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Simple Summary: Breast cancer is a significant cause of female cancer-related deaths in the US. Checking how severe the cancer is helps in planning treatment. Modern AI methods are good at grading cancer, but they are not used much in hospitals yet. We developed and utilized ensemble deep learning algorithms for addressing the tasks of classifying (1) breast cancer subtype and (2) breast cancer invasiveness from whole slide image (WSI) histopathology slides. The ensemble models used were based on convolutional neural networks (CNNs) known for extracting distinctive features crucial for accurate classification. In this paper, we provide a comprehensive analysis of these models and the used methodology for breast cancer diagnosis tasks. Cancer diagnosis and classification are pivotal for effective patient management and treatment planning. In this study, a comprehensive approach is presented utilizing ensemble deep learning techniques to analyze breast cancer histopathology images. Our datasets were based on two widely employed datasets from different centers for two different tasks: BACH and BreakHis. Within the BACH dataset, a proposed ensemble strategy was employed, incorporating VGG16 and ResNet50 architectures to achieve precise classification of breast cancer histopathology images. Introducing a novel image patching technique to preprocess a high-resolution image facilitated a focused analysis of localized regions of interest. The annotated BACH dataset encompassed 400 WSIs across four distinct classes: Normal, Benign, In Situ Carcinoma, and Invasive Carcinoma. In addition, the proposed ensemble was used on the BreakHis dataset, utilizing VGG16, ResNet34, and ResNet50 models to classify microscopic images into eight distinct categories (four benign and four malignant). For both datasets, a five-fold cross-validation approach was employed for rigorous training and testing. Preliminary experimental results indicated a patch classification accuracy of 95.31% (for the BACH dataset) and WSI image classification accuracy of 98.43% (BreakHis). This research significantly contributes to ongoing endeavors in harnessing artificial intelligence to advance breast cancer diagnosis, potentially fostering improved patient outcomes and alleviating healthcare burdens. [ABSTRACT FROM AUTHOR]

Deep learning techniques have recently yielded remarkable results across various fields. However, the quality of these results depends heavily on the quality and quantity of data used during the training phase. One common issue in multi-class and multi-label classification is class imbalance, where one or several classes make up a substantial portion of the total instances. This imbalance causes the neural network to prioritize features of the majority classes during training, as their detection leads to higher scores. In the context of object detection, two types of imbalance can be identified: (1) an imbalance between the space occupied by the foreground and background and (2) an imbalance in the number of instances for each class. This paper aims to address the second type of imbalance without exacerbating the first. To achieve this, we propose a modification of the copy-paste data augmentation technique, combined with weight-balancing methods in the loss function. This strategy was specifically tailored to improve the performance in datasets with a high instance density, where instance overlap could be detrimental. To validate our methodology, we applied it to a highly unbalanced dataset focused on nuclei detection. The results show that this hybrid approach improves the classification of minority classes without significantly compromising the performance of majority classes. [ABSTRACT FROM AUTHOR]

In recent times, there has been considerable focus on harnessing artificial intelligence (AI) for medical image analysis and healthcare purposes. In this study, we introduce CADFU (Computer-Aided Diagnosis System for Foot Ulcers), a pioneering diabetic foot ulcer diagnosis system. The primary objective of CADFU is to detect and segment ulcers and similar chronic wounds in medical images. To achieve this, we employ two distinct algorithms. Firstly, DHuNeT, an innovative Dual-Phase Hyperactive UNet, is utilized for the segmentation task. Second, we used YOLOv8 for the task of detecting wounds. The DHuNeT autoencoder, employed for the wound segmentation task, is the paper's primary and most significant contribution. DHuNeT is the combination of sequentially stacking two UNet autoencoders. The hyperactive information transmission from the first UNet to the second UNet is the key idea of DHuNeT. The first UNet feeds the second UNet the features it has learned, and the two UNets combine their learned features to create new, more accurate, and effective features. We achieve good performance measures, especially in terms of the Dice co-efficient and precision, with segmentation scores of 85% and 92.6%, respectively. We obtain a mean average precision (mAP) of 86% in the detection task. Future hospitals could quickly monitor patients' health using the proposed CADFU system, which would be beneficial for both patients and doctors. [ABSTRACT FROM AUTHOR]

