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The editorial "Endocrine Disruptors in Gut Endocrinology" explores the complex interactions between the endocrine system, gut microbiota, and endocrine disruptors, highlighting their implications for human health. Endocrine disruptors, such as phthalates and bisphenol A, can interfere with hormone production and metabolism, potentially leading to various health issues. The research emphasizes the importance of understanding these interactions for the prevention and treatment of clinical conditions and diseases, showcasing advancements in personalized medicine and therapeutic strategies. Future research is crucial to further clarify these relationships and explore interventions like lifestyle modifications and probiotics to mitigate the negative health effects of endocrine disruptors. [Extracted from the article]

Natural fibre–polymer composites are widely used because they are economical and ecologically beneficial in a variety of applications. In order to improve its performance, this study focuses on examining the mechanical characteristics of an epoxy composite material that has been reinforced with banana fibre mats that have undergone NaOH treatment. Additionally, using various configurations both with and without eggshell powder (ESP), the compression moulding method was used to fabricate and investigate the impact of ESP on these mechanical qualities. The results showed that the composite with 25 weight percent banana fibre and 2.5 weight percent ESP had the maximum tensile strength (31.21 MPa), bending strength (33.69 MPa), and impact strength (2.84 kJ/m2). Strong interfacial adhesion between the banana and eggshell components was discovered via the microscopic examination of shattered surfaces. Notably, compared to untreated banana composites, the alkaline-treated banana materials showed fewer occurrences of pull-outs and fractures, leading to noticeably better mechanical performance. [ABSTRACT FROM AUTHOR]

Acute myocardial infarction (AMI) is due to ischemic heart or coronary artery disease that leads to artherosclerotic plaque rupture and thrombus. This blocks the coronary artery and restricts the blood access to the heart. Currently the cardiac protein used for diagnosis of AMI are Troponin I and Troponin T. Cardiac troponin (cTn) is detected in blood within 2-3 of cardiac injury and peak expression between 24 -48 hrs. No reliable markers are available for prediction of cardiac events leading to AMI. Previous studies show prognostic significance of cortisol in post AMI patients. An observational case-control study is done to find the association between cortisol and AMI. The aim of the study is to detect serum cortisol in CAD risk patients during AMI. The study aims to determine a cut off value for serum cortisol concentration to predict the event of AMI in CVD risk patients. A total of 315 samples from volunteers were analysed by Biochemical and Immunoassays. The samples based on the results are grouped as Risky, control, Suspected and AMI. A total of 116 samples are found as risky, 29 as susceptible, 86 as AMI and 84 as control samples. The results showed an elevated level of cortisol in AMI group. Statistical analysis by ROC test and Youden index determined the serum cortisol concentration as 13.76 ug/mL at 91% specificity and 61% sensitivity. The odds ratio for AMI is 2.8189 (95% CI 1.6255 to 4.8884) P =0.0002 and the Relative Risk Ratio is 1.9006 (95% CI 1.3450 to 2.6857) P=0.0003. [ABSTRACT FROM AUTHOR]

This study looks at how incorporating nanofiller into sisal/flax-fibre-reinforced epoxy-based hybrid composites affects their mechanical and water absorption properties. The green Al2O3 NPs are generated from neem leaves in a proportion of leaf extract to an acceptable aluminium nitrate combination. Both natural fibres were treated with different proportions of NaOH to eliminate moisture absorption. The following parameters were chosen as essential to achieving the objectives mentioned above: (i) 0, 5, 10, and 15% natural fibre concentrations; (ii) 0, 2, 4, and 6% aluminium powder concentrations; and (iii) 0, 1, 3, and 5% NaOH concentrations. Compression moulding was used to create the hybrid nanocomposites and ASTM standards were used for mechanical testing such as tension, bending, and impact. The findings reveal that combining sisal/flax fibre composites with nanofiller improved the mechanical features of the nanocomposite. The sisal and flax fibre hybridised successfully, with 10% fibres and 4% aluminium filler. The water absorption of the hybrids rose as the fibre weight % increased, and during the next 60 h, all of the specimens achieved equilibrium. The failed samples were examined using scanning electron Microscopic (SEM) images better to understand the composite's failure in the mechanical experimentations. Al2O3 NPs were confirmed through XRD, UV spectroscope and HPLC analysis. According to the HPLC results, the leaf's overall concentrations of flavonoids (gallocatechin, carnosic acid, and camellia) are determined to be 0.250 mg/g, 0.264 mg/g, and 0.552 mg/g, respectively. The catechin concentration is higher than the phenolic and caffeic acid levels, which could have resulted in a faster rate of reduction among many of the varying configurations, 4 wt.% nano Al2O3 particle, 10 wt.% flax and sisal fibres, as well as 4 h of NaOH with a 5 wt.% concentration, producing the maximum mechanical properties (59.94 MPa tension, 149.52 Mpa bending, and 37.9 KJ/m2 impact resistance). According to the results, it can be concluded that botanical nutrients may be used effectively in the manufacturing of nanomaterials, which might be used in various therapeutic and nanoscale applications. [ABSTRACT FROM AUTHOR]

