17 results on '"Follow-on formula"'
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2. Nutritional safety and suitability of a specific protein hydrolysate derived from a whey protein concentrate and used in an infant formula and follow‐on formula manufactured from hydrolysed protein by FrieslandCampina Nederland B.V.
- Author
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Bohn, Torsten, Castenmiller, Jacqueline, de Henauw, Stefaan, Hirsch‐Ernst, Karen‐Ildico, Knutsen, Helle Katrine, Maciuk, Alexandre, Mangelsdorf, Inge, McArdle, Harry J, Naska, Androniki, Pentieva, Kristina, Siani, Alfonso, Thies, Frank, Tsabouri, Sophia, Vinceti, Marco, Bresson, Jean‐Louis, Castle, Laurence, Fewtrell, Mary, Przyrembel, Hildegard, Dumas, Céline, and Titz, Ariane
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WHEY protein concentrates ,PROTEIN hydrolysates ,INFANT formulas ,INFANT nutrition ,MILK proteins ,MILKFAT ,TOFU ,MILK yield - Abstract
The European Commission asked EFSA to deliver an opinion on the nutritional safety and suitability of a specific protein hydrolysate. It is derived from a whey protein concentrate and used in an infant and follow‐on formula manufactured by FrieslandCampina Nederland B.V., which submitted a dossier to the European Commission to request an amendment of Regulation (EU) 2016/127 with respect to the protein sources that may be used in the manufacture of infant and/or follow‐on formula. The protein hydrolysate under evaluation is sufficiently characterised with respect to the fraction of the hydrolysed protein. In the pertinent intervention study provided, an infant formula manufactured from the protein hydrolysate with a protein content of 2.4 g/100 kcal and consumed as the sole source of nutrition by infants for 3 months led to a growth equivalent to a formula manufactured from intact cow's milk protein with a protein content of 2.1 g/100 kcal. Data on gastrointestinal tolerance of the formula did not raise any concerns. No experimental data have been provided on the nutritional safety and suitability of this protein source in follow‐on formula. Given that it is consumed with complementary foods and the protein source is nutritionally safe and suitable in an infant formula that is the sole source of nutrition of infants, the Panel considers that the protein hydrolysate is also a nutritionally safe and suitable protein source for use in follow‐on formula. The Panel concludes that the protein hydrolysate under evaluation is a nutritionally safe and suitable protein source for use in infant and follow‐on formula, as long as the formula in which it is used contains a minimum of 2.4 g/100 kcal protein and complies with the compositional criteria of Regulation (EU) 2016/127 and the amino acid pattern in its Annex IIIA. [ABSTRACT FROM AUTHOR]
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- 2023
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3. Effect of Fortified Formula on Growth and Nutritional Status in Young Children: A Systematic Review and Meta-Analysis.
- Author
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Brooker, Paige G., Rebuli, Megan A., Williams, Gemma, and Muhlhausler, Beverly S.
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Previous reviews of the effect of young child formulas on health outcomes in infants and toddlers have been inconclusive. In this study, we undertook a contemporary synthesis of studies investigating the effects of consuming fortified milk beverages (compared to cow's milk or unfortified comparator formula) on growth and/or nutritional status in children 1–3 years of age. Five electronic databases were searched (PubMed, Web of Science, Scopus, ProQuest, and Cochrane Library) for randomised controlled trials comparing fortified milk against control milk in young children (9–48 months), published between January 1990 and June 2022. Outcomes were growth, body composition, biochemical markers, and/or nutritional status. Mean differences (MD) were pooled using random-effects meta-analysis where there were ≥3 studies. The risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool. Nineteen articles (12 studies; n = 4795) met the inclusion criteria. Heterogeneity was substantial, likely attributable to considerable variation in study characteristics. Fortified milk was associated with increased weight gain (MD = 0.14 kg [95% CI 0.06, 021], p = 0.0003) compared with control milk. Subgroup analyses demonstrated increases in weight in lower-income countries, and in studies with intervention periods > 6 months. There were no effects of fortified milks on other anthropometric measures. Haemoglobin (MD = 3.76 g/L [95% CI 0.17, 7.34], p = 0.04) and ferritin (MD = 0.01 nmol/L [95% CI 0.00, 0.02], p = 0.02) concentrations were increased in infants consuming fortified milks. Fortified milk beverages appear to offer a safe and acceptable source of complementary nutrition as a short-term strategy for addressing nutritional deficits and may modestly promote weight gain in vulnerable populations when provided for periods > 6 months. This study was prospectively registered with PROSPERO (CRD42022339920) and funded by the Infant Nutrition Council. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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4. Safety of bovine milk osteopontin as a Novel food pursuant to Regulation (EU) 2015/2283.
