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More than 60% newborns experience hyperbilirubinemia and jaundice within the initial week after birth due to the accumulation of total bilirubin in blood. Left untreated high levels of bilirubin may result in brain impairment. Simple, fast, accurate, low-cost and timely point-of-care (POC) analysis of total bilirubin is an unmet need especially in resource-limited areas. This work introduces a novel sensing device, named a "tape-paper sensor", capable of separating plasma from whole blood and measuring total bilirubin by a colorimetric diazotization method. The tape-paper sensing method overcomes non-homogeneous color distribution caused by the "coffee stain" effect, which improves the accuracy of colorimetric evaluation on paper-based analytical devices. The level of hemolysis in the plasma extracted by the device is evaluated, confirming no interference in the detection of total bilirubin. The accuracy of the tape-paper sensing approach for neonatal blood sample measurement is verified by comparison with the hospital pathology laboratory method. The small volume of samples and reagents, minimal equipment (an office scanner), fast detection (<10 min) and low fabrication cost (~A$ 0.6) reveal the suitability of the device for POC use and in resource-limited settings. The tape-paper sensor is a low-cost, fast, and user-friendly device for measurement of blood total bilirubin levels in neonatal jaundice diagnostics.Copyright © 2020 The Royal Society of Chemistry.

More than 60% newborns experience hyperbilirubinemia and jaundice within the initial week after birth due to the accumulation of total bilirubin in blood. Left untreated high levels of bilirubin may result in brain impairment. Simple, fast, accurate, low-cost and timely point-of-care (POC) analysis of total bilirubin is an unmet need especially in resource-limited areas. This work introduces a novel sensing device, named a "tape-paper sensor", capable of separating plasma from whole blood and measuring total bilirubin by a colorimetric diazotization method. The tape-paper sensing method overcomes non-homogeneous color distribution caused by the "coffee stain" effect, which improves the accuracy of colorimetric evaluation on paper-based analytical devices. The level of hemolysis in the plasma extracted by the device is evaluated, confirming no interference in the detection of total bilirubin. The accuracy of the tape-paper sensing approach for neonatal blood sample measurement is verified by comparison with the hospital pathology laboratory method. The small volume of samples and reagents, minimal equipment (an office scanner), fast detection (<10 min) and low fabrication cost (~A$ 0.6) reveal the suitability of the device for POC use and in resource-limited settings. The tape-paper sensor is a low-cost, fast, and user-friendly device for measurement of blood total bilirubin levels in neonatal jaundice diagnostics.Copyright © 2020 The Royal Society of Chemistry.

Y. Huang, Y. Morishita, K. Uetani, M. Nogi and H. Koga. Cellulose paper support with dual-layered nano–microstructures for enhanced plasmonic photothermal heating and solar vapor generation. Nanoscale Adv., 2020, 2, 2339. https://doi.org/10.1039/D0NA00163E., Plasmonic nanoparticles, such as gold nanoparticles (AuNPs), have been actively applied in solar vapor generation for seawater desalination and water purification, owing to their photothermal heating performances. Such nanoparticles have been frequently anchored within porous supporting materials to ensure easy handling and water absorption. However, there has been limited progress in improving the transport efficiency of light to nanoparticles within porous supports to achieve more effective photothermal heating. Here, we show an enhanced light absorption of AuNPs by supporting on a cellulose paper with tailored porous structures for efficient photothermal heating. The paper consists of AuNP-anchored cellulose nanofibers and cellulose pulp as the top and bottom layers, respectively, which provides dual-layered porous nano-microstructures in the perpendicular direction. Then, the bottom layer with pulp-derived microstructures reflects the transmitted light back to AuNPs within the top layer, which improves their light absorptivity. Thus, under 1 sun illumination, the dual-layered paper demonstrates superior performance in photothermal heating (increases from 28 °C to 46 °C) and solar vapor generation (1.72 kg m-2 h-1) compared with the single-layered AuNP-anchored cellulose nanofiber paper even at the same AuNP content. Furthermore, the water evaporation rate per AuNP content of the dual-layered paper is more than 2 times higher than those of the state-of-the-art AuNP-anchored porous materials under the same light irradiation. This strategy enables the efficient use of precious plasmonic nanoparticles for further development of solar vapor generation.

