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1. Computational design of the temperature optimum of an enzyme reaction.

Author

van der Ent, Florian, Skagseth, Susann, Lund, Bjarte A., Sočan, Jaka, Griese, Julia J., Brandsdal, Bjørn O., and Åqvist, Johan

Abstract

The article discusses the computational design of the temperature optimum for an enzyme reaction. Topics include the characteristics of cold-adapted enzymes, the inactivation of enzymes at temperatures other than protein melting and the successful redesign of an α-amylase enzyme to shift its temperature optimum.

Published
2023
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