Simple Summary: Accurately grading gliomas, which are the most common and aggressive malignant brain tumors in adults, poses a significant challenge for radiologists. This study explores the application of Deep Learning techniques in assisting tumor grading using Magnetic Resonance Images (MRIs). By analyzing a glioma database sourced from multiple public datasets and comparing different settings, the aim of this study is to develop a robust and reliable grading system. The study demonstrates that by focusing on the tumor region of interest and augmenting the available data, there is a significant improvement in both the accuracy and confidence of tumor grade classifications. While successful in differentiating low-grade gliomas from high-grade gliomas, the accurate classification of grades 2, 3, and 4 remains challenging. The research findings have significant implications for advancing the development of a non-invasive, robust, and trustworthy data-driven system to support clinicians in the diagnosis and therapy planning of glioma patients. Glioma is the most common type of tumor in humans originating in the brain. According to the World Health Organization, gliomas can be graded on a four-stage scale, ranging from the most benign to the most malignant. The grading of these tumors from image information is a far from trivial task for radiologists and one in which they could be assisted by machine-learning-based decision support. However, the machine learning analytical pipeline is also fraught with perils stemming from different sources, such as inadvertent data leakage, adequacy of 2D image sampling, or classifier assessment biases. In this paper, we analyze a glioma database sourced from multiple datasets using a simple classifier, aiming to obtain a reliable tumor grading and, on the way, we provide a few guidelines to ensure such reliability. Our results reveal that by focusing on the tumor region of interest and using data augmentation techniques we significantly enhanced the accuracy and confidence in tumor classifications. Evaluation on an independent test set resulted in an AUC-ROC of 0.932 in the discrimination of low-grade gliomas from high-grade gliomas, and an AUC-ROC of 0.893 in the classification of grades 2, 3, and 4. The study also highlights the importance of providing, beyond generic classification performance, measures of how reliable and trustworthy the model's output is, thus assessing the model's certainty and robustness. [ABSTRACT FROM AUTHOR]

We present a deep learning-based method that corrects motion artifacts and thus accelerates data acquisition and reconstruction of magnetic resonance images. The novel model, the Motion Artifact Correction by Swin Network (MACS-Net), uses a Swin transformer layer as the fundamental block and the Unet architecture as the neural network backbone. We employ a hierarchical transformer with shifted windows to extract multiscale contextual features during encoding. A new dual upsampling technique is employed to enhance the spatial resolutions of feature maps in the Swin transformer-based decoder layer. A raw magnetic resonance imaging dataset is used for network training and testing; the data contain various motion artifacts with ground truth images of the same subjects. The results were compared to six state-of-the-art MRI image motion correction methods using two types of motions. When motions were brief (within 5 s), the method reduced the average normalized root mean square error (NRMSE) from 45.25% to 17.51%, increased the mean structural similarity index measure (SSIM) from 79.43% to 91.72%, and increased the peak signal-to-noise ratio (PSNR) from 18.24 to 26.57 dB. Similarly, when motions were extended from 5 to 10 s, our approach decreased the average NRMSE from 60.30% to 21.04%, improved the mean SSIM from 33.86% to 90.33%, and increased the PSNR from 15.64 to 24.99 dB. The anatomical structures of the corrected images and the motion-free brain data were similar. [ABSTRACT FROM AUTHOR]

The identification and characterization of lung diseases is one of the most interesting research topics in recent years. They require accurate and rapid diagnosis. Although lung imaging techniques have many advantages for disease diagnosis, the interpretation of medial lung images has always been a major problem for physicians and radiologists due to diagnostic errors. This has encouraged the use of modern artificial intelligence techniques such as deep learning. In this paper, a deep learning architecture based on EfficientNetB7, known as the most advanced architecture among convolutional networks, has been constructed for classification of medical X-ray and CT images of lungs into three classes namely: common pneumonia, coronavirus pneumonia and normal cases. In terms of accuracy, the proposed model is compared with recent pneumonia detection techniques. The results provided robust and consistent features to this system for pneumonia detection with predictive accuracy according to the three classes mentioned above for both imaging modalities: radiography at 99.81% and CT at 99.88%. This work implements an accurate computer-aided system for the analysis of radiographic and CT medical images. The results of the classification are promising and will certainly improve the diagnosis and decision making of lung diseases that keep appearing over time. [ABSTRACT FROM AUTHOR]

