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The climb of Gasherbrum IV's (7,925 m) 'Shining Wall' in 1985 by Voytek Kurtyka and Robert Schauer is considered one of the greatest mountaineering achievements in the twentieth century, even though the two climbers did not reach the summit. The article explores three ways of understanding mountaineering without the objective of reaching the summit. I start with a game-playing approach and then a view on mountaineering that takes its inspiration from deep ecology and argue that while both have the potential for explaining important aspects of mountaineering, neither will fully account for the value of climbing mountains without summiting. Finally, I argue that we can supplement either of these two views with a radically different way of understanding mountaineering, which involves creating and appreciating a work of art. [ABSTRACT FROM AUTHOR]

i points beyond itself as it stylizes the ambiguity inherent in all things that are made: their capacity to include I and i exclude, protect I and i harm, create I and i destroy. Heaton's I Zen Men i are lumped together; in one we can just about make out a thinker's pose, while the other merely slouches. i (2007, see Figure 1) by Southport- and London-based sculptor and performance artist Tony Heaton, we first encounter an uninviting fortress made from the same stone as St Paul's Cathedral, Buckingham Palace, and the Bank of England. The original blue (which, Heaton notes, became derogatively known as spaz blue) turns into lamé, a shimmering fabric, which is a play on the word I lame i , indicating the fickle balance between ability and disability. [Extracted from the article]

The immunopathogenesis of HIV infection remains poorly understood. Despite the widespread use of effective modern antiretroviral therapy (ART), people living with HIV (PLWH) are known to develop several comorbidities, including type 1 diabetes (T1DM). However, the etiology and critical mechanisms accounting for the onset of T1DM in the preceding context remain unknown. This article proposes to address this topic in order to provide further understanding and future research directions. [ABSTRACT FROM AUTHOR]

Does congruence between auditory and visual modalities affect aesthetic experience? While cross-modal correspondences between vision and hearing are well-documented, previous studies show conflicting results regarding whether audiovisual correspondence affects subjective aesthetic experience. Here, in collaboration with the Kentler International Drawing Space (NYC, USA), we depart from previous research by using music specifically composed to pair with visual art in the professionally-curated Music as Image and Metaphor exhibition. Our pre-registered online experiment consisted of 4 conditions: Audio, Visual, Audio-Visual-Intended (artist-intended pairing of art/music), and Audio-Visual-Random (random shuffling). Participants (N = 201) were presented with 16 pieces and could click to proceed to the next piece whenever they liked. We used time spent as an implicit index of aesthetic interest. Additionally, after each piece, participants were asked about their subjective experience (e.g., feeling moved). We found that participants spent significantly more time with Audio, followed by Audiovisual, followed by Visual pieces; however, they felt most moved in the Audiovisual (bi-modal) conditions. Ratings of audiovisual correspondence were significantly higher for the Audiovisual-Intended compared to Audiovisual-Random condition; interestingly, though, there were no significant differences between intended and random conditions on any other subjective rating scale, or for time spent. Collectively, these results call into question the relationship between cross-modal correspondence and aesthetic appreciation. Additionally, the results complicate the use of time spent as an implicit measure of aesthetic experience. [ABSTRACT FROM AUTHOR]

Art research has long aimed to unravel the complex associations between specific attributes, such as color, complexity, and emotional expressiveness, and art judgments, including beauty, creativity, and liking. However, the fundamental distinction between attributes as inherent characteristics or features of the artwork and judgments as subjective evaluations remains an exciting topic. This paper reviews the literature of the last half century, to identify key attributes, and employs machine learning, specifically Gradient Boosted Decision Trees (GBDT), to predict 13 art judgments along 17 attributes. Ratings from 78 art novice participants were collected for 54 Western artworks. Our GBDT models successfully predicted 13 judgments significantly. Notably, judged creativity and disturbing/irritating judgments showed the highest predictability, with the models explaining 31% and 32% of the variance, respectively. The attributes emotional expressiveness, valence, symbolism, as well as complexity emerged as consistent and significant contributors to the models' performance. Content-representational attributes played a more prominent role than formal-perceptual attributes. Moreover, we found in some cases non-linear relationships between attributes and judgments with sudden inclines or declines around medium levels of the rating scales. By uncovering these underlying patterns and dynamics in art judgment behavior, our research provides valuable insights to advance the understanding of aesthetic experiences considering visual art, inform cultural practices, and inspire future research in the field of art appreciation. [ABSTRACT FROM AUTHOR]

Background: The military is a male-dominated environment and culture in which women veterans can experience significant institutional prejudice. Transition can be confusing and isolating for women veterans. Group programs are an important source of transition support. However, we know little about the specific group program needs of women veterans. Objectives: To examine mental health and well-being support group programs delivered to women veterans, to understand what they value and find most helpful. Eligibility Criteria: Women military veterans (all types); empirical studies using any design; published between 1990 and 2022; group programs focused on transition issues (such as housing, employment, education, physical health, mental health). Sources of Evidence: Peer-reviewed journals and theses. Charting Methods: Six databases searched: Medline (via Ovid SP), PsycINFO (via Ovid SP), EmCare (via Ovid SP), CINAHL, Scopus, and ProQuest. Results: There was significant heterogeneity across 35 included studies in type of groups, program content and structure, length of sessions, measurement of impact, follow-up, and so forth. Most programs were delivered face to face. Physical health and preventative healthcare were important topics for women veterans, particularly reproductive health, mental health, and chronic pain. Groups that included physical activity, creative arts, and alternative therapies were beneficial to women's physical and mental health. Strengths-based women-only groups, facilitated by women, that created safe spaces for women veterans to share their experiences, enhanced self-expression, agency, and self-empowerment. This was particularly important for women who had experience military sexual trauma. Conclusion: This review found a small but diverse range of group programs available for women veterans. Many program evaluations were of moderate or low quality and lacked sufficient information to determine whether benefits were sustained over time. No studies involved Australian women veterans. Despite these concerns, this review highlighted several useful lessons that could help inform improved design, delivery, and evaluation of group programs for women veterans. Plain language summary: Review of women veteran transition mental health and well-being support group programs Women veterans learn to become soldiers, sailors and aviators in a male-dominated environment and culture in which their presence is highly visible, challenged and often subject to institutional prejudice. Transition can be confusing and isolating for women veterans. We know little about the specific needs of women veterans to support them to transition successfully to civilian life. Group programs are an important source of transition and post-transition support for veterans. The aim of this review was to examine the existing literature on mental health and well-being support group programs delivered to women veterans to understand what women veterans value and find most helpful in the design and delivery of such programs. Thirty-five studies were included in this review; 33 of these were conducted in the United States. They were of mixed quality and diverse design. Women only groups were favored. Strengths-based Programs that help to build emotional strengths, agency and empowered women were valued by them. Physical health and preventative healthcare are important topics for group programs for women veterans, as are creative arts and alternative therapies that facilitate self-expression and self-empowerment. [ABSTRACT FROM AUTHOR]

