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Despite the relevance and prevalence of research that produced knowledge about stigmatised groups and communities throughout the 1980s and 1990s, in the United States, studies that investigated the relationship between HIV/AIDS, intersectional stigma, and health-illness status among groups considered hegemonic are incipient—i.e., heterosexual, and white groups, who did not suffer stigma due to sexuality and race/colour, for example. In this study, such a gap is examined in order to observe the effects of stigma in non-exposed communities. Additionally, the article (i) explores the formation of a pioneering group of caregivers in New York City, the Mothers of Patients with AIDS (MPWA), created in 1986; and (ii) analyses narratives about health disease from a collective care agenda established by middle-aged and elderly mothers dealing with the challenges and needs of adult children and people with moderate and high degrees of dependence. This study is part of a larger project that investigated the emergence of non-profit organisations and gerontology care groups in the context of the HIV-AIDS epidemic in New York in the 1980s and 1990s. Documentary research was developed in the Florence Rush collection, made available by the Arthur and Elizabeth Schlesinger Library at Harvard University’s Radcliffe Institute for Advanced Study. The selected materials bring together qualitative empirical sources from reports, personal histories, and interviews conducted by Florence Rush and other mothers, social workers, and health professionals. As the results attest, the narratives produced by Florence Rush’s interlocutors during the AIDS health crisis make it possible to understand how social and cultural dynamics of recognising the disease did not result in autonomous, individual, and objective processes for exposing the pathological state. The strategic use of the term “cancer” instead of “AIDS” as an umbrella definition, and one less demarcated by aspects involving gender and sexual behaviour, evidenced the sociality of the illness. Conclusions show how negative representations were associated with AIDS—perceived as harmful, immoral, or deviant behaviours — and produced new meanings and demands among patients who feared stigmatising classifications in the midst of sexual panic until the commercial availability of the antiretroviral cocktail in 1997. [ABSTRACT FROM AUTHOR]

This research aims to explain and analyze Indonesia's decision to buy the Dassault Rafale fighter aircraft from France in 2022. It is known that Indonesia will retire its old F-5 Tiger fighter aircraft and its outdated technology. Indonesia's purchase of Dassault Rafale fighter aircraft to increase air defense capabilities, strengthen bilateral cooperation and increase national military capabilities. Several options for Indonesia to choose which fighter aircraft to buy, namely Gripen from Sweden, Eurofighter from Austria, Dassault Rafale from France, and Sukhoi Su-35 from Russia. The theory used in this research is Rational Choice. This study used descriptive qualitative method. In this research, data collection techniques were carried out by collecting data through available literature and library materials, mass media, print media, electronic media, books, journals and related articles, as well as other open sources. The results of this research show that Indonesia's decision to buy the Dassault Rafale fighter aircraft from France was based on two considerations, namely economic considerations where maintenance costs are low, technology transfer, and the potential to increase the national defense industry, increasing independence in the production and maintenance of military defense equipment and political considerations, namely diplomatic relations, regional security and national strategic interests. This choice reflects efforts to strengthen defense and build close military collaboration with partner countries. [ABSTRACT FROM AUTHOR]

Harlow Gale is often depicted as the first experimentalist in advertising thought. This positioning elides influences which impacted upon his thinking. In this article, we outline Gale's involvement with psychical research and its implications for advertising. These narratives are situated within a genealogy of subliminal processes across advertising and marketing theory from the late nineteenth century through to social cognition studies today. Gale's connection with psychical research, in conjunction with early practitioner reflections on the unconscious, formed the enabling conditions for his major contributions to advertising. Psychical scholarship spotlighted the centrality of the "multiplex self" to human functioning. While psychical framings scaffolded Gale's empirical, conceptual, and theoretical work, it also limited greater engagement with his insights. However, subsequent modifications of advertising theory and practice are underwritten by levels of continuity and discontinuity that facilitate the identification of psychically indebted bodies of thought from Gale's time to the present day. Taken together, these analytic associations provide a substantive reorientation of historical and contemporary accounts of advertising theory and practice. [ABSTRACT FROM AUTHOR]

The document provides information on East Asian libraries in North American institutions for the fiscal year 2022-2023. It includes data on physical and electronic collections, fiscal support, staffing, and public services. The document highlights specific collections and acquisitions at certain institutions and mentions challenges faced by some libraries. It also provides contact information for libraries conducting research on East Asian studies. The document offers a comprehensive overview of the East Asian library collections and resources available at these institutions. [Extracted from the article]

