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Introduction: Exploring the influencing factors and functioning mechanisms of thriving at work is of practical significance both for teachers and kindergartens. Based on the socially embedded model of thriving at work, this study aimed to examine the association between negative workplace gossip and thriving at work. The mediating role of psychological contract breach and the moderating role of bianzhi were also examined. Methods: A total of 1105 Chinese kindergarten teachers were chosen to complete a questionnaire on negative workplace gossip, psychological contract breach, and thriving at work. Results: The results demonstrated that negative workplace gossip was positively associated with psychological contract breach and negatively associated with thriving at work. In addition, psychological contract breach was negatively associated with thriving at work. According to the mediation model test, psychological contract breach was a mediating factor between negative workplace gossip and thriving at work. The impact of psychological contract breach on thriving at work could be further moderated by bianzhi. Conclusion: This study complements knowledge systems about the influential factors and functional mechanisms of thriving at work. In practical terms, this study offers a fresh and innovative perspective for kindergartens seeking to enhance teachers' thriving at work. [ABSTRACT FROM AUTHOR]

Introduction: In China, the high turnover rates of teachers have become one of the biggest obstacles to the development of rural preschool education. Objective: Based on the social information processing theory and the strength model of selfcontrol, this study examined the relationship between negative workplace gossip and turnover intention and the role of ego depletion and bianzhi in this relationship. Methods: The questionnaire method was applied, and 411 rural preschool teachers in Hubei Province, China, participated in the survey. Results: The correlation results showed that negative workplace gossip was positively correlated with ego depletion, and ego depletion was positively correlated with turnover intention. After controlling for age, negative workplace gossip positively predicted turnover intention. The mediation analysis indicated that ego depletion played a mediating role in the relationship between negative workplace gossip and turnover intention. Moreover, the mediation effect was moderated by bianzhi. Negative workplace gossip had a stronger effect on the ego depletion of teachers without bianzhi than on that of teachers with bianzhi. Conclusion: The current research is the first to clarify that ego depletion mediates the relationship between negative workplace gossip and turnover intention, and the mediation effect is moderated via bianzhi. These findings expand our understanding of the influential factors and formation mechanisms of turnover intention. In practice, this study provides a novel perspective for policymakers and administrators to reduce the turnover intention among rural preschool teachers in China. [ABSTRACT FROM AUTHOR]

Zanthoxylum undulatifolium is an excellent economic tree species with important medical value. This study reports the first complete chloroplast genome sequence of Z. undulatifolium. Its whole chloroplast genome is 158,400 bp in length, including a large single-copy (LSC) region of 85,898 bp, a small single-copy (SSC) region of 17,610 bp, and two inverted repeat (IR) regions of 27,446 bp. The chloroplast genome contains a total of 132 genes, comprising 87 protein-coding genes, 37 tRNA genes, and eight rRNA genes. The overall GC content of the chloroplast genome is 38.46%, with the corresponding values in the LSC, SSC, and IR regions are 36.87%, 33.51%, and 42.55%, respectively. Phylogenetic analysis revealed the sister relationship between Z. undulatifolium and Z. bungeanum. [ABSTRACT FROM AUTHOR]

Cervical cancer is the third leading cause of cancer death among women in less-developed regions. Because of the poor survivorship of patients with advanced disease, finding new biomarkers for prognostic prediction is of great importance. In the current study, mRNA datasets (GSE9750 and GSE63514) were retrieved from Gene Expression Omnibus and was used to identify differentially expressed genes. The underlying molecular mechanisms associated with high-mobility group box 1 protein (HMGB1) were investigated using bioinformatics analysis. Immunohistochemical analysis of HMGB1 was performed on 239 cases of cervical cancer samples to investigate its possible correlation with clinicopathological characteristics and outcomes. A preliminary validation has been made to explore the possible correlation factors with HMGB1 that promotemigration of cervical cancer cells. Bioinformatics analysis showed that adherens junction was significant for both P-value and enrichment scores, which was consistent with the clinical study. The underlying molecular mechanisms might be the interaction among HMGB1, RAC1, and CDC42. HMGB1 expression was significantly associated with tumor size, parametrial infiltration, the depth of cervical stromal invasion, and FIGO stage (P=0.003, 0.019, 0.013, and 0.003, respectively). FIGO stage, lymph mode metastasis, and HMGB1 expression were independent predictors of a poorer prognosis of patients with cervical cancer. Knockdown of HMGB1 inhibits migration of Siha and C33A cells in vitro. Western blot and quantitative real-time PCR (qRT-PCR) showed that the expression of RAC1 and CDC42 was positively correlated with HMGB1. HMGB1 is a useful prognostic indicator and a potential biomarker of cervical cancer. RAC1 and CDC42 may be involved in the progression of cervical cancer migration induced by HMGB1. [ABSTRACT FROM AUTHOR]

