Search

Copyright of Biologie Aujourd'hui is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Anatomia Clinica is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The norepinephrine (NE) turnover times in various peripheral sympathetically innervated organs of the rat were determined by the decay in endogenous NE after inhibition of tyrosine hydroxylase by α-methylparatyrosine (α-MPT). The values for turnover times were: heart (36,0 h), sub-maxillary gland (13,7 h), femoral muscle (11,6 h), spleen (10,1 h), small intestine (4,3 h). In vas deferens, no significant depletion of the NE was observed 8 h after α-MPT administration. The influence of α-MPT treatment on the tissular uptake of a tracer dose of LH-NE was investigated. In rats pretreated with α-MPT, the uptake ofH-NE was significantly reduced in salivary glands; it was weakly but not significantly (0.1< p<0.2) reduced in spleen, muscle and small intestine and was not impaired in heart. A significant augmentation of the hepatic radioactivity was seen in treated animals which could be interpreted as the consequence of the decrease of the neuronalH-NE uptake. The validity of α-MPT utilization for measuring NE turnover is discussed and the values for turnover time yielded by α-MPT have been compared with that obtained from an isotopic method (decline in radioactivity after labeling withH-NE): the results of the two methods showed obvious discrepancies. In heart and submaxillary gland, the turnover times determined by isotopic method were shorter than those obtained by means of α-MPT: in spleen, muscle and small intestine, inverse variations were observed, the α-MPT method leading to shorter turnover times. This suggests that the sources of error inherent to each method are of variable importance according to the nature of the organ. [ABSTRACT FROM AUTHOR]

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Zeitschrift Für Zellforschung und Mikroskopische Anatomie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)