Simple Summary: Artificial intelligence techniques have changed the traditional way of diagnosis. The physicians' consultation decisions can now be supported with a particular algorithm that is beneficial for the patient in terms of accuracy and time saved. Many deep learning and machine learning algorithms are being validated and tested regularly; still, only a few can be implemented clinically. This review aims to shed light on the current and potential applications of deep learning and machine learning in tumor pathology. The revolution of artificial intelligence and its impacts on our daily life has led to tremendous interest in the field and its related subtypes: machine learning and deep learning. Scientists and developers have designed machine learning- and deep learning-based algorithms to perform various tasks related to tumor pathologies, such as tumor detection, classification, grading with variant stages, diagnostic forecasting, recognition of pathological attributes, pathogenesis, and genomic mutations. Pathologists are interested in artificial intelligence to improve the diagnosis precision impartiality and to minimize the workload combined with the time consumed, which affects the accuracy of the decision taken. Regrettably, there are already certain obstacles to overcome connected to artificial intelligence deployments, such as the applicability and validation of algorithms and computational technologies, in addition to the ability to train pathologists and doctors to use these machines and their willingness to accept the results. This review paper provides a survey of how machine learning and deep learning methods could be implemented into health care providers' routine tasks and the obstacles and opportunities for artificial intelligence application in tumor morphology. [ABSTRACT FROM AUTHOR]

Simple Summary: The Internet of Things (IoT) uses connected devices and sensors, like high-resolution cameras and specific sensors in wearable devices, for the collection of skin images with abnormalities. Skin cancer detection is difficult because of differences in lesion size, shape, and lighting conditions. To address this, an innovative approach called "ODL-SCDC", combining deep learning with IoT technology, is developed. The proposed model uses advanced techniques like hyperparameter selection and feature extraction to improve skin cancer classification. The results show that ODL-SCDC outperforms other methods in accurately identifying skin lesions, which could have a significant impact on early cancer detection in the medical field. Internet of Things (IoT)-assisted skin cancer recognition integrates several connected devices and sensors for supporting the primary analysis and monitoring of skin conditions. A preliminary analysis of skin cancer images is extremely difficult because of factors such as distinct sizes and shapes of lesions, differences in color illumination, and light reflections on the skin surface. In recent times, IoT-based skin cancer recognition utilizing deep learning (DL) has been used for enhancing the early analysis and monitoring of skin cancer. This article presents an optimal deep learning-based skin cancer detection and classification (ODL-SCDC) methodology in the IoT environment. The goal of the ODL-SCDC technique is to exploit metaheuristic-based hyperparameter selection approaches with a DL model for skin cancer classification. The ODL-SCDC methodology involves an arithmetic optimization algorithm (AOA) with the EfficientNet model for feature extraction. For skin cancer detection, a stacked denoising autoencoder (SDAE) classification model has been used. Lastly, the dragonfly algorithm (DFA) is utilized for the optimal hyperparameter selection of the SDAE algorithm. The simulation validation of the ODL-SCDC methodology has been tested on a benchmark ISIC skin lesion database. The extensive outcomes reported a better solution of the ODL-SCDC methodology compared with other models, with a maximum sensitivity of 97.74%, specificity of 99.71%, and accuracy of 99.55%. The proposed model can assist medical professionals, specifically dermatologists and potentially other healthcare practitioners, in the skin cancer diagnosis process. [ABSTRACT FROM AUTHOR]