Background: A dolutegravir (DTG)-based antiretroviral regimen has been rolled out for pregnant women in low- and middle-income countries since 2020. However, available safety data are limited to a few clinical trials and observational studies. Hence, we present real-world pregnancy and birth outcome safety data from a large sample multicenter cohort study in Ethiopia. Methods: A retrospective cohort study was conducted in fourteen hospitals across Ethiopia from 2017 to 2022. HIV-infected pregnant women were followed from the date of prevention of mother-to-child transmission (PMTCT) care enrolment until the infant was 6–8 weeks old. The primary safety outcome was a composite of adverse pregnancy events comprising spontaneous abortion, intrauterine fetal death (IUFD) before onset of labor, preterm birth, and maternal death. Additionally, a composite adverse birth outcome was assessed, comprising intrapartum fetal demise, low birth weight, and neonatal death. Finally, a composite of adverse pregnancy or birth outcome was also investigated. The exposure of interest was the antiretroviral treatment (ART) regimen used during pregnancy for PMTCT of HIV. Results: During the study period, 2643 women were enrolled in routine PMTCT care. However, 2490 (92.2%) participants were eligible for the study. A total of 136/1724 (7.9%, 95% CI: 6.7–9.3%) women experienced adverse pregnancy outcomes. Fewer women in the DTG-based group (5.4%, 95% CI: 3.7–7.5%) had adverse pregnancy outcomes than in the Efavirenz (EFV)-based group (8.3%, 95% CI: 6.6–10.3%), P = 0.004. After controlling for baseline differences, the DTG group had a 43% lower risk of adverse pregnancy outcomes (adjusted odd ratio (AOR), 0.57; 95% CI, 0.32–0.96%) and a 53% lower risk of preterm birth (AOR, 0.47; 95% CI, 0.22–0.98%) compared to the EFV group. A total of 103/1616 (6.4%, 95% CI: 5.2–7.7%) women had adverse birth outcomes. Although the difference was not statistically significant, fewer women in the DTG group (30/548; 5.5%, 95% CI: 3.7–7.7%) than in the EFV group (57/830; 6.9%, 95% CI: 5.2–8.8%) had adverse birth outcomes. Conclusions: In this study, we observed that DTG-based regimens were associated with better pregnancy and birth outcome safety profiles, reaffirming the WHO recommendation. However, a prospective study is recommended to assess uncaptured maternal and perinatal adverse outcomes, such as congenital abnormalities, and infant growth and neurocognitive development. [ABSTRACT FROM AUTHOR]

Dorothy Shepherd (1916–1992), a scholar of Ancient Near Eastern and Islamic art, helped lay the groundwork for scholarship in her field during a period when curatorial work and scholarship was dominated by men. She attended the University of Michigan and after graduation was appointed assistant curator of decoration at the Cooper Union Museum, New York. During World War II Shepherd served in the newly formed Monuments, Fine Arts, and Archives Section of the United States military and in 1947 was appointed associate curator of textiles at the Cleveland Museum of Art (CMA); she retired from the CMA in 1981. During Shepherd's tenure, the CMA acquired textiles and Islamic objects, and organized textile exhibitions showcasing Cleveland's collection; Shepherd also authored numerous publications. In addition, Shepherd produced a significant but as yet unpublished catalog of 280 Islamic textiles in Cleveland's collection. All of this is evidence of a noteworthy career that deserves further study and recognition. [ABSTRACT FROM AUTHOR]

This scoping review aims to describe the range of research studies using arts-based data collection methods with immigrant and racialized older adults. A secondary aim is to identify challenges and strengths of using these approaches with this population. This review uses Arksey and O'Malley's five-stage scoping review framework with a final number of 16 references included for the study. Enhanced social connectedness, increased transparency and quality of findings, and self-empowerment were key strengths of using arts-based approaches for data collection. Challenges identified included resource limitations, cultural and language barriers, and barriers to meaningful engagement. Only a small number of studies have utilized arts-based methods with immigrant and racialized older adults. Arts-based approaches require unique methodological adaptations with this population but have the potential to increase engagement in research activities, authenticity of research findings and empowerment of older adults. [ABSTRACT FROM AUTHOR]

Inspired by critical trauma and embodiment theories, this study aims to illustrate how an arts-based approach such as body mapping assists in exploring the lived experiences of youth, potentially serving as a trauma-informed approach. This qualitative study collaborated with street-involved and homeless youth (SIHY) who have eating struggles while living in situations of food insecurity and other forms of oppression. Eleven participants partook in three individual face-to-face interview sessions and one arts-based body map activity, respectively, at a local SIHY resource centre in a metropolitan city in Canada. Guided by Interpretative Phenomenological Approach (IPA), our findings illustrated how body mapping (1) enabled a deepened understanding of SIHY's eating struggles as both a form of suffering and an embodied means of coping with food insecurity and other systemic and relational trauma(s); (2) provided a transformative experience leading to greater self-compassion and healing; and (3) served as a trauma-informed method that fostered choice and validation. We attest that, as a creative and supportive clinical and research tool, body mapping taps into the unspoken, expressive, embodied, and somatic aspects of eating struggles, food insecurity, poverty, and other forms of oppression deepening knowledge and informing social work research and practice. [ABSTRACT FROM AUTHOR]

In the Western context of delayed motherhood and declining fertility, an array of fertility enhancements have emerged. While bioethical debates and literature on the technological prowess of these enhancements proliferate, it is useful to explore the lived experience of women undergoing them. This article uses Tabitha Moses' artwork Investment, a series of embroidered hospital gowns, as a vehicle to explore lived experience of women engaging with fertility enhancements, including in vitro fertilisation. This analysis challenges dominant biomedical and corporate discourses framing fertility enhancements as benign. Using constructs of patriarchy, biopower, biopolitics (Foucault), and technobiopower (Haraway), we identify how power over women's bodies is extended through fertility enhancements. Haraway's notion of figuration supports the analysis. Understood as a tropic melding of semiotic and material, the figuration of The Infertile Woman offers a way to explore discursive operations of power and amid them the creation of a new form of reproductive labour. [ABSTRACT FROM AUTHOR]

In 2016 the National Museum in Oslo launched a nationwide touring exhibition that allowed visitors for the first time to touch the sculptures of modernist Aase Texmon Rygh. The aim was to encourage visitors to experience these abstract stone works through the body before engaging with various contextualising practices for a more comprehensive process of meaning-making. Allowing members of the public to touch original sculpture in an exhibition context was new not only for the National Museum but also internationally, and the exhibition generated considerable professional and media attention. In my role as the exhibition's curator, I set out to investigate the interdisciplinary process of developing the exhibition concept and the audience response through a practice-led research project. Drawing on different theoretical perspectives, such as learning theory and interdisciplinary sensory research, and audience surveys which were conducted during the exhibition, I wanted to learn more about how audiences experienced touching the sculptures, and how touch affected their process of meaning making. In this paper, I share some of my findings and also reflect on the importance of practitioners doing research on their own practice. [ABSTRACT FROM AUTHOR]

This essay considers a painting from Rene Magritte, The Treachery of Images, also known as "This is not a pipe," the translation of the prominent statement Ceci n'est pas une pipe in the painting, which Barbara Buttenfield had prominently placed in her University of Buffalo office. It is an iconic and surrealistic twentieth century artwork (with a second version), widely copied and readily available online. Its visual juxtaposition of a textual element and detailed realist painting of a classical smoker's pipe can quickly become more than a surrealistic play with words and images and poignantly stimulates associations and disconnections between image and object, text and object, and text and image. Viewers can also see a relevance of this painting to a number of representational issues involving images and maps. However, I want to focus in this essay on just two questions: 1) why do people affirm the connections between graphical map images and graphics in light of a fundamental disconnection between map and the represented territory or objects and 2) how do people still find sense in maps after we acknowledge the limits of any sense of correspondence between map image and experienced geography? [ABSTRACT FROM AUTHOR]

