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Immigrants need to constantly manage their legal status while straddling uncertain life circumstances and shifting policies. U.S. immigrant policies treat immigrants based on U.S. internal and international political needs. This practice is only further heightened during a global crisis such as the recent COVID‐19 pandemic. Immigrants' existing citizenship contributes to the constraints they experience. Using Chinese international students studying in graduate programs as an example, this paper studies the dual liminality highly skilled immigrants experience in sustaining their legal status and developing their careers. Adopting a life course perspective, this paper reveals that liminal legality constrains immigrants' career choices as they transition from students to full‐time professionals. Acquiring legal status takes precedence over their career goals. They may forfeit career opportunities to secure legal status. Moreover, their Chinese citizenship hinders their career advancement. In recent years, United States–China rivalry in international politics and intellectual competition has intensified. Combined with a racialized construction of U.S. citizenship, highly skilled Chinese immigrants experience a heightened sense of vulnerability vis‐a‐vis institutional scrutiny and mistreatment. [ABSTRACT FROM AUTHOR]

This paper conducted a comparative analysis of the conference publications published by Chinese scholars from 2006 to 2019. The main results are as follows. First, the conference papers are unevenly distributed among the 31 provincial administrative regions. The annual number of conference papers published by scholars from different regions fluctuated during the study period. Second, there are different disciplinary distributions of China Proceedings of Conferences Full‐text Database (CPCD) papers and Conference Proceedings Citation Index (CPCI) papers, and the CPCI publications have a relatively centralized disciplinary distribution. Third, it is noteworthy that there are more CPCD papers than CPCI papers. With the introduction of the new science and technology evaluation standards of the Ministry of Science and Technology, there should be more conference papers in the future. [ABSTRACT FROM AUTHOR]

One of the most dramatic changes in global publishing in the last decade has been the emergence of China. China now has more researchers than the United States, outspends the United States and European Union in research and publishes more scientific papers each year than any other nation in the world. The quality of these papers is also increasing, with more appearing in top‐ranked journals and gaining more citations overall. Despite this success, China has gained an unenviable reputation for research misconduct and geopolitical issues threaten its continuation. Given the impact of China's growing presence on editors, publishers and non‐Chinese authors seeking to publish in the same journals, it is important to understand the reasons, directions and outcomes of these changes, their effect on Chinese scholars and local Chinese journals, and where they might be leading. In this review paper I explore the rise of Chinese scholarship, its influence on global publishing and on Chinese scholars, and how the Chinese government is responding to its new role in global academic publishing. [ABSTRACT FROM AUTHOR]

Metaverse is an emergent technology that facilitates consumer interaction and participation in various activities within an integrated virtual environment. Considering the Metaverse's swift growth, comprehension of the perspectives and inclinations of its prospective users is critical. Considering configuration and complexity theories, this article examines the causal patterns of factors and fragmented perspectives concerning using Metaverse applications (M‐apps). It does so by examining how functional (ease of use, privacy), social (interactivity, presence), and personality (locus of control, openness to experience) factors combine as causal configurations to describe consumer adoption (MTA). Hence, fuzzy‐set qualitative comparative analysis is employed to empirically examine the proposed configurational model by analyzing a sample of 372 Chinese consumers of different M‐Apps. The notable MTA was determined to be explained under four distinct solutions with varying configurations of function, social, and personality in various combinations. The findings of this paper's complexity analysis constitute a scholarly and practical contribution to consumer acceptance of M‐apps, allowing for the customization of Metaverse functionality to meet every consumer's needs. [ABSTRACT FROM AUTHOR]

This paper investigates the connections between harmonious cultural values, pro‐environmental self‐identity and consumers' sustainable consumption behaviours spanning acquisition, usage and disposal. It evaluates the relevance of Chinese cultural values that purport harmony between humans, nature and society that is, man‐nature orientation, and horizontal/vertical dimensions of individualism collectivism. The results from the online survey with 503 urbanised Chinese reveals these values disparately influence this consumption. Despite the limited direct behavioural effect of these harmonious values, pro‐environmental self‐identity plays an important role in mediating their indirect effects on the five behaviours. This paper therefore extends theorisation of the values‐identity‐behaviour relationship from a cultural‐values orientation perspective. It offers new insights to understand urbanised Chinese consumers sustainable consumption behaviours. [ABSTRACT FROM AUTHOR]

Brentuximab vedotin (BV) has been approved for CD30‐positive cutaneous T‐cell lymphoma (CTCL) after at least one previous systemic treatment in China. However, real clinical practice is still limited. We aim to retrospectively review our experience with BV in a cohort of Chinese patients with CTCL, focusing on its efficacy and safety. We included 17 CTCL patients treated with BV at Peking Union Medical College Hospital from January 2021 to June 2024, including 12 with mycosis fungoides (MF)/Sézary syndrome (SS) and five with primary cutaneous anaplastic large‐cell lymphoma (pc‐ALCL). Patients had previously received a median of three treatment regimens (including acitretin, interferon, methotrexate, histone deacetylase inhibitors, phototherapy, radiotherapy, and chemotherapy). Sixteen patients received BV treatment at an initial dose of 1.8 mg/kg intravenously every 3 weeks, either as monotherapy (7/17) or in combination with gemcitabine, chidamide, or multiagent chemotherapy. The median treatment cycle has six cycles. Two patients received BV as the last treatment before undergoing allogeneic stem cell transplantation (alloSCT). The overall response rate (ORR) was 71% (13/17), with 18% (3/17) achieving complete remission (CR). In the MF/SS group, the ORR was 58% (7/12), while in the pc‐ALCL group, it was 100% (5/5). Adverse events (AEs) were observed in 12 patients, including peripheral neuropathy (PN) in three cases, fever in six cases, neutropenia in three cases, exfoliative dermatitis in two cases, and abnormal liver function in one case. Only one patient experienced ≥ Grade 3 AEs. Based on clinical experience in our center, BV, either as monotherapy or combined with chemotherapy, showed a good response in the treatment of advanced CTCL patients with good tolerability. [ABSTRACT FROM AUTHOR]

Objectives: The ALINE trial demonstrated the superiority of alectinib over platinum‐based chemotherapy in resected Anaplastic Lymphoma Kinase (ALK)‐positive non‐small‐cell lung cancer (NSCLC). Considering the high cost of alectinib, this study aimed to evaluate the economic value of alectinib compared to platinum‐based chemotherapy for treating early‐stage ALK‐positive NSCLC from the perspective of the Chinese health care system. Materials and Methods: We developed a five‐state Markov model with monthly cycles to estimate the lifetime costs, life‐years (LYs), quality‐adjusted life‐years (QALYs), and incremental cost‐effectiveness ratios (ICERs) in terms of cost per LY gained and per QALY gained. Costs were obtained from database, expert opinions and published literature, and utilities were primarily derived from a multicenter cross‐sectional study based on the Chinese population. Costs and outcomes were discounted at 5% per year. Sensitivity analyses and scenario analyses were conducted to assess uncertainty in model results. Results: Compared to platinum‐based chemotherapy, alectinib increased total costs by $16,245 and provided gains of 2.02 LYs and 1.84 QALYs over a lifetime horizon. ICERs were $8,052/LY and $8,806/QALY. The ICER in terms of cost per QALY gained was most sensitive to the outcome discount rate. Probabilistic sensitivity analysis indicated a 93% probability of alectinib being cost‐effective at a willing‐to pay (WTP) threshold of $12,367/QALY (1 GDP per capita), rising to 100% at $37,100/QALY (3 GDP per capita). Conclusion: Alectinib appears to be the preferred cost‐effective option in the adjuvant treatment for Chinese patients with resected early‐stage ALK‐positive NSCLC. [ABSTRACT FROM AUTHOR]

