BMI) of people living in Northern Norway has also steadily increased since the late 1970s. This study aimed to understand how individuals' health behavior is associated with the general health behavior of the people in their neighborhood. Methods: Using the population-based Tromsø Study, we examined the life course association between average leisure time physical activity at the neighborhood level and the BMI of individuals living in the same neighborhood. We used a longitudinal dataset following 25,604 individuals living in 33 neighborhoods and performed a linear mixed-effects analysis. Results: The results showed that participants living in neighborhoods whose residents were more physically active during their leisure time, were likely to have a significantly lower BMI (−0.9 kg/m², 95% CI −1.5 to −0.4). Also, individuals living in neighborhoods whose residents were doing mainly manual work, had significantly higher BMIs (0.7 kg/m², 95% CI 0.4−1.0). Conclusions: Our results showed a strong association between the average leisure time physical activity level of neighborhood residents and the higher BMI levels of residents of the same neighborhood. [ABSTRACT FROM AUTHOR]
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- 2023
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8. Data from national health registers as endpoints for the Tromsø Study: Correctness and completeness of stroke diagnoses.
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Varmdal, Torunn, Løchen, Maja-Lisa, Wilsgaard, Tom, Njølstad, Inger, Nyrnes, Audhild, Grimsgaard, Sameline, and Mathiesen, Ellisiv B.
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STROKE diagnosis ,REPORTING of diseases ,DATA quality ,PREDICTIVE tests ,CONFIDENCE intervals ,CARDIOVASCULAR diseases ,DESCRIPTIVE statistics ,SENSITIVITY & specificity (Statistics) ,DIAGNOSTIC errors ,EPIDEMIOLOGICAL research - Abstract
Aim: To assess whether stroke diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for the Tromsø Study, a population-based epidemiological study. Method: Using the Tromsø Study Cardiovascular Disease Register for 2013–2014 as the gold standard, we calculated correctness (defined as positive predictive value, PPV) and completeness (defined as sensitivity) of stroke cases in four different data subsets derived from the Norwegian Patient Register and the Norwegian Stroke Register. We calculated the sensitivity and PPV with 95% confidence intervals (CIs) assuming a normal approximation of the binomial distribution. Results: In the Norwegian Stroke Register we found a sensitivity of 79.8% (95% CI 74.2–85.4) and a PPV of 97.5% (95% CI 95.1–99.9). In the Norwegian Patient Register the sensitivity was 86.4% (95% CI 81.6–91.1) and the PPV was 84.2% (95% CI 79.2–89.2). The overall highest levels were found in a subset based on a linkage between the Norwegian Stroke Register and the Norwegian Patient Register, with a sensitivity of 88.9% (95% CI 84.5–93.3), and a PPV of 89.3% (95% CI 85.0–93.6). Conclusions: Data from the Norwegian Patient Register and from the linked data set between the Norwegian Patient Register and the Norwegian Stroke Register had acceptable levels of correctness and completeness to be considered as endpoint sources for the Tromsø Study Cardiovascular Disease Register. The benefits of using data from national registers as endpoints in epidemiological studies must be weighed against the impact of potentially decreased data quality. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project.
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Di Castelnuovo, Augusto, Bonaccio, Marialaura, Costanzo, Simona, McElduff, Patrick, Linneberg, Allen, Salomaa, Veikko, Männistö, Satu, Ferrières, Jean, Dallongeville, Jean, Thorand, Barbara, Brenner, Hermann, Ferrario, Marco, Veronesi, Giovanni, Tamosiunas, Abdonas, Grimsgaard, Sameline, Drygas, Wojciech, Malyutina, Sofia, Söderberg, Stefan, Nordendahl, Maria, and Kee, Frank
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MORTALITY ,ALCOHOL drinking ,EDUCATIONAL attainment ,BEVERAGES ,DEATH rate ,ALCOHOL-induced disorders - Abstract
The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1–10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74–1.02), 11% (HR = 0.89; 0.84–0.95) and 5% (HR = 0.95; 0.89–1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82–1.25), 10% (HR = 1.10; 1.02–1.19) and 17% (HR = 1.17; 1.09–1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016.
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Albrektsen, Grethe, Wilsgaard, Tom, Heuch, Ivar, Løchen, Maja-Lisa, Thelle, Dag Steinar, Njølstad, Inger, Grimsgaard, Sameline, and Bønaa, Kaare Harald
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- 2023
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11. Patient and public involvement in health research in Norway: a survey among researchers and patient organisations.
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Aas, Sigve Nyvik, Distefano, Marita Borg, Pettersen, Ingvild, Gravrok, Berit, Nordvoll, Laila Yvonne, Bjaastad, Jon Fauskanger, and Grimsgaard, Sameline
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PUBLIC health research ,INFRASTRUCTURE (Economics) ,BUDGET ,MEDICAL research ,TRUST - Abstract
Background: Patient and public involvement (PPI) in health research may improve both the relevance and quality of the research. There is however a lack of research investigating the experiences, attitudes and barriers towards PPI in clinical research in Norway. The Norwegian Clinical Research Infrastructure Network therefore conducted a survey among researchers and PPI contributors aiming to investigate experiences with PPI and identify current challenges for successful involvement. Methods: Two survey questionnaires were developed and distributed in October and November 2021. The survey targeting 1185 researchers was distributed from the research administrative system in the Regional Health Trusts. The survey targeting PPI contributors was distributed through Norwegian patient organisations, regional and national competence centers. Results: The response rate was 30% among researchers and was unobtainable from PPI contributors due to the survey distribution strategy. PPI was most frequently used in the planning and conduct of the studies, and less utilized in dissemination and implementation of results. Both researchers and user representatives were generally positive to PPI, and agreed that PPI might be more useful in clinical research than in underpinning research. Researchers and PPI contributors who reported that roles and expectations were clarified in advance, were more likely to experience a common understanding of roles and responsibilities in the research project. Both groups pointed to the importance of earmarked funding for PPI activities. There was a demand for a closer collaboration between researchers and patient organisations to develop accessible tools and effective models for PPI in health research. Conclusions: Surveys among clinical researchers and PPI contributors indicate overall positive attitudes towards PPI in clinical research. However, more resources, such as budget, time, and accessible tools, are needed. Clarifying roles and expectations, and creating new PPI models under resource constraints can enhance its effectiveness. PPI is underutilized in disseminating and implementing research results, presenting an opportunity for improving healthcare outcomes. Plain English summary: Patient and public involvement (PPI) in health research can make the research more relevant and of better quality. However, in Norway, there has not been much research on the experiences, attitudes, and barriers related to PPI in clinical research. To address this gap, we conducted a survey among researchers and PPI contributors to understand their experiences and identify current challenges. We found that PPI was most common during planning and execution of studies. PPI was less used in the process of sharing the results from the studies, and in the process of putting the findings into practice. Those who reported that roles and expectations were clarified in advance were more likely to have a shared understanding of their roles and responsibilities in the research project. Both groups emphasized the importance of funding for PPI activities. There was also a desire for closer collaboration between researchers and patient organisations to develop accessible tools and for PPI. In summary, the survey revealed a generally positive attitude towards PPI in health research. However, more resources, such as budget, time, and accessible tools, are needed. Clarification of roles and expectations also stand out a crucial part of the PPI process, and should receive much attention in all research projects where PPI is used. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Overvåkning av ikke-smittsomme sykdommer.
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NÆSS, ØYVIND, KROKSTAD, STEINAR, GRIMSGAARD, SAMELINE, LARSEN, INGER KRISTIN, MEYER, HAAKON E., and NYSTAD, WENCHE
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- 2023
13. 15–20 Year Follow-up After Wrist Arthroplasty Surgery – Revisiting the Development and Introduction of a New Prototype Concept for Total Wrist Arthroplasty.