This systematic review of art psychotherapy literature explored how art therapy or artmaking may support patient identity after a life-limiting diagnosis. Background: Previous research shows the value of art therapy and artmaking in reducing physical and psychological symptoms at the end-of-life. Recent reports indicated that disruption to identity is a key challenge to this group of individuals. Aims: This systematic review investigated art therapy and artmaking and examined and built upon previous research undertaken with patients facing identity concerns after a terminal diagnosis. Methods: A robust and rigorous framework of criteria (PRISMA), was followed to select and review suitable research papers in order to gain new insights. Results: The results indicate that many patients struggle to cope with a changing identity alongside the demands of a terminal illness. The key findings are threefold: art therapy and artmaking can help maintain or reconstruct a pre-illness identity and art therapy in particular can help enable a positive identity transformation. Conclusions: Art therapy and artmaking hold benefits for positive identity support such as the re-evaluation and reinstatement of pre-illness roles, psychosocial-interventions and adjustment to major life changes. Implications: It is recommended that art therapy and artmaking are offered to terminal patients at diagnosis, in order to support identity concerns promptly and allow patients to focus solely on their quality of life and limited time left. It is anticipated that the findings of this systematic review will be of benefit to patients, healthcare workers, art therapists and others within the palliative care community. Plain-language summary: This review of art therapy literature explored how art therapy or artmaking may support patient identity after a life-limiting diagnosis. Previous research has showed the value of art therapy and artmaking in reducing concerns at the end-of-life. Many reports indicated that changes to identity are one of the main challenges to this group of individuals. This review aimed to compare art therapy and artmaking. It examined and added to earlier research with patients struggling with identity concerns after a terminal diagnosis. A set of standards were followed to select and review appropriate research papers. Results showed that many patients struggled to cope with a changing identity alongside the difficulties of a terminal illness. Patients tried to keep an identity that was separate from their illness and also maintain their pre-illness roles. The main findings of this systematic review are that art therapy and artmaking can help keep or restore a pre-illness identity. Art therapy in particular can help bring about a positive identity change. The conclusions are that art therapy and artmaking are beneficial for supporting identity and help patients think about and recover their pre-illness roles. Art therapy and artmaking are also seen to help patients cope with major life changes. Recommendations are that further research is undertaken with larger, more varied groups of people, particularly males. It is recommended that art therapy and artmaking are offered to terminal patients when they are diagnosed. This would allow patients to focus on their wellbeing and their limited time left with loved ones. It is likely that the findings will be helpful to patients, healthcare workers, art therapists and others within palliative care. [ABSTRACT FROM AUTHOR]

Background/Objectives: Women with subclinical hypothyroidism (SCH) were reported to be at an increased perinatal risk. We aimed to investigate the relationship between SCH and perinatal outcomes in singleton pregnancies resulting from assisted reproduction technology (ART). Methods: We retrospectively examined the perinatal outcomes of ART singleton pregnancies in women who underwent thyroid function screening before conception and delivered at our hospital from January 2020 to July 2023. We defined SCH as thyroid-stimulating hormone (TSH) levels > 2.5 mU/L and normal free T4 levels. The patients were categorized into three groups: normal thyroid function (group A), SCH without levothyroxine therapy (group B), and SCH with levothyroxine therapy (group C). The risks of preterm birth, preeclampsia, fetal growth restriction, manual placental removal, and blood loss at delivery were compared among the three groups. Results: Out of the 650 ART singleton deliveries, 581 were assigned to group A, 34 to group B, and 35 to group C. The preterm birth rate at <34 weeks was significantly higher in group B and significantly lower in group C than in group A. The rate of preterm delivery at <34 weeks increased in correlation with TSH levels. Levothyroxine therapy was the significant preventive factor for preterm birth at <34 weeks. Conclusions: The preterm birth rate before 34 weeks was significantly higher in the SCH group. Levothyroxine therapy is a significant protective factor against preterm birth before 34 weeks. Universal screening for thyroid function and appropriate hormone therapy in pregnant women may help reduce perinatal risks, including preterm birth. [ABSTRACT FROM AUTHOR]

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This article was published open access under a CC BY-NC-ND Licence. https://creativecommons.org/licenses/by-nc-nd/4.0/ [ABSTRACT FROM AUTHOR]

STUDY QUESTION How are ART and IUI regulated, funded, and registered in European countries, and how has the situation changed since 2018? SUMMARY ANSWER Of the 43 countries performing ART and IUI in Europe, and participating in the survey, specific legislation exists in only 39 countries, public funding varies across and sometimes within countries (and is lacking or minimal in four countries), and national registries are in place in 33 countries; only a small number of changes were identified, most of them in the direction of improving accessibility, through increased public financial support and/or opening access to additional subgroups. WHAT IS KNOWN ALREADY The annual reports of the European IVF-Monitoring Consortium (EIM) clearly show the existence of different approaches across Europe regarding accessibility to and efficacy of ART and IUI treatments. In a previous survey, some coherent information was gathered about how those techniques were regulated, funded, and registered in European countries, showing that diversity is the paradigm in this medical field. STUDY DESIGN, SIZE, DURATION A survey was designed using the SurveyMonkey tool consisting of 90 questions covering several domains (legal, funding, and registry) and considering specific details on the situation of third-party donations. New questions widened the scope of the previous survey. Answers refer to the situation of countries on 31 December 2022. PARTICIPANTS/MATERIALS, SETTINGS, METHODS All members of the EIM were invited to participate. The received answers were checked and initial responders were asked to address unclear answers and to provide any additional information considered relevant. Tables resulting from the consolidated data were then sent to members of the Committee of National Representatives of ESHRE, requesting a second check. Conflicting information was clarified by direct contact. MAIN RESULTS AND THE ROLE OF CHANCE Information was received from 43 out of the 45 European countries where ART and IUI are performed. There were 39 countries with specific legislation on ART, and artificial insemination was considered an ART technique in 33 of them. Accessibility is limited to infertile couples only in 8 of the 43 countries. In 5 countries, ART and IUI are permitted also for treatments of single women and all same sex couples, while a total of 33 offer treatment to single women and 19 offer treatment to female couples. Use of donated sperm is allowed in all except 2 countries, oocyte donation is allowed in 38, simultaneous donation of sperm and oocyte is allowed in 32, and embryo donation is allowed in 29 countries. Preimplantation genetic testing (PGT)-M/SR (for monogenetic disorders, structural rearrangements) is not allowed in 3 countries and PGT-A (for aneuploidy) is not allowed in 10; surrogacy is accepted in 15 countries. Except for marital/sexual situation, female age is the most frequently reported limiting criterion for legal access to ART: minimal age is usually set at 18 years and the maximum ranges from 42 to 54 with some countries not using numeric definition. Male maximum age is set in very few countries. Where third-party donors are permitted, age is frequently a limiting criterion (male maximum age ranging from 35 to 50; female maximum age from 30 to 37). Other legal restrictions in third-party donation are the number of children born from the same donor (or, in some countries, the number of families with children from the same donor) and, in 12 countries, there is a maximum number of oocyte donations. How countries deal with the anonymity is diverse: strict anonymity, anonymity just for the recipients (not for children when reaching legal adulthood age), a mixed system (anonymous and non-anonymous donations), and strict non-anonymity. Inquiring about donors' genetic screening showed that most countries have enforced either mandatory or scientific recommendations that exclude the most prevalent genetic diseases, although, again, diversity is evident. Reimbursement/compensation systems exist in more than 30 European countries, with around 10 describing clearly defined maximum amounts considered acceptable. Public funding systems are extremely variable. One country provides no financial assistance to ART/IUI patients and three offer only minimal support. Limits to the provision of funding are defined in the others i.e. age (female maximum age is the most used), existence of previous children, BMI, maximum number of treatments publicly supported, and techniques not entitled for funding. In a few countries reimbursement is linked to a clinical policy. The definitions of the type of expenses covered within an IVF/ICSI cycle, up to which limit, and the proportion of out-of-pocket costs for patients are also extremely dissimilar. National registries of ART are in place in 33 out of the 43 countries contributing to the survey and a registry of donors exists in 19 of them. When comparing with the results of the previous survey, the main changes are: (i) an extension of the beneficiaries of ART techniques (and IUI), evident in nine countries; (ii) public financial support exists now in Albania and Armenia; (iii) in Luxembourg, the only ART centre expanded its on-site activities; (iv) donor-conceived children are entitled to know the donor identity in six countries more than in 2018; and (v) four more countries have set a maximum number of oocyte donations. LIMITATIONS, REASONS FOR CAUTION Although the responses were provided by well-informed and committed individuals and submitted to double checking, no formal validation by official bodies was in place. Therefore, possible inaccuracies cannot be excluded. The results presented are a cross-section in time, and ART and IUI frameworks within European countries undergo continuous modification. Finally, some domains of ART activity were deliberately left out of the scope of this survey. WIDER IMPLICATIONS OF THE FINDINGS Our results offer a detailed updated view of the ART and IUI situation in European countries. It provides extensive answers to many relevant questions related to ART usage at the national level and could be used by institutions and policymakers at both national and European levels. STUDY FUNDING/COMPETING INTEREST(S) The study has no external funding, and all costs were covered by ESHRE. There were no competing interests. [ABSTRACT FROM AUTHOR]