Background: Circulating tumor DNA (ctDNA) has emerged as a promising biomarker for noninvasive cancer diagnostics, particularly in the context of metastatic non‐small‐cell lung cancer (NSCLC). Detecting targetable variants through ctDNA analysis offers the potential to guide treatment decisions, especially in cases where tissue samples are insufficient or unavailable. Method: In this study, we developed and validated a next‐generation sequencing panel targeting 101 cancer‐related genes (101‐test) to detect somatic variants in ctDNA from a large cohort of Chinese patients with metastatic NSCLC. The performance of the 101‐test was assessed by evaluating its limit of detection (LOD), accuracy, and precision in identifying molecular variants. Additionally, the concordance between ctDNA and tissue samples for detecting targetable variants was analyzed in 904 patients. Results: The 101‐test demonstrated a LOD of 0.38% for single‐nucleotide variants (SNVs), 0.33% for insertions and deletions (InDels), and 0.33% for fusions. Sensitivity was 98.3% for SNVs, 100% for InDels, and 100% for fusions when compared to digital droplet PCR (ddPCR)/breakpoint PCR reference methods. The by‐variant sensitivity for somatic variants was 97.5%, with a specificity of 99.9% between tumor‐only and tumor‐normal analyses. In a real‐world cohort, the concordance between ctDNA and tissue samples for identifying targetable variants was 72.2% (457/633). Notably, the EGFR S768I variant, recently recommended by clinical guidelines, achieved an 80% concordance rate. Furthermore, 4.3% of patients (27/633) with targetable variants were identified exclusively through ctDNA testing. Conclusion: The ctDNA‐based 101‐test is a highly sensitive and specific tool for detecting targetable variants in metastatic NSCLC, particularly in cases with insufficient tissue samples. The findings support the use of ctDNA testing as a reliable and complementary method to traditional tissue‐based molecular analysis, enhancing the precision of treatment strategies for NSCLC patients. [ABSTRACT FROM AUTHOR]

The retranslations of Andersen's fairy tales in the twentieth century have promoted the canonization of Andersen in the modern Chinese literary system. Today, Chinese readers of different ages are fascinated by Andersen's works and the images created by him. However, the literary and cultural significance of Andersen to China lies in his influence. In this paper, the authors will first review the history of translating Andersen's fairy tales in China and then analyze some cases from Chinese literature and culture within the theoretical framework of intertextuality, in an attempt to specify the influence of Andersen on modern Chinese literature and culture. It is argued that Andersen's fairy tales have been cross‐culturally woven into Chinese children's as well as adult literature when the intertextual devices are applied by writers in their own literary creations; meanwhile the fictional elements of the tales are intertextually merged, as symbols, into other forms of cultural products where they are involved in a critical construction of modern Chinese culture. [ABSTRACT FROM AUTHOR]

China's per capita dairy consumption has been far below the intake level recommended by the World Health Organization. Since the dairy industry is a significant contributor to carbon emissions, the recently launched "Double‐Carbon" goals in China may also suppress the supply of dairy products, further reducing Chinese residents' dairy intake. While the notion of sustainable (i.e., nutritious and environmentally friendly) food consumption has recently gained popularity in the policy arena, whether Chinese milk consumers are ready to embrace this notion and what specific measures can effectively promote sustainable milk consumption in China remain unclear. On the basis of a discrete choice experiment, this paper examines how information nudges (i.e., randomly provided messages with different contents and details) may steer Chinese consumers into choosing liquid milk products with attributes that are more nutritious and environmentally friendly. Our analysis, involving 839 consumers randomly selected from Beijing, China, shows that consumers value carbon labels the most, followed by nutrition claims, sustainable production claims, and energy conservation certificates. Meanwhile, nutrition information induces consumers to place higher values on nutrition claims; in contrast, environmental information raises consumers' willingness to choose environmental sustainability‐related attributes. Finally, the concreteness of the information provided strengthens these effects [EconLit Citations: D12, Q01, Q13, Q18]. [ABSTRACT FROM AUTHOR]

This document provides summaries of various research studies on depression. The studies cover a range of topics, including the impact of trauma reporting on journalists, stigma and self-stigma of mental illness in Turkey, the relationship between depression severity and perceived cognitive impairment, the construct validity of a depression scale in Chinese adolescents, the interaction between a specific gene and peer rejection in predicting depression among Chinese adolescents, a clinical psychoinformatics approach to detect signs of depression recurrence, the prevalence of depression, anxiety, and stress among Filipino university students, the influencing factors of depression among 11th grade students in China, the effectiveness of a Mindful Self-Compassion program on college students with depression, and the effectiveness of a self-help paper-based Acceptance and Commitment Therapy intervention in reducing the risk of depression. The studies provide valuable insights into the causes, effects, and treatment of depression, highlighting the need for intervention and mental health support. [Extracted from the article]

Using China's milk scandal as a natural experiment, this paper explores whether the countries of origin and export destinations have the same responses to the original country's food scandal. Our difference‐in‐difference estimation shows that the outbreak of China's milk scandal had asymmetric impacts on China's total imports (increased by 23.4%) and exports (sharply dropped by 65.8%). The results further show that China's milk scandal contributed to import increases from European and Oceanian countries. Moreover, China's milk scandal worsened exports, mainly those going to neighbouring Asian regions but increased exports to Oceania. A product quality index is constructed to explain this finding. Intuitively, consumers' perceived quality of Chinese products declined, and they tended to consume products from other countries. The lower the product quality was with those in China, the lower the perceived quality and safety, thereby affecting demand. During the scandal, Chinese consumers tended to buy high‐quality dairy products from Europe and Oceania rather than the perceived unreliable dairy products produced by China or neighbouring countries. We conclude that product quality plays a key role in imports and exports when facing food scandals. [ABSTRACT FROM AUTHOR]

Nationalism is often associated with xenophobia and isolationism in academic literature. The negative image of nationalism has been further strengthened by the electoral success of far‐right political figures across the world. However, treating all nationalism as a uniformly negative phenomenon risks over‐simplification, as nationalism might manifest differently given different social context and rhetorical resources available. Taking Hong Kong as a case, this paper theorises Hong Kong as a stateless nation and examines the alleged negative association of nationalism. It moves beyond the traditional 'Hong Kong vis‐a‐vis China' framework and explores the relationship between Hong Kong nationalists and non‐Chinese international actors. Drawing on data from major Hong Kong political parties' Facebook page, this paper shows that Hong Kong nationalism exhibits a high level of internationalism in both inward and outward dimensions, theorised, respectively, as the willingness to accept foreign influence and to invite international cooperation, and therefore offers a nuanced understanding about the relationship between nationalism, xenophobia and isolationism. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Analytical Psychology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The present study examined the influence of lay elitism on preference and choice inconsistency in consumer choices across cultures. Four studies were conducted to understand this phenomenon. In Study 1, we showed that Mainland Chinese high in the belief in lay elitism displays more preference and choice inconsistency across product categories. In Study 2, we found the reverse effect for Caucasian Americans. In Study 3, Mainland Chinese belief in lay elitism is associated with their preference and choice inconsistency over geometric patterns and, at the same time, increased the consistency between their choice and the anticipated elites' choice of these geometric patterns. Lastly, Study 4 showed that in a cross‐cultural study, Mainland Chinese participants' endorsement of lay elitism is associated with a higher level of preference and choice inconsistency, but the reverse pattern is observed for Caucasian Americans. Furthermore, cultural values (i.e., individualism and collectivism) fail to explain the differences in preference and choice consistency across cultures. The paper offers a new perspective in using lay elitism across cultures to understand preference and choice inconsistency in consumer behavior. [ABSTRACT FROM AUTHOR]