Technology in libraries has played an essential role in serving today's communities. This study provides an overview of the integrated library systems/software (ILSs) used in libraries in South Sulawesi, Indonesia. It aims to highlight the strengths and possibilities of ILSs and briefly explain their advantages and disadvantages along with the cost of implementation. The data was gathered from questionnaires sent via an online survey and from direct interviews with certain academic libraries over the period of 2019 to 2020. Fifty-three of 67 libraries that fulfilled the study have implemented an ILS. To deeply understand the application, a direct interview with some libraries was conducted to learn the advantages and disadvantages. The result of the study showed that the most used ILSs are SLiMS and INLISlite and other programs like Apollo, Athenium Light, Simpus, Spektra, Jibas, KOHA, and Openlibrary. The budget spent is an average of300 USD. While the ILSs have helped these libraries improve services, IT expertise and adequate resources are needed, especially when the systems present problems. An easy-to-use system that costs less will potentially be used in this area of research. This study will be particularly helpful for any library in Indonesia. These findings may also be generalized to libraries in other countries facing economic and technological similarities. [ABSTRACT FROM AUTHOR]

This paper investigates the potential of the Gamified Metaverse as a platform for promoting library services. The study compares the effectiveness of a traditional library program with a Metaverse- based library program in terms of knowledge acquisition and library anxiety. The research also examines students' perceptions of implementing gamification within the context of the Gamified Metaverse platform. A mixed-methods approach was adopted, including pre- and post-test analysis, statistical analysis, and qualitative data collection. The results indicate that both the traditional and Metaverse-based library programs effectively increased the participants' knowledge, with no significant difference between the two approaches. However, the Metaverse-based program was found to be less effective in facilitating interaction with librarians and reducing library anxiety. Additionally, students expressed positive perceptions of implementing gamification in the Gamified Metaverse platform, finding it engaging and motivating. These findings contribute to the understanding of the effect of the Metaverse as a tool for promoting library services and enhancing knowledge acquisition. However, it is not as effective in reducing library anxiety, particularly in terms of interaction with librarians and staff. It should be noted that the platform may have limitations such as high costs and potential side effects of virtual reality, making it more suitable as an additional tool for promoting library services, taking into account its feasibility and potential benefits for specific student populations and larger libraries. [ABSTRACT FROM AUTHOR]

Despite the growing evidence that the modern world is more diverse and so is the nature of relationships that present in therapy, there remains paucity of empirical evidence on how cultural differences impact those in intercultural romantic ties. We conducted this comprehensive scoping review with the aim to outline the size and scope of existing research in the field of intercultural love and romantic relationships. We utilised a five-stage scoping review protocol provided by the Joanna Briggs Institute (JBI) manual for synthesis of evidence for a scoping review to ensure the rigour, transparency, and replicability of our findings. We reviewed peer-reviewed articles across nine electronic databases as well as "snowballing" the literature from the reference lists. A total of 46 studies were included in this review. We found that the majority of studies approached intercultural relationships from the deficit perspective, focusing on the domains of cultural difference that bring challenges to the relationship. These included culture-rooted differences in parenting standards and gender role expectations, among others. Often, cultural differences were found to bring power impedance into the relationship. Open communication and flexibility were found as important coping strategies. Differences in native language posed challenges to emotional communication between partners. These findings demonstrate that intercultural relationships face an additional layer of challenges and complexities that have to be recognised in therapy. We propose four domains of transmodality relational competencies on the basis of our findings to inform culturally sensitive therapeutic practice. [ABSTRACT FROM AUTHOR]

The article offers information on the evolution of Film Quarterly since 1977, noting its format change to include full-size print versions, downloadable PDFs, and a public-facing website. Topics include the expansion of the journal's content to encompass forms of visual culture beyond film and television, such as apps, video games, VR, and AI-assisted computational imaging.

With 1 in 44 children in the United States meeting the criteria for an autism diagnosis, it is likely that most, if not all, school librarians will have some contact with a student with autism spectrum disorder (ASD). One potential avenue for such education is through professional development opportunities such as state library conferences, in which school librarians share information with one another in forums such as breakout and poster sessions, while also attending keynote and sponsored presentations. To expand upon previous research related to training of school librarians in the area of ASD, this content analysis examines state library conference programs to determine if information is being shared through such conferences about autism and disability. Conferences from nine states, over a 5-year period, were analyzed for key terms related to autism and disability. Findings reveal few opportunities for school librarians to learn about autism and disability through sessions presented at state conferences, despite a previously established interest and need. [ABSTRACT FROM AUTHOR]