Recent advances in preimplantation genetic testing for aneuploidy (PGT-A) have significantly enhanced its application in ART, providing critical insights into embryo viability, and potentially reducing both the time spent in fertility treatments and the risk of pregnancy loss. With the integration of next-generation sequencing, PGT-A now offers greater diagnostic precision, although challenges related to segmental aneuploidies and mosaicism remain. The emergence of non-invasive PGT-A (niPGT-A), which analyzes DNA in spent embryo culture media, promises a simpler aneuploidy screening method. This mini review assesses the methodological criteria for test validation, the current landscape of PGT-A, and the potential of niPGT-A, while evaluating its advantages and potential pitfalls. It underscores the importance of a robust three-phase validation process to ensure the clinical reliability of PGT-A. Despite initial encouraging data, niPGT-A not only confronts issues of DNA amplification failure and diagnostic inaccuracies but also has yet to meet the three-prong criteria required for appropriate test validation, necessitating further research for its clinical adoption. The review underscores that niPGT-A, like traditional PGT-A, must attain the high standards of precision and reliability expected of any genetic testing platform used in clinical settings before it can be adopted into routine ART protocols. [ABSTRACT FROM AUTHOR]

Quality healthcare requires two critical components: patients' best interests and best decisions to achieve that goal. The first goal is the lodestar, unchanged and unchanging over time. The second component is a more dynamic and rapidly changing paradigm in healthcare. Clinical decision-making has transitioned from an opinion-based paradigm to an evidence-based and data-driven process. A realization that technology and artificial intelligence can bring value adds a third component to the decision process. And the fertility sector is not exempt. The debate about AI is front and centre in reproductive technologies. Launching the transition from a conventional provider-driven decision paradigm to a software-enhanced system requires a roadmap to enable effective and safe implementation. A key nodal point in the ascending arc of AI in the fertility sector is how and when to bring these innovations into the ART routine to improve workflow, outcomes, and bottom-line performance. The evolution of AI in other segments of clinical care would suggest that caution is needed as widespread adoption is urged from several fronts. But the lure and magnitude for the change that these tech tools hold for fertility care remain deeply engaging. Exploring factors that could enhance thoughtful implementation and progress towards a tipping point (or perhaps not) should be at the forefront of any 'next steps' strategy. The objective of this Opinion is to discuss four critical areas (among many) considered essential to successful uptake of any new technology. These four areas include value proposition, innovative disruption, clinical agency, and responsible computing. [ABSTRACT FROM AUTHOR]

STUDY QUESTION Is IVF indicated for couples with age-related infertility? SUMMARY ANSWER IVF may be of doubtful utility for age-related infertility. WHAT IS KNOWN ALREADY A diagnosis of unexplained infertility is drawn when the diagnostic work-up fails to identify any patent cause. Although typically managed uniformly, unexplained infertility is likely to comprise a wide range of conditions, including age-related infertility (at least in older women). Unfortunately, no validated tests for the identification of age-related infertility exist and these women are typically treated as unexplained cases. However, homologous ART may be less effective for these women because these techniques may be unable to treat the detrimental effects of ageing on oocyte competence. STUDY DESIGN, SIZE, DURATION Women aged 18–42 years who underwent IVF procedures between January 2014 and December 2021 were selected retrospectively. In the first part of the study, we aimed to assess whether the proportion of women with unexplained infertility (i.e. without patent causes of infertility) increased with age. In the second part of the study, women with unexplained infertility were matched 1:1 by age, study period, and duration of infertility, to those with a patent cause of infertility. If our hypothesis is valid, the first part of the study should highlight an increase in the proportion of unexplained infertility with age. Moreover, in the second part of the study, one should observe a sharper decrease in the rate of IVF success of the procedure with age in women with an unremarkable work-up compared to those with a definite cause of infertility. PARTICIPANTS/MATERIALS, SETTING, METHODS Women were included if: they had been trying to conceive for more than 2 years, they had retrieved more than three oocytes, and had not undergone previous IVF attempts. We exclude couples with severe male factor (criptozoospermia), chronic anovulation, untreated hydrosalpinx, or intracavitary diseases. The first part of the study aimed at investigating the relative proportion of unexplained infertility with age. The outcome of the second part was the distribution of the live births between unexplained versus explained infertility, in women younger or older than 35 years. Only the results of the first IVF cycle were considered (including both fresh and frozen cycles). The live birth rate corresponded to the cumulative chance of a live birth per oocyte retrieval. MAIN RESULTS AND THE ROLE OF CHANCE One thousand five hundred and thirty-five women were selected for the first part of the study; 742 of them had unexplained infertility (48%). The frequency of this diagnosis was lower among women aged <35 years (40%) compared to those ≥35 years (52%) (P  < 0.001). A clear gradient emerged when considering smaller intervals of age (P  < 0.001). A total of 1134 women (567 unexplained cases and 567 explained cases) were selected for the second part of the study. Baseline variables were comparable between women with unexplained and explained infertility. Among women younger than 35 years (n = 229 unexplained cases and 229 explained cases), 108 live births were observed in women with unexplained infertility (47%) and 88 in those with explained infertility (38%). In comparison, among women older than 35 years, the live births occurred in 90 (27%) and 114 (34%) couples, respectively (P  = 0.03). The adjusted odds ratio (OR) for a live birth in older women with unexplained infertility was 0.63 (95% CI: 0.43–0.94). In other words, the effectiveness of IVF in older women with unexplained infertility is reduced by an additional 37% when compared to women of similar age with a patent cause of infertility. Moreover, when considering smaller intervals of age, a gradient of the adverse effect of age on the distribution of live births between unexplained and explained infertility emerged (P  = 0.003). Overall, these results support the hypothesis that IVF may be of modest benefit in women with age-related infertility. The decline in IVF success is sharper in women with unexplained infertility compared to those with explained infertility, indirectly suggesting that IVF cannot effectively treat age-related infertility. LIMITATIONS, REASONS FOR CAUTION We postulated that the greater decline in IVF success with age in the unexplained group could be related to the concomitant increase in the proportion of women with age-related infertility. However, even if this is theoretically logical, the unavailability of validated tools to diagnose age-related infertility makes our inference speculative. We cannot exclude that the prevalence of other unknown causes of infertility that cannot also be effectively overcome with IVF could increase with age. WIDER IMPLICATIONS OF THE FINDINGS Our findings suggest that IVF may be of modest utility for treating age-related infertility. Offering this procedure to older women with an unremarkable infertility work-up may be questioned. However, the diagnosis of age-related infertility remains challenging and identifying a biomarker that could reliably diagnose age-related infertility is a priority. STUDY FUNDING/COMPETING INTEREST(S) The study was partially funded by the Italian Ministry of Health—current research IRCCS and by a specific grant supported by Ferring. ES declares receiving honoraria for lectures at meetings from IBSA and Gedeon-Richter and he also handles private grants of research from Ferring, IBSA, Theramex, and Gedeon-Richter. All the other authors do not have any conflict of interest to declare. TRIAL REGISTRATION NUMBER N/A. [ABSTRACT FROM AUTHOR]