Copyright of Canadian Journal of Agricultural Economics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: The goal of the paper is to discover the dynamic features of rural men's age at first marriage, and to explore impacts of marriage expenses on men's age at first marriage in rural China amid a rapid urbanization and sociodemographic transition. Background: Given the rapid urbanization and sociodemographic transition, changes in rural men's marriage timing and its influencing mechanism in China are emerging but remain under examined. Method: The data were collected by the New Urbanization and Sustainable Development research group from Xi'an Jiaotong University in 2018 (n = 1,391). Regression models were used to explore the influence of men's marriage expenses and regional economic factors on their age at first marriage. Results: The relationship between squared total marriage expenses of rural migrant men and their age at first marriage shows as a U‐shaped curve. Conjugal matching, family, premarital migration, and regional economy play important roles for rural men entering their first marriages. Conclusion: Compared with the age‐appropriate married men, the early and late married men tend to have higher marriage expenses. Men with more economic resources are capable of seizing high‐qualified women at a younger age, whereas men with less economic resources need to pay more for their first marriage at an older age. Fathers' lower social class and regional economy significantly delay men's age at first marriage. Implications: This study reveals marriage expense is another important factor influencing men's first marriage entry in rural China and provides a clue to solve difficulties of rural men getting married, especially in societies with ongoing rapid urbanization and sociodemographic transition. [ABSTRACT FROM AUTHOR]

Employees' social media use in the workplace has become a common phenomenon. Thriving at work is a positive psychological state, and conventional wisdom and preliminary research on thriving at work indicate the benefits of thriving for both employees and organizations. However, few studies have linked social media use and employees' sense of thriving. Based on the socially embedded model of thriving at work, this paper explores the relationship between social media use and thriving at work, as well as the mediating role of knowledge sharing and the moderating role of locus of control. Mplus is used to analyze the data of 397 Chinese employees collected at two time points; the results show a significant positive impact of social‐related social media use on thriving at work. However, work‐related social media use was found to have no effect on thriving at work, though knowledge sharing mediates the relationship between social media use and thriving at work. In addition, locus of control moderates the relationship between work‐related social media use and thriving at work. [ABSTRACT FROM AUTHOR]

Background: McLeod syndrome (MLS) and chorea‐acanthocytosis (ChAc) are exceedingly rare diseases characterized by a variety of movement disorders including chorea, dystonia, and Parkinsonism. Genetic analysis plays a key role in early and accurate diagnosis, but relevant variants are still under investigation. This study aims to explore new pathogenic variants in Chinese patients with MLS and ChAc and to conduct a comprehensive analysis of the clinical heterogeneity among these patients. Methods: Eighteen Chinese patients who presented with choreatic movements with negative HTT genetic testing were identified and underwent targeted next‐generation sequencing, verified by Sanger sequencing. Results: Two novel XK variants (c.970A>T, c.422_423del) were identified in three index MLS patients and six novel VPS13A variants (c.9219C>A, c.3467T>A, c.4208dup, c.9243_9246del, c.5364del, c.556‐290_697‐483del) in five index ChAc patients. One copy number variant of VPS13A (g.79827595_79828762del/c.556‐290_697‐483del) was firstly described in Chinese population. Conclusion: As the currently largest descriptive study of MLS and ChAc patients in China, this study expands on the clinical and genetic spectrum of XK and VPS13A, contributing to the clinical diagnosis of MLS and ChAc. [ABSTRACT FROM AUTHOR]

Minimal hepatic encephalopathy (MHE) has a substantial impact on the clinical outcomes and quality of life (QOL) of patients with cirrhosis. However, timely diagnosis and intervention are challenging due to sophisticated diagnostic methods. In this study, 673 healthy controls and 905 patients with cirrhosis were screened, and 660 healthy controls and 757 patients with cirrhosis, divided into the test (292 patients) and validation (465 patients) cohort, were analyzed after screening. A diagnostic model of the Stroop test (Stroop‐CN) was constructed by multivariate linear regression based on the results of healthy controls. The prevalence of MHE and the comparison results with psychometric hepatic encephalopathy score through the Stroop‐CN model were stable in the test and validation cohorts. Moreover, the prevalence of MHE remained significantly higher in patients with worse disease conditions marked as high Child–Pugh grades and the Model for End‐stage Liver Disease and Sodium (MELD‐Na) scores in the test and validation cohort. The EuroQol 5‐D questionnaire revealed that patients with MHE had a worse QOL than those without MHE both in the test and validation cohort. In conclusion, an easy and practical Stroop‐CN model for MHE diagnosis based on the EncephalApp is established. It is found that a considerable number of Chinese patients with cirrhosis experience MHE, which significantly impacts their QOL. [ABSTRACT FROM AUTHOR]

Background: Skin "yellowness" is an abstract and subjective term, without a definitive measurement protocol. Objectives were to analyze Chinese women's self‐perception of skin yellowness and associated parameters and identify objective clinical measurements that correlate with these perceptions. Methods: Following focus group discussions, criteria for skin yellowness were defined, and validated by volunteer rankings of facial images. A typology study of 185 women was performed. Participants were grouped into yellow (Color Uniformity, Brightness and Transparency (CUBT) yellow scale grade > 3, chromameter b* value > 16) and non‐yellow (CUBT yellow scale grade < 2, b* value < 14) groups. Participants self‐evaluated their skin on yellowness, transparency, skin uniformity, dullness, radiance, oiliness, and texture. Expert assessments were performed to grade sebaceous pores, ocular area pigmentation, pigmentary spots and CUBT scores. Instrumental analysis of the skin was employed using corneometer, sebumeter, mexameter chromameter, and AGE reader. Results: Women in the yellow group self‐evaluated their skin as significantly duller, less uniform, and less radiant than women in the non‐yellow group (P ≤ 0.05). Higher levels of ocular area pigmentation and lower facial skin uniformity and brightness (P < 0.001) were observed in women with yellow skin. CUBT expert grading showed lower pink skin color, but significantly higher beige, yellow, and olive pigmentation (P ≤ 0.05) in women in the yellow skin group. Melanin and b* values were significantly higher in women with yellow skin while L value was significantly lower. Conclusion: Self‐perceived skin yellowness in Chinese women correlates to chromameter and mexameter measurements, as well as expert evaluation of ocular pigmentation and CUBT parameters. [ABSTRACT FROM AUTHOR]