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REIGSTAD, Ole, HOLM-GLAD, Trygve, KORSLUND, Johanne, GRIMSGAARD, Christian, THORKILDSEN, Rasmus, and RØKKUM, Magne
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WRIST surgery ,TOTAL shoulder replacement ,WRIST ,ARTHROPLASTY ,GRIP strength ,PAIN management - Abstract
Background: Wrist arthroplasties have not achieved clinical outcomes comparable to those of shoulders and knees, being offered low-demand patients due to a high failure rate. In the 90s, there were no wrist arthroplasties available for high-demand patients. An experimental setup for the development of a new wrist arthroplasty intended for all wrist patients were done. A long-term final follow-up to evaluate the performance of the experimental arthroplasty was performed. Methods: A novel uncemented modular wrist prosthesis with conical threaded fixation, metal-on-metal coupling and ball-and-socket articulation was developed. In an experimental study, eight patients (7 men, 53 years of age) were operated between 2001 and 2003, to treat non-inflammatory primary or secondary osteoarthritis. Published mid-term results (7–9 years) demonstrated satisfactory function, but two arthroplasties were converted to arthrodesis due to infection. Results: At final follow-up 15–20 years after primary surgery, the remaining six patients still had a wrist arthroplasty (in three the original) in situ. The clinical results were good. Low pain (median = 0), Quick Disability of Arm, Shoulder and Hand (QDASH median 11) and Patient Rated Wrist and Hand Evaluation (PRWHE median = 14) scores were reported. Wrist active range of motion (AROM) was 64% and grip strength 86% compared to the opposite side. None regretted choosing arthroplasty knowing the outcome. Conclusions: Despite technical errors and the implementation of an incomplete prototype, this new concept for arthroplasty has demonstrated promising long-term fixation, a stable articulation with good range of motion, satisfactory function and pain reduction in high-demand patients. Level of Evidence: Level IV (Therapeutic) [ABSTRACT FROM AUTHOR]
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- 2022
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14. The seventh survey of the Tromsø Study (Tromsø7) 2015–2016: study design, data collection, attendance, and prevalence of risk factors and disease in a multipurpose population-based health survey.
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Hopstock, Laila A., Grimsgaard, Sameline, Johansen, Heidi, Kanstad, Kristin, Wilsgaard, Tom, and Eggen, Anne Elise
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PUBLIC health surveillance ,BLOOD pressure ,ECHOCARDIOGRAPHY ,CARDIOVASCULAR diseases risk factors ,PHOTON absorptiometry ,ANTHROPOMETRY ,ORAL health ,INTERVIEWING ,PULSE oximetry ,MEDICAL screening ,COGNITION ,ACCELEROMETERS ,RISK assessment ,HEALTH behavior ,QUESTIONNAIRES ,BODY movement ,OBSTRUCTIVE lung diseases ,DISEASE prevalence ,DESCRIPTIVE statistics ,POPULATION health ,PULSE (Heart beat) ,EYE examination - Abstract
Aims: The Tromsø Study is an ongoing population-based health study in Tromsø, Norway, initiated in 1974. The purpose of the seventh survey (Tromsø7) 2015–2016 was to advance the population risk factor surveillance and to collect new types of data. We present the study design, data collection, attendance, and prevalence of risk factors and disease. Methods: All inhabitants in Tromsø municipality, Norway, aged 40 years and older (N =32,591) were invited to a health screening including extensive questionnaires, face-to-face interviews, biological sampling (blood, urine, saliva, nasal/throat swabs, faeces), measurements (anthropometry, blood pressure, pulse, pulse oximetry) and clinical examinations (pain sensitivity, echocardiography, cognitive, physical, and lung function, accelerometer measurements, eye examinations, carotid ultrasound, electrocardiography, dual-energy X-ray absorptiometry, and heart, lung and carotid auscultation). New research areas in this round were dental and oral health examinations, collection of faecal samples for studies of normal bacterial flora and antibiotic resistance, and 24-hour urine samples for examination of sodium and iodine intakes. Results: Attendance was 65% (N =21,083), and was higher in women, age group 50–79 years, previous attenders, and Norwegian-born individuals. Cardiovascular risk factor levels and prevalence of chronic obstructive lung disease decreased since the last survey, while the prevalence of obesity and diabetes increased. Conclusions: Attendance was stable from the sixth survey. Interaction with participants might be key to maintain participation. Favourable trends in risk factors continue, except for a continued increase in obesity. Both new data collection technology and traditional physical examinations will be crucial for the impact of future population studies. [ABSTRACT FROM AUTHOR]
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- 2022
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15. Polar Vantage and Oura Physical Activity and Sleep Trackers: Validation and Comparison Study.
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Henriksen, André, Svartdal, Frode, Grimsgaard, Sameline, Hartvigsen, Gunnar, and Hopstock, Laila Arnesdatter
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PHYSICAL activity ,ACCELEROMETERS ,PHYSICAL fitness ,CONSUMERS ,STATISTICAL correlation - Abstract
Background: Consumer-based activity trackers are increasingly used in research, as they have the potential to promote increased physical activity and can be used for estimating physical activity among participants. However, the accuracy of newer consumer-based devices is mostly unknown, and validation studies are needed. Objective: The objective of this study was to compare the Polar Vantage watch (Polar Electro Oy) and Oura ring (generation 2; Ōura Health Oy) activity trackers to research-based instruments for measuring physical activity, total energy expenditure, resting heart rate, and sleep duration in free-living adults. Methods: A total of 21 participants wore 2 consumer-based activity trackers (Polar watch and Oura ring), an ActiGraph accelerometer (ActiGraph LLC), and an Actiheart accelerometer and heart rate monitor (CamNtech Ltd) and completed a sleep diary for up to 7 days. We assessed Polar watch and Oura ring validity and comparability for measuring physical activity, total energy expenditure, resting heart rate (Oura), and sleep duration. We analyzed repeated measures correlations, Bland-Altman plots, and mean absolute percentage errors. Results: The Polar watch and Oura ring values strongly correlated (P<.001) with the ActiGraph values for steps (Polar: r=0.75, 95% CI 0.54-0.92; Oura: r=0.77, 95% CI 0.62-0.87), moderate-to-vigorous physical activity (Polar: r=0.76, 95% CI 0.62-0.88; Oura: r=0.70, 95% CI 0.49-0.82), and total energy expenditure (Polar: r=0.69, 95% CI 0.48-0.88; Oura: r=0.70, 95% CI 0.51-0.83) and strongly or very strongly correlated (P<.001) with the sleep diary–derived sleep durations (Polar: r=0.74, 95% CI 0.56-0.88; Oura: r=0.82, 95% CI 0.68-0.91). Oura ring–derived resting heart rates had a very strong correlation (P<.001) with the Actiheart-derived resting heart rates (r=0.9, 95% CI 0.85-0.96). However, the mean absolute percentage error was high for all variables except Oura ring–derived sleep duration (10%) and resting heart rate (3%), which the Oura ring underreported on average by 1 beat per minute. Conclusions: The Oura ring can potentially be used as an alternative to the Actiheart to measure resting heart rate. As for sleep duration, the Polar watch and Oura ring can potentially be used as replacements for a manual sleep diary, depending on the acceptable error. Neither the Polar watch nor the Oura ring can replace the ActiGraph when it comes to measuring steps, moderate-to-vigorous physical activity, and total energy expenditure, but they may be used as additional sources of physical activity measures in some settings. On average, the Polar Vantage watch reported higher outputs compared to those reported by the Oura ring for steps, moderate-to-vigorous physical activity, and total energy expenditure. [ABSTRACT FROM AUTHOR]
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- 2022
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16. Treatment target achievement after myocardial infarction and ischaemic stroke: cardiovascular risk factors, medication use, and lifestyle: the Tromsø Study 2015–16.
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Hopstock, Laila A, Morseth, Bente, Cook, Sarah, Eggen, Anne Elise, Grimsgaard, Sameline, Lundblad, Marie W, Løchen, Maja-Lisa, Mathiesen, Ellisiv, Nilsen, Amalie, and Njølstad, Inger
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- 2022
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17. Progressing arthrosis and a high conversion rate 11 (4–19) years after four corner fusion.