The "Stories of stories" project, using a humanistic approach, aims to (a) shed light on the impact of clowns' artistic work, in the hospital, as a play with consequences, rather than shallow entertainment and (b) contribute to the refinement and improvement of the clown artists' intervention quality, bringing hypotheses of reflection hardly within reach during their improvised performance. We are interested in the subjective experience of the artists. The present analysis was developed from the clown's written reports after visiting the pedopsychiatry ward in a Portuguese public hospital. The visit was performed by a clown's dyad, and the audience was young teenage girls with anorexia. Public Significance Statement: This article aims to unveil the meaning and deepness of Doctor Clowns' encounters with children, their caregivers, and hospital professionals. It also aims to contribute to the improvement and growing awareness of the artists, regarding their professional training when intervening in a context of vulnerability, such as the hospital, and an especially vulnerable audience, sick or injured children and adolescents. [ABSTRACT FROM AUTHOR]

Supernormal stimuli were first defined in ethology as exaggerated forms of natural or artificial stimuli able to elicit amplified responses in animals. After the characterisation of supernormal stimuli in ethology, many scholars have explored the idea of supernormality also with reference to human cultures, resulting in the assignment of this attribute to several categories of stimuli, from pornography to fast-food. In the last decades, also art has been proposed to act as a supernormal stimulus for human beings. After reviewing the major contributions in this field, here we explore this hypothesis by highlighting experimental evidence from studies in neuroaesthetics and art history cases that corroborate this view in an attempt to show the potential that this framework can bring to the aesthetic debate. [ABSTRACT FROM AUTHOR]

In an age where the worlds of art and science continuously collide, scholars and storytellers alike are increasingly using Artificial Intelligence (AI) to analyze and represent their internal worlds. As AI becomes further enmeshed in the everyday experience of humans and other sentiences across the planet, questions begin to arise concerning ethical representation of the self and other, technological anthropomorphism, and artistic expression. Our dialogue contains several modalities: text, poetry, artistic thought experiments, speculative compositions and images. Our aim is not to provide answers to these ever-accelerating questions about AI, but to open up and expose the grooves of various narratives surrounding AI by engaging with experimentation, dialogue, and speculation as modes of discovery. Each section of the text begins with a poetic provocation by S. J. Abiodun, and continues on with an exchange between the two authors, fluidly leaping between our individual and collective knowledge as researchers, artists, and interdisciplinarians. [ABSTRACT FROM AUTHOR]

Abstract: Almost every culture engages actively with the arts. Here, we explored how contextual information about content, artist, and technique impacts aesthetic experience. Contextual information increased aesthetic ratings for artworks in Indian and Northern American participants, especially in people more open to experience, and Northern American participants with low art experience. Contextual information reduced the ingroup bias for artworks, suggesting exposure to art may be a potential vehicle to mitigate prejudice against unfamiliar cultures. Similarities and differences in the routes to broader valuations of liking and beauty point to both anthropological universals and cultural specifics of the aesthetic experience. [ABSTRACT FROM AUTHOR]

Nexus Network Journal guest editor Roberta Spallone introduces papers selected from the Nexus Conference 2023 in Turin for detailed review, expansion and development. These papers identify close links between architecture, mathematics, and specific areas of interest related to historical periods, architectural cultures, typological elements, and analysis tools. [ABSTRACT FROM AUTHOR]

This article describes a community collaborative project, "I've got yer back," that utilized the craft of needle felting to raise awareness and develop understanding of the anatomy of the human spine. The project took place in 2023 and engaged with participants from across the United Kingdom and abroad and its completion was timed to coincide with National Back Health Awareness week in October 2023. We describe the process of creating a vertebra using needle felt and examine how the particularities of the process and the use of the sense of touch helped participants notice and understand the complex form of the human vertebra. We consider how the project encompassed creative processes of hands‐on learning to enhance knowledge about this aspect of human anatomy. We discuss how the project evolved to include public and academic participation in a shared goal and argue for the effectiveness of seemingly simple and straightforward art or craft workshops in teaching relatively complex science. The article includes detailed feedback from participants who reflect on the process of learning through making and how it went on to affect individuals in very different, and sometimes very personal, ways. [ABSTRACT FROM AUTHOR]

Background: People with intellectual disabilities are rarely involved in research on quality of life. The study sought to answer the question: what do people with intellectual disabilities believe improves or hinders their quality of life? Method: Using an inclusive, accessible research design, 18 participants met in small groups to answer the study's question using their choice of arts‐based media. Participants completed the analysis collaboratively, identifying key themes among their responses. Results: The participants concluded that supports, well‐being, hobbies, and activities contribute to quality of life. Lack of accessibility, assumptions, negative behaviours, stress, and negative people (staff, roommates, people in general) were identified as detractors of quality of life. Conclusions: To continue to make progress in improving the quality of life of individuals with intellectual disabilities, the voice of those with intellectual disabilities is key. The results suggest key areas of focus to make these improvements. [ABSTRACT FROM AUTHOR]

In the history of Mongolian art, the beginning of modern painting is considered in connection with the "First Exhibition of Young Artists" in 1968. Although social-realist paintings developed at the beginning of the 20th century in line with the policies of the party and government, the colors and patterns of some artists' paintings were expressed with new thinking. In Mongolia, the development of modern art has been rapidly developing in recent years in the fields of Cubism, Impressionism, Surrealism, Abstract, and Expressionism, and dozens of works have been created. During this period, the artists and artists of our country kept pace with the global changes and innovations in the field of art studies, created new types of works of modern art, and continued to learn and develop new methods of theory and practice. Since 1990, Mongolia has transitioned from a centrally planned economic system to a market economic system, and individual ideals and freedom have increased not only in the industrial sector but also in the field of painting, and the direction of modern painting has begun to develop rapidly since then. In line with this, in addition to the public access to modern artworks, the need to read, understand, and explain their meaning and content has increased. Moreover, since 1990, the award for the best works of the year of the "Mongolian Art Gallery" has been won by works created in the genre of modern art, which indicates that this genre of art has taken a significant place in the history of Mongolian visual arts. Although modern paintings are being created in large numbers, there is a lack of research that evaluates and analyzes them from the point of view of art studies. In the works of some researchers, the subject of Mongolian modern painting became secondary research and was limited to mention, which is the reason for us to selectively study this topic. The purpose of the research is to analyze the development and classification of modern art of the late 20th and early 21st centuries, which are stored in art galleries. This study aims to create a trend of modernism or monalism that reflects Mongolian traditional thinking. [ABSTRACT FROM AUTHOR]

The article delves into the intersection of anthropology and literature, emphasizing how recent theoretical work has enriched the dialogue between these fields by exploring themes such as art, religion, subjectivity, and ethics, while also addressing methodological concerns. It highlights a series of conversations between fiction writer Siddratul Muntaha Jillani and anthropologist Kiran Nazir Ahmed, focusing on the parallels and contrasts between fiction writing and ethnographic writing.