Background: Anticipating the postoperative pathological stage and potential for adverse features of prostate cancer (PCa) patients before radical prostatectomy (RP) is crucial for guiding perioperative treatment. Methods: A cohort consisting of three sub‐cohorts with a total of 709 patients has been enlisted from two major tertiary medical centres in China. The primary assessment parameters for adverse pathological features in this study are the pathological T stage, the AJCC prognostic stage groups and perineural invasion (PNI). Logistic regression analyses were performed to investigate the relationship between prostate specific antigen (PSA), its derivatives (incluing Prostate Health Index, phi and phi density, phiD), and the pathological outcomes after RP. Results: Both phi and phiD showed a significant association with pathologic T stage of pT3 or above (phi, adjusted OR, AOR = 2.82, 95% confidence interval, 95% CI: 1.88–4.23, p < 0.001; phiD, AOR = 2.47, 95% CI: 1.76–3.48, p < 0.001) and PNI (phi, AOR = 2.15, 95% CI: 1.39–3.32, p < 0.001; phiD, AOR = 1.94, 95% CI: 1.38–2.73, p < 0.001). In a subgroup analysis with a total PSA value <10 ng/mL, phi and phiD continued to show a significant correlation with pT3 or above (phi, AOR = 4.70, 95% CI: 1.29–17.12, p = 0.019; phiD, AOR = 3.44, 95% CI: 1.51–7.85, p = 0.003), and phiD also maintained its predictive capability for PNI in this subgroup (AOR = 2.10, 95% CI: 1.17–3.80, p = 0.014). Sensitivity analysis indicated that the findings in the combined cohort are mainly influenced by one of the sub‐cohorts, partially attributable to disparities in sample sizes between sub‐cohorts. Combined analysis of phi(D) and multiparametric MRI (mpMRI) data yielded similar results. Conclusions: Preoperative measurement of serum phi and phiD is valuable for predicting the occurrence of adverse pathological features in Chinese PCa patients after RP. [ABSTRACT FROM AUTHOR]

Aims: To evaluate the efficacy, safety, and tolerability of adjunctive lacosamide therapy against focal seizures in young children (1 month – 4 years). Methods: This non‐randomized, open‐label, and self‐controlled real‐world study included 105 children (1 month–4 years) with focal seizures treated with adjunctive lacosamide therapy at Children's Hospital of Chongqing Medical University. Results: (1) The 50% response rates at 3, 6, 9, and 12 months of follow‐up were 58.1%, 61.0%, 57.1%, and 56.2%, while the seizure‐free rates were 27.6%, 34.3%, 32.4%, and 37.1%, respectively. The 50% response rate of the first addition of lacosamide for focal seizures was much higher than the second and later added treatment at 3 months (p = 0.038). After 1 year of follow‐up, these children showed an improvement in neurodevelopmental levels (p < 0.05). (2) Lacosamide retention rate was 72.7% (64/88) after 1 year of follow‐up. Lack of efficacy and serious adverse events were independent risk factors for the lacosamide retention rate. (3) During adjunctive lacosamide therapy, 13 (12.4%) patients reported adverse events and five (4.7%) patients withdrew due to adverse events, including vomiting drowsiness, ataxia (0.94%), neck itching with eczema (0.94%), irritability (1.88%), and gastrointestinal discomfort (0.94%). Conclusion: Adjunctive lacosamide therapy was effective, safe, and well‐tolerated in young Chinese children with focal seizures in this study. [ABSTRACT FROM AUTHOR]

Purpose: Initial studies have suggested that multiple segment (MS) spectacle lenses can reduce the progression rate of childhood myopia and axial eye growth. This paper aimed to compare the effectiveness of two different available designs of MS lens and to explore the nature of their control effect. Method: Published data from the only two clinical trials in which changes in mean spherical equivalent refraction (SER) and axial length (AL) for matched groups of myopic children wearing either MS or single‐vision (SV) spectacle corrections, recorded over a period of at least 2 years, were further analysed and compared. Both trials involved Chinese children of similar ages and visual characteristics, but the trials were located in different cities. The two MS lenses examined were MiyoSmart or DIMS (Hoya) and Stellest (Essilor). Results: Absolute changes in SER and AL differed over time during the two trials. However, if the results were expressed in terms of efficacy over successive 6‐month periods, then the two MS lenses produced broadly similar results (initial efficacy for the control of myopia progression of about 60%–80%, declining over 2 years to about 35%–55%). Control appears to be absolute rather than proportional. Discussion: Myopia control may be due to either the additional myopic defocus induced by the MS lenses (i.e., asymmetry of the through‐focus image changes about the distance focus) or to the general reduction in image contrast that the lenslets create in the peripheral field. Conclusion: Multiple segment spectacle lenses offer a valuable new approach to the control of myopia progression in children. Further work is required to clarify their mechanism of action and to optimise their design parameters. [ABSTRACT FROM AUTHOR]

Little is known in the international academic community about Chinese‐language research on water management. To remedy this deficit, this paper reviews current mainland Chinese understandings of the role of large‐scale water infrastructures as tools of water resources management. We reviewed 461 papers published in mainland Chinese journals by Chinese scholars. This review suggests that the dominant approach to water management reflects the confines of government priorities—large‐scale, concrete‐heavy, infrastructure‐based means of moving water around the country so as to meet demands and stimulate economic growth. Suppression of critical voices means that infrastructure is generally rendered apolitical: the critiques are about practical issues, such as technological, managerial, or administrative problems. There are exceptions to this characterization that adopt more critical frames; however, they reflect on water management elsewhere or in the past rather than on contemporary China. While these more critical papers are interesting and important contributions to our understanding of the politics of hydraulic infrastructures, the literature as a whole says little about the politics of infrastructure in China now. In effect, much of the literature in Chinese on water management in China simply acts as an arm of a machine—a network of corporations, universities, international institutions, and arms of the government, together tasked with identifying and framing what are water management issues, formulating standardized procedures for tackling those issues, and then constructing solutions to them. This article is categorized under:Engineering Water > Planning WaterHuman Water > Water Governance [ABSTRACT FROM AUTHOR]

Objectives: To investigate the knowledge and practices of Chinese doctors in the management of osteoporotic fractures after the Chinese osteoporotic fracture guidelines update and aseries of medical education in 2017. Methods: This was a cross‐sectional survey of doctors in 71 cities across Mainland China. Based on the 2017 Chinese guidelines for the diagnosis and treatment of osteoporotic fractures, a questionnaire was designed and pre‐tested for reliability and validity. Doctors were surveyed with the questionnaire after scientific meetings during February 2017 to January 2018 through WeChat or conference digital platforms or in paper form. Descriptive statistics was used to analyze the responses to the questionnaire. Results: Overall, 314 valid questionnaires were confirmed. Regarding diagnosis, 77% agreed that osteoporosis could be diagnosed once an osteoporotic fracture occurred; 83% believed that the bone mineral density criteria for osteoporosis diagnosis would be T ≤ −2.5 SD. For treatment, almost all (99.7%) agreed with anti‐osteoporosis treatment being one of the basic principles of osteoporotic fracture treatment; 71.6% considered bisphosphonates as the most commonly used anti‐osteoporosis drug; 97% believed that patients who have used anti‐osteoporosis drugs should reassess osteoporosis after osteoporotic fractures instead of discontinue; 95% thought that the patients who did not use anti‐osteoporosis medications before osteoporotic fracture should be treated with anti‐osteoporosis drugs after fracture treatment as early as possible; 89% agreed that the standard use of bisphosphonates after osteoporotic fracture would not affect bone healing adversely; 59% believed the course of bisphosphonates treatment for osteoporosis would be 3–5 years, and 27% considered it to be 1–3 years. The patient follow‐up rate was poor: 46% selected follow‐up rate <30%; only 20% selected follow‐up rate >50%. Only 31% of the hospitals had long‐term management programs for osteoporotic fractures. Conclusions: Doctors generally adhered to the updated Chinese guidelines for osteoporotic fractures; frequent participation in medical education can help doctors to increase their awareness of osteoporosis as well as their acceptance and practice of the guidelines. [ABSTRACT FROM AUTHOR]

