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Purpose: To examine the molecular mechanism of radiation adaptive response (RAR) for the growth of cultured glial cells and to investigate the influence of ageing on the response. Materials and methods: Glial cells were cultured from young and older rats (1 and 24 months). RAR for the growth of glial cells conditioned with a low dose of X-rays and subsequently exposed to a high dose of X-rays was examined for cell number and BrdU incorporation. Involvement of the subcellular signalling pathway factors in RAR was investigated using their inhibitors, activators, and mutated and knockout glial cells. Results: RAR was observed in cells cultured from young rats but was not in cells from older animals. The inhibitors of protein kinase C (PKC) and DNA-dependent protein kinase (DNA-PK) or phosphatidylinositol 3-kinase (P13K) suppressed RAR. The activators of PKC instead of low-dose irradiation also caused RAR. Moreover, glial cells cultured from severe combined immunodeficiency (scid) mice (CB-17 scid) and ataxia-telangiectasia mutated (Atm) knockout mice showed no RAR. Conclusion: The results indicated that PKC, ATM, DNAPK and/or P13K were involved in RAR for growth and BrdU incorporation of cultured glial cells and RAR decreased with ageing. [ABSTRACT FROM AUTHOR]

Describes a three-axis superconducting quantum interference device (SQUID) magnetometer fabricated as a magnetic anomaly detector onboard an aircraft. Magnetometer design; Configuration requirements; Magnetic total field obtained from magnetic vector components.

A case of an aneurysm associated with four coronary artery fistulae originating from three vessels is reported. The patient, a 52-year-old woman, had chest heaviness and palpitations. Coronary arteriography reveaed the four fistulae originating from three coronary vessels with an aneurysm draining into the left ventricle and the main pulmonary artery. The patient's symptoms were relieved after fistulectomy and the aneurysmectomy, suggesting that a coronary steal phenomenon through the fistulae was the cause of her symptoms. This case is of interest because of its rarity, since this is the first case report of an aneurysm associated with four coronary artery fistulae from three vessels. [ABSTRACT FROM PUBLISHER]

A case of an aneurysm associated with four coronary artery fistulae originating from three vessels is reported. The patient, a 52-year-old woman, had chest heaviness and palpitations. Coronary arteriography reveaed the four fistulae originating from three coronary vessels with an aneurysm draining into the left ventricle and the main pulmonary artery. The patient's symptoms were relieved after fistulectomy and the aneurysmectomy, suggesting that a coronary steal phenomenon through the fistulae was the cause of her symptoms. This case is of interest because of its rarity, since this is the first case report of an aneurysm associated with four coronary artery fistulae from three vessels. [ABSTRACT FROM PUBLISHER]

The article describes a case of congenital foregut cyst with dysphagia and stridor in a Thoroughbred foal. The authors mention that the bilocular cyst had an epithelial lining of bronchogenic and esophageal origin. They also explain that concomitant malformation of the laryngeal muscles and cartilage resulted in a combination of anomalies that have not been reported.