In this study, we report for the first time few-layered MoS2 nanosheets grown onto graphene dipped cellulose filter paper (M-G-CFP) using a simple hydrothermal method towards efficient adsorption of cationic methylene blue (MB) dye. Detailed morphological and chemical characterization studies of M-G-CFP are performed using FESEM, TEM, XRD and Raman spectroscopy that reveal micro flower-like MoS2 grown onto graphene modified paper with few layers of MoS2 nanosheets and its high purity nature. Due to electrostatic interactions between cationic dye and the anionic adsorbent surface, the hybrid M-G-CFP exhibits ultrafast removal of MB within 2 min with a maximum adsorption capacity of 485.4 mg g-1 which is superior in comparison to other reported MoS2 based adsorbents. This high adsorption capacity is attributed to large accessible active sites on the surface of the hybrid M-G-CFP structure. The adsorption mechanism of MB dye on the MoS2 nanosheets are well described using kinetic and isotherm models with the effects of parameters like pH, contact time and temperature. The kinetic and isotherm study reveals that the adsorption of MB dye follows a pseudo-second order model, indicating the chemisorption and Langmuir model of monolayer adsorption, respectively. Furthermore, this hybrid structure can be efficiently reused for subsequent dye adsorption without compromising on its dye removal efficiency suggesting it is a feasible and promising material towards wastewater treatment applications.

In this study, we report for the first time few-layered MoS2 nanosheets grown onto graphene dipped cellulose filter paper (M-G-CFP) using a simple hydrothermal method towards efficient adsorption of cationic methylene blue (MB) dye. Detailed morphological and chemical characterization studies of M-G-CFP are performed using FESEM, TEM, XRD and Raman spectroscopy that reveal micro flower-like MoS2 grown onto graphene modified paper with few layers of MoS2 nanosheets and its high purity nature. Due to electrostatic interactions between cationic dye and the anionic adsorbent surface, the hybrid M-G-CFP exhibits ultrafast removal of MB within 2 min with a maximum adsorption capacity of 485.4 mg g-1 which is superior in comparison to other reported MoS2 based adsorbents. This high adsorption capacity is attributed to large accessible active sites on the surface of the hybrid M-G-CFP structure. The adsorption mechanism of MB dye on the MoS2 nanosheets are well described using kinetic and isotherm models with the effects of parameters like pH, contact time and temperature. The kinetic and isotherm study reveals that the adsorption of MB dye follows a pseudo-second order model, indicating the chemisorption and Langmuir model of monolayer adsorption, respectively. Furthermore, this hybrid structure can be efficiently reused for subsequent dye adsorption without compromising on its dye removal efficiency suggesting it is a feasible and promising material towards wastewater treatment applications.

In this study, we report for the first time few-layered MoS2 nanosheets grown onto graphene dipped cellulose filter paper (M-G-CFP) using a simple hydrothermal method towards efficient adsorption of cationic methylene blue (MB) dye. Detailed morphological and chemical characterization studies of M-G-CFP are performed using FESEM, TEM, XRD and Raman spectroscopy that reveal micro flower-like MoS2 grown onto graphene modified paper with few layers of MoS2 nanosheets and its high purity nature. Due to electrostatic interactions between cationic dye and the anionic adsorbent surface, the hybrid M-G-CFP exhibits ultrafast removal of MB within 2 min with a maximum adsorption capacity of 485.4 mg g-1 which is superior in comparison to other reported MoS2 based adsorbents. This high adsorption capacity is attributed to large accessible active sites on the surface of the hybrid M-G-CFP structure. The adsorption mechanism of MB dye on the MoS2 nanosheets are well described using kinetic and isotherm models with the effects of parameters like pH, contact time and temperature. The kinetic and isotherm study reveals that the adsorption of MB dye follows a pseudo-second order model, indicating the chemisorption and Langmuir model of monolayer adsorption, respectively. Furthermore, this hybrid structure can be efficiently reused for subsequent dye adsorption without compromising on its dye removal efficiency suggesting it is a feasible and promising material towards wastewater treatment applications.

In this study, we report for the first time few-layered MoS2 nanosheets grown onto graphene dipped cellulose filter paper (M-G-CFP) by a simple hydrothermal method towards efficient adsorption of cationic methylene blue (MB) dye. Detailed morphological and chemical characterization studies of M-G-CFP are performed using FESEM, TEM, XRD and Raman spectroscopy that reveal micro flower-like MoS2 grown onto graphene modified paper with few layers of MoS2 nanosheets and its high purity nature. Due to electrostatic interaction between cationic dye and anionic adsorbent surface, the hybrid M-G-CFP exhibits ultrafast removal of MB within 2 min with maximum adsorption capacity of 485.4 mg/g which is superior in comparison to other reported MoS2 based adsorbents. This high adsorption capacity is attributed to the large accessible active sites on the surface of hybrid M-G-CFP structure. The adsorption mechanism of MB dye on MoS2 nanosheets are well described using kinetic and isotherm models with the effects of parameters like pH, contact time and temperature. The kinetic and isotherm study reveals that the adsorption of MB dye follows pseudo-second order model, indicating the chemisorption and Langmuir model of monolayer adsorption, respectively. Furthermore, this hybrid structure can be efficiently reused for subsequent dye adsorption without compromising on its dye removal efficiency suggesting a feasible and promising material towards waste-water treatment applications.