Since the late 1970s, China has gradually risen as a global power, which culminates in the present moment when large‐scale geopolitical and economic ventures such as the Belt and Road Initiative have generated diversified cross‐border connections. This is most forcefully felt in the Chinese diaspora, and particularly those in Southeast Asia since the region is home to the largest and most diverse diasporic Chinese population. Chinese voluntary associations (CVAs), as crucial social institutions in the Chinese diaspora, are actively engaging with China's rise and responding to the (trans) regional political‐economic and socio‐cultural changes. In this introduction of the special section, we open up a collection of five research articles and one commentary that discuss the ambivalences and tensions in CVAs' engagement with China's rise. We conceptualize CVAs as ever‐evolving ancestral communities which actively (re)position themselves in relation to complex configurations of power dynamics taking place between actors in China and the Chinese diaspora. Ancestral communities evolve through a constant mediation of the two mutually‐constitutive processes of transnationalization and localization, which take on dual‐facing and double‐embedded orientations. This special section also highlights the continuing significance and renewed engagement of CVAs and potential tensions and conflicts generated in changing geopolitical and domestic environment. [ABSTRACT FROM AUTHOR]

Within the large body of literature on the peer review system for academic journals, there has been limited exploration of the latent functions of review feedback beyond its gatekeeping role. To address this gap, we conducted in‐depth, semi‐structured interviews with 20 Chinese university academics specializing in educational studies. By applying the conceptual frameworks of organizational reputation and academic socialization, we investigated the multifaceted functions of review feedback. Our findings suggest that timely, specific, and constructive feedback are highly valued by Chinese university academics, and journals that provide such review feedback are perceived to possess a higher reputation and are more likely to attract high‐quality submissions. Additionally, Chinese academics see the process of review and revision as a means of professional development since specific and constructive review feedback can lead them to deeper thinking and improve their knowledge of academic norms in their community. Therefore, we emphasize the importance of effective review feedback considering its function of fostering the socialization and professional development of academics while promoting the prosperity of the academic community as a whole. [ABSTRACT FROM AUTHOR]

Although considerable research has explored consumer ethnocentrism and conspicuous consumption effects independently, a meaningful quantitative analysis of the interaction of such effects on consumer perception is yet to be undertaken. This study aims to provide insight into these effects by examining the impacts of consumer ethnocentrism and consumption setting on foreign Country‐of‐Origin (COO) effects in a Chinese consumer wine market context. A total of 324 wine consumers in mainland China participated in a 3 (COO: France vs. Australia vs. China) × 2 (Consumption Setting: Public vs. Private) × continuous (Chinese consumer ethnocentrism) between‐subject, factorial design experiment. The study finds that Chinese consumers favor French red wine when compared with its Australian and Chinese counterparts but shows that Australian wines still benefit through smaller, indirect COO effects. Additionally, French COO effects are mediated by the utilitarian and hedonic meanings of red wine and moderated by consumer trait ethnocentrism and the consumption setting. This paper contributes to the understanding of culturally informed self‐regulation of consumer behaviors and how Chinese consumer ethnocentrism interacts with consumption settings to alter a consumer's perception of foreign goods. The findings of this paper also provide practical insight into Chinese wine consumers' perceptions and decision‐making processes for wine exporters. [ABSTRACT FROM AUTHOR]

Immigrant‐run businesses are playing an increasingly important role in the Polish economy. This paper focuses on the patterns of entrepreneurship and ethnic economy employment among Chinese and Vietnamese immigrants residing in the Warsaw metropolitan area (WMA). It uses microdata from a survey of Vietnamese and Chinese residents of the WMA and employs logistic regression analysis in order to assess the factors that affect the odds of entrepreneurship and ethnic economy employment among them. Subsequently, the paper analyses the impact of entrepreneurship and ethnic economy employment on the earnings of Vietnamese and Chinese citizens living in the WMA. Empirical analysis demonstrates that Vietnamese and Chinese immigrants are not pushed to become entrepreneurs by an opportunity structure that blocks alternative options and enjoy significantly higher incomes than native‐born Polish citizens. The ethnic economy becomes a temporary adjustment mechanism for newly arrived migrants but is not lucrative for longer‐term residents of these two origins. [ABSTRACT FROM AUTHOR]

Our previous study reckons that the impact of the rs1801133 variant of 5,10‐methylenetetrahydrofolate reductase (MTHFR) on coronary artery disease (CAD) is possibly mediated by cardiometabolic disorder. This study is performed to verify this hypothesis. Four hundred and thirty CAD patients and 216 CAD‐free individuals were enrolled in this case–control study. The rs1801133 variant was genotyped by PCR‐RFLP. Severity of coronary lesions was evaluated by number of stenotic coronary vessels and extent of coronary stenosis. The rs1801133 T allele significantly increased homocysteine levels in patients with CAD and CAD‐free individuals. Individuals with the T allele of rs1801133 had an increased risk of developing CAD. In contrast, individuals with the TT genotype of rs1801133 were at high risk of multiple vessel lesions. The carriers of CT genotype had higher levels of systolic blood pressure (SBP), low‐density lipoprotein cholesterol (LDL‐C), and high‐sensitivity C‐reactive protein (hs‐CRP), and lower levels of apolipoprotein A1 (APOA1) than those with CC genotype in male patients with CAD. The receiver operating characteristic (ROC) curve and precision‐recall (PR) curve indicated that hyperhomocysteinemia was sensitive to predict the severity of CAD. Multivariate logistic regression revealed that homocysteine, rs1801133, age, smoking, weight, body mass index (BMI), lipoprotein(a) [Lp(a)], and hs‐CRP were independent risk factors for CAD. The increased risk of CAD and severity of coronary lesions associated with rs1801133 in the Chinese Han population were attributed, at least partly, to high homocysteine levels. Hyperhomocysteinemia had a high predictive value for severe CAD or multiple vessel lesions. [ABSTRACT FROM AUTHOR]

Background: Vulvovaginal atrophy (VVA) includes a wide range of conditions affecting the reproductive and urinary systems, often requiring careful evaluation and management for optimal health. Aims: This study aims to evaluate the symptom management effects of a real time temperature‐monitored non‐ablative RF device for the treatment of postmenopausal Chinese women with VVA symptoms. Methods: This pilot study involved 24 postmenopausal Chinese women with one or more VVA symptoms, who wished to remain sexually active. VHIS, VAS, and FSFI were used to track and evaluate various aspects of the patient's condition. Analyses were conducted at the end of the study to verify the statistical significance of the treatment's results. Results: All patients reported substantial, statistically significant, improvements on every VVA symptom tracked. Approximately 80% of the patients reported total symptom reversal at 12‐week post‐treatment follow‐up. Conclusion: This pilot study demonstrated that non‐ablative, monopolar RF technology equipped with real time temperature monitoring is feasible and safe in the treatment of postmenopausal women with VVA symptoms, and efficacious at up to 12 weeks post‐treatment. [ABSTRACT FROM AUTHOR]