Abdominal ultrasonography has become an integral component of the evaluation of trauma patients. Internal hemorrhage can be rapidly diagnosed by finding free fluid with point-of-care ultrasound (POCUS) and expedite decisions to perform lifesaving interventions. However, the widespread clinical application of ultrasound is limited by the expertise required for image interpretation. This study aimed to develop a deep learning algorithm to identify the presence and location of hemoperitoneum on POCUS to assist novice clinicians in accurate interpretation of the Focused Assessment with Sonography in Trauma (FAST) exam. We analyzed right upper quadrant (RUQ) FAST exams obtained from 94 adult patients (44 confirmed hemoperitoneum) using the YoloV3 object detection algorithm. Exams were partitioned via fivefold stratified sampling for training, validation, and hold-out testing. We assessed each exam image-by-image using YoloV3 and determined hemoperitoneum presence for the exam using the detection with highest confidence score. We determined the detection threshold as the score that maximizes the geometric mean of sensitivity and specificity over the validation set. The algorithm had 95% sensitivity, 94% specificity, 95% accuracy, and 97% AUC over the test set, significantly outperforming three recent methods. The algorithm also exhibited strength in localization, while the detected box sizes varied with a 56% IOU averaged over positive cases. Image processing demonstrated only 57-ms latency, which is adequate for real-time use at the bedside. These results suggest that a deep learning algorithm can rapidly and accurately identify the presence and location of free fluid in the RUQ of the FAST exam in adult patients with hemoperitoneum. [ABSTRACT FROM AUTHOR]

The purpose of this study is to explore how machine learning technologies can improve healthcare operations management. A machine learning-based model to solve a specific medical problem is developed to achieve this research purpose. Specifically, this study presents an AI solution for malaria infection diagnosis by applying the CNN (convolutional neural network) algorithm. Based on malaria microscopy image data from the NIH National Library of Medicine, a total of 24,958 images were used for deep learning training, and 2600 images were selected for final testing of the proposed diagnostic architecture. The empirical results indicate that the CNN diagnostic model correctly classified most malaria-infected and non-infected cases with minimal misclassification, with performance metrics of precision (0.97), recall (0.99), and f1-score (0.98) for uninfected cells, and precision (0.99), recall (0.97), and f1-score (0.98) for parasite cells. The CNN diagnostic solution rapidly processed a large number of cases with a high reliable accuracy of 97.81%. The performance of this CNN model was further validated through the k-fold cross-validation test. These results suggest the advantage of machine learning-based diagnostic methods over conventional manual diagnostic methods in improving healthcare operational capabilities in terms of diagnostic quality, processing costs, lead time, and productivity. In addition, a machine learning diagnosis system is more likely to enhance the financial profitability of healthcare operations by reducing the risk of unnecessary medical disputes related to diagnostic errors. As an extension for future research, propositions with a research framework are presented to examine the impacts of machine learning on healthcare operations management for safety and quality of life in global communities. [ABSTRACT FROM AUTHOR]

Simple Summary: While deep learning has become a powerful tool in analysis of cancer imaging, deep learning models have potential vulnerabilities that pose security threats in the setting of clinical implementation. One weakness of deep learning models is that they can be deceived by adversarial images, which are manipulated images that have pixels intentionally perturbed to alter the output of the deep learning model. Recent research has shown that adversarial detection models can differentiate adversarial images from normal images to protect deep learning models from attack. We compared the effectiveness of different adversarial detection schemes, using three cancer imaging datasets (computed tomography, mammography, and magnetic resonance imaging). We found that that the detection schemes demonstrate strong performance overall but exhibit limited efficacy in detecting a subset of adversarial images. We believe our findings provide a useful basis in the application of adversarial defenses to deep learning models for medical images in oncology. Deep learning (DL) models have demonstrated state-of-the-art performance in the classification of diagnostic imaging in oncology. However, DL models for medical images can be compromised by adversarial images, where pixel values of input images are manipulated to deceive the DL model. To address this limitation, our study investigates the detectability of adversarial images in oncology using multiple detection schemes. Experiments were conducted on thoracic computed tomography (CT) scans, mammography, and brain magnetic resonance imaging (MRI). For each dataset we trained a convolutional neural network to classify the presence or absence of malignancy. We trained five DL and machine learning (ML)-based detection models and tested their performance in detecting adversarial images. Adversarial images generated using projected gradient descent (PGD) with a perturbation size of 0.004 were detected by the ResNet detection model with an accuracy of 100% for CT, 100% for mammogram, and 90.0% for MRI. Overall, adversarial images were detected with high accuracy in settings where adversarial perturbation was above set thresholds. Adversarial detection should be considered alongside adversarial training as a defense technique to protect DL models for cancer imaging classification from the threat of adversarial images. [ABSTRACT FROM AUTHOR]