Copyright of Theoria Journal for Philosophy / Theoria Casopis za Filozofiju is the property of Theoria Journal for Philosophy / Theoria Casopis za Filozofiju and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aesthetic experiences, emerging saliently in the arts, play a pivotal role in transformative learning and creative processes that elicit physiological, affective, and cognitive responses associated with mental health indices. Interactions between subjects and aesthetic objects (e.g., visual artwork, music, and moving bodies) often entail elements of surprise and uncertainty that drive the inference of the hidden causes in the subject's internal and external environment. These generate dynamics that align with the action-oriented Predictive Processing framework of brain function. Creative Arts Therapies (CATs) harness these dynamics by cultivating relational engagement using the arts modalities, prompting affective and cognitive processing. In this manuscript, we offer a review and conceptual analysis of recent empirical findings and theoretical premises that underpin aesthetic experiences and their relation to the psychotherapeutic use of the arts with a broad spectrum of populations and mental health conditions. We present a neuroscience-based approach to aesthetic intra- and inter-personal experiences, integrating therapeutic change factors of externalization-concretization, embodiment, and symbolization with functional network configurations, and interpersonal brain-to-brain coupling, to support predictive processing, learning, and creativity. Present and future interdisciplinary collaborations are underlined to elucidate the neurodynamic mechanisms driving psychological transformations, bridging neuroaesthetics and CATs. [ABSTRACT FROM AUTHOR]

Background: Antiretroviral therapy (ART) has transformed the life of PLHIV with a longer life expectancy. The rising coexistence of noncommunicable diseases (NCD)s especially type 2 diabetes mellitus (DM) and hypertension (HTN) among PLHIV (people living with HIV) is much more complicated and demanding for the health system, patients, and their families. To document the current status of type 2 DM and HTN among known diabetic/hypertensive PLHIV attending ART center, tertiary care hospital of South Gujarat. Materials and Methods: A mixed method study (cross-sectional survey followed by qualitative in-depth interview) was conducted among 184 PLHIV on ART with history of Type 2 DM and/or Hypertension who were registered and availing services from ART center, tertiary care hospital. Convenient sampling technique was used. All the participants were interviewed using pre-designed, semi-structured questionnaire, during their routine visits. In -depth interview (IDI) has been conducted to explore the delivery of NCD services at ART Centre. Results: Out of 184 PLHIV on ART, the most common co-morbidities were Type 2 DM (46.2%), HTN (39.13%), and 14.67% had both. Among total 184 participants, 64.1% were males and 35.9% were females. Only 22.3% of participants were availing treatment services for the above at tertiary care hospital. The study results showed a range of findings involving ART adherence, BMI, RBS, and BP measurements were included. IDI results described the NCD service delivery at ART Center. Conclusions: Study results suggest that the services received by PLHIV with NCD require an overhauling. Routine monitoring and strengthening of existing services should be focused to upgrade the quality and continuum of the care provided to PLHIV with NCD. [ABSTRACT FROM AUTHOR]

Objectives: This qualitative study aimed to comprehend the psychological well-beings and available interventions of current Chinese infertile patients, as well as investigate more integrated and effective patient support interventions, if necessary. Background: It is well known that infertility is a difficult struggle. Assisted reproductive technologies (ART) provide patients with the hope of having a child, but they also cause them pain and stress. There is a dearth of research on the mental health of infertile patients, particularly in developing nations such as China. Method: Individual interviews were conducted with eight experienced clinicians at the Reproductive Medicine Center from five different hospitals. On the basis of the grounded theory, interviews were transcribed and recursively analysed with the NVivo 12 Plus software by a research team. Results: 73 categories were created, which were then grouped into 12 subthemes that were combined to form the following themes: Theme I: Psychological Distress; Theme II: Sources of Distress; Theme III: Protective Factors; and Theme IV: Interventions. Conclusions: The themes of subjective experience identified in the study reveal infertile patients' emotional disturbance and resources of distress, consistent with previous related studies. Despite limitations such as the relatively small number of participants and the exclusively self-report nature of qualitative study, the findings of the study imply the importance of emotional and physical support networks for infertile patients at Reproductive Medicine Centers, consistency of psychological awareness and adequate professional supports. [ABSTRACT FROM AUTHOR]

Placental angiogenesis is a pivotal process for feto-maternal circulation and ensures efficient development of the placenta throughout pregnancy. Many factors during in vitro fertilization and embryo transfer procedures may affect placental gene expression and fetus development. The present study aimed to identify differences in angiogenesis-related gene (VEGFA, FGF2, FLT1, and KDR) expression profiles in placentas after assisted reproductive technology fertilization and natural conception in healthy women. In a case-control study, term placentas were collected from Caucasian women after assisted reproductive technology fertilization (N = 20) and after natural conception in women with uncomplicated pregnancy (N = 9). The mRNA expression in placentas was examined for VEGFA, FGF2, FLT1, and KDR genes by real-time quantitative polymerase chain reaction (RT-qPCR). Group stratification was performed for comparison of investigated genes between the type of embryo transferred (fresh/frozen), place of tissue donation (center/margin), and newborns' gender (male/female). In the ART placentas, significant down-regulation of VEGFA gene (p = 0.016) and up-regulation of FLT1 (p = 0.026) and KDR (p < 0.001) gene receptors were observed. Genes encoding VEGFA receptors were up-regulated in both fresh (ET) and frozen (FET) embryo transfer groups compared to controls. For the FLT1 gene, a statistically significant difference was observed between the frozen embryo transfer group and the controls (p = 0.032). Relative expression of KDR was significantly higher for both embryo transfer groups compared to controls (p < 0.001) and between ET and FET (p = 0.002). No statistically significant differences were observed between placental expression in different places of tissue donation and newborns' gender. We observed differences in the placental expression of VEGFA and its receptors FLT1 and KDR in pregnancies after assisted reproductive technology compared to naturally conceived pregnancies. More research is needed to clarify these alterations that may affect placental development and fetal health. [ABSTRACT FROM AUTHOR]