This study examined how well people can recognize and relate to animated pedagogical agents of varying ethnicities/races and genders. For both Study 1 (realistic-style agents) and Study 2 (cartoon-style agents), participants viewed brief video clips of virtual agents of varying racial/ethnic categories and gender types and then identified their race/ethnicity and gender and rated how human-like and likable the agent appeared. Participants were highly accurate in identifying Black and White agents but were less accurate for Asian, Indian, and Hispanic agents. Participants were accurate in recognizing gender differences. Participants rated all types of agents as moderately human-like, except for White agents. Likability ratings were lowest for White and male agents. The same pattern of results was obtained across two independent studies with different participants and different onscreen agents, which indicates that the results are not solely due to one specific set of agents. Consistent with the Media Equation Hypothesis and the Alliance Hypothesis, this work shows that people are sensitive to the race/ethnicity and gender of onscreen agents and relate to them differently. These findings have implications for how to design animated pedagogical agents for improved multimedia learning environments in the future and serve as a crucial first step in highlighting the possibility and feasibility of incorporating diverse onscreen virtual agents into educational computer software. [ABSTRACT FROM AUTHOR]

Synthetic biology aims to engineer transgene switches for precise therapeutic protein control in cell‐based gene therapies. However, off‐the‐shelf trigger‐inducible gene circuits are usually switched on by single or structurally similar molecules. This study presents a mammalian gene‐switch platform that controls therapeutic gene expression by a wide range of molecules generating low, non‐toxic levels of reactive oxygen species (ROS). In this system, KEAP1 (Kelch‐like ECH‐associated protein 1) serves as ROS sensor, regulating the translocation of NRF2 (nuclear factor erythroid 2‐related factor 2) to the nucleus, where NRF2 binds to antioxidant response elements (ARE) to activate the expression of a gene of interest. It is found that a promoter containing eight‐tandem ARE repeats is highly sensitive to the low ROS levels generated by the soluble and volatile molecules, which include food preservatives, food additives, pharmaceuticals, and signal transduction inducers. In a proof‐of‐concept study, it is shown that many of these compounds can independently trigger microencapsulated engineered cells to produce sufficient insulin to restore normoglycemia in experimental type‐1 diabetic mice. It is believed that this system greatly extends the variety of small‐molecule inducers available to drive therapeutic gene switches. [ABSTRACT FROM AUTHOR]

SARS-CoV-2 is the pathogen responsible for the most recent global pandemic, which has claimed hundreds of thousands of victims worldwide. Despite remarkable efforts to develop an effective vaccine, concerns have been raised about the actual protection against novel variants. Thus, researchers are eager to identify alternative strategies to fight against this pathogen. Like other opportunistic entities, a key step in the SARS-CoV-2 lifecycle is the maturation of the envelope glycoprotein at the RARR685↓ motif by the cellular enzyme Furin. Inhibition of this cleavage greatly affects viral propagation, thus representing an ideal drug target to contain infection. Importantly, no Furin-escape variants have ever been detected, suggesting that the pathogen cannot replace this protease by any means. Here, we designed a novel fluorogenic SARS-CoV-2-derived substrate to screen commercially available and custom-made libraries of small molecules for the identification of new Furin inhibitors. We found that a peptide substrate mimicking the cleavage site of the envelope glycoprotein of the Omicron variant (QTQTKSHRRAR-AMC) is a superior tool for screening Furin activity when compared to the commercially available Pyr-RTKR-AMC substrate. Using this setting, we identified promising novel compounds able to modulate Furin activity in vitro and suitable for interfering with SARS-CoV-2 maturation. In particular, we showed that 3-((5-((5-bromothiophen-2-yl)methylene)-4-oxo-4,5 dihydrothiazol-2-yl)(3-chloro-4-methylphenyl)amino)propanoic acid (P3, IC50 = 35 μM) may represent an attractive chemical scaffold for the development of more effective antiviral drugs via a mechanism of action that possibly implies the targeting of Furin secondary sites (exosites) rather than its canonical catalytic pocket. Overall, a SARS-CoV-2-derived peptide was investigated as a new substrate for in vitro high-throughput screening (HTS) of Furin inhibitors and allowed the identification of compound P3 as a promising hit with an innovative chemical scaffold. Given the key role of Furin in infection and the lack of any Food and Drug Administration (FDA)-approved Furin inhibitor, P3 represents an interesting antiviral candidate. [ABSTRACT FROM AUTHOR]