Prostate cancer (PCa) is becoming one of the most frequently occurring cancers among men and causes an even greater number of deaths. Due to the complexity of tumor masses, radiologists find it difficult to identify PCa accurately. Over the years, several PCa-detecting methods have been formulated, but these methods cannot identify cancer efficiently. Artificial Intelligence (AI) has both information technologies that simulate natural or biological phenomena and human intelligence in addressing issues. AI technologies have been broadly implemented in the healthcare domain, including 3D printing, disease diagnosis, health monitoring, hospital scheduling, clinical decision support, classification and prediction, and medical data analysis. These applications significantly boost the cost-effectiveness and accuracy of healthcare services. This article introduces an Archimedes Optimization Algorithm with Deep Learning-based Prostate Cancer Classification (AOADLB-P2C) model on MRI images. The presented AOADLB-P2C model examines MRI images for the identification of PCa. To accomplish this, the AOADLB-P2C model performs pre-processing in two stages: adaptive median filtering (AMF)-based noise removal and contrast enhancement. Additionally, the presented AOADLB-P2C model extracts features via a densely connected network (DenseNet-161) model with a root-mean-square propagation (RMSProp) optimizer. Finally, the presented AOADLB-P2C model classifies PCa using the AOA with a least-squares support vector machine (LS-SVM) method. The simulation values of the presented AOADLB-P2C model are tested using a benchmark MRI dataset. The comparative experimental results demonstrate the improvements of the AOADLB-P2C model over other recent approaches. [ABSTRACT FROM AUTHOR]

Simple Summary: This study proposed the "Residual-Dense-Attention" (RDA) U-Net model architecture to automatically segment organs and lesions in computed tomography (CT) images. The RDA U-Net used ResBlock and DenseBlock at the encoder. Attention gates were used at the decoder position to help the model suppress irrelevant areas of the CT image. Forty-one patients' bladder images were provided for training. The RDA U-Net provided faster but satisfactory segmentation results for bladder cancers and lesions. In today's high-order health examination, imaging examination accounts for a large proportion. Computed tomography (CT), which can detect the whole body, uses X-rays to penetrate the human body to obtain images. Its presentation is a high-resolution black-and-white image composed of gray scales. It is expected to assist doctors in making judgments through deep learning based on the image recognition technology of artificial intelligence. It used CT images to identify the bladder and lesions and then segmented them in the images. The images can achieve high accuracy without using a developer. In this study, the U-Net neural network, commonly used in the medical field, was used to extend the encoder position in combination with the ResBlock in ResNet and the Dense Block in DenseNet, so that the training could maintain the training parameters while reducing the overall identification operation time. The decoder could be used in combination with Attention Gates to suppress the irrelevant areas of the image while paying attention to significant features. Combined with the above algorithm, we proposed a Residual-Dense Attention (RDA) U-Net model, which was used to identify organs and lesions from CT images of abdominal scans. The accuracy (ACC) of using this model for the bladder and its lesions was 96% and 93%, respectively. The values of Intersection over Union (IoU) were 0.9505 and 0.8024, respectively. Average Hausdorff distance (AVGDIST) was as low as 0.02 and 0.12, respectively, and the overall training time was reduced by up to 44% compared with other convolution neural networks. [ABSTRACT FROM AUTHOR]

This study addresses the problem of the automatic detection of disease states of the retina. In order to solve the abovementioned problem, this study develops an artificially intelligent model. The model is based on a customized 19-layer deep convolutional neural network called VGG-19 architecture. The model (VGG-19 architecture) is empowered by transfer learning. The model is designed so that it can learn from a large set of images taken with optical coherence tomography (OCT) and classify them into four conditions of the retina: (1) choroidal neovascularization, (2) drusen, (3) diabetic macular edema, and (4) normal form. The training datasets (taken from publicly available sources) consist of 84,568 instances of OCT retinal images. The datasets exhibit all four classes of retinal disease mentioned above. The proposed model achieved a 99.17% classification accuracy with 0.995 specificities and 0.99 sensitivity, making it better than the existing models. In addition, the proper statistical evaluation is done on the predictions using such performance measures as (1) area under the receiver operating characteristic curve, (2) Cohen's kappa parameter, and (3) confusion matrix. Experimental results show that the proposed VGG-19 architecture coupled with transfer learning is an effective technique for automatically detecting the disease state of a retina. [ABSTRACT FROM AUTHOR]

