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This paper developed an analytical solution for the problem of exit point evolution on the seepage face in the unconfined aquifer with sloping interface. A theoretical model for the groundwater drawdown problem in a half‐infinite aquifer with a sloping boundary is built in accordance with the linearized one‐dimensional Boussinesq equation and the Neumann boundary condition at the seepage point. The homotopy analysis method is then adopted for solving this dynamic boundary problem. By constructing two continuous deformations, the original problem could be converted into a group of subproblems with the same physical essence and similar mathematical solutions. To compare this analytical solution, a numerical model based on the finite volume method is developed, which employs adaptive grids to settle the dynamic boundary condition. The comparisons show that the analytical solution agrees with the numerical model well. The results are useful for the quantification of various hydrological problems. The methodology applied in this study is referential for other dynamic boundary problems as well. [ABSTRACT FROM AUTHOR]

Background: Kirschner wire fixation remains to be the mainstream treatment modality in unstable or displaced supracondylar humerus fracture in children, with divergent lateral pins being the most preferred due to their sufficient stability and decreased risk of ulnar nerve injury. However, the entry point at which the proximal lateral pin can be inserted to achieve a more proximal exit and maximum divergence has not been reported. This study retrospectively analyzed the characteristics and factors influencing the entry and exit points of the proximal lateral pins. Methods: The study was divided into two stages. In stage one, the entry and exit points of the proximal pins of lateral pinning configuration were analyzed from intra-operative radiographs of children treated for extension-type supracondylar humerus fractures. The coronal and sagittal pin angles formed by the proximal pins were also measured. Using the findings of stage one, we intentionally tried to achieve a more proximal exit with the proximal pins in stage two. Comparisons between groups of patients treated by random and intentional pinnings were done statistically. Results: In the first stage, 47 (29.2%) of the 161 proximal pins exited above the metaphyseal-diaphyseal junction (MDJ) region. Of these, 85.1% entered from lateral and posterior to the ossific nucleus of the capitellum (ONC). The pin angles averaged 58.4° and 90.5° in the coronal and sagittal planes respectively. In the second stage, 47 (65.3%) proximal pins in the intended group exited above the MDJ region, while only 32 (36%) in the random group exited above the MDJ region. Conclusion: While aiming at the upper border of the distal MDJ during pinning, lateral pins can easily achieve a higher, proximal exit above the MDJ if inserted from lateral and posterior to the ONC and parallel to the humeral shaft in the sagittal plane. Higher exit can also be easily achieved in younger patients and patients fixated with smaller diameter pins. [ABSTRACT FROM AUTHOR]

This article reports on a study that was conducted to evaluate value addition in the learning attainments of students in higher education. The subjects in the study were telecommunication engineering students who pursued their programme of study between 2011 and 2013 at the Ghana Technology University College. Using descriptive statistics and regression analysis, the study sought to test the differences between the mean scores of three groups of students who were categorised based on their entry qualifications and final year cumulative weighted averages (CWAs). The first level of analysis was done by comparing the students’ entry qualifications with their CWAs at the end of the programme. The second level of analysis was done by comparing the students’ first year and final year CWAs in the core and general courses domains. The study concluded that the students’ entry qualifications and CWAs could measure value addition. [ABSTRACT FROM AUTHOR]

Within the developing vertebrate spinal cord, motor neuron subtypes are distinguished by the settling positions of their cell bodies, patterns of gene expression, and the paths their axons follow to exit the CNS. The inclusive set of cues required to guide a given motor axon subtype from cell body to target has yet to be identified, in any species. This is attributable, in part, to the unavailability of markers that demarcate the complete trajectory followed by a specific class of spinal motor axons. Most spinal motor neurons extend axons out of the CNS through ventral exit points. In contrast, spinal accessory motor neurons (SACMNs) project dorsally directed axons through lateral exit points (LEPs), and these axons assemble into the spinal accessory nerve (SAN). Here we show that an antibody against BEN/ALCAM/ SC1/DM-GRASP/MuSC selectively labels mouse SACMNs and can be used to trace the pathfinding of SACMN axons. We use this marker, together with a battery of transcription factor-deficient or guidance cue/receptor-deficient mice to identify molecules required for distinct stages of SACMN development. Specifically, we find that Gli2 is required for the initial extension of axons from SACMN cell bodies, and that netrin-1 and its receptor Dcc are required for the proper dorsal migration of these cells and the dorsally directed extension of SACMN axons toward the LEPs. Furthermore, in the absence of the transcription factor Nkx2.9, SACMN axons fail to exit the CNS. Together, these findings suggest molecular mechanisms that are likely to regulate key steps in SACMN development. [ABSTRACT FROM AUTHOR]