The taxonomic history, nomenclature and application of the oldest species names available for the common hybrids between Pilosella caespitosa and P. lactucella are reviewed. Elias Fries created a nomenclatural and bibliographical collision when he replaced a printed label of his exsiccata Herbarium normale with its second version, distributed at a later date, in which the protologue of Hieracium suecicum had appeared. In this protologue, the new species name was validly published with a mere reference to the original description of H. auricula var. majus, thus being based on the type of the latter. In a later fascicle of the same exsiccata, Fries excluded this synonym and distributed a different morphotype of H. suecicum, which caused taxonomic confusion and re-description of the same taxon under the name H. fennicum. The surviving original material of H. auricula var. majus is rejected, and its neotype is designated, making H. suecicum the correct name for the hybrids strictly intermediate between P. lactucella and P. caespitosa. Such hybrids constitute the most common hybridogenous taxon of Pilosella in Scandinavia, Finland and neighbouring Russia, with many synonyms described from this area and partly typified here. Another hybridogenous taxon of the same origin, more similar to P. lactucella and previously known as P. cochlearis, is correctly named P. stipitiflora comb. nov. The nomenclatural value and bibliographic complexity of exsiccata, a commonly underestimated kind of grey literature in taxonomic botany, are further highlighted. [ABSTRACT FROM AUTHOR]

This article focuses on the role of cross-cultural mediators in resolving conflicts related to cultural violence in Indonesia and provides an overview of the cultural context in Indonesia and the factors that contribute to the prevalence of cultural violence. The article then discusses the role of cross-cultural mediators in facilitating dialogue and promoting understanding between different cultural groups. Using a qualitative research methodology, the article explores the experiences of cross-cultural mediators working in different parts of Indonesia. Diverse references like literature, academic papers, scientific publications, dissertations, and similar materials concerning delicate cultural aspects, categorization of aggression within Indonesian society, and elements impacting the development of a violent culture are mentioned within the paper. The article highlights the challenges and opportunities that mediators face in their work, including the need to build trust and develop effective communication strategies. The article argues that cross-cultural mediation can be an effective tool for resolving conflicts related to cultural violence in Indonesia. The article emphasizes the importance of developing culturally sensitive and context-specific mediation strategies that take into account the unique cultural and historical factors that contribute to violence in different regions of the country. In conclusion, the article highlights the need for greater support for cross-cultural mediators in Indonesia, including training and capacity-building programs, as well as increased awareness and recognition of the important role that mediators play in promoting peace and resolving conflicts related to cultural violence. The article argues that cross-cultural mediation has the potential to contribute to building a more peaceful and just society. [ABSTRACT FROM AUTHOR]

Large animal contusion models of spinal cord injury are an essential precursor to developing and evaluating treatment options for human spinal cord injury. Reducing variability in these experiments has been a recent focus as it increases the sensitivity with which treatment effects can be detected while simultaneously decreasing the number of animals required in a study. Here, we conducted a detailed review to explore if head and neck positioning in a cervical contusion model of spinal cord injury could be a factor impacting the biomechanics of a spinal cord injury, and thus, the resulting outcomes. By reviewing existing literature, we found evidence that animal head/neck positioning a_ects the exposed level of the spinal cord, morphology of the spinal cord, tissue mechanics and as a result the biomechanics of a cervical spinal cord injury. We posited that neck position could be a hidden factor contributing to variability. Our results indicate that neck positioning is an important factor in studying biomechanics, and that reporting these values can improve inter-study consistency and comparability and that further work needs to be done to standardize positioning for cervical spinal cord contusion injury models. [ABSTRACT FROM AUTHOR]

Background: Libraries in the UK have evolved from traditional book-lending institutions into dynamic community hubs, This study aims to explore the potential of libraries to act as community hubs to promote mental and physical health and wellbeing of community-dwelling adults, drawing on insights from both library users and library staff in England. Design: A mixed-method, cross-sectional study using online survey and interviews with community-dwelling adults and library staff. Methods: We collected data using a 14-item electronic survey and interviews with library users and staff to gauge perceptions. Descriptive statistics and thematic analysis were used to identify key trends and emergent themes. Results: We included 605 respondents from the survey and interviewed 12 library users and staff. Libraries remain popular and are considered a 'safe place by members of the community, regardless of their frequency of service usage irrespective of whether they are frequent users of services. However, a lack of awareness among library users about community-facing services could act as a hurdle to improving community health and wellbeing. Targeted engagement with residents is needed to increase awareness of libraries' services, including community interventions to help tackle loneliness and inequalities in digital and health literacy. Library staff often did not feel involved in important decision-making. Various barriers, drivers and practical recommendations were identified to leverage libraries as hubs to promote community health and wellbeing. Conclusion: Libraries already offer a variety of resources that directly or indirectly support the health and wellbeing of community-dwelling adults and young people. However, public awareness of these services is limited. As we navigate post-pandemic recovery, libraries can serve as platforms for community engagement, fostering resilience, mental health support and reducing social isolation. Recognising libraries' untapped potential can lead to healthier communities and improved wellbeing. [ABSTRACT FROM AUTHOR]