Simple Summary: Inducible T-cell COStimulator (ICOS) is a biomarker of interest in checkpoint inhibitor therapy, and as a means of assessing T-cell regulation as part of a complex process of adaptive immunity. The aim of our study is to segment the ICOS positive cells using a lightweight deep-learning segmentation network. We aim to assess the potential of a convolutional neural network and transformer together that permits the capture of relevant features from immunohistochemistry images. The proposed study achieved remarkable results compared to the existing biomedical segmentation methods on our in-house dataset and surpassed our previous analysis by only utilizing the Efficient-UNet network. In this article, we propose ICOSeg, a lightweight deep learning model that accurately segments the immune-checkpoint biomarker, Inducible T-cell COStimulator (ICOS) protein in colon cancer from immunohistochemistry (IHC) slide patches. The proposed model relies on the MobileViT network that includes two main components: convolutional neural network (CNN) layers for extracting spatial features; and a transformer block for capturing a global feature representation from IHC patch images. The ICOSeg uses an encoder and decoder sub-network. The encoder extracts the positive cell's salient features (i.e., shape, texture, intensity, and margin), and the decoder reconstructs important features into segmentation maps. To improve the model generalization capabilities, we adopted a channel attention mechanism that added to the bottleneck of the encoder layer. This approach highlighted the most relevant cell structures by discriminating between the targeted cell and background tissues. We performed extensive experiments on our in-house dataset. The experimental results confirm that the proposed model achieves more significant results against state-of-the-art methods, together with an 8× reduction in parameters. [ABSTRACT FROM AUTHOR]

Simple Summary: The rapid development of technology has enabled numerous applications of artificial intelligence (AI), especially in medical science. Histopathological assessment of tissues remains the gold standard for diagnosis of gastrointestinal (GI) cancers for subsequent management. In a traditional anatomical pathology (AP) laboratory, histopathologists are required to manually assess, quantify and classify diseases under a microscope in a semiquantitative or qualitative manner. The conversion of analogue-to-digital pathology is on the rise, conforming with trends toward digitalization. The rapid adoption of digital pathology (DP) is driven by factors such as the worldwide shortage of pathologists and medical technologists, the increasing incidence of cancer and the critical need to improve laboratory efficiency. In this review, we aim to provide a comprehensive summary of algorithms for AI detection and classification of GI cancer. We will also provide critical insight into the application of algorithms for routine care in clinical practice. The implementation of DP will revolutionize current practice by providing pathologists with additional tools and algorithms to improve workflow. Furthermore, DP will open up opportunities for development of AI-based tools for more precise and reproducible diagnosis through computational pathology. One of the key features of AI is its capability to generate perceptions and recognize patterns beyond the human senses. Thus, the incorporation of AI into DP can reveal additional morphological features and information. At the current rate of AI development and adoption of DP, the interest in computational pathology is expected to rise in tandem. There have already been promising developments related to AI-based solutions in prostate cancer detection; however, in the GI tract, development of more sophisticated algorithms is required to facilitate histological assessment of GI specimens for early and accurate diagnosis. In this review, we aim to provide an overview of the current histological practices in AP laboratories with respect to challenges faced in image preprocessing, present the existing AI-based algorithms, discuss their limitations and present clinical insight with respect to the application of AI in early detection and diagnosis of GI cancer. [ABSTRACT FROM AUTHOR]