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Reigstad, Ole, Holm-Glad, Trygve, Dovland, Preben, Korslund, Johanne, Grimsgaard, Christian, Thorkildsen, Rasmus D., and Røkkum, Magne
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BONE grafting ,PAIN management ,AUTOTRANSPLANTATION ,RANGE of motion of joints ,COMPUTED tomography ,ARTHRODESIS - Abstract
Four corner fusion (4CF) is a limited wrist arthrodesis offered to patients with painful wrists due to scaphoid non-union advanced collapse (SNAC) or scapho-lunate advanced collapse (SLAC). A retrospective study of 42 wrists (in 36 patients), operated with 4CF using K-wires and autologous bone graft followed up after 11 (4–19) years was performed, 25 were male and mean age at surgery was 51 (22–71) years. During the follow-up period, 13 wrists were converted to total wrist arthrodesis or wrist arthroplasty, and one is scheduled for conversion (14/42, 33%) due to non-union (3), DISI and progressing arthrosis (7) or progressing arthrosis (4). Non-union was seen in 3/42 (93%) wrists, all were later converted. At the final follow-up, the patients reported residual pain, VAS = 15 and 36 at rest and activity, respectively, and QDASH/PRWHE = 32 and 31, respectively. Active range of motion (AROM) was 38% and grip-strength was 76% compared to the uninjured side. Degenerative changes were seen in 88% on CT scans at follow-up. 4CF renders an acceptable pain reduction and function in the majority of patients, but increased degeneration and a high number of conversions after a longer follow-up time is concerning. [ABSTRACT FROM AUTHOR]
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- 2021
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18. Secular and longitudinal trends in body composition: The Tromsø Study, 2001 to 2016.
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Lundblad, Marie Wasmuth, Johansson, Jonas, Jacobsen, Bjarne K., Grimsgaard, Sameline, Andersen, Lene Frost, Wilsgaard, Tom, and Hopstock, Laila A.
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BODY composition ,ADIPOSE tissues ,DUAL-energy X-ray absorptiometry ,ABDOMINAL adipose tissue ,AGE groups - Abstract
Objective: Overweight, defined as excessive fat mass, is a long‐standing worldwide public health challenge. Traditional anthropometric measures used to identify overweight and obesity do not assess body composition. The aim of this study was to examine population trends in general and abdominal fat mass during the past two decades. Methods: This study included participants from one or more consecutive surveys of the population‐based Tromsø Study, including Tromsø 5 (conducted in 2001, n = 1,662, age 40‐84 years), Tromsø 6 (2007‐2008, n = 901, age 40‐88 years), and Tromsø 7 (2015‐2016, n = 3,670, age 40‐87 years), with total body dual‐energy x‐ray absorptiometry scans. Trends in total fat and visceral adipose tissue (VAT) were analyzed by generalized estimation equation models in strata of sex and age groups. Results: Total fat and VAT mass increased during 2001 to 2016, with a larger increase during 2007 to 2016 than from 2001 to 2007 and among the youngest age group (40‐49 years), particularly in women. Women had higher total fat mass than men, whereas men had higher VAT mass than women. Conclusions: General and abdominal dual‐energy x‐ray absorptiometry‐derived fat mass increased during the past two decades in this general population. Of particular concern is the more pronounced increase in the past decade and in the younger age groups. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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19. Complex lifestyle intervention among inactive older adults with elevated cardiovascular disease risk and obesity: a mixed-method, single-arm feasibility study for RESTART—a randomized controlled trial.
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Deraas, Trygve S., Hopstock, Laila, Henriksen, Andre, Morseth, Bente, Sand, Anne Sofie, Njølstad, Inger, Pedersen, Sigurd, Sagelv, Edvard, Johansson, Jonas, and Grimsgaard, Sameline
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OLDER people ,CARDIOVASCULAR diseases ,CARDIOVASCULAR diseases risk factors ,RANDOMIZED controlled trials ,OBESITY ,NUTRITION counseling ,COACHING psychology ,SPORTS psychology - Abstract
Background: Physical inactivity and obesity are global public health challenges. Older adults are important to target for prevention and management of disease and chronic conditions. However, many individuals struggle with maintaining increased physical activity (PA) and improved diet. This feasibility study provides the foundation for the RESTART trial, a randomized controlled trial (RCT) to test a complex intervention to facilitate favourable lifestyle changes older adults can sustain. The primary objective of this study was to investigate study feasibility (recruitment, adherence, side-effects, and logistics) using an interdisciplinary approach. Methods: This 1-year prospective mixed-method single-arm feasibility study was conducted in Tromsø, Norway, from September 2017. We invited by mail randomly selected participants from the seventh survey of the Tromsø Study (2015–2016) aged 55–75 years with sedentary lifestyle, obesity, and elevated cardiovascular risk. Participants attended a 6-month complex lifestyle intervention program, comprising instructor-led high-intensive exercise and nutritionist- and psychologist-led counselling, followed by a 6-month follow-up. All participants used a Polar activity tracker for daily activity monitoring during the intervention. Participants were interviewed three times throughout the study. Primary outcome was study feasibility measures. Results: We invited potential participants (n=75) by mail of which 27 % (n=20) agreed to participate. Telephone screening excluded four participants, and altogether 16 participants completed baseline screening. The intervention and test procedures of primary and secondary outcomes were feasible and acceptable for the participants. There were no exercise-induced injuries, indicating that the intervention program is safe. Participants experienced that the dietary and psychological counselling were delivered too early in the intervention and in too close proximity to the start of the exercise program. Minor logistic improvements were implemented throughout the intervention period. Conclusion: This study indicates that it is feasible to conduct a full-scale RCT of a multi-component randomized intervention trial, based on the model of the present study. No dropouts due to exercise-induced injury indicates that the exercises were safe. While minor improvements in logistics were implemented during the intervention, we will improve recruitment and adherence strategies, rearrange schedule of intervention contents (exercise, diet, and psychology), as well as improve the content of the dietary and behavioural counselling to maximize outcome effects in the RESTART protocol. Trial registration: ClinicalTrials.gov Identifier: NCT03807323 Registered 16 January 2019 – retrospectively registered. [ABSTRACT FROM AUTHOR]
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- 2021
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20. Anthropometric measures are satisfactory substitutes for the DXA‐derived visceral adipose tissue in the association with cardiometabolic risk—The Tromsø Study 2015–2016.
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Lundblad, Marie W., Jacobsen, Bjarne K., Johansson, Jonas, Grimsgaard, Sameline, Andersen, Lene F., and Hopstock, Laila A.