The Ottoman Empire was established in the western neighboring Iran during the late 13th century and early 14th centuries. The relationship between the Ottoman Empire and Iran fluctuated between periods of peace and conflict. The migration of Iranian scholars to the Ottoman Empire is a significant aspect of the historical ties between These two country. One of these scholars was Mohammad ibn Mahmoud Shirvani who authored medical books and served different Ottoman rulers. He was born in the Shirvan region of Azerbaijan and later migrated to the Ottoman Empire. He served in the court of Sultan Mehmed II as one of the seven esteemed physicians. He continued to practice medicine and held the position of Chief Physician of Bayezid II before the year 889 AH. His works include pharmaceutical compilations like Revzat al-Atr fi’l-Tibb, ophthalmology works such as al-Murshid, and other medical compilations like Sultaniye and Yaqubiyye. These works indicate Shirvani’s extensive knowledge in various medical fields. Shirvani’s familiarity with the works of respected physicians like Avicenna and Ibn al-Baytar enriched his contributions to various medical fields. As an Iranian, he was able to draw from the works of other Iranian doctors written in Persian, benefiting from their insights. He made significant contributions to medical knowledge in the Ottoman civilization, as he facilitated the transmission of Iranian medical scholarship to the Ottoman Empire. Further research on his manuscripts and their comparison with medical texts from subsequent periods could yield valuable insights into his lasting impact on the field of medicine. [ABSTRACT FROM AUTHOR]

This article provides an account of the making of KBLab, the data lab at the National Library of Sweden (KB). The first part discusses the work involved in establishing a lab as both a physical and a digital site for researchers to use digital collections at previously unimaginable scales. The second part explains how the lab has deployed the library's collections as data to produce high quality Swedish AI models, which constitute a significant new form of digital research infrastructure. We situate this work in the context of uneven AI coverage for smaller languages, and consider how the lab's models have contributed to the making of important AI infrastructure for the Swedish language. The conclusion raises the possibilities and challenges involved in continuing this type of library-based AI development. [ABSTRACT FROM AUTHOR]

In 1524, Petrus Apianus published two closely related works—one the Latin Cosmographicus liber, aimed at an educated audience of international readers, and the other, Ein kunstlich Instrument, a shorter, more practical book for those who could read German but had no Latin. Both books nevertheless make use of most of the same instruments, including Apianus' early volvelles. Most of these instruments also reappear in subsequent editions of Cosmographicus liber (or Cosmographia, a frequent alternative title). While the Cosmographicus liber has received much scholarly attention, Ein kunstlich Instrument has received very little. In this paper we (1) set the instruments of Ein kunstlich Instrument in the context of Apianus' earlier work, especially his lost Mappa mundi and the extant booklets (Declaratio and Isagoge) that explained it, (2) compare the German- and Latin-language books of 1524, (3) explain in detail those instruments that have not heretofore been adequately discussed, and (4) explore their later history. We also make available, in the on-line edition of the Journal, working virtual copies of Apianus' instruments from Ein kunstlich Instrument. [ABSTRACT FROM AUTHOR]

Artistic pieces can be studied from several perspectives, one example being their reception among readers over time. In the present work, we approach this interesting topic from the standpoint of literary works, particularly assessing the task of predicting whether a book will become a best seller. Unlike previous approaches, we focused on the full content of books and considered visualization and classification tasks. We employed visualization for the preliminary exploration of the data structure and properties, involving SemAxis and linear discriminant analyses. To obtain quantitative and more objective results, we employed various classifiers. Such approaches were used along with a dataset containing (i) books published from 1895 to 1923 and consecrated as best sellers by the Publishers Weekly Bestseller Lists and (ii) literary works published in the same period but not being mentioned in that list. Our comparison of methods revealed that the best-achieved result—combining a bag-of-words representation with a logistic regression classifier—led to an average accuracy of 0.75 both for the leave-one-out and 10-fold cross-validations. Such an outcome enhances the difficulty in predicting the success of books with high accuracy, even using the full content of the texts. Nevertheless, our findings provide insights into the factors leading to the relative success of a literary work. [ABSTRACT FROM AUTHOR]

Epidermal growth factor receptor EGFR inhibitors are widely used as first line therapy for the treatment of non-small-cell lung cancer (NSCLC) in patients harboring EGFR mutation. However, the acquisition of a second-site mutation (T790 M) limited the efficacy and developed resistance. Therefore, discovery and development of specific drug target for this mutation is of urgent needs. In our study we used the ChemDiv diversity database for receptor-based virtual screening to secure EGFR-TK inhibitors chemotherapeutics. We identified four compounds that bind to the ATP-binding region of the EGFR-TK using AutoDock 4.0 and AutoDock Vina1.1.2 and post-docking investigations. The ligand showed hydrophobic interactions to the hydrophobic region of the binding site and engaged in hydrogen bonding with Met793. The ligands also explored π–cation interactions between the π-system of the ligand–phenyl ring and the positive amino group of Lys745. Molecular mechanics Poisson–Boltzmann surface area MM/PBSA per-residue energy decomposition analyses revealed that Val726, Leu792, Met793, Gly796, Cys797, Leu798, and Thr844 contributed the most to the binding energy. Biological evaluation of the retrieved hit compounds showed suppressing activity against EGFR auto phosphorylation and selective apoptosis-induced effects toward lung cancer cells harboring the EGFR L858R/T790M double mutation. Our work anticipated into novel and specific EGFR-TKIs and identified new compounds with therapeutic potential against lung cancer. [ABSTRACT FROM AUTHOR]