Background: The assessment of skin aging through skin measurements faces limitations, making perceived age evaluation a more valuable and direct tool for assessing skin aging. Given that the aging process markedly affects the appearance of the eye contour, characterizing the eye region could be beneficial for perceived age assessment. This study aimed to analyze age‐correlated changes in the eye contour within the Chinese Han female population and to develop, validate, and apply a multiple linear regression model for predicting perceived age. Materials and methods: A naïve panel of 107 Chinese women assessed the perceived ages of 212 Chinese Han women. Instrumental analysis evaluated periorbital parameters, including palpebral fissure width (PFW), palpebral fissure height (PFH), acclivity of palpebral fissure (AX), angle of inner canthal (AEN), and angle of outer canthal (AEX). These parameters were used to construct a multiple linear regression model for predicting the perceived ages of Chinese Han women. A combined treatment using Fotona 4D and an anti‐aging eye cream, formulated with plant extracts, peptides, and antioxidants, was conducted to verify the cream's anti‐aging efficacy and safety. This eye cream was then tested in a large‐scale clinical trial involving 101 participants. The prediction model was employed in this trial to assess the perceived ages of the women after an 8‐week application of the eye cream. Results: All parameters were observed to decrease with age. An intergroup comparison indicated that eyelid aging in Chinese Han women accelerates beyond the age of 50. Consequently, a linear regression model was constructed and validated, with the perceived age being calculated as 183.159 ‐ 1.078 * AEN ‐ 4.487 * PFW + 6.061 * PFH ‐ 1.003 * AX ‐ 0.328 * AEX. The anti‐aging efficacy and safety of the eye cream were confirmed through combined treatment with Fotona 4D, showing improvements in wrinkles, elasticity, and dark circles under the eyes. In a large‐scale clinical evaluation using this eye cream, a perceived age prediction model was applied, suggesting that 8 weeks of use made participants appear 2.25 years younger. Conclusion: Our study developed and validated a multiple linear regression model to predict the perceived age of Chinese Han women. This model was successfully utilized in a large‐scale clinical evaluation of anti‐aging eye cream, revealing that 8 weeks of usage made participants appear 2.25 years younger. This method effectively bridges the gap between clinical research and consumer perceptions, explores the complex factors influencing perceived age, and aims to improve anti‐aging formulations. [ABSTRACT FROM AUTHOR]

Background: Photo‐ageing is a form of skin ageing which affects the entire face. A photo‐aged skin has a diverse variety of wrinkles and dyspigmentation all over the face. Here, we discuss photo‐ageing on the Chinese skin evaluated using a photo‐numeric scale developed and validated on Caucasian skin (i.e., Caucasian scale) and evaluated using a photo‐numeric scale developed and validated on Korean skin (i.e., Korean scale). The Korean scale can be subdivided into two scales that separately address the wrinkling and dyspigmentation constituents of photo‐ageing. Aim: As there are currently no photo‐ageing scales for Chinese skin, the main objective of this study is to adapt existing photo‐ageing photo‐numeric scales for use on ethnic Chinese skin. Method: Three trained assessors studied facial photo‐ageing on 1,081 ethnic Chinese young adults from the Singapore/Malaysia Cross‐sectional Genetics Epidemiology Study (SMCGES) cohort. Results: All assessors are highly internally consistent (Weighted Kappa (κw) values≥0.952). We found that the Caucasian scale and Korean scale give nearly synonymous results for the wrinkling constituent of photo‐ageing (R2 = 0.9386). The two scales are strongly concordant (Spearman's Rank Correlation (ρ) value: 0.62 ± 0.06, p = 1.31×10−84). A weak‐to‐moderate inter‐scalar level of agreement (Cohen's Kappa (κ) values: 0.38 ± 0.05, p = 8.87×10−53) persists and is statistically significant after accounting for agreements due to chance. When tested on ethnic Chinese skin, both scales detect photo‐ageing consistently (Area under curve [AUC] values: 0.76‐0.84). Additionally, the Korean scale for the dyspigmentation constituent of photo‐ageing is concordant with both the Caucasian scale (R2 = 0.7888) and the Korean scale for the wrinkling constituent of photo‐ageing (R2 = 0.7734). Conclusion: Our results show that the Caucasian scale is suitable for capturing photo‐ageing on Chinese skin, especially wrinkle variations. The Korean dyspigmentation scale supplements the Caucasian scale to capture dyspigmentation patterns on Chinese skin that may be absent on Caucasian skin. Currently, photo‐ageing scales for Chinese skin are absent. When developed, these photo‐ageing scales must be properly validated for their ability to capture photo‐ageing of the entire face. [ABSTRACT FROM AUTHOR]

Background: Severe acute respiratory syndrome coronavirus 2 disease (COVID‐19) has caused a worldwide challenging and threatening pandemic. We aimed to assess the safety and efficacy of the COVID‐19 vaccines in Non‐Small Cell Lung Cancer (NSCLC) patients. Methods: Patient self‐reported adverse events related to vaccines were recorded by follow‐up through a uniform questionnaire. Survival analysis was performed by Kaplan–Meier method. A multivariate analysis was performed by the Cox proportional hazard regression model to determine the effect of each variable on the survival of lung cancer patients. Results: A total of 860 patients with NSCLC on treatment were enrolled. Mean age was 57 years in patients with early stage group and 62 years in advanced stage group. The vaccination rate was 71.11% for early‐stage patients and 19.48% for advanced‐stage patients; most of them (86.5%) received the COVID‐19 inactivated virus (Vero cell) vaccine (Coronavac; Sinovac). The most common systemic adverse reaction was weakness. The main reason for vaccine refusal in those unvaccinated patients was concern about the safety of vaccination in the presence of a tumor and undergoing treatment (56.9% and 53.4%). The 1‐year disease‐free survival (DFS) rate was 100% for vaccinated and 97.4% for unvaccinated early‐stage patients. Then we compared the progression‐free survival (PFS) of vaccinated (median PFS 9.0 months) and unvaccinated (median PFS 7.0 months) advanced stage patients (p = 0.815). Advanced NSCLC patients continued to be divided into groups receiving radio‐chemotherapy, immunotherapy, and targeted therapy, with no statistical difference in PFS between the groups (p > 0.05). The median overall survival (OS) of vaccinated patients was 20.5 months, and that of unvaccinated patients was 19.0 months (p = 0.478) in advanced NSCLC patients. Conclusions: COVID‐19 vaccination is safe for Chinese NSCLC patients actively receiving different antitumor treatments without increasing the incidence of adverse reactions, and vaccination does not affect cancer patient survival. [ABSTRACT FROM AUTHOR]

Objective: The goal of the study was to examine the genetic correlation of cluster of differentiation 14 (CD14) gene polymorphisms with peri‐implantitis (PI) predisposition in a Chinese Han population. Methods: In the case‐control study, blood samples were collected from PI patients and healthy individuals (n = 120/group), who were admitted to the Affiliated Hospital of Yangzhou University from 2021 to 2023. One‐way analysis of variance (ANOVA) was applied to compare differences of continuous variables among different groups. Genotype and allele distributions of CD14 gene rs2569190 and rs2915863 polymorphisms were analyzed between groups via χ2 test. Results: A high percentage of rs2569190 GG genotype or G allele carriers were identified in PI group compared with control group (p <.01). Rs2569190 GG genotype carriers had high risk to develop PI (odds ratio: 2.545, 95% confidence interval: 1.257–5.156, p =.009). The rs2569190 AA genotype carriers had the lowest values of gingival index, plaque index, calculus index, peri‐implant pocket depth, and clinical attachment level, which were the highest in cases with GG genotype. Conclusion: Rs2569190 polymorphism of CD14 gene was significantly associated with PI predisposition in the Chinese Han population, and the GG genotype and G allele were risk factors for the development of PI. [ABSTRACT FROM AUTHOR]

