1. The burden of HPV-related diseases in Italy, 2001-12.
- Author
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Kuhdari, P., Previato, S., Giordani, M., Biavati, P., Ferretti, S., and Gabutti, G.
- Subjects
GENITAL warts ,PENILE tumors ,HEAD tumors ,NECK tumors ,CERVIX uteri tumors ,GENITOURINARY organ tumors ,ANAL tumors ,OROPHARYNGEAL cancer ,CONFIDENCE intervals ,PAPILLOMAVIRUS diseases ,DATA analysis software ,DESCRIPTIVE statistics ,DISEASE complications ,DISEASE risk factors ,TUMOR risk factors - Abstract
Background Human papillomavirus (HPV) infection is the main cause of cervical cancer and plays a relevant role in the development of genital warts and of the cancer of penis and anus, head/neck, oropharynx and genitourinary system. The aim of this study is the evaluation of hospitalizations due to HPV-related pathologies in 2001-12 in Italy. Methods The national hospital discharge forms were provided by the Ministry of Health. The HPV-related hospitalizations were identified using specific diagnostic codes, accordingly to the ICD-9-CM coding system. The proportion of hospitalizations of potentially HPV-related pathologies, obtained from the literature, was evaluated as well as the hospitalization rates (hr) and their trend over time. Results Uterine cervical cancer and CIN III accounted for 40% of hospitalizations (hr: 15.6/100 000 and 17.6/100 000, respectively). Head/neck and oropharynx pathologies accounted for 24.5% of cases (hr: 16/100 000 and 3.9/100 000, in males and females, respectively), followed by genital warts (17.3% of hospitalizations; hr: 7.5/100 000 in males and 8.52/100 000 in females), anal (8.1% of hospitalizations), genitourinary (7.7%) and penis cancers (2.2%). Conclusions The study, even if limited to the evaluation of hospitalizations, points out how HPV-related pathologies continue to be a relevant public health issue in Italy with a high impact on population. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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