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A patent has been issued for a manufacturing process of intermittent coating release paper by Foshan XinFei Hygiene Materials Co. Ltd. The patent addresses the technical problems associated with the production of release paper used in sanitary napkins and other similar products. The process involves steps such as undercoating, primary drying, printing optical marks, coating silicone oil, and accurately coating heat-sealing material. The patent provides specific details about the viscosity of the silicone oil and heat-sealing material, as well as the alignment and precision of the coating rollers. The process aims to solve technical defects and meet the actual needs of the industry. [Extracted from the article]

Keywords: Business; Cannabinoids; Marijuana/Cannabis; Republic Technologies (North America) LLC; Tetrahydrocannabinol EN Business Cannabinoids Marijuana/Cannabis Republic Technologies (North America) LLC Tetrahydrocannabinol N.PAG N.PAG 1 07/17/23 20230718 NES 230718 2023 JUL 18 (NewsRx) -- By a News Reporter-Staff News Editor at Cannabis & Marijuana News -- Republic Technologies (North America) LLC (Glenview, Illinois, United States) has been issued patent number 11684081, according to news reporting originating out of Alexandria, Virginia, by NewsRx editors. Business, Cannabinoids, Marijuana/Cannabis, Republic Technologies (North America) LLC, Tetrahydrocannabinol The process according to claim 1, wherein the cannabinoid is oil-free broad-spectrum cannabidiol (CBD) and wherein the cannabinoid is heated to 70° C. with or without oil before introduction in said water. [Extracted from the article]

Such displays using solid electro-optic materials may hereinafter for convenience be referred to as "solid electro-optic displays" or "solid electro-optic devices". The invention enables the authentication of the manufacturing source and the identification of the manufacturing lot of the electro-optic device and its components at any time during the life of the electro-optic device. [Extracted from the article]

General Mills Inc. has been issued a patent for a system and method for coating soft and sticky food cores. The patent describes a process for manufacturing food products with a coating on the core, specifically addressing the challenges of coating sticky and soft food materials. The system involves using conveyor belts and a carrier sheet to support the core material and maintain its shape during the coating process. The patent also mentions the use of parchment paper and a thin layer of coating material to prevent the core from sticking to the conveyor. The invention aims to provide an efficient and effective system for producing food products with soft and sticky cores in a commercial manufacturing setting. [Extracted from the article]

A patent has been issued for an image forming apparatus by Canon Kabushiki Kaisha. The patent describes a configuration that notifies the user of the position of a recording medium remaining in the apparatus. The invention includes a conveyance unit with sensors and light sources that determine the position of a paper jam and control the corresponding light source to turn on. The apparatus also includes a capacitor to reduce voltage fluctuation and a shut-off mechanism when the conveyance unit is pulled out. The invention aims to provide a less expensive configuration for notifying paper jams in an image forming apparatus. [Extracted from the article]

The method of claim 1, further comprising triggering the knife assembly to cut in-between a first puck and a second puck to provide the first puck and the second puck on a first sheet of paper and a second sheet of paper, respectively. The method of claim 9, further comprising triggering the knife assembly not to cut in-between the second puck and a third puck to provide the second puck and the third puck on the second sheet of paper. In some embodiments, the knife assembly is triggered not to cut in-between the second puck and a third puck to provide the second puck and the third puck on the second sheet of paper. [Extracted from the article]

The beverage container packaging assembly of claim 1, wherein at least one of the beverage container support cavities include a semi-circular shape and at least one of the beverage container support cavities include a fully circular shape. The beverage container packaging assembly of claim 1, wherein a first set of the beverage container support cavities are configured to fully encapsulate the beverage container and a second set of the beverage container support cavities are configured to partially encapsulate the beverage container. The beverage container packaging assembly of claim 18, wherein a first set of the beverage container support cavities are configured to fully encapsulate the beverage container and a second set of the beverage container support cavities are configured to partially encapsulate the beverage container. [Extracted from the article]

A cover element is arranged above the strip housing element and including a machine-readable test identifier on an upper surface, and a removably attached filtering element is arranged on the hydrophobic paper-based strip housing element. The one or more testing strips received by the hydrophobic paper-based strip housing element display colorimetric results, and at least one of the machine-readable test identifier or the color reference information area identifies the test being performed. The testing strip device according to claim 1, wherein: the removably attached filtering element is adhered to the upper surface of the cover element, and the filtering element is configured to filter the sample. [Extracted from the article]