In this study, we report for the first time few-layered MoS2 nanosheets grown onto graphene dipped cellulose filter paper (M-G-CFP) using a simple hydrothermal method towards efficient adsorption of cationic methylene blue (MB) dye. Detailed morphological and chemical characterization studies of M-G-CFP are performed using FESEM, TEM, XRD and Raman spectroscopy that reveal micro flower-like MoS2 grown onto graphene modified paper with few layers of MoS2 nanosheets and its high purity nature. Due to electrostatic interactions between cationic dye and the anionic adsorbent surface, the hybrid M-G-CFP exhibits ultrafast removal of MB within 2 min with a maximum adsorption capacity of 485.4 mg g-1 which is superior in comparison to other reported MoS2 based adsorbents. This high adsorption capacity is attributed to large accessible active sites on the surface of the hybrid M-G-CFP structure. The adsorption mechanism of MB dye on the MoS2 nanosheets are well described using kinetic and isotherm models with the effects of parameters like pH, contact time and temperature. The kinetic and isotherm study reveals that the adsorption of MB dye follows a pseudo-second order model, indicating the chemisorption and Langmuir model of monolayer adsorption, respectively. Furthermore, this hybrid structure can be efficiently reused for subsequent dye adsorption without compromising on its dye removal efficiency suggesting it is a feasible and promising material towards wastewater treatment applications.

H and 13C NMR spectra

Herein we present a novel sensor for the detection of monosaccharides (e.g. glucose, fructose) in solution, using electrical impedance spectroscopy. The sensor is based on carbon interdigitated electrodes, printed on paper using screen printing. The surface of the electrodes was modified with a thin layer of hydrogel containing acrylamide copolymerised with 20 mol% 3-(Acrylamido)phenylboronic acid (PBA). It was observed that the hydrogel layers containing 20 mol% PBA swell considerably in the presence of glucose and fructose. This in turn changes the measured impedance across the electrodes, making it a suitable sensor for the quantitative detection of saccharides. We investigated the impedance and capacitance variations with different concentrations of glucose and fructose (0–5 mM) in aqueous phosphate buffer solutions. Variations in impedance were attributed to changes in the dielectric properties of the hydrogel under an applied electric field, due to swelling of the hydrogel layer induced by uptake and binding of sugar molecules to the boronate species within the gel. Impedance measurements at 1 kHz demonstrated that hydrogel swelling leads to an increased mobility of ions within the swollen hydrogel layer. The impedance decreased with increasing sugar concentration and the relative capacitance curves are markedly different for fructose and glucose, as the hydrogel exhibits greater swelling in the presence of fructose than glucose over the same concentration range. As the proposed sensor was shown to be suitable for the detection of glucose at concentration levels found in human sweat, future work will focus on the incorporation of these modified paper-based electrodes into wearable skin patches for non-invasive sugar monitoring in sweat.

Herein we present a novel sensor for the detection of monosaccharides (e.g. glucose, fructose) in solution, using electrical impedance spectroscopy. The sensor is based on carbon interdigitated electrodes, printed on paper using screen printing. The surface of the electrodes was modified with a thin layer of hydrogel containing acrylamide copolymerised with 20 mol% 3-(Acrylamido)phenylboronic acid (PBA). It was observed that the hydrogel layers containing 20 mol% PBA swell considerably in the presence of glucose and fructose. This in turn changes the measured impedance across the electrodes, making it a suitable sensor for the quantitative detection of saccharides. We investigated the impedance and capacitance variations with different concentrations of glucose and fructose (0–5 mM) in aqueous phosphate buffer solutions. Variations in impedance were attributed to changes in the dielectric properties of the hydrogel under an applied electric field, due to swelling of the hydrogel layer induced by uptake and binding of sugar molecules to the boronate species within the gel. Impedance measurements at 1 kHz demonstrated that hydrogel swelling leads to an increased mobility of ions within the swollen hydrogel layer. The impedance decreased with increasing sugar concentration and the relative capacitance curves are markedly different for fructose and glucose, as the hydrogel exhibits greater swelling in the presence of fructose than glucose over the same concentration range. As the proposed sensor was shown to be suitable for the detection of glucose at concentration levels found in human sweat, future work will focus on the incorporation of these modified paper-based electrodes into wearable skin patches for non-invasive sugar monitoring in sweat.

The nematic structuring of cellulose nanofibers (CNFs) is proposed as a nanostructural engineering tool for exploiting the potential of CNFs in conceptually new "transparent papers". The nematic-structured CNF papers exhibit superior mechanical properties, optical transparency, gas-barrier properties, heat transfer properties and electrical resistivity, compared with conventional randomly-structured CNF papers., Non-duplicate with ISI: 000435537702500QC 20180227