Objective: Using artificial intelligence and a deep learning algorithm can differentiate vesicoureteral reflux and hydronephrosis reliably. Material and Methods: An online dataset of vesicoureteral reflux and hydronephrosis images were abstracted. We developed image analysis and deep learning workflow. The images were trained to distinguish between vesicoureteral reflux and hydronephrosis. The discriminative capability was quantified using receiver-operating characteristic curve analysis. We used Scikit learn to interpret the model. Results: Thirty-nine of the hydronephrosis and 42 of the vesicoureteral reflux images were abstracted from an online dataset. First, we randomly divided the images into training and validation. In this example, we put 68 cases into training and 13 into validation. We did inference on 2 cases and in return their predictions were predicted: [[0.00006]] hydronephrosis, predicted: [[0.99874]] vesicoureteral reflux on 2 test cases. Conclusion: This study showed a high-level overview of building a deep neural network for urological image classification. It is concluded that using artificial intelligence with deep learning methods can be applied to differentiate all urological images. [ABSTRACT FROM AUTHOR]

Preparing radiology examinations for interpretation requires prefetching relevant prior examinations and implementing hanging protocols to optimally display the examination along with comparisons. Body part is a critical piece of information to facilitate both prefetching and hanging protocols, but body part information encoded using the Digital Imaging and Communications in Medicine (DICOM) standard is widely variable, error-prone, not granular enough, or missing altogether. This results in inappropriate examinations being prefetched or relevant examinations left behind; hanging protocol optimization suffers as well. Modern artificial intelligence (AI) techniques, particularly when harnessing federated deep learning techniques, allow for highly accurate automatic detection of body part based on the image data within a radiological examination; this allows for much more reliable implementation of this categorization and workflow. Additionally, new avenues to further optimize examination viewing such as dynamic hanging protocol and image display can be implemented using these techniques. [ABSTRACT FROM AUTHOR]

The objective of the study was to determine if the pathology depicted on a mammogram is either benign or malignant (ductal or non-ductal carcinoma) using deep learning and artificial intelligence techniques. A total of 559 patients underwent breast ultrasound, mammography, and ultrasound-guided breast biopsy. Based on the histopathological results, the patients were divided into three categories: benign, ductal carcinomas, and non-ductal carcinomas. The mammograms in the cranio-caudal view underwent pre-processing and segmentation. Given the large variability of the areola, an algorithm was used to remove it and the adjacent skin. Therefore, patients with breast lesions close to the skin were removed. The remaining breast image was resized on the Y axis to a square image and then resized to 512 × 512 pixels. A variable square of 322,622 pixels was searched inside every image to identify the lesion. Each image was rotated with no information loss. For data augmentation, each image was rotated 360 times and a crop of 227 × 227 pixels was saved, resulting in a total of 201,240 images. The reason why our images were cropped at this size is because the deep learning algorithm transfer learning used from AlexNet network has an input image size of 227 × 227. The mean accuracy was 95.8344% ± 6.3720% and mean AUC 0.9910% ± 0.0366%, computed on 100 runs of the algorithm. Based on the results, the proposed solution can be used as a non-invasive and highly accurate computer-aided system based on deep learning that can classify breast lesions based on changes identified on mammograms in the cranio-caudal view. [ABSTRACT FROM AUTHOR]

Background: Panoramic radiography is a standard diagnostic imaging method for dentists. However, it is challenging to detect mandibular trauma and fractures in panoramic radiographs due to the superimposed facial skeleton structures. The objective of this study was to develop a deep learning algorithm that is capable of detecting mandibular fractures and trauma automatically and compare its performance with general dentists. Materials and Methods: This is a retrospective diagnostic test accuracy study. This study used a two-stage deep learning framework. To train the model, 190 panoramic images were collected from four different sources. The mandible was first segmented using a U-net model. Then, to detect fractures, a model named Faster region-based convolutional neural network was applied. In the end, a comparison was made between the accuracy, specificity, and sensitivity of artificial intelligence and general dentists in trauma diagnosis. Results: The mAP50 and mAP75 for object detection were 98.66% and 57.90%, respectively. The classification accuracy of the model was 91.67%. The sensitivity and specificity of the model were 100% and 83.33%, respectively. On the other hand, human-level diagnostic accuracy, sensitivity, and specificity were 87.22 ± 8.91, 82.22 ± 16.39, and 92.22 ± 6.33, respectively. Conclusion: Our framework can provide a level of performance better than general dentists when it comes to diagnosing trauma or fractures. [ABSTRACT FROM AUTHOR]