A patent has been issued for a mass spectrometry ionization-based assay that can detect enzyme activity and/or presence. The apparatus includes a spray material, a sample containing specific enzymes, a solvent to hydrate the sample and extract analytes of interest, an enzyme substrate, a power supply to create charged droplets of the analytes, and a mass spectrometer to identify the analytes and determine the presence of enzymes. The spray material can be porous or solid, and the solvent can be a single or multi-solvent. The method can be used with various samples such as blood, urine, and plasma. The patent was filed in October 2021 and published in February 2024. [Extracted from the article]

Tetra Laval Holdings & Finance S.A. has been issued a patent for a liquid food packaging material, system, and method for applying an opening to the packaging material. The patent addresses the issue of improperly applied opening devices on containers, particularly on non-white colored packaging material or packaging material with a film. The invention involves using a first contrast area printed in a first color adjacent to the pre-laminated hole to achieve high contrast and improve detection. The patent provides detailed claims and descriptions of the laminated packaging material, system, and method. [Extracted from the article]

Chundo Pharm Co. Ltd. has been issued a patent for a method of producing a test strip for detecting calcium levels in a biological fluid sample. The test strip is based on a colorimetric change and can be used to measure calcium concentrations in blood, urine, or saliva. Calcium plays a crucial role in various bodily functions, and abnormal calcium levels can indicate medical conditions such as cancer, muscle dysfunction, and bone diseases. The test strip provides an easy, inexpensive, and fast way to measure calcium levels, allowing for early detection and prevention of conditions like osteoporosis. [Extracted from the article]

A patent has been issued for nanolignocellulose compositions and the processes to produce them. Nanolignocellulose is a nanostructured material derived from biomass, primarily cellulose, hemicellulose, and lignin. It has various applications in industries such as pharmaceuticals, food packaging, textiles, and construction materials. The patent describes a process for producing nanolignocellulose with high hydrophobicity and improved properties, such as increased strength and enhanced paper quality. The nanolignocellulose composition consists of cellulose nanofibrils, cellulose microfibrils, lignin, and hemicelluloses. The patent was filed by inventors from Atlanta, Georgia, and the assignee is GranBio Intellectual Property Holdings LLC based in Thomaston, Georgia. [Extracted from the article]

Keywords: Business; Calcium Compounds; Calcium Sulfate; Chemicals; Gold Bond Building Products LLC; Inorganic Chemicals; Minerals; Sulfates; Sulfur Acids; Sulfur Compounds; Sulfuric Acids EN Business Calcium Compounds Calcium Sulfate Chemicals Gold Bond Building Products LLC Inorganic Chemicals Minerals Sulfates Sulfur Acids Sulfur Compounds Sulfuric Acids 8249 8249 1 07/31/23 20230804 NES 230804 2023 AUG 4 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Gold Bond Building Products LLC (Charlotte, North Carolina, United States) has been issued patent number 11697618, according to news reporting originating out of Alexandria, Virginia, by NewsRx editors. Patent URL (for desktop use only): https://ppubs.uspto.gov/pubwebapp/external.html?q=(11697618)&db=USPAT&type=ids Keywords for this news article include: Business, Minerals, Sulfur Acids, Sulfuric Acids, Calcium Sulfate, Sulfur Compounds, Calcium Compounds, Inorganic Chemicals, Gold Bond Building Products LLC. Business, Calcium Compounds, Chemicals, Gold Bond Building Products LLC, Inorganic Chemicals, Minerals, Sulfates, Sulfur Acids, Sulfur Compounds, Sulfuric Acids, Calcium Sulfate. [Extracted from the article]

A patent has been issued to R.J. Reynolds Tobacco Company for a multi-segment filter element that includes a smoke-altering flavorant. The invention aims to efficiently remove certain gas phase components from mainstream cigarette smoke while still maintaining desirable sensory characteristics. The filter element consists of a first section of filter material with channels for the passage of smoke, a smoke-altering material, and a second section of filter material. The patent provides detailed descriptions of the materials and configurations used in the filter element. [Extracted from the article]

A patent has been issued to Koninklijke Philips N.V. for an indicator system for a milk container and a milk storage device. The system aims to address the need for a more robust approach to labeling stored breast milk, as current methods such as masking tape or adhesive labels are not ideal. The indicator system includes a time display element with different time scales for indicating the freshness of milk stored in different conditions, such as in the fridge or freezer. The system also features indicator elements to mark the beginning and end portions of the time scales. This invention provides a simple and efficient way to track the freshness of stored milk. [Extracted from the article]

