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Background: Insomnia is commonly reported in patients with asthma. However, the prevalence of insomnia and its relationship to asthma control have not been established. Objective: To determine the prevalence of insomnia in adults with asthma and to evaluate the association between insomnia and level of asthma control. Methods: This is a cross-sectional study of 200 patients recruited from pulmonary clinics at a tertiary care center. Adults (age ≥ 16 years) diagnosed with asthma by the primary treating physician were recruited over a 6-month period from December 2018 to May 2019. Asthma and insomnia severity were assessed using the Asthma Control Test and Insomnia Severity Index (ISI). Results: The mean age of participants was 51± 17 years, and 67% were female. Insomnia (ISI score ≥ 10) was present in 46.5% of the participants. The severity of insomnia was inversely related to the level of asthma control: moderate-to-severe insomnia was more frequent in patients with uncontrolled asthma (43%) than in those with partially controlled asthma (25%) or well-controlled asthma (12%) (P < 0.05 for all comparisons). Conclusion: Insomnia is common among patients with asthma, especially those with suboptimal asthma control. Further investigations are required to more fully understand the complex relationship between asthma and insomnia. [ABSTRACT FROM AUTHOR]

Sleep disturbances are commonly reported by patients with asthma. However, the prevalence of sleep disturbance and its association with the level of asthma control is unknown. The primary objective was to determine the prevalence of sleep disturbance among Saudi adult asthmatic patients attending pulmonary clinics at King Abdulaziz Medical City (KAMC). The study also aimed to compare sleep quality between controlled and uncontrolled asthma patients. The study was carried out in the outpatient pulmonary clinics at KAMC and utilized a cross-sectional survey. The survey included five different questionnaires: asthma control test and questionnaires related to the quality of sleep (Pittsburgh sleep quality index [PSQI], Epworth sleepiness scale [ESS], Berlin questionnaire [a measure of obstructive sleep apnea risk], and insomnia severity index [ISI]). Among the 200 asthma patients, 66% suffered from poor sleep quality (PSQI > 5), 43% were at high risk for obstructive sleep apnea, 25% had excessive daytime sleepiness (ESS > 10), and 46.5% had significant clinical insomnia (ISI ≥ 10). Poor sleep quality was less common in patients with well-controlled asthma (37%) compared to those with partially controlled asthma (78%) and uncontrolled asthma (82%) (p < 0.001). Poor sleep quality was common among patients with asthma, particularly those with suboptimal levels of asthma control. Further studies are needed to better understand the interaction between these two conditions. [ABSTRACT FROM AUTHOR]

Background: Carbon monoxide poisoning (COP) represents a significant burden and potential cause of death. However, there are only a few studies about COP in Saudi Arabia despite its noticeable impact on the community. Objective: This systematic review aimed to estimate the prevalence of COP at the level of Middle Eastern and North African region based on WHO distribution, with a particular interest to extrapolate the case fatality rate (CFR) and complications rates among COP victims. Methods: By reviewing the databases (Cochrane Library, Pubmed, EMBASE, and CINAHL) in a strategic approach, the relevant studies were retrieved and reviewed independently. Studies were included based on a predefined set of criteria. The quality of each study was evaluated by the Newcastle-Ottawa Scale (NOS). Outcome measures included the incidence (the primary outcome), gender, age, mortality and complications rate, seasonal variations, geographical area, source, and mechanism of exposure. Results: From 2489 citations, only thirteen studies met the eligibility criteria from five different countries. The date of publication of included studies ranged from 2000 to 2017. The mean sample size was 1483 victims. Most of the victims were females (64.24%). The mean age of the victims was 29.6 years old. The overall incidence of COP was estimated to be equal to 13.37 per 100,000 inhabitants per year. Most of the COP events happened in the winter. Gas heaters were the most frequent source. Conclusion: COP is still a significant burden though it is potentially preventable. Policies and obligations need reevaluation, and public awareness should be raised. [ABSTRACT FROM AUTHOR]