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ADIPOSE tissues ,HDL cholesterol ,DUAL-energy X-ray absorptiometry ,BODY mass index ,GLYCOSYLATED hemoglobin ,DYSLIPIDEMIA - Abstract
Background: Body mass index (BMI) increases while cardiometabolic risk factors decrease in individuals in high‐income countries. This paradoxical observation raises the question of whether current measures of overweight and obesity properly identify cardiometabolic risk. Methods: A total of 3675 participants (59% women) aged 40–84 years with whole‐body dual‐energy x‐ray absorptiometry scans from the seventh survey of the Tromsø Study were included to examine the association between visceral adipose tissue (VAT) in grams and BMI, waist circumference (WC), waist‐to‐hip ratio (WHR), and waist‐to‐height ratio (WHtR). Further, their association with single cardiometabolic risk factors (blood pressure, triglycerides, total cholesterol, high‐density lipoprotein [HDL] cholesterol, glycated hemoglobin, high‐sensitivity C‐reactive protein), modified single components from the ATP Ⅲ criteria for metabolic syndrome (hypertension, diabetes, high triglycerides, and low HDL cholesterol), and metabolic syndrome were examined. Results: VAT mass was strongly correlated with BMI (r ≥ 0.77), WC (r ≥ 0.80), WHR (r ≥ 0.58), and WHtR (r ≥ 0.78). WC was the strongest predictor for VAT (area under the curve: 0.90). Compared to anthropometric measures, the associations between VAT and metabolic syndrome as well as single components of metabolic syndrome were statistically significantly stronger, but the clinical differences were likely minor. Conclusion: Although VAT mass showed statistically stronger associations with cardiometabolic risk compared to traditional anthropometrics, the clinical importance was likely small. Simple, clinically available tools seem to satisfactory substitute for VAT to identify cardiometabolic risk. [ABSTRACT FROM AUTHOR]
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- 2021
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21. Changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity and well-being in inactive women and men aged 57-74 years with obesity and cardiovascular risk – A 6-month complex lifestyle intervention with 6-month follow-up
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Hopstock, Laila A., Deraas, Trygve S., Henriksen, Andre, Martiny-Huenger, Torsten, and Grimsgaard, Sameline
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CARDIOVASCULAR diseases risk factors ,CARDIOVASCULAR fitness ,OLDER men ,OBESITY ,OLDER people ,BODY composition ,ADIPOSE tissues ,NUTRITION counseling - Abstract
A key challenge in lifestyle interventions is long-term maintenance of favorable lifestyle changes. Middle-aged and older adults are important target groups. The purpose of this analysis was to investigate changes in adiposity, physical activity, cardiometabolic risk factors, diet, physical capacity, and well-being, in inactive middle-aged and older women and men with obesity and elevated cardiovascular disease risk, participating in an interdisciplinary single-arm complex lifestyle intervention pilot study. Participants were recruited from the population-based Tromsø Study 2015–2016 with inclusion criteria age 55–74 years, body mass index (BMI) ≥30kg/m
2 , sedentary lifestyle, no prior myocardial infarction and elevated cardiovascular risk. Participants (11 men and 5 women aged 57–74 years) underwent a 6-month intervention of two 1-hour group-sessions per week with instructor-led gradually intensified exercise (endurance and strength), one individual and three 2-hour group counselling sessions with nutritionist (Nordic Nutrition Recommendations) and psychologist (Implementation intention strategies). We investigated changes in adiposity (weight, BMI, body composition, waist circumference), physical activity (self-reported and via physical activity trackers), cardiometabolic risk factors (blood pressure, HbA1c, blood lipids), diet (intake of energy, nutrients, foods), physical capacity (aerobic capacity, muscle strength), and psychological well-being, measured at baseline and end-of-intervention, using mean-comparison paired t-tests. Further, we investigated self-reported healthy lifestyle maintenance six months after end-of-intervention, and monthly changes in daily step count, moderate-to-vigorous physical activity (MVPA) and total energy expenditure. From baseline to end-of-intervention, there was a mean decrease in weight, BMI, fat mass, waist circumference, intake of total- and saturated fat, and increase in lean mass, lateral pulldown and leg press. We detected no changes in mean levels of physical activity, cardiometabolic risk factors or well-being. Six months after end-of-intervention, 25% responded healthy lifestyle achievement and maintenance, while objectively measured physical activity remained unchanged. The results are useful for development of a protocol for a full-scale trial. Trial registration: The study was registered at www.ClinicalTrials.gov registry (NCT03807323). [ABSTRACT FROM AUTHOR]- Published
- 2021
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22. Moderate‐to‐vigorous physical activity modifies the relationship between sedentary time and sarcopenia: the Tromsø Study 2015–2016.
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Johansson, Jonas, Morseth, Bente, Scott, David, Strand, Bjørn Heine, Hopstock, Laila A., and Grimsgaard, Sameline
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SARCOPENIA ,PHYSICAL activity ,OLDER people ,GRIP strength ,COGNITION disorders ,MUSCLE diseases ,MUSCLE strength - Abstract
Background: Sarcopenia is an age‐related muscle disease primarily characterized by reductions in muscle strength that increases the risk of falls, fractures, cognitive impairment, and mortality. Exercise is currently preferred in prevention and treatment, but it is unknown how different habitual physical activity and sedentary behaviour patterns associate with sarcopenia status. The purpose of the present study was to compare associations of these patterns with probable sarcopenia in older adults. Methods: In 3653 community‐dwelling participants (51% women) aged 60–84 years from the seventh survey of the Tromsø Study, we assessed objective physical activity and sedentary behaviour collected over 8 days (ActiGraph wGT3X‐BT Accelerometer), grip strength (Jamar+ Digital Dynamometer), five‐repetition chair stands, and self‐reported disease. We combined tertiles of sedentary (SED) time and moderate‐to‐vigorous physical activity (MVPA) to create nine different activity profiles (SEDHIGH, SEDMOD, and SEDLOW combined with MVPAHIGH, MVPAMOD, or MVPALOW). Multiple logistic regression models were used to examine how these profiles associated with probable sarcopenia, defined by low handgrip strength and/or slow chair stands time according to the revised European Working Group on Sarcopenia in Older People criteria. Results: Probable sarcopenia was present in 227 (6.2%) participants. Men with probable sarcopenia had on average 35.3 min more SED time and 20 min less MVPA compared with participants without sarcopenia (P < 0.01 for all), while women with probable sarcopenia only had 18 min less MVPA (P < 0.001). Compared with the SEDHIGH–MVPALOW reference activity profile (714.2 min SED/day and 10.4 min MVPA/day), the SEDHIGH–MVPAMOD profile (697.1 min SED/day and 31.5 min MVPA/day) had significantly lower odds ratio (OR) for probable sarcopenia (OR 0.17, 95% confidence interval [CI] 0.08–0.35), while the SEDLOW–MVPALOW profile (482.9 min SED/day and 11.0 min MVPA/day) did not (OR 0.72, 95% CI 0.47–1.11). These findings were not influenced by age, sex, smoking, or self‐reported diseases, and higher levels of MVPA did not further decrease ORs for probable sarcopenia. Conclusions: Older adults who achieve moderate amounts of MVPA have reduced odds for probable sarcopenia, even when they have high sedentary time. Those with low sedentary time did not have reduced odds for probable sarcopenia when they also had low amounts of MVPA. These findings need confirmation in longitudinal studies but suggest that interventions for preventing sarcopenia should prioritize increasing MVPA over reducing sedentary behaviour. [ABSTRACT FROM AUTHOR]
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- 2021
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23. Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study.
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Varmdal, Torunn, Mathiesen, Ellisiv B, Wilsgaard, Tom, Njølstad, Inger, Nyrnes, Audhild, Grimsgaard, Sameline, Bønaa, Kaare Harald, Mannsverk, Jan, and Løchen, Maja-Lisa
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DIAGNOSIS ,CARDIOVASCULAR diseases ,REPORTING of diseases - Abstract
Purpose: To assess whether acute myocardial infarction (MI) diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for a population-based, epidemiological study. Patients and Methods: Using the Tromsø Study Cardiovascular Disease Register for 2013– 2014 as gold standard, we calculated correctness (defined as positive predictive value (PPV)) and completeness (defined as sensitivity) of MI cases in the Norwegian Myocardial Infarction Register and the Norwegian Patient Register separately and in combination. We calculated the sensitivity and PPV with 95% confidence intervals using the Clopper-Pearson Exact test. Results: We identified 153 MI cases in the gold standard. In the Norwegian Myocardial Infarction Register, we found a PPV of 97.1% (95% confidence interval (CI) 92.8– 99.2) and a sensitivity of 88.2% (95% CI 82.0– 92.9). In the Norwegian Patient Register, the PPV was 96.3% (95% CI 91.6– 98.8) and the sensitivity was 85.6% (95% CI 79.0– 90.8). The combined dataset of the Norwegian Myocardial Infarction Register and the Norwegian Patient Register had a PPV of 96.6% (95% CI 92.1– 98.9) and a sensitivity of 91.5% (95% CI 85.9– 95.4). Conclusion: MI diagnoses in both the Norwegian Myocardial Infarction Register and the Norwegian Patient Register were highly correct and complete, and each of the registers could be considered as endpoint sources for the Tromsø Study. A combination of the two national registers seemed, however, to represent the most comprehensive data source overall. The benefits of using data from national registers as endpoints in epidemiological studies include faster, less resource-intensive access to nationwide data and considerably lower loss to follow-up, compared to manual data collection in a limited geographical area. [ABSTRACT FROM AUTHOR]
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- 2021
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24. Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015–2016.
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Lundblad, Marie W., Jacobsen, Bjarne K., Johansson, Jonas, De Lucia Rolfe, Emanuella, Grimsgaard, Sameline, and Hopstock, Laila A.