A patent has been issued to Shanghai United Imaging Healthcare Co. Ltd. for a method and device for insulating a high-voltage generator tank. The patent addresses issues such as corona discharge, electrical leakage, and the aging of transformer oil, which can affect the stability and lifespan of the high-voltage tank. The patent describes various aspects of the transformer design, including the use of insulating paper layers, fixtures, and oil barriers to improve insulation and stability. The patent also mentions the inclusion of printed circuit boards and oil passages in the transformer design. [Extracted from the article]

A patent has been issued to R.J. Reynolds Tobacco Company for a biodegradable cigarette filter. The filter is made from a fibrous tow material coated with cellulose acetate and/or plasticized cellulose acetate. The filter is designed to degrade quickly in various disposal environments, such as landfills and composting sites, while still providing the desired smoke flavor. The patent includes various claims related to the composition and manufacturing of the filter material. [Extracted from the article]

A patent has been issued to Primera Technology Inc. for a food product platform that can be used with a food product printer. The platform is designed to securely support food products and has an attachment mechanism for connecting to a printer's receiving arm. The platform can be easily attached and detached from the arm without the need for tools. The system allows for printing on a variety of food products, such as cookies, frosting sheets, and rice paper, using edible ink. [Extracted from the article]

For detection of residual liquid (water or alcohol) in the internal channels of an endoscope, compressed air is supplied to an opening on the endoscope and a piece of water indicator paper is used to catch/detect expelled liquid/moisture at the compressed air exit location. For examination of the internal channels of an endoscope, the borescope is typically inserted into the instrument channel opening at the distal tip of the endoscope. "There is currently no direct and sensitive method available for assessing endoscope channel dryness of all flexible endoscope internal channels." To use water indicator paper, compressed air is supplied to an opening on the endoscope and a piece of water indicator paper is used to catch/detect expelled liquid/moisture at the compressed air exit location. [Extracted from the article]

The apparatus of claim 12 wherein the biodegradable substance comprises hemp paper, hemp cloth, cannabis paper, cannabis cloth, leaf paper, or leaf cloth. The cartridge of claim 3 wherein the biodegradable substance comprises hemp paper, hemp cloth, cannabis paper, cannabis cloth, leaf paper, or leaf cloth. Keywords: Business; Freelander Innovations USA LLC; Marijuana/Cannabis EN Business Freelander Innovations USA LLC Marijuana/Cannabis N.PAG N.PAG 1 05/08/23 20230509 NES 230509 2023 MAY 9 (NewsRx) -- By a News Reporter-Staff News Editor at Cannabis & Marijuana News -- Freelander Innovations USA LLC (Springfield, Missouri, United States) has been issued patent number 11627758, according to news reporting originating out of Alexandria, Virginia, by NewsRx editors. [Extracted from the article]

A patent has been issued for a method and installation for producing a multi-layered wet friction material. The patent describes a method in which a bottom layer and a top layer are made independently from different materials and then bonded together. The materials are connected using temperature and pressure, either with a binder material already present in some materials or with a binder material specifically applied to the interface between the layers. The method allows for flexibility in the manufacturing process and can create friction lining thicknesses of less than one millimeter. The patent was filed by Schaeffler Technologies AG & Co. KG and published online on December 26, 2023. [Extracted from the article]

GSK Consumer Healthcare SARL has been issued a patent for a child-resistant sachet design. The sachet consists of two layers of flexible material joined together to create a cavity, with an outlet tunnel that allows for the dispensing of solid tablets. The outlet tunnel is designed with sequential sections at a non-180° angle to optimize child resistance. The patent was filed in 2016 and published in 2023. This invention aims to address the problem of children easily accessing tablets from sachets while still allowing for easy dispensing for elderly users. [Extracted from the article]

