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Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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骨质疏松症是一种以骨量减少和骨组织微结构破坏,导致骨脆性增加和骨折危险性增加为特点的全身性 疾病。全球范围内,骨质疏松症女性患病率高于男性,且近年来随着年龄的增加患病率大幅上涨。各国骨质疏松症 的患病率均处于较高水平,与环境、生活习惯或种族的差异等有关。在不同地区、不同民族,我国骨质疏松症的患病 率有较大差异。在骨质疏松症的管理中,多数国家建议对人群进行骨折危险因素评估,再根据结果考虑是否进行骨 密度测量和骨折风险评估,确定防治方案。针对骨质疏松症的防治,既要加强患病人群的筛选和管理,也要倡导防 治并重及个体化治疗。未患病或低风险者需要保持健康的生活方式,而中高风险者需根据自身情况,在医生指导下 选择合适的治疗方案和药物,同时通过健康的生活方式防止或延缓骨量的降低,目前常用的药物有骨吸收抑制剂和 骨形成促进剂,包括双膦酸盐类、雌激素、降钙素､RANKL抑制剂、甲状旁腺激素类似物等。 关键词:骨质疏松症;骨质疏松症并发症;骨折;骨吸收抑制剂;骨形成促进剂;双膦酸盐类药物;雌激素 [ABSTRACT FROM AUTHOR]

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