The research aims to determine the process of digitizing the gray literature collection carried out by the Bandung Djunjunan National Research and Innovation Agency Library. A descriptive qualitative method is used in this research. Data were collected through observation, interviews, and literature review. There were three informants in this study. Data analysis through data condensation, data presentation, and drawing conclusions. The research results show that the digitization of the gray literature collection was carried out as an effort to preserve and disseminate the information contained in the collection. The stages of digitizing the collection are preparation, digitization process, editing and validation process, as well as the upload process to Repokarya. The gray literature collection that has been digitized is not stored in the library but is handed over to BRIN's BMN (State Property Services) service. The obstacles in implementing digitalization are limited facilities and infrastructure as well as human resources. [ABSTRACT FROM AUTHOR]

Today's technology is growing rapidly, considering quality and quantity, this case explains the role of the library. Libraries must be able to adjust to the needs of users quickly and effectively, therefore libraries are required to be at least dexterous in using technology. In terms of digital literacy, librarians must be able to understand and use various sources of information and digital media to meet the needs of people's lives. The development of an "Open Library " can be based on how to develop library-based information technology to continue to improve library services, collections, and databases. Open Library is a facility that can be used by the academic community of Telkom University and the general public. Therefore, this study is based on the optimization of the use of the Open Library Application Telkom University of Bandung, and in this case study was conducted directly in the library to see the extent to which this application is used optimally and used several ways of collecting data. One of them interviews with sources in the library. [ABSTRACT FROM AUTHOR]

This research is motivated by an interesting phenomenon of changing times marked by the mushrooming use of information technology that makes the Library able to provide all services quickly, precisely, accurately, anytime, and anywhere. And, in real-time these services can be utilized by users, namely the use of e-library applications applied at the UIN Raden Fatah Library is very interesting to be researched. This research is quantitative, and data were collected by using applications from the Library Science students of class 2020. To see the use of the application, researchers use the theory of total quality management (TQM) which is reviewed through 4 principles, namely the principles of user satisfaction, respect for users, management in line with facts, and continuous improvement. Of the four principles, the survey results are above the average of 50%, meaning that each indicator in each principle has good service quality such as a comfortable application interface, user-friendly application use, good and satisfactory e-library service quality, adequate collection, and can meet user needs. Library efforts that continuously add to existing collections in the e-library application are updated to the latest version. There is a huge need to socialize the use of the application and promotional activities for the application to continue to be carried out. The research data shows that the survey results 75% on average, have gone well. Based on the results of this simple research, all principles in TQM have achieved excellent scores, this is shown by the average acquisition of survey numbers above 50%. [ABSTRACT FROM AUTHOR]

Purpose: This study aims to determine the extent of virtual reality (VR)/augmented reality (AR) adoption in university libraries in Indonesia and identify librarians' views of library readiness. The assessment centers on two crucial dimensions: library readiness, gauged by commitment and efficacy, and librarian readiness, appraised through cognitive and affective aspects. Design/methodology/approach: The research features a survey-based quantitative method. A sample of 259 librarians from university libraries, all members of the Indonesian Higher Education Library Forum, responded to the online survey. Findings: Indonesian university libraries, especially in Central Java, express strong interest in VR/AR despite low current adoption. Librarians believe in their commitment and efficacy for adoption, with improvements needed in budget procurement and human resources. Librarians are optimistic about innovating academic activities with VR/AR, despite concerns about collaboration, data governance and human resource insecurity. The research underscores the simultaneous influence of librarians' and libraries' readiness on VR/AR adoption, emphasizing their interconnectedness and mutual support within library management. Practical implications: There are practical implications for library institutions in Indonesia in terms of understanding the attendant opportunities and challenges when preparing organizational ecosystems. These findings provide a broad overview of VR/AR adoption in university libraries in Indonesia and contribute to understanding the specific needs and interests of universities in Indonesia considering adopting VR/AR. In addition to preparing adequate infrastructure, libraries should ensure the availability of adequate human resources. Originality/value: In the Indonesian context, this study, to the best of the authors' knowledge, makes the first attempt to examine the librarian's view as part of library management to face the dilemmas that may arise during the adoption of VR/AR despite university libraries' commitment and efficacy to enable this technology. This research also identifies librarians' cognitive and affective readiness as individual characteristics and resources able to influence adequate adoption. [ABSTRACT FROM AUTHOR]