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Background. Reference values for visceral adipose tissue (VAT) are needed and it has been advocated that body composition measures depend on both the technique and methods applied, as well as the population of interest. We aimed to develop reference values for VAT in absolute grams (VATg), percent (VAT%), and as a kilogram-per-meters-squared index (VATindex) for women and men, and investigate potential differences between these measures and their associations with cardiometabolic risk factors (including metabolic syndrome (MetS)). Methods. In the seventh survey of the population-based Tromsø Study, 3675 participants (aged 40–84, 59% women) attended whole-body DXA scans (Lunar Prodigy GE) from where VAT was derived. We used descriptive analysis, correlations, receiver operating characteristics (ROC), and logistic regression to propose reference values for VAT and investigated VAT's association with cardiometabolic risk factors, MetS and single MetS components. Further, Youden's index was used to suggest threshold values for VAT. Results. VATg and VATindex increased until age 70 and then decreased, while VAT% increased with age across all age groups. VAT (all measurement units) was moderate to highly correlated and significantly associated with all cardiometabolic risk factors, except for total cholesterol. Associations between MetS, single MetS components, and VATg and VATindex were similar, and VAT% did not contribute any further to this association. Conclusion. These VAT reference values and thresholds, developed in a sample of adults of Norwegian origin, could be applied to other studies with similar populations using the same DXA device and protocols. The associations between VAT and cardiometabolic risk factors were similar across different measurement units of VAT. [ABSTRACT FROM AUTHOR]
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- 2021
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25. Dataset of fitness trackers and smartwatches to measuring physical activity in research.
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Henriksen, André, Woldaregay, Ashenafi Zebene, Muzny, Miroslav, Hartvigsen, Gunnar, Hopstock, Laila Arnesdatter, and Grimsgaard, Sameline
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SMARTWATCHES ,PHYSICAL activity ,CROWD funding ,ONLINE databases ,OPTICAL sensors ,BRAND name products - Abstract
Objectives: Accelerometer-based wrist-worn fitness trackers and smartwatches (wearables) appeared on the consumer market in 2011. Many wearable devices have been released since. The objective of this data paper is to describe a dataset of 423 wearables released before July 2017. Data description: We identified wearables and extracted information from six online and offline databases. We also visited websites for all identified companies/brands to identify additional wearables, as well as obtained additional information for each identified device. Twelve attributes were collected: wearable name, company/brand name, release year, country of origin, whether the wearable was crowd funded, form factor (fitness tracker or smartwatch), and sensors supported. Support for the following sensors were mapped: accelerometer, magnetometer, gyroscope, altimeter or barometer, global-positioning-system, and optical pulse sensor (i.e., photoplethysmograph). The search was conducted between May 15th and July 1st, 2017. The included data gives an overview of most in-scope wearables released before July 2017 and allows researchers to conduct additional analysis not performed in the related article. Further insights can be achieved by complementing this list with wearable models released after July 2017. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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26. Satisfactory function 12 years after triscaphoid arthrodesis for chronic scapholunate ligament injury.
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Reigstad, Ole, Grimsgaard, Christian, Holm-Glad, Trygve, Korslund, Johanne, Thorkildsen, Rasmus D., and Røkkum, Magne
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LIGAMENT injuries ,ARTHRODESIS ,RADIOGRAPHS ,RANGE of motion of joints ,GRIP strength ,VISUAL analog scale - Abstract
Scapholunate ligament (SLL) injury represents a hazard to the wrist and the treatment of these injuries has been the focus of much debate. We performed a long-term follow (>10 years) of triscaphoid arthrodesis for symptomatic chronic SLL injuries in 10 (8 men) patients 37 (22–49) years of age. All arthrodesis healed. One patient was converted to total wrist arthrodesis during the follow-up period, and three had minor additional surgeries. At final follow-up, the patients had reduced active range of motion (AROM, 55%) and grip strength (85%) compared to the opposite side, but reported low Quick Disability of Arm, Shoulder and Hand (QDASH) (11), Patient-Rated Wrist and Hand Evaluation (PRWHE) (25) and visual analog scale (VAS) pain scores (0 and 10 at rest and activity). Radiographs found minimal degenerative changes in four patients, while CT scans demonstrated changes in seven patients, in three of these scaphoid was subluxed on the rim of the radius. The patients working prior to surgery were working at follow-up. A triscaphoid arthrodesis for SLL renders a functional wrist function in most patients for many years and has postponed more extensive surgery like total wrist arthrodesis or wrist arthroplasty. The patients are still young, and the degenerative changes seen especially on CT scans warrants attention. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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27. No additional long-term effect of group vs individual family intervention in the treatment of childhood obesity-A randomised trial.
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Kokkvoll, Ane Sofie, Grimsgaard, Sameline, Flægstad, Trond, Andersen, Lars Bo, Ball, Geoff D. C., Wilsgaard, Tom, Njølstad, Inger, and Flaegstad, Trond
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CHILDHOOD obesity ,REGULATION of body weight ,OVERWEIGHT children ,BODY mass index ,PUBLIC hospitals - Abstract
Aim: Long-term evaluations of childhood obesity treatments are needed. We examined changes in weight and cardiometabolic risk 1 year after children completed individual family or group-based weight management interventions.Methods: In 2009-2010, 6- to 12-year-old children with overweight or obesity from Finnmark and Troms (Norway) were recruited after media coverage and randomised to 24 months of individual family (n = 49) or group intervention (n = 48). Individual family intervention included counselling by a paediatric hospital team and a public health nurse in the local community. Group intervention included meetings with other families and a multidisciplinary hospital team, weekly physical activity sessions and a family camp. The primary outcome body mass index (BMI) and cardiometabolic risk factors were analysed 12 months after intervention.Results: From baseline to 36 months, children's BMI increased 3.0 kg/m2 in individual family and 2.1 kg/m2 in group intervention (between-group -0.9kg/m2 , P = 0.096). Data were available from 62 children (64%). Between-group differences in C peptide (P = 0.01) were detected in favour of group intervention. Pooled data from both treatment groups showed continued decrease in BMI standard deviation score (P < 0.001).Conclusion: No between-group difference in BMI was observed 12 months after intervention. Both groups combined showed sustained decrease in BMI standard deviation score. [ABSTRACT FROM AUTHOR]- Published
- 2020
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28. Longitudinal changes in body composition and waist circumference by self-reported levels of physical activity in leisure among adolescents: the Tromsø study, Fit Futures.
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Aars, Nils Abel, Jacobsen, Bjarne K., Morseth, Bente, Emaus, Nina, and Grimsgaard, Sameline
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BODY composition ,PHYSICAL activity ,WAIST circumference ,LEAN body mass ,BODY mass index - Abstract
Background: It is not clear how physical activity affects body composition in adolescents. Physical activity levels are often reduced during this period, and the relative proportion of body fat mass and lean mass undergo natural changes in growing adolescents. We aimed to examine whether self-reported physical activity in leisure time at baseline or change in activity during follow-up affect changes in four measures of body composition; body mass index (kg/m
2 ), waist circumference, fat mass index (fat mass in kg/m2 ) and lean mass index (lean mass in kg/m2 ). Methods: We used data from the Tromsø Study Fit Futures, which invited all first year students in upper secondary high school in two municipalities in northern Norway in 2010–2011. They were reexamined in 2012–2013. Longitudinal data was available for 292 boys and 354 girls. We used multiple linear regression analyses to assess whether self-reported level of physical activity in leisure time at baseline predicted changes in body composition, and analysis of covariance to assess the effects of change in level of activity during follow-up on change in body composition. All analyses were performed sex-specific, and a p-value of < 0.05 was considered statistically significant. Results: There were no associations between self-reported leisure time physical activity in the first year of upper secondary high school and changes in any of the considered measure of body composition after 2 years of follow up, with the exception of waist circumference in boys (p = 0.05). In boys, change in fat mass index differed significantly between groups of activity change (p < 0.01), with boys adopting activity or remaining physically active having less increase in fat mass index than the consistently inactive. In girls, change in lean mass index differed significantly between groups of activity change (p = 0.04), with girls adopting physical activity having the highest increase. Conclusions: Self-reported leisure time physical activity does not predict changes in body composition in adolescents after 2 years of follow up. Change in the level of physical activity is associated with change in fat mass index in boys and lean mass index in girls. [ABSTRACT FROM AUTHOR]- Published
- 2019
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29. Physical activity levels in adults and elderly from triaxial and uniaxial accelerometry. The Tromsø Study.