Natural fiber-reinforced polymer composites are gaining in popularity due to recyclability and availability. This research investigates how oil palm shell (OPS) filler materials impact the interlaminar shear and the dynamic properties of flax fiber-reinforced hybrid composites under cryogenic circumstances. Filler materials in two different proportions (0, 2, 4, and 6 wt.% OPS) and 40 wt.% flax fibers were used to make composites. The OPS filler-filled polymeric materials were invented through typical hand lay-up. The hybrid materials were imperiled to liquid nitrogen for varying amounts of time after production (15 and 30 min). According to the findings, OPS nanoparticles can be used as natural rather than artificial fillers. Furthermore, loading 4 wt.% OPS nanoparticles into organic fabric-strengthened epoxy polymeric materials during 15 min of cryogenic settings resulted in the best interlaminar shear and dynamic performances. The storage and loss modulus of the flax/epoxy composites were improved by adding a 4% OPS nanofiller. The improvement can be ascribed to the hardness and stiffness of the additional OPS nanofillers. The 4% nano-OPS/flax/epoxy hybrid nanocomposite's damping factor was substantially reduced compared to the flax/epoxy composites. The OPS nanofiller limits the epoxy molecular chain's free segmental mobility, resulting in a lower damping factor and enhancing the adherence among flax fibers and the epoxy resin. The shattered specimen of the hybrid materials was investigated using a scanning electron microscope. [ABSTRACT FROM AUTHOR]

The characteristics of natural fiber reinforced composites such as light weight, non-abrasive, nonflammable, nontoxic, low cost and biodegradable have grabbed the attention of current researchers in the area of composites. The objective of this study is to examine the interlaminar shear strength of the polyester based wood and woven jute hybrid composite. To accomplish this objective, the following parameters such as (i) wood density, (ii) wood weight ratio, (iii) woven jute type, (iv) number of jute layers, (v) cryogenic treatment duration and (vi) alkaline treatment duration, each at three different levels were picked and optimized using the Taguchi method. The fibers were pretreated with 5% of NaOH solution for different length of time to reduce the moisture absorption. The L27 orthogonal array was selected for the chosen parameters and the required composite materials were fabricated using hand lay-up techniques. The fabricated composites were then subjected to cryogenic treatment by immersing in liquid nitrogen at 77 K for different period of time. The interlaminar shear strength of the fabricated hybrid composites was done according to ASTM standard. The morphological features and degree of dispersions of fibers into the matrix of the fabricated hybrid composites were further studied and discussed. [ABSTRACT FROM AUTHOR]

This investigation is carried out to understand the effects of water absorption on the mechanical properties of hybrid phenol formaldehyde (PF) composite fabricated with Areca Fine Fibres (AFFs) and Calotropis Gigantea Fibre (CGF). Hybrid CGF/AFF/PF composites were manufactured using the hand layup technique at varying weight percentages of fibre reinforcement (25, 35 and 45%). Hybrid composite having 35 wt.% showed better mechanical properties (tensile strength ca. 59 MPa, flexural strength ca. 73 MPa and impact strength 1.43 kJ/m2) under wet and dry conditions as compared to the other hybrid composites. In general, the inclusion of the fibres enhanced the mechanical properties of neat PF. Increase in the fibre content increased the water absorption, however, after 120 h of immersion, all the composites attained an equilibrium state. [ABSTRACT FROM AUTHOR]