Background: Filling therapy is becoming increasingly popular for correcting tear trough deformities (TTD). However, its therapeutic effect and retention time are limited. Aims: To improve the clinical efficacy and safety of TTD treatment in Asians, we used a blunt separation technique to break the adhesion site of periorbital subcutaneous tissue, and while repairing skin dermis after injury, it was combined with uncrosslinked hyaluronic acid compound solution to promote collagen regeneration and treat TTDs. Patients/Methods: Twenty‐six Chinese patients (21 women and 5 men) with TTD, with a mean age of 34.54 ± 9.21 (range, 20–56) years, were enrolled. Symptom improvement, recurrence rates, treatment safety, and patient satisfaction were evaluated. Results: All patients' tear trough rating scale (TTRS) scores decreased significantly immediately after treatment. The TTRS scores at 1, 3, and 6 months, and 1 year after treatment demonstrated significant differences from those before treatment (all p < 0.05). All patients' experienced mild pain, erythema, and swelling during the treatment. Three patients developed postinjection bruising after treatment, which lasted for 6–7 days and subsequently disappeared. No other adverse reactions were observed during the follow‐up. There were no recurrent cases, and patient satisfaction was very high. Conclusions: Blunt separation combined with an uncrosslinked sodium hyaluronate composite solution is safe and effective for treating TTDs in Asians with few side effects and has good clinical application prospects. [ABSTRACT FROM AUTHOR]

Background: Limited research has been conducted regarding the elucidation of genotype–phenotype correlations within the 20q13.33 region. The genotype–phenotype association of 20q13.33 microdeletion remains inadequately understood. In the present study, two novel cases of 20q13.33 microdeletion were introduced, with the objective of enhancing understanding of the genotype–phenotype relationship. Methods: Two unrelated patients with various abnormal clinical phenotypes from Fujian province Southeast China were enrolled in the present study. Karyotype analysis and chromosomal microarray analysis (CMA) were performed to investigate chromosomal abnormalities and copy number variants. Results: The results of high‐resolution G‐banding karyotype analysis elicited a 46,XY,der(20)add(20)(q13.3) in Patient 1. This patient exhibited various clinical manifestations, such as global developmental delay, intellectual disability, seizures, and other congenital diseases. Subsequently, a 1.0‐Mb deletion was identified in the 20q13.33 region alongside a 5.2‐Mb duplication in the 14q32.31q32.33 region. In Patient 2, CMA results revealed a 1.8‐Mb deletion in the 20q13.33 region with a 4.8‐Mb duplication of 17q25.3. The patient exhibited additional abnormal clinical features, including micropenis, congenital heart disease, and a distinctive crying pattern characterized by a crooked mouth. Conclusion: In the present study, for the first time, an investigation was conducted into two novel cases of 20q13.33 microdeletion with microduplications in the 17q25.3 and 14q32.31q32.33 regions in the Chinese population. The presence of micropenis may be attributed to the 20q13.33 microdeletion, potentially expanding the phenotypic spectrum associated with this deletion. [ABSTRACT FROM AUTHOR]

Annually, around 10 million Chinese tourists, constituting almost a quarter of Thailand's total foreign visitors (before COVID‐19), have started to make a strong imprint on Thailand's tourist landscape. At the same time, a new wave of Chinese migrants to Thailand are seeking business and work opportunities. This paper focuses on these new encounters between local Thais and the incoming mainland Chinese in terms of how cultural boundaries are created, contested and renegotiated, specifically within the context of Thailand's long history of Chinese migration, which dates back several generations. The paper investigates the phenomenon of 're‐Sinicization' in Thailand, and its contested nature within the broader Thai political and cultural milieu. It draws upon recent controversies regarding online battles between Thai and Chinese netizens to argue that the controversies are indicative of the unease from the increasing Chinese presence within Thai society and the increasing embroilment of Thailand within the political contestation of the wider Sinosphere. [ABSTRACT FROM AUTHOR]

With the development of the times, the exchanges between countries are increasing. China is becoming a superpower, and the number of international cities is increasing. This requires the communication level of Chinese people to be improved. English, as the second largest communication language in China, should be better understood and studied. This paper makes an in-depth discussion on the optimization and evaluation of oral English CAF based on artificial intelligence and corpus and makes an experimental analysis. The results are as follows: (1) introducing oral English teaching based on artificial intelligence and oral English based on a corpus, so as to deepen the public's cognition of both and make oral English more deeply rooted in people's hearts and get attention. (2) Analyzing the algorithms of phoneme errors in spoken English. Errors in spoken English are very common. Algorithms can be used to identify them better. When evaluating spoken English, algorithms are needed to evaluate them more accurately. (3) There are many examples of the benefits of artificial intelligence to oral English teaching. By comparison, it is found that the method of evaluating using artificial intelligence is more accurate, a corpus can improve oral English, and CAF optimization is also of great help to oral English. [ABSTRACT FROM AUTHOR]

This paper aims to investigate Chinese people's willingness to stay in the city where they work when the Spring Festival meets the COVID-19 pandemic. Specifically, a stated choice experiment about intercity travel including three homecoming trips (i.e., trips carried by conventional railway, high-speed railways, and private car) and the option "stay in place" was designed. Respondents were requested to choose the most preferred alternative in the context of the current situation of the COVID-19 pandemic and relevant policies. Based on the data collected from 800 respondents, a latent class mixed logit model was developed and estimated to capture the potential correlations within alternatives and respondents and the preference heterogeneity between respondents. Two latent classes were identified, one of which paid more attention to epidemic prevention policies while the other cared more about the characteristics of homecoming trips. Results show that people's willingness to stay in the city of work is largely dependent on epidemic prevention policies in their hometowns and decisions of social network members. [ABSTRACT FROM AUTHOR]

Resting upon an extensive data set on foreign invested enterprises (FIEs) in China, we investigate the role of institutional difference in determining the locational choice of foreign direct investment (FDI). Estimation results using firm‐level discrete choice model suggest that FIEs from source countries that are more remote institutionally from the Chinese mainland exhibit a higher degree of sensitivity to regional economic institutions in their choice of FDI location. Furthermore, we find that FIEs coming from countries with better institutions than China are more sensitive to the institutional difference. Interestingly, we find that the deterrent effect of institutional distance on FDI entry is mitigated for FIEs coming from countries with more ethnic Chinese individuals in their overall populations. [ABSTRACT FROM AUTHOR]

Despite heightened scholarly attention paid to transnational immigrant families since the 1990s, a systematic analysis framework explaining the formation of these family experiences has been absent. Building on a 3‐year qualitative research project (2017–2020) investigating the multigenerational dynamics of new Chinese immigrant families from the People's Republic of China living in New Zealand, through exploring the formation of the seasonal parents/grandparents phenomenon within those families, this paper introduces an analysis framework to systematically interrogate the factors shaping diverse transnational family experiences. The proposed analysis framework builds upon an inclusive paradigm, which allows the future investigation of transnational family experience to trace multilevel impact factors behind its formation (i.e., microlevel family dynamics, mesolevel living environment and macrolevel institutional foundations). Additionally, it also highlights the interactivity of those diverse impact factors within and across different levels, as well as the spatial and temporal dimensions of transnational family lives. [ABSTRACT FROM AUTHOR]