Copyright of Cuadernos del Centro de Estudios de Diseño y Comunicación is the property of Cuadernos del Centro de Estudios de Diseno y Comunicacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Adolescents and young adults (AYA) living with HIV have been shown to have lower rates of viral load testing and viral suppression as compared to older adults. We examined trends over time and predictors of HIV viral load monitoring and viral suppression among AYA in a large HIV treatment programme in Dar es Salaam, Tanzania. Methods: We analysed longitudinal data of AYA aged 10–24 years initiated on antiretroviral therapy between January 2017 and October 2022. Trend models were used to assess changes in HIV viral load testing and viral suppression by calendar year. Generalised estimating equations were used to examine the relationship of sociodemographic and clinical factors with HIV viral load testing and viral suppression. Results: Out of 15,759 AYA, the percentage of those who received a 6‐month HIV viral load testing increased from 40.6% in 2017 to 64.7% in 2022 and, a notable annual increase of 5.6% (p < 0.001). A higher HIV viral load testing uptake was observed among 20‐ to 24‐year‐olds (87.7%) compared to 10‐ to 19‐year‐olds (80.2%) (p < 0.001). The likelihood of not receiving an HIV viral load test within 12 months of antiretroviral therapy initiation was higher among 10‐ to 19‐year‐olds (adjusted odds ratio [aOR] = 1.7; 95% confidence interval [CI] = 1.4–2.0), advanced HIV disease (aOR = 1.3; 95% CI = 1.12–1.53), normal nutrition status at enrolment aOR 2.6 (95% CI = 1.59–4.26) and initiation of non‐nucleoside reverse transcriptase inhibitors regimen aOR 1.2 (95% CI = 1.08–1.34). The proportion of AYA with viral suppression increased from 83.0% in 2017 to 94.6% in 2022. Notably, the overall trend in viral suppression increased significantly at 2.4% annually. The risk of not achieving viral suppression was greater among 10‐ to 14‐year‐olds (aOR = 2; 95% CI = 1.75–2.43) and 15‐ to 19‐year‐olds (aOR = 1.4; 95% CI = 1.24–1.58) as compared to 20–24 years; being male (aOR = 1.16; 95% CI = 1.02–1.32); undernourished (aOR = 1.53; 95% CI = 1.17–1.99); in WHO Stage II (aOR = 1.16; 95% CI = 1.02–1.33) and III (aOR = 1.21; 95% CI = 1.03–1.42) and being on an non‐nucleoside reverse transcriptase inhibitors regimen (aOR = 1.32; 95% CI = 1.18–1.48). Conclusion: HIV viral load testing uptake at 6 months of antiretroviral therapy initiation and viral suppression increased from 2017 to 2022; however, overall HIV viral load testing was suboptimal. Demographic and clinical characteristics can be used to identify AYA at greater risk for not having HIV viral load test and not achieving viral suppression. [ABSTRACT FROM AUTHOR]

This essay recharacterizes Edward Weston, Paul Strand, and others' use of 'straight photography' as a deliberate modernist strategy that invites the viewer to distinguish between what the photographer foresaw in their photographs and what they intended. As such, 'previsualization' is shown to be a method that engages genre conventions inherited from fine art painting and not a necessary quality of art photographs. The first portion of this essay illustrates how versions of previsualization and foresight informed the aesthetic theories of John Ruskin and Peter Henry Emerson. Then, it shows how 'straight' photographers pushed against this tradition, inviting viewers to distinguish between photographic foresight and artistic intention. I conclude by suggesting ways the separation of foresight and intention could ramify into our understanding of other arts. [ABSTRACT FROM AUTHOR]

This chapter provides a close reading and critical analysis of work by two New York City-based Afro-Dominican artists, Joiri Minaya (1990) and Josefina Báez (1960). The author argues that Báez' "Carmen FotonovelARTE" (2020) and Minaya's "Containers" series (2015-2020) play with the trope of repose and mixed-race beauty to chart pathways of Afro-Latina representation that are shaped by yet that radically challenge the colonial script of the mulata. The artists create a space of refusal that transforms repose into a powerful site from which to articulate, problematize, and dismantle oppressive, reductive systems of representation. [ABSTRACT FROM AUTHOR]

The racialized gendered body in consumer culture invokes the construction of identities and representation of beauty through embodiment practices. As companies hone in on consumer racial marker distinctions to enhance uniqueness as otherness for profit, an analysis of hair products marketed for Black hair textures provides an opportunity to analyze how products use these at the intersection of race, gender, and beauty. This study uses constructivist grounded theory to analyze the product names and long descriptions for 124 shampoos marketed for Black hair textures on the websites of two major retailers to answer the following questions: What message does the discourse of shampoo product descriptions marketed to Black hair textures communicate about beauty? What message does the discourse of shampoo product descriptions marketed to Black hair textures communicate about Blackness? How does this discourse define the embodiment of Black beauty through hair? The results reveal that the racialized gendered body in consumer culture invokes the construction of identities and representations of beauty through embodiment practices. Through advertisements and product descriptions, beauty companies create ideal images of the lived experiences achieved through consuming beauty products. By constructing visual interpretations of racial signifiers through text, marketing strategies encourage the consumption of otherness, creating a racialized space for Blackness consumption. Combining the five senses with the descriptions of shampoo products marketed for Black hair textures helps us see how beauty embodiment practices reinforce racialized and gendered practices to subjugate the Black body. [ABSTRACT FROM AUTHOR]

The article examines the contested aspects of neoliberalism through cinematic narratives, addressing the issue of Assisted Reproductive Technology (ART) in India, a debated subject in socio-legal spheres. Existing literature extensively discusses the biopolitical and bioethical dimensions of commercialization and commodification, particularly concerning organ, egg, sperm donations, and gestational commercial surrogacy. This research endeavors to scrutinise and appraise the ethical quandaries emanating from the technological transformation of motherhood, as portrayed in fictional representations. These narratives shed light on the difficult situations faced by surrogates and egg donors, who are often driven by familial or socio-economic pressures to provide their reproductive services. Consequently, they become commodified within the context of India's In Vitro Fertilization (IVF) industry. Ergo, through the films I Am (2010) and Mimi (2021), this article probes into the intertwining socioeconomic situations of the large percentage of infertile women and claims that the positive discourse around the 'new Indian women' is inherently diluted and undermined. Additionally, the research emphasizes that ART—and more importantly, a new agency for single women—is reiterated within the political and socio-historical contexts of the films discussed. [ABSTRACT FROM AUTHOR]

Can art illuminate life or is it just so much irrelevant illusion (or delusion)? Certainly, Plato—the great founding father of Western philosophy—seems to have been largely drawn to the latter view. From Plato onwards, however, this more sceptical perspective seems bedevilled by a range of conceptual conflations and confusions regarding the language and purposes of art. Proceeding by way of critical attention to distinctions between (for example) imagination and fantasy and the artistic and the aesthetic and to the different cognitive and affective functions of literal and figurative usage, this article also draws upon diverse insights of poets and artists to argue that the ultimate purpose of the deliberate or "artificial" separation of significant art from "real" human life is nevertheless to enable deeper perception and appreciation of that life. [ABSTRACT FROM AUTHOR]

This article focuses on the experience of unsettling art and its psychological impact. Although it is widely recognized that works of art can be highly unsettling and disturbing, there seem to be no studies revealing the psychological importance of such experiences. Through a selection of interviews conducted according to phenomenological principles, a few essential features of the unsettling art experience are identified. These features include a strong negative emotional response, feelings of attraction, and pictorial vividness. Furthermore, these experiences form memory traces that are powerful, persistent, and long-lasting. The present study shows that when experiencing an unpleasant emotional response to a work of art, the emotion is linked to the sensate form of the picture and thereby objectified, allowing contemplation of the existential importance of the experience. Furthermore, this study uncovers a possible relation between prior traumatic episodes and an intense emotional response to unsettling art, and it is suggested that experiences with unsettling works of art allow the individual to reconcile with their prior trauma. [ABSTRACT FROM AUTHOR]

Background: Insulin resistance (IR) is related with adverse outcomes of in vitro fertilization (IVF) in women with obesity, but little is known about the relationship between IR and unexpected poor ovarian response (uPOR) in non-obese subjects with sufficient ovarian parameters (classified as POSEIDON group 1). This research aims to explore the association between the homeostasis model assessment of insulin resistance (HOMA-IR) and uPOR in non-obese women with normal biomarkers of ovarian reserve. Methods: The retrospective cohort study was conducted at a fertility center. The main inclusion criteria were age < 35 years, body mass index (BMI) < 28 kg/m2, normal ovarian reserve (anti-Mullerian hormone ≥ 1.2 ng/ml, antral follicle count ≥ 5). Women undergoing the first oocyte retrieval cycle were included consecutively between 2018 until 2023. Patients who have ≤ 9 oocytes retrieved were defined as uPOR. The multivariable logistic model and subgroup analysis were conducted after adjusting confounders. Results: A total of 6977 cycles were included. The adjusted odds ratio was 1.25 (95% confidence interval [CI], 1.12–1.39) for the increment of Ln HOMA-IR which was taken as a continuous variable. Meanwhile, as a sensitivity analysis, elevated tertile of HOMA-IR exhibited an increase in risk of uPOR for the third tertile (≥ 2.75) when compared with the first tertile (< 1.75) with OR of 1.33 (95%CI, 1.15–1.54). In the subgroup analysis, the positive association remained consistent. Conclusion: Elevated HOMA-IR values is significantly associated with increased risk of uPOR in non-obese women classified as POSEIDON group 1. Our study provided evidence for the adverse influence of IR on the ovarian response during IVF and shed light on the importance of IR measurement at the time of pre-stimulation among non-obese women. [ABSTRACT FROM AUTHOR]