- Author
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Turck, Dominique, Castenmiller, Jacqueline, De Henauw, Stefaan, Hirsch‐Ernst, Karen Ildico, Kearney, John, Maciuk, Alexandre, Mangelsdorf, Inge, McArdle, Harry J, Naska, Androniki, Pelaez, Carmen, Pentieva, Kristina, Siani, Alfonso, Thies, Frank, Tsabouri, Sophia, Vinceti, Marco, Cubadda, Francesco, Frenzel, Thomas, Heinonen, Marina, Maradona, Miguel Prieto, and Marchelli, Rosangela
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OSTEOPONTIN ,BOS ,MILK yield ,BREAST milk ,INFANT formulas ,MILK - Abstract
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on bovine milk osteopontin (bmOPN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF concerns OPN derived from bovine whey. The NF is intended to be used at a maximum use level of 151 mg/L, in infant formula (IF), follow‐on formula (FoF) and ready‐to‐eat dairy‐based meals for children up to 35 months of age. As compared to the concentrations naturally present in cow's milk and concentrations found in IF on the market reported in the literature, the proposed use level of the NF represents an about 10‐fold higher concentration of bmOPN. The intended use levels of the NF would provide bmOPN at a concentration within the range of human milk (hm) OPN. In a 6‐month study, 14, 72 and 140 mg bmOPN/L in reconstituted (as consumed) IF were given to 279 infants in order to study possible effects on frequency and severity of adverse events, and growth, formula intake and stool consistency. Despite that a number of inconsistencies and limitations were noted in the study report, the Panel considers that the results obtained from this study do not raise safety concerns. Considering the source of the NF, that neither the toxicological studies nor the provided infant study do raise safety concerns, and the low bmOPN plasma levels in infants resulting from the consumption of the NF, the Panel considers that the margin of exposure (i.e. 36) between the NOAEL of the subchronic toxicity study (1,200 mg/kg bw per day) and the highest P95 estimate for infants (33.4 mg/kg bw per day) is sufficient. The Panel concludes that the NF is safe under the proposed conditions of use. [ABSTRACT FROM AUTHOR]
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- 2022
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5. Article: What is Codex, and Why is it Important?: The Codex Committee on Nutrition and Foods for Special Dietary Uses: Report November 2021.
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Mandell, Lisa and Arendt, Maryse
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The article discusses role of Codex Alimentarius Commission to help families reach their breastfeeding goals. It mentions standard for growing up milk (GUM), identified by Codex as drink or product for young children with added nutrients; and also mentions recommendations for breastfeeding during the COVID 19 pandemic.
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- 2022
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6. Türkiye'deki Bebek ve Devam Formüllerinin Enerji ve Besin Ögeleri İçeriklerinin ve Bazı Etiket Bilgilerinin Değerlendirilmesi.
- Author
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TUNÇER, Esra, BAYINDIR GÜMÜŞ, Aylin, and KESER, Alev
- Abstract
Copyright of Turkiye Klinikleri Journal of Health Sciences / Türkiye Klinikleri Sağlık Bilimleri Dergisi is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
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7. Folgenahrungen für Kleinkinder im Alter von einem bis 3 Jahren (sog. Kindermilchgetränke).
- Author
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Koletzko, B., Bührer, C., Jochum, F., Kauth, T., Körner, A., Mihatsch, W., Prell, C., Reinehr, T., and Zimmer, K.-P.
- Abstract
Copyright of Monatsschrift Kinderheilkunde is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
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8. Scientific Opinion on the safety and suitability for use by infants of follow-on formulae with a protein content of at least 1.6 g/100 kcal.
- Author
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Turck, Dominique, Bresson, Jean‐Louis, Burlingame, Barbara, Dean, Tara, Fairweather‐Tait, Susan, Heinonen, Marina, Hirsch‐Ernst, Karen Ildico, Mangelsdorf, Inge, McArdle, Harry J, Naska, Androniki, Neuhäuser‐Berthold, Monika, Nowicka, Grażyna, Pentieva, Kristina, Sanz, Yolanda, Sjödin, Anders, Stern, Martin, Tomé, Daniel, Van Loveren, Henk, Vinceti, Marco, and Willatts, Peter
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INFANT formulas ,SOY proteins ,MILK proteins - Abstract
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the safety and suitability for use by infants of follow-on formulae (FOF) based on cow's milk intact protein with a protein content of at least 1.6 g/100 kcal (rounded value) that meet otherwise the requirements of relevant EU legislation. If the formula under evaluation is considered to be safe and suitable for use by infants, the NDA Panel is also asked to advise on whether FOF based on goat's milk intact protein, soy protein isolates or protein hydrolysates are also safe and suitable for infants under the same conditions. The Panel concludes that the use of FOF with a protein content of at least 1.6 g/100 kcal from either intact cow's milk protein or intact goat's milk protein otherwise complying with the requirements of relevant EU legislation is safe and suitable for healthy infants living in Europe with an intake of complementary foods of a sufficient quality. This conclusion does not apply to infant formula (IF). The Panel also concludes that the safety and suitability of FOF with a protein content of at least 1.6 g/100 kcal manufactured from either protein hydrolysates or soy protein isolates cannot be established with the available data. The same conclusion applies to IF. The NDA Panel endorsed a draft of this scientific opinion on 14 December 2016 for public consultation. The draft document has been revised and updated according to the comments received, where appropriate. [ABSTRACT FROM AUTHOR]
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- 2017
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9. Scientific Opinion on the essential composition of infant and follow-on formulae.