To help address the well-being of the campus and contribute to empathy building amongst students pursuing careers as healthcare providers, an academic health sciences library built a graphic novel collection focused on comics that discuss medical conditions and health-related topics. The collection contains the experiences of patients, providers, and caregivers. The reader-friendly format of graphic novels provides an easy entry point for discussing empathy with health professions faculty and students. The collection has been used in the classroom during library instruction sessions, with the idea of integrating it within the curriculum. [ABSTRACT FROM AUTHOR]

The purpose of this study was to investigate the relationship between the use of technology and the development of research skills in future teachers, specifically current graduate students participating in Mathematical Olympiads. The study used a quantitative approach and analyzed data collected through a survey. The findings indicated that quantitative analysis skills, problem-solving skills, communication skills, and research methodology skills are the dimensions of research skills in future teachers. The results showed that the use of digital tools for literature searching and curation, online courses and workshops (OCWs), collaborative learning and discussion forums, and data analysis software significantly and positively affected research skills. However, the study failed to provide evidence that digital portfolios (DPs) affected research skills. The limitations of the study and recommendations for future research are discussed. In conclusion, the findings highlight the importance of technology in the development of research skills in future teachers and suggest that technology-based learning resources and tools should be integrated into teacher training programs. [ABSTRACT FROM AUTHOR]

This paper explores the potential of the Mass Observation Archive at the University of Sussex for studying the history of Methodism in Bolton (aka 'Worktown') during the middle third of the twentieth century, with particular reference to the years 1937–40 and 1960, demonstrating its value for recording the lived experience of Methodism. An appendix contains three key documents, two of them relating to the work of the Victoria Hall in the Bolton Mission circuit, which was much lauded by Mass Observation. [ABSTRACT FROM AUTHOR]

Digitisation has become an essential part of archival and library strategies to enhance access to collections. As the digital content is increasing due to large-scale digitisation projects, it is expected that providing digital access to the analogue collections will eventually reduce the number of archival records accessed in the reading room. In this paper, we investigate this issue using two approaches: system dynamics and agent-based modelling. We first analyse real data in order to identify the dynamic hypothesis of the model. Then, a sensitivity analysis is conducted on two baseline models to identify scenarios that match the real dataset. Although the two approaches suceed to simulate the number of requests in the reading room, the experimental results show that a better fit is obtained in the agent-based model when not only the number of records that have been accessed and digitised is taken into account, but also the number of times that such records have been accessed before digitisation. The proposed model can be used to explore the impact of different digitisation strategies on the decrease in access requests in the archival and library reading rooms. [ABSTRACT FROM AUTHOR]

This document is a list of references for a research paper on various topics related to mental health, artificial intelligence, and data analysis. The references cover studies on loneliness and mental health during the COVID-19 pandemic, risk factors for suicidal thoughts and behaviors, medical big data, machine learning techniques, and the use of artificial intelligence in mental health research. The document also includes resources on the validation and accuracy of diagnoses, classification of psychiatric disorders, and the challenges and opportunities of data sharing in mental health research. [Extracted from the article]

Chronic obstructive pulmonary disease (COPD) is often part of a more complex cardiopulmonary disease, especially in older patients. The differential diagnosis of the acute exacerbation of COPD and/or heart failure (HF) in emergency settings is challenging due to their frequent coexistence and symptom overlap. Both conditions have a detrimental impact on each other's prognosis, leading to increased mortality rates. The timely diagnosis and treatment of COPD and coexisting factors like left ventricular overload or HF in inpatient and outpatient care can improve prognosis, quality of life, and long-term outcomes, helping to avoid exacerbations and hospitalization, which increase future exacerbation risk. This work aims to address existing gaps, providing management recommendations for COPD with/without HF, particularly when both conditions coexist. During virtual meetings, a panel of experts (the authors) discussed and reached a consensus on the differential and paired diagnosis of COPD and HF, providing suggestions for risk stratification, accurate diagnosis, and appropriate therapy for inpatients and outpatients. They emphasize that when COPD and HF are concomitant, both conditions should receive adequate treatment and that recommended HF treatments are not contraindicated in COPD and have favorable effects. Accurate diagnosis and therapy is crucial for effective treatment, reducing hospital readmissions and associated costs. The management considerations discussed in this study can potentially be extended to address other cardiopulmonary challenges frequently encountered by COPD patients. [ABSTRACT FROM AUTHOR]