A patent has been issued for oleophilic and hydrophobic nanocellulose materials. Nanocellulose is a nanostructured material derived from biomass that has various applications, such as in polymer reinforcement, biodegradable food packaging, and pharmaceuticals. However, its use has been limited due to moisture sensitivity, incompatibility with certain polymers, and high energy consumption in production. The patent describes a process for producing nanocellulose with improved properties, including increased hydrophobicity and the ability to selectively absorb oil. The invention involves coating cellulose nanofibrils and/or cellulose nanocrystals with lignin to achieve these desired characteristics. The nanocellulose material can be in the form of a coating, layer, foam, aerogel, sponge, or lace, and can be applied to various scaffold materials. The patent also discusses the potential use of the material in oil spill clean-up. The inventors highlight the need for improved processes and materials in the production of nanocellulose. The patent was assigned to GranBio Intellectual Property Holdings LLC. [Extracted from the article]

Korber Technologies Inc. has been issued a patent for a cigarette maker. The patent describes an improved design for cigarette manufacturing machinery that is easier to disassemble and clean. It also includes a single motor for rod cutting operation, eliminating the need for two motors. The patent outlines various components and features of the machine, such as a metering device with a rotating agitator, a rotary dispenser, a chute, a cavity drum, and a metering bar. The invention aims to address the complexity, cost, and cleaning challenges associated with current cigarette producing machinery. [Extracted from the article]

A recently issued patent describes a method and device for measuring a person's health condition based on bodily fluid. The patent emphasizes the importance of hydration for runners and the potential risks of both dehydration and over-hydration. It also addresses the challenges of assessing hydration levels in children and the complications associated with dry skin. The patent proposes the use of a hydration sensor that analyzes saliva to determine a person's hydration level. Various versions of the sensor are discussed, including disposable and reusable options. The patent outlines a handheld sensing device and a sensing strip that measures a person's health condition by analyzing bodily fluid. The sensing strip consists of two water-resistant layers with conductive lines in between, allowing bodily fluid to come into contact with the conductive lines. The handheld sensing device measures an electrical characteristic across the conductive lines and provides an indication of the user's health condition. The system can also wirelessly transmit data to another device and includes a timer function. This invention is particularly beneficial for monitoring hydration levels. [Extracted from the article]

This document is a summary of a patent application for an electrosurgical system developed by Cosman Instruments LLC. The system uses radiofrequency (RF) generators and electrodes to provide pain relief or functional modification by heating target tissue. The patent application describes various techniques and considerations for tissue ablation with RF energy and electrodes, including the use of cannulas with insulated shafts and uninsulated electrode tips, as well as temperature sensors to monitor the target tissue. The application also references related research papers and books on the topic. For more detailed information, readers can refer to the patent application itself. [Extracted from the article]

"In still another aspect, a method is disclosed for manufacturing a sealed package for use in a self-heating assembly that produces heat by causing a liquid reactant to react exothermically with a solid reactant to heat a product. More specifically, the sealed package has an outer container, a lower support structure within the outer container, a layer of solid reactant above the lower support structure and within the outer container, an upper structure above the solid reactant and within the outer container, and the upper layer that is permeable to liquid and that extends across an otherwise open top of the outer container above the upper structure. The sealed package of claim 1, wherein the layer of solid reactant above the lower support structure is a layer of non-granular solid reactant. [Extracted from the article]

A patent has been issued for a method of manufacturing a glass filter for smoking smokable substances. The filter is designed to reduce the amount of tobacco residue inhaled and provide a more pleasurable smoking experience. The process involves creating indentations in a tube to form chambers for the smokable substance and the smoke, as well as a path for the smoke to flow between the chambers. The filter can be used with hand-rolled cigarettes and is reusable. The patent was filed by inventors Kim, Kyung and Ou, Suk Hwan, and assigned to R.Y.L. Inc. [Extracted from the article]

A patent has been issued for a carton designed to hold food products. The patent, filed by inventor John Murdick Holley Jr., describes a tray with multiple panels that form a rim, as well as foldable end flaps. The tray can be formed from a blank and includes features for product visibility. The patent was assigned to Graphic Packaging International LLC. [Extracted from the article]

A patent has been issued for an endotracheal tube holder device by Teleflex Medical Incorporated. The device is designed to secure and stabilize endotracheal tubes, which are used to deliver air to patients who cannot breathe on their own. The device includes a support rail, an auxiliary clip for holding accessory devices, and a tube fastener for securing the endotracheal tube. The invention aims to improve the comfort and stability of endotracheal tube placement for patients. [Extracted from the article]