- Subjects
DIETETICS ,FOOD additives ,DIETARY supplements ,METABOLISM - Abstract
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the essential composition of infant and follow-on formula. This opinion reviews the opinion provided by the Scientific Committee on Food in 2003 on the essential requirements of infant and follow-on formulae in light of more recent evidence and by considering the Panel's opinion of October 2013 on nutrient requirements and dietary intakes of infants and young children in the European Union. The minimum content of a nutrient in formula proposed in this opinion is derived from the intake levels the Panel had considered adequate for the majority of infants in the first six months of life in its previous opinion and an average amount of formula consumed during this period. From a nutritional point of view, the minimum contents of nutrients in infant and follow-on formula proposed by the Panel cover the nutritional needs of virtually all healthy infants born at term and there is no need to exceed these amounts in formulae, as nutrients which are not used or stored have to be excreted and this may put a burden on the infant's metabolism. Therefore, the Panel emphasises that maximum amounts should be interpreted not as target values but rather as upper limits of a range which should not be exceeded. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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10. Outcome of a public consultation on the draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the essential composition of infant and follow‐on formulae.
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DIETETIC foods ,INFANT formulas - Published
- 2014
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11. Iron status of one-year-olds and association with breast milk, cow's milk or formula in late infancy.
- Author
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Thorisdottir, Asa, Ramel, Alfons, Palsson, Gestur, Tomassson, Helgi, and Thorsdottir, Inga
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ANALYSIS of variance ,BREAST milk ,CONFIDENCE intervals ,INFANT formulas ,INFANT nutrition ,IRON ,MILK ,RESEARCH funding ,STATISTICAL sampling ,STATISTICS ,DATA analysis ,DATA analysis software ,DESCRIPTIVE statistics ,CHILDREN - Abstract
Purpose: Studies on iron status in infancy and early childhood have shown contradicting results concerning prolonged breast-feeding and cow's milk intake. The aim of the present study was to investigate associations between iron status among one-year-olds and feeding, with focus on the type of milk. Methods: Randomly selected healthy infants were prospectively investigated until 1 year of age in two cohorts born 1995-1996 ( n = 114) and 2005 ( n = 140). Information on birth data, feeding and growth until 12 months and iron status at 12 months was collected. Data from the two cohorts were pooled and the infants categorized into three groups according to their predominant milk consumption at 9 months of age, that is, breast milk, cow's milk or follow-on formula. Results: The prevalence of iron deficiency was highest in the cow's milk group and lowest in the follow-on formula group. According to a linear model, adjusted for gender, birth weight and exclusive breast-feeding duration, cow's milk consumption was negatively associated with serum ferritin (SF) and formula positively, but breast milk not. Predicted SF (μg/l) = 11.652(intercept) − 5.362(boy) + 0.005 × birth weight (g) + 2.826(exclusively breastfed ≥ 4 months) + 0.027 × formula (ml) − 0.022 × cow's milk (ml) + 0.005 × breast milk (ml). Correction for other dietary factors did not change these results. Conclusion: In this pooled analysis, cow's milk intake in late infancy associated negatively, and follow-on formula positively, with iron status. Prolonged partial breast-feeding does not seem to be of importance for iron status. Fortified food seems to improve iron status in late infancy. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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12. Isolation of Enterococcus from powdered infant and follow-on formulas, and their antibiotic susceptibilites.
- Author
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Kang, Tae-Mi and Park, Jong-Hyun
- Abstract
Enterococcus spp. from powdered infant formula and follow-on formulas were identified and characterized for antibiotic susceptibility to confirm the enterococcal safety. Seventy-three Enterococcus from 96 powdered infant formulas and 26 strains from 33 follow-on formulas were isolated. More than 90% of Enterococcus in the foods were E. faecium. E. casseliflavus, and E. faecalis were also isolated. All Enterococcus were sensitive to ampicillin, penicillin, tetracycline, and vancomycin. However, 2 E. casseliflavus showed low resistance to vacomycin by minimum inhibitory concentration 4.0 μg/mL. Multiplex PCR indicated no existence of highly hazardous vancomycinresistant vanA and vanB genes. The isolates also showed the broad susceptibilities to erythromycin, ripampin, and streptomycin. Major strains of about 60% were intermediately and highly resistant to erythromycin and streptomycin, respectively. However, Enterococcus resistances to those antibiotics were not high and similar to those of Enterococcus from the other evaluated foods. Therefore, it appeared that powdered infant formula and follow-on formula might be safe to Enterococcus with regard to vancomycin and the antibiotics. [ABSTRACT FROM AUTHOR]
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- 2012
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13. Quality and Safety Aspects of Infant Nutrition.
