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Copyright of Revista de Cirugia is the property of Sociedad de Cirujanos de Chile and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Cirugia is the property of Sociedad de Cirujanos de Chile and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A highly enantioselective copper-catalyzed alkynylation of quinolinium salts is reported. The reaction employs StackPhos, a newly developed imidazole-based chiral biaryl PN ligand, and copper bromide to effect a three-component reaction between a quinoline, a terminal alkyne, and ethyl chloroformate. Under the reaction conditions, the desired products are delivered in high yields with ee values of up to 98 %. The transformation tolerates a wide range of functional groups with respect to both the alkyne and the quinoline starting materials and the products are easily transformed into useful synthons. Efficient, enantioselective syntheses of the tetrahydroquinoline alkaloids (+)-galipinine, (+)-angustureine, and (-)-cuspareine are reported. [ABSTRACT FROM AUTHOR]

A highly enantioselective copper-catalyzed alkynylation of quinolinium salts is reported. The reaction employs StackPhos, a newly developed imidazole-based chiral biaryl P,N ligand, and copper bromide to effect a three-component reaction between a quinoline, a terminal alkyne, and ethyl chloroformate. Under the reaction conditions, the desired products are delivered in high yields with ee values of up to 98%. The transformation tolerates a wide range of functional groups with respect to both the alkyne and the quinoline starting materials and the products are easily transformed into useful synthons. Efficient, enantioselective syntheses of the tetrahydroquinoline alkaloids (+)-galipinine, (+)-angustureine, and (-)-cuspareine are reported. [ABSTRACT FROM AUTHOR]

Betsi Cadwalader University Health Board collaborated with the Welsh government and Innovate UK to launch through the Small Business Research Initiative to find innovative solutions for the North Wales Brain Injury Service. The focus was to develop new technology that can make a difference for service users and rehabilitation staff. Acquired brain injury often causes difficulties with executive functions and memory, which compromises the service user's ability to carry out instrumental activities of daily living, such as cooking (Tanguay et al., 2014). Thus the initiative was to develop an app that would support service users' continuance of independent and efficient meal preparation. Having secured funding, SymlCONNECT, in collaboration with the occupational therapy department at Glyndwr University, is currently developing and trialling MASCOT, a rehabilitation support app. With an increasing number of people using mobile technology, the use of apps to support interventions becomes a more viable aid to incorporate into daily tasks (El-Gayar et al., 2013). This app is a structured stage-by-stage, multi-media breakdown of various recipes that are graded according to difficulty. The app's content and presentation can be easily customised by the therapist and guides the service user stage by stage, highlighting key tasks and areas of safety. There is a selfrating facility upon completion of each recipe, but also accessible as 'help' throughout which is digitally mirrored on the therapist terminal and can be discussed and content altered accordingly. This technology offers the potential to engage the service user in self-management techniques, to facilitate cognition and more importantly independence. [ABSTRACT FROM AUTHOR]