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Sagelv, Edvard H., Ekelund, Ulf, Pedersen, Sigurd, Brage, Søren, Hansen, Bjørge H., Johansson, Jonas, Grimsgaard, Sameline, Nordström, Anna, Horsch, Alexander, Hopstock, Laila A., and Morseth, Bente
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PHYSICAL activity ,ACCELEROMETRY ,OLDER people ,ADULTS - Abstract
Introduction: Surveillance of physical activity at the population level increases the knowledge on levels and trends of physical activity, which may support public health initiatives to promote physical activity. Physical activity assessed by accelerometry is challenged by varying data processing procedures, which influences the outcome. We aimed to describe the levels and prevalence estimates of physical activity, and to examine how triaxial and uniaxial accelerometry data influences these estimates, in a large population-based cohort of Norwegian adults. Methods: This cross-sectional study included 5918 women and men aged 40–84 years who participated in the seventh wave of the Tromsø Study (2015–16). The participants wore an ActiGraph wGT3X-BT accelerometer attached to the hip for 24 hours per day over seven consecutive days. Accelerometry variables were expressed as volume (counts·minute
-1 and steps·day-1 ) and as minutes per day in sedentary, light physical activity and moderate and vigorous physical activity (MVPA). Results: From triaxial accelerometry data, 22% (95% confidence interval (CI): 21–23%) of the participants fulfilled the current global recommendations for physical activity (≥150 minutes of MVPA per week in ≥10-minute bouts), while 70% (95% CI: 69–71%) accumulated ≥150 minutes of non-bouted MVPA per week. When analysing uniaxial data, 18% fulfilled the current recommendations (i.e. 20% difference compared with triaxial data), and 55% (95% CI: 53–56%) accumulated ≥150 minutes of non-bouted MVPA per week. We observed approximately 100 less minutes of sedentary time and 90 minutes more of light physical activity from triaxial data compared with uniaxial data (p<0.001). Conclusion: The prevalence estimates of sufficiently active adults and elderly are more than three times higher (22% vs. 70%) when comparing triaxial bouted and non-bouted MVPA. Physical activity estimates are highly dependent on accelerometry data processing criteria and on different definitions of physical activity recommendations, which may influence prevalence estimates and tracking of physical activity patterns over time. [ABSTRACT FROM AUTHOR]- Published
- 2019
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30. Pragmatiske studier -- hva er det?
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LYNGBAKKEN, MAGNUS NAKREM, PAULSEN, AKSEL, SETHUPATHY, ASHWINI, HESSELBERG, ØYVIND, GRIMSGAARD, SAMELINE, and HAGEN, KNUT
- Published
- 2021
31. Self-reported physical activity during leisure time was favourably associated with body composition in Norwegian adolescents.
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Jacobsen, Bjarne K., Grimsgaard, Sameline, Aars, Nils Abel, Furberg, Anne‐Sofie, and Furberg, Anne-Sofie
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BODY composition ,PHYSICAL activity ,ADOLESCENCE ,LEISURE ,LEAN body mass - Abstract
Aim: We studied the cross-sectional association between self-reported physical activity and body composition in adolescents.Methods: The Norwegian Fit Futures Cohort Study was conducted in the Tromsø and Balsfjord municipalities during 2010-2011. All 1,117 students in their first year of upper secondary high school were invited to attend an examination at the Clinical Research Unit at the University Hospital of Northern Norway and 93% agreed. After exclusions, we analysed 945 participants (51% boys) with a mean age of 16.1 years (range 15.5-17.5 years) with valid measurements. The associations between self-reported weekly hours of physical activity during leisure time and four measures of body composition were explored using linear regression.Results: Self-reported physical activity was significantly associated with the fat mass index (p < 0.03) and lean mass index (p < 0.001) in both genders. The lean mass index increased with higher levels of activity and the fat mass index decreased. Physical activity was not associated with body mass index for either gender, but there was an inverse association with waist circumference in girls (p = 0.04).Conclusion: Physical activity was favourably associated with body composition in Norwegian adolescents and showed contrasting associations with the fat mass and lean mass indexes. [ABSTRACT FROM AUTHOR]- Published
- 2019
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32. Using Cloud-Based Physical Activity Data from Google Fit and Apple Healthkit to Expand Recording of Physical Activity Data in a Population Study.
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Henriksen, André, Hopstock, Laila Arnesdatter, Hartvigsen, Gunnar, and Grimsgaard, Sameline
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PHYSICAL activity measurement ,DATA analysis ,DETECTORS ,WEARABLE technology ,BODY area networks - Abstract
Large population studies are important sources for medical research. These studies are well planned, well organized, and costly. However, people record health data themselves using different sensors, which are mostly unplanned, unorganized and inexpensive. Nevertheless, self-recorded data might be an important supplement to population studies. The question is how to access and use this data. In the seventh survey of the Tromsø cohort study, questionnaires and accelerometers were used to collect data on physical activity (PA). We now plan to collect historical PA data from these participants, using mobile sensor data already stored in the cloud. We will examine the feasibility of this approach and the quality of this data. Objectively measured historical data will provide valuable insights in the potential and limitations of mobile sensors as new data collection tools in medical research. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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33. Patient and public involvement in health research: A Nordic perspective.
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Sand, Anne-Sofie, Grimsgaard, Sameline, and Pettersen, Ingvild
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INTERPROFESSIONAL relations ,MEDICAL care research ,PUBLIC health ,PATIENT participation ,STAKEHOLDER analysis - Abstract
Patient and public involvement (PPI) in health research is of increasing interest internationally, as well as being a means to enhance the quality and relevance of research. PPI was one of the main themes and parallel sessions at The Nordic Health Research and Innovation Networks in Oslo in 2017. In this short comment/debate article, we outline some of the experiences from the event. Importantly, there are many common challenges. More collaboration across the borders could ensure a broader range of experience in the field and provide better ways of developing and evaluating PPI in health research. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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34. Using Cloud-Based Physical Activity Data from Google Fit and Apple Healthkit to Expand Recording of Physical Activity Data in a Population Study.
- Author
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Henriksen, André, Hopstock, Laila Arnesdatter, Hartvigsen, Gunnar, and Grimsgaard, Sameline
- Abstract
Large population studies are important sources for medical research. These studies are well planned, well organized, and costly. However, people record health data themselves using different sensors, which are mostly unplanned, unorganized and inexpensive. Nevertheless, self-recorded data might be an important supplement to population studies. The question is how to access and use this data. In the seventh survey of the Tromsø cohort study, questionnaires and accelerometers were used to collect data on physical activity (PA). We now plan to collect historical PA data from these participants, using mobile sensor data already stored in the cloud. We will examine the feasibility of this approach and the quality of this data. Objectively measured historical data will provide valuable insights in the potential and limitations of mobile sensors as new data collection tools in medical research. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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35. Longitudinal and secular trends in total cholesterol levels and impact of lipid-lowering drug use among Norwegian women and men born in 1905-1977 in the population-based Tromsø Study 1979-2016.
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Arnesdatter Hopstock, Laila, Harald Bønaa, Kaare, Eggen, Anne Elise, Grimsgaard, Sameline, Jacobsen, Bjarne K., Løchen, Maja-Lisa, Mathiesen, Ellisiv B., Njølstad, Inger, and Wilsgaard, Tom
- Abstract
Objectives Elevated blood cholesterol is a modifiable risk factor for cardiovascular disease. Cholesterol level surveillance is necessary to study population disease burden, consider priorities for prevention and intervention and understand the effect of diet, lifestyle and treatment. Previous studies show a cholesterol decline in recent decades but lack data to follow individuals born in different decades throughout life. Methods We investigated changes in age-specific and birth cohort-specific total cholesterol (TC) levels in 43 710 women and men born in 1905-1977 (aged 20-95 years at screening) in the population-based Tromsø Study. Fifty-nine per cent of the participants had more than one and up to six repeated TC measurements during 1979-2016. Linear mixed models were used to test for time trends. Results Mean TC decreased during 1979-2016 in both women and men and in all age groups. The decrease in TC in age group 40-49 years was 1.2 mmol/L in women and 1.0 mmol/L in men. Both the 80th and the 20th percentile of the population TC distribution decreased in both sexes and all age groups. Longitudinal analysis showed that TC increased with age to a peak around middle age followed by a decrease. At any given age, TC significantly decreased with increase in year born. Lipid-lowering drug use was rare in 1994, increased thereafter, but was low (<3% in women and <5% in men) among those younger than 50 years in all surveys. Between 1994 and 2016, lipid-lowering drug treatment in individuals 50 years and older explained 21% and 28% of the decrease in TC levels in women and men, respectively. Conclusions We found a substantial decrease in mean TC levels in the general population between 1979 and 2016 in all age groups. In birth cohorts, TC increased with age to a peak around middle age followed by a decrease. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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36. Successful conversion of wrist prosthesis to arthrodesis in 11 patients.
