Search

A recent study conducted by researchers at the All India Institute of Medical Sciences (AIIMS) in Chhattisgarh, India, explored the relationship between dyslipidemia (abnormal lipid levels) and systemic lupus erythematosus (SLE), an autoimmune disease. The study found that patients with high disease activity in SLE had a significant decline in high-density lipoprotein (HDL) and apolipoprotein A1 levels compared to those with low disease activity. The researchers also discovered that interleukin-10 (IL-10), an inflammatory factor, was strongly associated with the decline in HDL. This finding suggests that IL-10 could be a potential target for reducing cardiovascular risk in SLE patients. [Extracted from the article]

A researcher from Chhattisgarh, India has published new studies and findings on membranous nephropathy, specifically focusing on filariasis-associated secondary membranous nephropathy. The research highlights the importance of serological tests to detect circulating Wuchereria bancrofti antigens or the identification of microfilariae in the capillary lumen on kidney biopsy for diagnosis. The study reports a case of a 30-year-old woman with nephrotic syndrome who was diagnosed with secondary membranous nephropathy and treated with diethylcarbamazine and other supportive medications, resulting in a marked resolution of proteinuria. This research provides valuable insights into a rare presentation of membranous nephropathy associated with filariasis. [Extracted from the article]