1. Unique Isospora -associated histologic lesions in white-rumped shama (Copsychus malabaricus).
- Author
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Wong, Talia S., Stalis, Ilse H., Witte, Carmel, and Kubiski, Steven V.
- Subjects
GASTROINTESTINAL system ,BONE marrow ,INFLAMMATION ,PASSERIFORMES ,SPLEEN ,CONNECTIVE tissues - Abstract
Twenty-one white-rumped shamas (19 necropsied, 2 biopsied) (Copsychus malabaricus) housed at the San Diego Zoo between 1992 and 2020 were diagnosed with Isospora infection based on evaluation of histologic sections. Review of these cases revealed a consistent histologic lesion characterized by nodular aggregates of atypical epithelioid macrophages containing few intracytoplasmic protozoa, with or without lymphocytic infiltrates. Of the 19 necropsied cases, 16 (84%) had systemic lesions variably affecting the liver, spleen, gastrointestinal tract, lung, pancreas, connective tissues, or bone marrow, while all 21 diagnosed cases had skin involvement. The findings suggest that white-rumped shamas have a unique inflammatory response to isosporosis with a predilection for the skin. Skin may be a diagnostically sensitive sampling site for histologic diagnosis of Isospora in this species. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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