Acremoniumterricola milleretal mycelium (AMM) exerts numerous protective effects on organs, and has been used in Chinese herb prescriptions to treat refractory diseases. The aim of this study was to investigate the effects of AMM on immunological hepatic fibrosis induced by porcine serum (PS) in rats. Male Sprague Dawley rats were administered 0.5 ml sterile PS by intraperitoneal injections twice a week for 18 weeks. AMM (175, 350 or 700 mg/kg) and colchicine (0.1 mg/kg) were administered intragastrically each day until the rats were sacrificed. PS administration resulted in marked hepatic fibrosis, as assessed by increased oxidative stress and hepatic collagen content, as well as a-smooth muscle actin (a-SMA) expression. AMM significantly reduced liver damage and fibrosis. In addition, AMM decreased the elevation in hydroxyproline, hyaluronic acid, laminin and procollagen type III; increased the activity of superoxide dismutase and glutathione peroxidase; decreased a-SMA expression; and eliminated hepatic collagen deposits. Furthermore, AMM inhibited Smad2/3 phosphorylation and Smad7 expression. These results indicate that AMM is able to reduce oxidative stress, inhibit collagen synthesis and block the transforming growth factor-β/Smad signaling pathway in a dose-dependent manner. [ABSTRACT FROM AUTHOR]

Optimal sensor placement is an important part in the structural health monitoring of bridge structures. However, some defects are present in the existing methods, such as the focus on a single optimal index, the selection of modal order and sensor number based on experience, and the long computation time. A hybrid optimization strategy named MSE-AGA is proposed in this study to address these problems. The approach firstly selects modal order using modal participation factor. Then, the modal strain energy method is adopted to conduct the initial sensor placement. Finally, the adaptive genetic algorithm (AGA) is utilized to determine the optimal number and locations of the sensors, which uses the root mean square of off-diagonal elements in the modal assurance criterion matrix as the fitness function. A case study of sensor placement on a numerically simulated bridge structure is provided to verify the effectiveness of the MSE-AGA strategy, and the AGA method without initial placement is used as a contrast experiment. A comparison of these strategies shows that the optimal results obtained by the MSE-AGA method have a high modal strain energy index, a short computation time, and small off-diagonal elements in the modal assurance criterion matrix. [ABSTRACT FROM AUTHOR]

Meiosis and mitosis of six Chinese Actinidiaceae were studied:Saurauia tristylaDC.,S. miniataC. F. Liang&Y. S. Wang,Actinidia chinensisPlach.,A. deliciosa(Cheval.) C. F. Liang&A. R. Ferguson,A. indochinensisMerr. andClematoclethra lasiocladaMaxim. The chromosome numbers ofSaurauia tristylaandS. miniatawere 2n = 6x = 78, establishing a base chromosome number ofx = 13 in the genus, differing from the previous report ofx = 15. The chromosome number ofClematoclethrawas first reported to be 2n = 4x = 48 (x = 12), while that ofActinidiawasx = 29, consistent with previous reports. The base chromosome number ofClematoclethra(x = 12) was derived from an aneuploid decrease fromSaurauia(x = 13).Actinidia (x = 29) was derived from the palaeotetraploid (x = 14), which was formed through the increase of the basic chromosome numberx = 13 tox = 14 by aneuploidy and through the breakage of a centromere to add one more new chromosome. The chromosome data inActinidiawere consistent with the geographical and morphological evidence for the evolution of the three genera. The tropical American and Asian disjunct distribution pattern and the diversity of base chromosome numbers ofSaurauiafurther support the probability that the genus was an early divergent from a common ancestor ofActinidiaandClematoclethra. © 2005 The Linnean Society of London,Botanical Journal of the Linnean Society, 2005,147, 369–374. [ABSTRACT FROM AUTHOR]

The kinetics for complete iron release showing biphasic behavior from pig spleen ferritin-Fe (PSFF) was measured by spectrophotometry. The native core within the PSFF shell consisted of 1682 hydroxide Fe3+ and 13 phosphate molecules. Inhibition kinetics for complete iron release was measure by differential spectrophotometry in the presence of phosphate; the process was clearly divided into two phases involving a first-order reaction at an increasing rate of 46.5 Fe3+/PSFF/min on the surface of the iron core and a zero-order reaction at a decreasing rate of 6.67 Fe3+/PSFF/min inside the core. The kinetic equation [ C(PSFF-Fe3+)max − C(PSFF-Fe3+) t]1/2 = Tmax − Tt gives the transition time between the two rates and represents the complex kinetic characteristics. The rate was directly accelerated twofold by a mixed reducer of dithionite and ascorbic acid. These results suggest that the channel of the PSFF shell may carry out multiple functions for iron metabolism and storage and that the phosphate strongly affects the rate of iron release. [ABSTRACT FROM AUTHOR]