There are about 10 million people with epilepsy (PWE) in China. In addition to therapies approved by the National Medical Products Administration, the use of complementary and alternative medicine (CAM) is prevalent in Chines PWE. These CAM therapies mainly comprise traditional Chinese medicine herbs (TCMHs), acupuncture, and music. A retrospective literature search was performed to summarize the updates of CAM in China in the past ten years, and sixty‐two papers were finally included. In this following review, we listed the animal and clinical studies to summarize the antiepileptic mechanisms and clinical efficacy of CAM in Chines PWE. The main mechanisms of TCMHs and acupuncture included regulation of neurotransmitters and receptors, voltage‐gated ion channels modulation, expression of apoptosis‐related genes, antioxidant response, and anti‐inflammation. Although there were enormous clinical studies on them, the current available clinical trials were small, short‐term, heterogeneous, and had a high risk of bias. With regard to music, a few studies conducted by Chinese scholars suggested that it was beneficial for PWE as an add‐on therapy, which was consistent with the results of foreign studies. Further randomized clinical trials in large populations are required to prove the effectiveness and safety of CAM. [ABSTRACT FROM AUTHOR]

Culture is a powerful spiritual force rooted in the hearts of the Chinese people and guides the direction of the Chinese people. Sight singing and ear training are playing an increasingly important role as an important means of music teaching. The article is aimed at studying the latest application progress of music reading skills in audiovisual ear training in the new media environment. This paper proposes the interactive application of music reading skills that integrate new media to realize the interactive communication between man and machine. The experimental results of this paper show that new media can make greater use of the advantages of music reading skills, enhance students' musical sensitivity by 20%, and realize musical interaction. [ABSTRACT FROM AUTHOR]

Background: Wrinkle formation is the most visible characteristic of facial aging. Radiofrequency (RF) technology is currently utilized to reduce facial wrinkles and contribute to skin rejuvenation. Objective: To analyze the efficacy and safety of a noninvasive, home‐based RF device applied for facial rejuvenation in Chinese people. Methods: A single‐center, open‐label, intraindividual controlled trial was performed on subjects who received an 8‐week treatment of the RF device. A total of 22 female individuals aged 25–60 years with Fitzpatrick skin type III–IV were enrolled. Efficacy of treatment was subjectively evaluated using the Fitzpatrick Wrinkle Classification Scale (FWCS) assessed by physician or overall satisfaction of subject with a 10‐point VAS, and objectively using the skin ultrasound examination as well as the 3D skin analysis system. Adverse event was recorded at each visit. Results: In comparison with the baseline, evaluator‐assessed FWCS scores showed significant improvement at 4 weeks (p < 0.005) and 8 weeks (p < 0.005) after treatment. All subjects reported different degrees of improvement in facial wrinkles after 8 weeks of treatment. The results of skin ultrasound examination revealed significant increase of the dermal thickness at week 8 (p < 0.05) as compared to the baseline. In addition, a significant decrease in the proportion and density of perioral wrinkles evaluated by the 3D skin analysis system was observed from baseline to week 4. The treatment was well‐tolerated, and no serious adverse event was observed. Conclusion: This noninvasive, home‐based RF device was effective in improving skin texture and elasticity with a safe and well‐tolerated treating procedure. [ABSTRACT FROM AUTHOR]

Objective. To analyse the clinical and pathologic features, discuss therapeutic strategies, and possibly cause and identify prognostic factors of scrotal basal cell carcinoma (BCC) in Chinese patients. Materials and Methods. Between January 2012 and December 2022, 12 patients with scrotal BCC were diagnosed and treated at our institution. A review was conducted based on the clinical characteristics, pathology slides, and tissues of these patients. Results. The median patient age was 69.26 ± 11.23 years. The skin lesions presented as red papules, blue-grey polypoid nodules, erythematous patches, brownish plaques, and so on. All patients were treated using wide excision, but the margins varied from 0.5 cm to 2 cm. HPV infection was checked in all lesions, with 4 out of 12 testing positive for P16 and 1 for HPV16 DNA. We found mottled positive expression of P16 in the cytoplasm and membrane. One patient developed left inguinal lymph node metastasis and was successfully treated using bilateral inguinal lymphadenectomy. The rest recovered well without relapse. Conclusions. BCC of the scrotum is rare, but long-term surveillance is recommended for BCC patients, and whether genital HPV infection is a noteworthy feature for these patients remains under investigation. [ABSTRACT FROM AUTHOR]

This study seeks to clarify nationwide management status and spatial utilization characteristics of day‐service‐centers that can provide Chinese language service in Japan. A comprehensive survey was conducted through mail questionnaires targeting the 115 day‐service‐centers that can provide Chinese language service in Japan, with the objective of explicating their current operational and utilization situations. Additionally, field behavioral observation surveys were carried out in 2 day‐service‐centers, 1 is for Chinese people in Japan or Japanese people from China and the other is for Japanese people. The purpose was to identify the behavioral difference between Chinese users and Japanese users and identify the spatial utilization characteristics in 2 day‐service‐centers. [ABSTRACT FROM AUTHOR]

Background: Rare and novel variants of HBA1/2 and HBB genes resulting in thalassemia and hemoglobin (Hb) variants have been increasingly identified. Our goal was to identify two rare Hb variants in Chinese population using third‐generation sequencing (TGS) technology. Methods: Enrolled in this study were two Chinese families from Fujian Province. Hematological screening was conducted using routine blood analysis and Hb capillary electrophoresis analysis. Routine thalassemia gene testing was carried out to detect the common mutations of α‐ and β‐thalassemia in Chinese population. Rare or novel α‐ and β‐globin gene variants were further investigated by TGS. Results: The proband of family 1 was a female aged 32, with decreased levels of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), Hb A2, and abnormal Hb bands in zone 5 and zone 12. No common thalassemia mutations were detected by routine thalassemia analysis, while a rare α‐globin gene variant Hb Jilin [α139(HC1)Lys>Gln (AAA>CAA); HBA2:c.418A>C] was identified by TGS. Subsequent pedigree analysis showed that the proband's son also harbored the Hb Jilin variant with slightly low levels of MCH, Hb A2, and abnormal Hb bands. The proband of family 2 was a male at 41 years of age, exhibiting normal MCV and MCH, but a low level of Hb A2 and an abnormal Hb band in zone 12 without any common α‐ and β‐thalassemia mutations. The subsequent TGS detection demonstrated a rare Hb Beijing [α16(A14)Lys>Asn (AAG>AAT); HBA2:c.51G>T] variant in HBA2 gene. Conclusion: In this study, for the first time, we present two rare Hb variants of Hb Jilin and Hb Beijing in Fujian Province, Southeast China, using TGS technology. [ABSTRACT FROM AUTHOR]

Background: Newborn screening (NBS) aims to detect congenital anomalies, and next‐generation sequencing (NGS) has shown promise in this aspect. However, the NBS strategy for monogenic inherited diseases in China remains insufficient. Methods: We developed a NeoEXOME panel comprising 601 genes that are relevant to the Chinese population found through extensive research on available databases. An interpretation system to grade the results into positive (high‐risk, moderate‐risk, and low‐risk genotypes), negative, and carrier according to the American College of Medical Genetics (ACMG) guidelines was also developed. We validated the panel to evaluate its efficacy by using data from the "1000 Genomes Project" and conducted a pilot multicenter study involving 3423 neonates. Results: The NGS positive rate in the 1000 Genomes Project was 7.6% (23/301), whereas the rate was 12.0% in the multicenter study, including 3249 recruited neonates. Notably, in 200 neonates, positive per conventional NBS, 58.5% (69/118) showed results consistent with NGS. In the remaining 3049 neonates showing negative results in conventional NBS, 271 (8.9%) were positive per NGS, and nine of them were clinically diagnosed with diseases in the follow‐up. Conclusion: We successfully designed a NeoEXOME panel for targeted sequencing of monogenic inherited diseases in NBS. The panel demonstrated high performance in the Chinese population, particularly for the early detection of diseases with no biochemical markers. [ABSTRACT FROM AUTHOR]