A patent has been issued for a process for assembling packaging for a flexible container, particularly for use in bioreactors. The packaging includes a bottom part, a ceiling part, and struts that fix a defined distance between the two parts. The struts serve as spacers to hold the container in an unfolded condition during transport, preventing contact with internal parts. The packaging can also be used for storing the container. The patent provides a detailed process for assembling the packaging, including fixing the upper and lower portions of the container and inserting the struts. The flexible container may include a stirrer with a magnetic body and a discharge hose. The patent was filed by Diana Kronenberg and assigned to Sartorius Stedim Biotech GmbH. [Extracted from the article]

A patent has been issued to C. R. Bard Inc. for a securement device used to attach a medical article, such as a catheter, to a patient. The device aims to address the drawbacks of traditional methods of securing catheters, such as tape and sutures, which can lead to infection, motion-related complications, and skin irritation. The securement device includes anchor pads and a retainer that mechanically fixes the medical article in place without unnecessary manipulation or motion. The patent provides detailed descriptions and embodiments of the securement device. [Extracted from the article]

A patent has been issued for a smart self-activating wearable device that automatically injects medicines. The device is designed to treat acute medical conditions that require immediate treatment, such as drug overdose or anaphylactic shock. It overcomes the limitations of current automatic drug injection systems by being wearable, unobtrusive, and requiring no human intervention. The device includes an enclosure, an injection cylinder, an injection piston, hypodermic needles, and a valve member to control the flow of the injected fluid. The patent was filed by Innovative Health Strategies LLC and published online on March 5, 2024. [Extracted from the article]

A patent has been issued to Huhtamaki Inc. for a tamper-evident meal delivery carton. The invention aims to address the problem of tampering with food containers during delivery. The tamper-evident feature includes a locking tab connected to the container's cover panel and a receiving slot on the wall panel. When engaged, the feature restricts access to the container's contents and provides evidence of tampering. The invention can be used in various types of containers and has potential applications beyond the food service industry. [Extracted from the article]

Iryou Jyouhou Gijyutu Kenkyusyo Corporation, based in Fukuoka, Japan, has been issued a patent for an electronic sticky note system. The system aims to prevent work errors and improve communication in medical care and other industries by electronically creating sticky notes that can be displayed on a monitor screen when relevant records are accessed. The system includes a server, electronic record display terminals, and a local area network for communication. The patent was filed in 2016 and published online in 2024. [Extracted from the article]

A patent has been issued for a carton designed to hold food products. The carton features leak-resistant features, including a downwardly sloping arrangement of the side and end panels towards the bottom panel to create a receptacle for fluids. The patent also includes a blank for forming the carton and a method for assembling it. The patent was filed by Greg Gungner and assigned to Graphic Packaging International LLC. [Extracted from the article]

The beverage container packaging assembly of claim 1, wherein a first set of the beverage container support cavities are configured to fully encapsulate the beverage container and a second set of the beverage container support cavities are configured to partially encapsulate the beverage container. The beverage container packaging assembly of claim 1, wherein at least one of the beverage container support cavities include a semi-circular shape and at least one of the beverage container support cavities include a fully circular shape. The beverage container packaging assembly of claim 18, wherein a first set of the beverage container support cavities are configured to fully encapsulate the beverage container and a second set of the beverage container support cavities are configured to partially encapsulate the beverage container. [Extracted from the article]

Elemental Cognition Inc. has been issued a patent for an interactive research assistant tool in the field of life sciences. The tool is designed to assist researchers in finding answers to complex research questions by guiding them through the research process and connecting evidence from multiple documents. It uses a graphical user interface to present prompts and guidance for collaboration and exploration of research concepts. The tool can search, analyze, connect, aggregate, synthesize, infer, and chain together evidence from various knowledge sources, such as medical ontologies, research papers, and clinical studies. It also includes features for user feedback and ranking of evidence. [Extracted from the article]

A patent has been issued for stackable containers with a support band, which aims to improve the organization and transportation of multiple food containers and dinnerware items for takeout purposes. The system includes a plurality of stackable food service items that can be linked together by a ribbon, strip, band, or strap. The support band is threaded through strap openings in the containers and dinnerware items to stabilize the stack and provide a handhold for carrying. This invention addresses the challenges of keeping containers level, preventing spillage, and avoiding the use of plastic bags, which are being banned in some communities due to environmental concerns. The patent was filed by Waddington North America Inc. and published online on October 24, 2023. [Extracted from the article]