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Reigstad, O., Holm-Glad, T., Thorkildsen, R., Grimsgaard, C., and Røkkum, M.
- Abstract
From 2001 to 2015, 11 wrists in 11 patients with osteoarthritis of the wrist had failed wrist arthroplasties, which were subsequently converted to arthrodesis using intercalated corticocancellous autograft from the iliac crest and fixation with an arthrodesis plate or a customized peg. Clinical and radiological bone union was achieved in all the operated wrists. At final follow-up of ten patients after 6 years, they had a substantial reduction in pain and improvement in daily function and grip strength compared with those before arthrodesis. We conclude from outcomes of this series that the conversion to arthrodesis after failed wrist arthroplasty is worthwhile and reliably improve wrist function over failed wrist arthroplasty. The results suggest that the patients who will have wrist arthroplasty can be assured that in case of failure the conversion to arthrodesis will produce outcomes comparable with those after primary arthrodesis.Level of evidence: IV [ABSTRACT FROM AUTHOR]
- Published
- 2017
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37. Longitudinal and Secular Trends in Blood Pressure Among Women and Men in Birth Cohorts Born Between 1905 and 1977.
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Hopstock, Laila Arnesdatter, Bønaa, Kaare Harald, Eggen, Anne Elise, Grimsgaard, Sameline, Jacobsen, Bjarne K., Løchen, Maja-Lisa, Mathiesen, Ellisiv B., Njølstad,, Inger, and Wilsgaard, Tom
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- 2015
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38. Longitudinal and Secular Trends in Blood Pressure Among Women and Men in Birth Cohorts Born Between 1905 and 1977.
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Arnesdatter Hopstock, Laila, Bønaa, Kaare Harald, Eggen, Anne Elise, Grimsgaard, Sameline, Jacobsen, Bjarne K., Løchen, Maja-Lisa, Mathiesen, Ellisiv B., Njølstad, Inger, and Wilsgaard, Tom
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- 2015
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39. Longitudinal and Secular Trends in Blood Pressure Among Women and Men in Birth Cohorts Born Between 1905 and 1977.
- Author
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Hopstock, Laila Arnesdatter, Bønaa, Kaare Harald, Eggen, Anne Elise, Grimsgaard, Sameline, Jacobsen, Bjarne K., Løchen, Maja-Lisa, Mathiesen, Ellisiv B., Njølstad, Inger, and Wilsgaard, Tom
- Published
- 2015
- Full Text
- View/download PDF
40. Longitudinal and Secular Trends in Blood Pressure Among Women and Men in Birth Cohorts Born Between 1905 and 1977.
- Author
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Hopstock, Laila Arnesdatter, Bønaa, Kaare Harald, Eggen, Anne Elise, Grimsgaard, Sameline, Jacobsen, Bjarne K., Løchen, Maja-Lisa, Mathiesen, Ellisiv B., Njølstad, Inger, and Wilsgaard, Tom
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- 2015
- Full Text
- View/download PDF
41. Undersøkelse og behandling av brudd og pseudartrose i skafoid.
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Reigstad, Ole, Thorkildsen, Rasmus, Grimsgaard, Christian, Melhuus, Knut, and Røkkum, Magne
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- 2015
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42. Health in overweight children: 2-year follow-up of Finnmark Activity School--a randomised trial.
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Kokkvoll, Ane, Grimsgaard, Sameline, Steinsbekk, Silje, Flægstad, Trond, and Njølstad, Inger
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OVERWEIGHT children ,HEALTH of school children ,BODY mass index ,CHILD psychology ,FOLLOW-up studies (Medicine) ,CLASSROOM activities ,HEALTH - Abstract
Objective To compare a comprehensive lifestyle intervention for overweight children performed in groups of families with a conventional single-family treatment. Two-year follow-up data on anthropometric and psychological outcome are presented. Design Overweight and obese children aged 6-12 years with body mass index (BMI) corresponding to ≥27.5 kg/m² in adults were randomised to multiplefamily (n=48) or single-family intervention (n=49) in a parallel design. Multiple-family intervention comprised an inpatient programme with other families and a multidisciplinary team, follow-up visits in their hometown, weekly physical activity and a family camp. Single-family intervention included counselling by paediatric nurse, paediatric consultant and nutritionist at the hospital and follow-up by a community public health nurse. Primary outcome measures were change in BMI kg/m² and BMI SD score after 2 years. Results BMI increased by 1.29 kg/m² in the multiplefamily intervention compared with 2.02 kg/m² in the single-family intervention (p=0.075). BMI SD score decreased by 0.20 units in the multiple-family group and 0.08 units in the single-family intervention group (p=0.046). A between-group difference of 2.4 cm in waist circumference (p=0.038) was detected. Pooled data from both treatment groups showed a significant decrease in BMI SD score of 0.14 units and a significant decrease in parent-reported and self-reported Strength and Difficulty Questionnaire total score of 1.9 units. Conclusions Two-year outcome showed no betweengroup difference in BMI. A small between-group effect in BMI SD score and waist circumference favouring multiple-family intervention was detected. Pooled data showed an overall improvement in psychological outcome measures and BMI SD score. Trial registration number NCT00872807 [ABSTRACT FROM AUTHOR]
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- 2015
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43. Single versus multiple-family intervention in childhood overweight--Finnmark Activity School: a randomised trial.
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Kokkvoll, Ane, Grimsgaard, Sameline, Ødegaard, Rønnaug, Flægstad, Trond, and Njølstad, Inger
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OVERWEIGHT children ,RANDOMIZED controlled trials ,BODY mass index ,PATIENT participation ,WAIST circumference ,HEALTH outcome assessment - Abstract
Objective: To compare a new comprehensive lifestyle programme performed in groups of families with overweight (included obese) children with a more conventional single-family programme. The study design and interim anthropometrical results after 12 months are presented. Design: Altogether 97 overweight and obese children aged 6-12 years with body mass index (BMI) corresponding to cut-off point ±27.5 in adults were included. Study participants were randomised to multiple-family intervention (MUFI) or single-family intervention (SIFI) in a parallel design. MUFI comprised a 3-day inpatient programme at the hospital with other families and a multidisciplinary team, follow-up visits in their hometown individually and in groups, organised physical activity twice weekly and a 4-day family camp after 6 months. SIFI comprised individual counselling by paediatric nurse, paediatric consultant and nutritionist at the hospital and follow-up by public health nurse in the community. Solution focused approach was applied in both interventions. Primary outcome measures were change in BMI kg/m² and BMI SD score (BMI SDS). Results: BMI increased by 0.37 units in the MUFI compared to 0.77 units in the SIFI ( p=0.18). BMI SDS decreased by 0.16 units in the MUFI group compared to 0.07 units in the SIFI group ( p=0.07). Secondary endpoint waist circumference decreased 0.94 cm in the multiple-family group and increased 0.95 cm in the single-family group, p=0.04. Conclusions: Interim analysis after 12 months showed no between-group difference in termsof BMI or BMI SDS. The MUFI group had a significant decrease in waist circumference compared to the SIFI group. [ABSTRACT FROM AUTHOR]
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- 2014
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44. Excellent Results After Bone Grafting and K-Wire Fixation for Scaphoid Nonunion Surgery in Skeletally Immature Patients: A Midterm Follow-up Study of 11 Adolescents After 6.9 Years.
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Reigstad, Ole, Thorkildsen, Rasmus, Grimsgaard, Christian, Reigstad, Astor, and Rokkum, Magne
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- 2013
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45. Serum level of under-carboxylated osteocalcin and bone mineral density in early menopausal Norwegian women.