- Author
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Koletzko, Berthold, Shamir, Raanan, and Ashwell, Margaret
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BREASTFEEDING ,FOOD contamination ,INFANT nutrition ,QUALITY assurance ,RESEARCH funding ,SAFETY ,EVALUATION - Abstract
Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition. Unbalanced diets and harmful food components induce particularly high risks for untoward effects in infants because of their rapid growth, high nutrient needs, and their typical dependence on only one or few foods during the first months of life. The concepts, standards and practices that relate to infant food quality and safety were discussed at a scientific workshop organized by the Child Health Foundation and the Early Nutrition Academy jointly with the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, and a summary is provided here. The participants reviewed past and current issues on quality and safety, the role of different stakeholders, and recommendations to avert future issues. It was concluded that a high level of quality and safety is currently achieved, but this is no reason for complacency. The food industry carries the primary responsibility for the safety and suitability of their products, including the quality of composition, raw materials and production processes. Introduction of new or modified products should be preceded by a thorough science based review of suitability and safety by an independent authority. Food safety events should be managed on an international basis. Global collaboration of food producers, food-safety authorities, paediatricians and scientists is needed to efficiently exchange information and to best protect public health. Copyright © 2012 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
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- 2012
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14. Leches de crecimiento en la alimentación infantil.
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Dalmau Serra, J. and M. Moreno Villares, J.
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INFANT weaning ,BREAST milk ,PROTEINS ,BREASTFEEDING ,INFANT nutrition - Abstract
Copyright of Acta Pediátrica Española is the property of Ediciones Mayo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2011
15. Composition of the non-protein nitrogen fraction of goat whole milk powder and goat milk-based infant and follow-on formulae.
- Author
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Prosser, Colin G., McLaren, Robert D., Frost, Deborah, Agnew, Michael, and Lowry, Dianne J.
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INFANT nutrition ,PROTEINS ,NITROGEN excretion ,BREAST milk ,GLUTAMIC acid - Abstract
The non-protein nitrogen fraction of goat whole milk powder and of infant and follow-on formulae made from goat milk was characterized and compared with cow milk powder and formulae. Goat milk infant formula contained 10% non-protein nitrogen, expressed as a proportion of total nitrogen, compared with 7.1% for cow milk formula. Goat follow-on formula contained 9.3% and cow 7.4% non-protein nitrogen. Urea, at 30%, was quantitatively the most abundant component of the non-protein nitrogen fraction of goat milk and formulae, followed by free amino acids at 7%. Taurine, glycine and glutamic acid were the most abundant free amino acids in goat milk powders. Goat milk infant formula contained 4 mg/100 ml total nucleotide monophosphates, all derived from the goat milk itself. Goat milk has a very different profile of the non-protein nitrogen fraction to cow milk, with several constituents such as nucleotides at concentrations approaching those in human breast milk. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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16. Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake.
- Author
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Dobrzyńska, Małgorzata, Drzymała-Czyż, Sławomira, Jakubowski, Karol, Kurek, Szymon, Walkowiak, Jarosław, and Przysławski, Juliusz
- Abstract
The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI) of both micronutrients was estimated. Cu and Zn concentration in 103 formulae for infants, available in the Polish market, were assessed using atomic absorption spectrometry. The estimated DI was calculated from the average energy requirements for the 0–6 months aged infants. The microelement content of formulae was mostly in good agreement with that declared by the manufacturer (5–10% variations compared to the labeled values). The Cu/Zn ratio ranged from 1:8 to 1:25. The estimated DI of Cu was in the range of 0.14–1.11 mg/day. Six (6.7%) of the formulae did not meet the recommended range of Cu intake, especially during the first month of life and in the case of formulae for special medical purposes. The estimated DI of Zn varied from 2.27–11.25 mg/day. In most cases, the concentration of Cu and Zn in infant formulae was within the recommended range. It would be advisable to consider monitoring the DI of Cu and reconsider the Cu content in formulae for infants in proportion to its expected consumption. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
17. Prevention of anaemia in inner city toddlers by an iron supplemented cows' milk formula.
- Author
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Daly, A., MacDonald, A., Aukett, A., Williams, J., Wolf, A., Davidson, J., and Booth, I. W.
- Published
- 1996
- Full Text
- View/download PDF
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