Background: Echocardiography can be used to screen, confirm, and assist in the management of some cardiovascular diseases in people living with human immunodeficiency virus (HIV) (PLWH). Thus, complications from subclinical cardiovascular conditions or more apparent conditions, such as massive pericardial effusion with tamponade, can be promptly identified and managed to minimize cardiovascular morbidity and mortality associated with HIV infection. Since the introduction of antiretroviral therapy (ART) in Ghana approximately two decades ago, studies on the prevalence and patterns of echocardiographic abnormalities among PLWH on ART have been limited. This study was designed to assess the prevalence and patterns of echocardiographic abnormalities among PLWH on ART. Methods: This was a cross-sectional study. PLWH on ART (cases) attending the HIV clinic at Komfo Anokye Teaching Hospital (KATH) and HIV-negative blood donors (controls) were consecutively recruited and enrolled in this study. The interviews were performed via a standardized questionnaire. After a clinical examination was performed, all patients underwent two-dimensional (2D) and Doppler transthoracic echocardiograms. The prevalence and patterns of echocardiographic abnormalities were characterized. Results: There were 117 patients in each arm of the study. There were more females than males among both the cases (92 (78.6%) and controls (80 (68.4%)); however, the sex distribution was similar between the two groups (p = 0.075). For clinical characteristics such as age, weight, height and blood pressure, there were no statistically significant differences between the cases and controls. Echocardiographic abnormalities were more frequently observed and demonstrated a statistically significant difference between cases and controls, with an overall prevalence of 35.0% among cases and 19.7% among controls (p = 0.008). The echocardiographic abnormalities that demonstrated significant differences between the cases and controls were left ventricular (LV) diastolic dysfunction (28.2% versus 8.6%; p = 0.000) and LV hypertrophy (7% versus 0.9%; p = 0.017). Conclusion: Nearly 1 in 3 PLWH on ART had an echocardiographic abnormality in this Ghanaian study. Echocardiograms are recommended as helpful screening modalities for diagnosing cardiac abnormalities among PLWH on ART. [ABSTRACT FROM AUTHOR]

Introduction: Long-acting injectable antiretroviral treatment (LAI-ART) has emerged as a novel alternative to the burden of daily oral pills. The bi-monthly intramuscular injectable containing cabotegravir and rilpivirine holds the promise of improving adherence to ART. The perspectives of potential users of LAI-ART, the majority of whom reside in Eastern and Southern Africa, are still largely unexplored. We set out to understand the experiences of people with HIV (PWH) who received LAI-ART at Fort Portal Regional Referral Hospital in mid-Western Uganda for at least 12 months. Methods: This qualitative study, conducted between July and August 2023, was nested within a larger study. We conducted four focus groups with 32 (out of 69) PWH who received intramuscular injections of cabotegravir and rilpivirine. In-depth interviews were held with six health workers who delivered LAI-ART to PWH. Data were analyzed by thematic approach broadly modeled on the five domains of the Consolidated Framework for Implementation Research (CFIR). Results: There was high acceptability of LAI-ART (30 /32 or 94%) participants requested to remain on LAI-ART even after the end of the 12-month trial. Adherence to ART was reportedly improved when compared to daily oral treatment. Participants credited LAI-ART with; superior viral load suppression, redemption from the daily psychological reminder of living with HIV, enhanced privacy in HIV care and treatment, reduced HIV-related stigma associated with taking oral pills and that it absolved them from carrying bulky medication packages. Conversely, nine participants reported pain around the injection site and a transient fever soon after administering the injection as side effects of LAI-ART. Missed appointments for receiving the bi-monthly injection were common. Providers identified health system barriers to the prospective scale-up of LAI-ART which include the perceived high cost of LAI-ART, stringent cold chain requirements, physical space limitations, and workforce skills gaps in LAI-ART delivery as potential drawbacks. Conclusion: Overall, PWH strongly preferred LAI-ART and expressed a comparatively higher satisfaction with this treatment alternative. Health system barriers to potential scale-up are essential to consider if a broader population of PWH will benefit from this novel HIV treatment option in Uganda and other resource-limited settings. Trial registration: Trial Registry Number PACTR ID PACTR202104874490818 (registered on 16/04/2021). [ABSTRACT FROM AUTHOR]

Art and artistic creation serve as a means for artists to communicate with their environment, society, and the external world. However, the protection of artistic creations, as forms of communication, is not only a right for artists but also serves as a crucial safeguard that nurtures them during the creative process. Beyond the traditional issues of copyright, the significant advancements in Artificial Intelligence (AI) in today's digital world have introduced a new debate regarding the ownership of copyright in artistic creations generated by AI. The question arises whether copyright belongs to the AI itself or to the individuals who guide the creative process behind it. In this study, based on the concepts of art, artistic creation, and emotional states, copyright issues will be examined. Data obtained from semi-structured in-depth interviews with artists and academic experts (eight artists, two communication experts, two law experts, and eight psychology experts) in the field will be analysed through content analysis to explore their perspectives regarding the discussion on emotional states, AI, and copyrights. The research highlights the variability of emotional states and their significant effects on individuals. Addressing the increasing trend of copyright issues, particularly within the framework of digitalization and inadequate legal regulations, it was found that artists' emotional states are negatively impacted by these problems. This negative influence can adversely affect artists' creativity and desire to produce. On the other hand, it was also identified that in artworks produced especially through AI, if artists' rights are not protected, there is a possibility of negative emotional states arising. In conclusion, suggestions are as follows: Emphasising the importance of awareness-raising educational activities nationally and internationally, national copyright law (in Northern Cyprus) needs to be revised to protect traditional copyright and be expanded to include digital copyright, especially for works produced through AI. On an international level, emphasising the need to revise international agreements to include regulations for works produced through AI or to create a new agreement based on the importance of this issue. [ABSTRACT FROM AUTHOR]

In this paper, we discuss the requirements and technical challenges within the EHEM project, Enhancement of Heritage Experiences: The Middle Ages, an ongoing research program for the acquisition, analysis, documentation, interpretation, digital restoration, and communication of medieval artistic heritage. The project involves multidisciplinary teams comprising art historians and visual computing experts. Despite the vast literature on digital 3D models in support of Cultural Heritage, the field is so rich and diverse that specific projects often imply distinct, unique requirements which often challenge the computational technologies and suggest new research opportunities. As good representatives of such diversity, we describe the three monuments that serve as test cases for the project, all of them with a rich history of architecture and paintings. We discuss the art historians' view of how digital models can support their research, the expertise and technological solutions adopted so far, as well as the technical challenges in multiple areas spanning geometry and appearance acquisition, color analysis and digital restitution, as well as the representation of the profound transformations due to the alterations suffered over the centuries. [ABSTRACT FROM AUTHOR]