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Emaus, Nina, Nguyen, Nguyen, Almaas, Bjørg, Berntsen, Gro, Center, Jacqueline, Christensen, Monika, Gjesdal, Clara, Grimsgaard, Anne, Nguyen, Tuan, Salomonsen, Laila, Eisman, John, and Fønnebø, Vinjar
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STATISTICAL correlation ,PREMATURE ovarian failure ,QUESTIONNAIRES ,RESEARCH funding ,MULTIPLE regression analysis ,BONE density ,RANDOMIZED controlled trials ,BLIND experiment ,PHYSICAL activity ,DATA analysis software ,DESCRIPTIVE statistics ,OSTEOCALCIN ,PHOTON absorptiometry - Abstract
Purpose: Serum level of under-carboxylated osteocalcin (ucOC) is considered a sensitive measure of vitamin K status, and ucOC levels are associated with bone mineral density (BMD) and fracture risk in elderly persons. The aim of this study was to assess the relationship between ucOC and BMD in early menopausal women. Methods: The data reported here come from the enrolment in a double-blinded placebo-controlled randomized trial comprising 334 healthy Norwegian women between 50 and 60 years, 1-5 years after menopause, not using warfarin or medication known to affect bone metabolism. Total hip, femoral neck, lumbar spine, and total body BMD and serum level of ucOC and total osteocalcin were measured, and information of lifestyle was collected through questionnaires. The association between ucOC and BMD at all measurement sites was assessed by multiple regression analyses adjusting for possible confounding variables. Results: The absolute serum level of ucOC was significantly and negatively associated with BMD at all measurements sites, both in univariate analyses ( p < 0.01) and in multivariate analyses adjusting for years since menopause, smoking status and weight ( p < 0.01). However, serum ucOC, expressed as percentage of the total osteocalcin level, was not associated with BMD at any site. Conclusions: Achievement of adequate vitamin K nutritional intake is important, but ucOC expressed as percentage of total osteocalcin levels as reflection of vitamin K status does not seem to play a central role in determining BMD levels in early menopausal women. [ABSTRACT FROM AUTHOR]
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- 2013
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46. SCAPHOID NON-UNIONS, WHERE DO THEY COME FROM? THE EPIDEMIOLOGY AND INITIAL PRESENTATION OF 270 SCAPHOID NON-UNIONS.
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Reigstad, Ole, Grimsgaard, Christian, Thorkildsen, Rasmus, Reigstad, Astor, and Røkkum, Magne
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CARPAL bones ,SCAPHOID bone ,EPIDEMIOLOGY ,OSTEOARTHRITIS ,DEGENERATION (Pathology) ,PSEUDARTHROSIS ,DISEASES - Abstract
Scaphoid injury and subsequent non-union is a well documented and researched subject. This article gives an overview of the epidemiology and results of the patients we have treated for scaphoid non-union at a University Hospital. 283 scaphoid non-unions in 268 patients (83% men) were operated upon, 230 as a primary and 47 as a secondary. The median age at time of surgery was 27 years. One-third of the non-unions were located in the proximal part of the scaphoid and the remaining two-thirds in the middle part. Of the 146 patients (55%) who contacted a doctor at the time of injury, 53 fractures where diagnosed (20%). Fourteen (5%) were operated primarily while 39 (15%) (seven dislocated) were immobilized in plaster casts. Thirty-two (12%) were under the age of 16 at the time of injury. The average time from the injury to the initial non-union surgery was 1.5 years with 2.8 years to the second procedure. The risk of osteoarthritis increased time from injury to surgery (both primary and secondary procedures). The greatest potential for the reduction of scaphoid non-union is an increased awareness amongst younger men. There is also potential for improved accuracy in the diagnosis of scaphoid fractures (better clinical tests, the use of radiographs, CTs and MRIs) in order to identify the fracture and evaluate dislocation at the initial injury. Early diagnosis and treatment of fractures and non-unions will reduce the development of degenerative wrist changes. [ABSTRACT FROM AUTHOR]
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- 2012
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47. Long-term results of scaphoid nonunion surgery: 50 patients reviewed after 8 to 18 years.
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Reigstad O, Grimsgaard C, Thorkildsen R, Reigstad A, and Rokkum M
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- 2012
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48. New concept for total wrist replacement.
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Reigstad, Astor, Reigstad, Ole, Grimsgaard, Christian, and Røkkum, Magne
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WRIST ,ARTIFICIAL organs ,OSTEOARTHRITIS treatment ,INFLAMMATION ,JOINT diseases - Abstract
Wrist prostheses have never achieved the sort of clinical outcomes found with those of hips and knees. We have developed a novel uncemented modular wrist prosthesis with screw fixation, metal-on-metal coupling, and ball-and-socket articulation. Eight patients admitted for wrist arthrodesis to treat primary or secondary osteoarthritis (not rheumatoid) were operated on. The prosthesis reduced the amount of bone removed and spared the distal radioulnar joint. After 7 to 9 years we found that the fixed centre of the ball-and-socket articulation provided good stability and mobility, and relief of pain and grip strength were satisfactory. We saw no luxations, metacarpal fractures or cut-outs, or mechanical failures of the implants. Two distal screws loosened (revised with new distal screws), and one early inflammation and one late infection occurred (revised to arthrodesis). We propose modifications to the implant with reduction in the diameter of the screws and the height of the threads, and rounding of the distal tip. The technique should include release of the third carpometacarpal joint, alignment of the capitate and the third metacarpal, and arthrodesis of the joint with bone chips. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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49. Depression in postmenopause: a study on a subsample of the Acupuncture on Hot Flushes Among Menopausal Women (ACUFLASH) study.
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Dørmænen A, Heimdal MR, Arfwedson Wang CE, and Grimsgaard AS
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- 2011
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50. Perioperative acupuncture and postoperative acupressure can prevent postoperative vomiting following paediatric tonsillectomy or adenoidectomy: a pragmatic randomised controlled trial.
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Liodden, Ingrid, Howley, Michael, Grimsgaard, Anne Sameline, Fønnebø, Vinjar Magne, Borud, Einar Kristian, Alraek, Terie, and Norheim, Arne Johan
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NAUSEA ,NAUSEA treatment ,VOMITING prevention ,VOMITING treatment ,TREATMENT of surgical complications ,ACUPRESSURE ,ACUPUNCTURE ,ADENOIDECTOMY ,AGE distribution ,ANALYSIS of variance ,COMPUTER software ,HEALTH outcome assessment ,RESEARCH funding ,SEX distribution ,STATISTICS ,TONSILLECTOMY ,LOGISTIC regression analysis ,DATA analysis ,RANDOMIZED controlled trials ,TREATMENT effectiveness ,CHILDREN ,PREVENTION - Abstract
Objective: To investigate the effectiveness of acupuncture and acupressure as supplements to standard treatment for postoperative vomiting in children undergoing tonsillectomy and/or adenoidectomy. Methods: A pragmatic, open, block-randomised controlled trial. The results were analysed according to the intention-to-treat principle. The study was conducted without extra resources in a normal setting at the day-surgery department of Lovisenberg Diakonale Hospital in Oslo. 154 children with an American Society of Anesthesiologists grade 1-2, weighing at least 10 kg, were included. Children with concomitant gastrointestinal diseases, emesis or antiemetic treatment <24 h preoperatively, rash or local infection over the actual acupuncture points were excluded together with patients whose parents' informed consent could not be obtained. The intervention group received acupuncture at pericardium 6 bilaterally, at a depth of approximately 0.7 cm with a median of 21 min during anaesthesia, followed by acupressure wristbands for 24 h and standard treatment. The control group received standard treatment. The primary end point was the occurrence of vomiting or retching during 24 h postoperatively. Results: Children in the acustimulation group experienced less retching and vomiting than the control group--46.8% versus 66.2% (p=0.015). The effect of acustimulation was specifically pronounced in girls and children aged 1-3 years. Conclusion: This trial indicates the effectiveness of acustimulation as an adjunct to standard treatment. The results should encourage and promote the implementation of acustimulation for postoperative vomiting in children undergoing adenoidectomy or tonsillectomy. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
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