Background: Many people who face adversity, such as disasters, demonstrate resilience. However, less is known about reactions to large scale disasters with longer recovery periods. The concern is that protracted disasters may result in more chronic or accumulated stressors with an uncertain or unknown end point and can exhaust the natural coping methods and ability to rebound. Thus, understanding patterns of longer-term disaster recovery, inclusive of resilience, is needed. Further resilience is not individual specific rather social determinants, such as support networks and available resources, are contributing factors. Methods: The purpose of this study is to improve understanding of mental health and resilience during increased stress, we aim to identify profiles of adaptation and psychological and social determinants that predict membership within predominant symptom groupings. We conducted an exploratory crosssection study (N = 334) with two phases of multivariate analysis. Latent profile models were estimated to identify groups based on depression, anxiety, and resilience scores. The second phase included a step-wise multinomial logistic regression to predict class membership. Results: We identified four distinct groups: 33% of participants were categorized as anxious, 18% depressed, 9% comorbid, and 40% with above average levels of resilience. Psychosocial factors such as demographics, trauma history, information access, loneliness, and lack of financial resources predicted poorer mental health outcomes and lower resilience. Conclusion: This study identified factors that contribute to overall wellbeing despite chronic stressors. Social determinants of adaptation, found in this study population, include loneliness, finances, and information access. The findings from this study support the need for both psychological and social adaption supports, inclusive of mental health treatment, to strengthen resilience activation. [ABSTRACT FROM AUTHOR]

Calpains are cysteine proteases that control cell fate transitions whose loss of function causes severe, pleiotropic phenotypes in eukaryotes. Although mainly considered as modulatory proteases, human calpain targets are directed to the N-end rule degradation pathway. Several such targets are transcription factors, hinting at a gene-regulatory role. Here, we analyze the gene-regulatory networks of the moss Physcomitrium patens and characterize the regulons that are misregulated in mutants of the calpain DEFECTIVE KERNEL1 (DEK1). Predicted cleavage patterns of the regulatory hierarchies in five DEK1-controlled subnetworks are consistent with a pleiotropic and regulatory role during cell fate transitions targeting multiple functions. Network structure suggests DEK1-gated sequential transitions between cell fates in 2D-to-3D development. Our method combines comprehensive phenotyping, transcriptomics and data science to dissect phenotypic traits, and our model explains the protease function as a switch gatekeeping cell fate transitions potentially also beyond plant development. Examination of the cell fate gene-regulatory networks of the moss Physcomitrium patens reveals regulons that exhibit misregulation in mutants for the calpain DEFECTIVE KERNEL1 (DEK1) gene. [ABSTRACT FROM AUTHOR]

The article discusses the experiences of Afro-Caribbean laborers who traveled to Panama to work on the construction of the Panama Canal from 1904 to 1914. These workers left their homes in various Caribbean islands and faced difficult conditions and discrimination while working on the canal. The article highlights the importance of their contributions to the construction of the canal and the lasting impact they had on the Americas. The testimonies of these workers, collected in a competition organized by the Isthmian Historical Society, provide valuable insights into their experiences and challenges. [Extracted from the article]

This document provides a comprehensive list of selected full-text databases for research in East Asian Studies. The databases cover a wide range of topics including history, literature, language, culture, and more. They offer access to primary source materials, dissertations, theses, ebooks, yearbooks, statistical data, and other valuable resources. The databases are available in multiple languages and provide diverse perspectives on East Asian subjects. These resources are valuable for library patrons conducting research in a culturally sensitive manner. [Extracted from the article]

The San Francisco Estuary (estuary) and the Sacramento-San Joaquin Delta (the Delta) in California face significant challenges in managing water resources during extended droughts. Zooplankton are a vital trophic link between phytoplankton producers and higherlevel consumers such as predatory zooplankton and fish. However, there is still much to be learned about what drives zooplankton abundance and how they respond to drastic changes in environmental conditions, such as droughts. We found that during drought years zooplankton abundance and distribution changes varied for examined taxa. Significant declines in the abundance of Daphnia spp. and the copepod Pseudodiaptomus forbesi occurred in the Suisun Marsh and Suisun Bay regions. In contrast, abundance of the non-native copepod Limnoithona tetraspina increased in Suisun Marsh and the South-Central Delta during those same drought conditions. Salinity is a strong determinant of the presence and abundance of the studied taxa, and we showed that changes in the distribution of salinity as a result of low outflow conditions were an important factor in the regional abundance of zooplankton. Because of the expected increase in the frequency and severity of regional droughts, understanding how these conditions affect zooplankton in the estuary will benefit scientists and resource managers who aim to improve conditions for native fishes. [ABSTRACT FROM AUTHOR]