Three pseudomonad strains (MKRh1, MKRh3, and MKRh4) isolated from rhizospheres showed a high growth potential in the presence of cadmium, with a minimal inhibitory concentration of 7 mM for cadmium chloride (CdCl2). Among them, isolate MKRh3 was specifically chosen as the most favorable cadmium-resistant plant growth-promoting rhizobacterium based on its higher 1-aminocyclopropane carboxylic acid deaminase activity, siderophore production, phosphate solubilization, and auxin synthesis and the in vivo growth increment of black gram plants. 16S ribosomal RNA gene sequencing identified MKRh3 as Pseudomonas aeruginosa. The effect of cadmium on black gram plants was studied in soil amended with a gradient of CdCl2 concentration and the toxicity was evident from stunted growth, poor rooting, and cadmium accumulation. Application of isolate MKRh3 by seed coating overcomes the cadmium toxicity; plants showed lessened cadmium accumulation, extensive rooting, and enhanced plant growth. Further research and development of this promising innate strategy for scale-up to higher-efficiency and large-scale application will be a potent tool to prevent accumulation of cadmium in plants, thereby ensuring food security for humans. [ABSTRACT FROM AUTHOR]

The present study is aimed at investigating the effect of hybridisation on Kevlar/E-Glass based epoxy composite laminate structures. Composites with 3 mm thickness and 16 layers of fibre (14 layers of E-glass centred and 2 outer layers of Kevlar) were fabricated using compression moulding technique. The fibre orientation of the Kevlar layers had 3 variations (0, 45 and 60°), whereas the E-glass fibre layers were maintained at 0° orientation. Tensile, flexural, impact (Charpy and Izod), interlaminar shear strength and ballistic impact tests were conducted. The ballistic test was performed using a gas gun with spherical hard body projectiles at the projectile velocity of 170 m/s. The pre- and post-impact velocities of the projectiles were measured using a high-speed camera. The energy absorbed by the composite laminates was further reported during the ballistic test, and a computerised tomographic scan was used to analyse the impact damage. The composites with 45° fibre orientation of Kevlar fibres showed better tensile strength, flexural strength, Charpy impact strength, and energy absorption. The energy absorbed by the composites with 45° fibre orientation was 58.68 J, which was 14% and 22% higher than the 0° and 60° oriented composites. [ABSTRACT FROM AUTHOR]

Natural fibre-based composites are replacing traditional materials in a wide range of structural applications that are used in different environments. Natural fibres suffer from thermal shocks, which affects the use of these composites in cold environment. Considering these, a goal was set in the present research to investigate the impact of cryogenic conditions on natural fibre composites. Composites were developed using polyester as matrix and jute-fibre and waste Teak saw-dust as reinforcement and filler, respectively. The effects of six parameters, viz., density of saw-dust, weight ratio of saw-dust, grade of woven-jute, number of jute layers, duration of cryogenic treatment of composite and duration of alkaline treatment of fibres on the mechanical properties of the composite was evaluated with an objective to maximise hardness, tensile, impact and flexural strengths. Taguchi method was used to design the experiments and response-surface methodology was used to model, predict and plot interactive surface plots. Results indicated that the duration of cryogenic treatment had a significant effect on mechanical properties, which was better only up to 60 min. The models were found to be statistically significant. The study concluded that saw-dust of density 300 kg/m3 used as a filler with a weight ratio of 13 wt.% and a reinforcement of a single layer of woven-jute-fibre mat of grade 250 gsm subjected to alkaline treatment for 4 h in a composite that has undergone 45 min of cryogenic treatment presented an improvement of 64% in impact strength, ca. 21% in flexural strength, ca. 158% in tensile strength and ca. 28% in hardness. [ABSTRACT FROM AUTHOR]