The image forming apparatus according to claim 9, wherein if the user interface previously switched from the touch panel to the aerial touch panel, the controller switches the user interface from the aerial touch panel to the touch panel if the body surface temperature of the operator is lower than the threshold temperature. Therefore, if a person without an infectious disease who is not infected with an infectious disease subsequently operates the touch panel, the virus adheres to the finger of the person without an infectious disease, so that the person without an infectious disease is infected and the infectious disease is sometimes widespread. [Extracted from the article]

There still remains a need for improved beverage container packaging and, more particularly, improved molded paper pulp tray packaging that can accommodate temperature or environmental control of beverage containers." The beverage container packing assembly according to claim 1, wherein the bottom tray includes one or more first support columns and the center support includes one or more second support columns that are configured to stack on one of the one or more first support columns. The beverage container packing assembly according to claim 1, wherein the center support is configured to accommodate the thermo pack such that the thermo pack extends between a plurality of beverage containers installed in the first row and a plurality of beverage containers installed in the second row. [Extracted from the article]

Heat generation apparatus for an aerosol-generation system of a smoking article, and associated smoking article. The smoking article also includes an aerosol-generation system that includes (i) a heat generation segment, and (ii) an aerosol-generating region or segment located downstream from the heat generation segment. [Extracted from the article]

A patent has been issued for skin closure systems and devices that offer improved flexibility and stretchability for bendable joints. The patent describes a device that consists of an elastic flat flexible tape with a mesh substrate and a pressure-sensitive adhesive. The tape has a plurality of openings arranged side-by-side, allowing for flexibility and joint articulation when applied over a joint. The device aims to provide secure and lasting bonding and coverage for wound healing. The patent was assigned to Ethicon LLC, a medical device company. [Extracted from the article]

Baxter International Inc. has been issued a patent for a reconstitution system that allows for the administration of medications via intravenous (IV) bags. The system includes a reconstitution device with a vent conduit, which improves the reconstitution process, especially for multi-chamber bags. The device enables the mixing of IV fluid with a drug located in a vial, and air pressure from the external environment pushes the mixed drug from the vial to the IV bag. This system aims to improve the administration of medications and provide a more efficient and convenient method for healthcare professionals. [Extracted from the article]

A patent has been issued for a microwave cooking package by Conagra Foods RDM Inc. The package is designed for microwave popcorn and is made up of vertically rigid panels and a flexible bag construction. The bag is made of a polyester film material and can be expanded or collapsed depending on the popping operation. The patent includes various claims for the design and features of the package. [Extracted from the article]

Liqui-Box Corporation has been issued a patent for a process that prevents degradation in the taste and smell of sensitive foods packaged in flexible containers. The process involves using an oxidation-resistant slip additive in the polyethylene film used for packaging. This additive reduces friction and improves the processability of the film, but traditional additives can cause off-tastes and odors when they come into contact with the food. The patented process addresses this issue by using an oxidation-resistant slip additive that does not migrate into the food. The patent provides specific examples of the types of foods and packaging that can benefit from this process. [Extracted from the article]

A patent has been issued for a catheter system designed for pediatric treatment. The system aims to reduce complications associated with catheter insertion in pediatric patients, particularly neonates, by improving catheter placement in smaller veins and minimizing unnecessary needle sticks. The system includes a catheter adapter with wings that fold upwardly and a housing to secure the wings in an upward position. The system also features a catheter cannula, a needle hub, and an introducer needle. The patent was filed by Becton Dickinson and Company and published online on January 9, 2024. [Extracted from the article]

A patent has been issued for a data logger designed for dental or medical autoclaves. Autoclaves are used to sterilize dental and medical equipment, and the data logger is intended to store and display data related to the sterilization cycles. The data logger includes a microprocessor, memory, and a visual display screen for receiving and storing data transmitted from the autoclave. The invention aims to improve the collection, storage, and verification of data associated with autoclave operations. [Extracted from the article]

A patent has been issued for a system and method for detecting a possible loss of integrity of a flexible bag used for biopharmaceutical products. The patent describes various methods for testing the integrity of the bag, including physical tests and the use of a gas tracer such as helium. The current physical methods are limited in their ability to detect microleaks in the bag, particularly holes smaller than two microns in diameter. The invention aims to provide a testing system that is highly sensitive and reliable, capable of detecting micrometric and submicrometric holes in the bag. The system involves filling the bag with helium and analyzing the pressure variation to determine if there is a leak. [Extracted from the article]