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The simple microscope was for a long time the best instrument to scrutinize the microscopic world. Its quality is greater than what is usually assumed and it allows the observation of almost all structures that are seen with a modern compound microscope. We will explain how to build a powerful simple microscope with more than 400 magnification, using a microsphere lens. [ABSTRACT FROM AUTHOR]

This article shows us how from the experiences shared with the Master Daniel Herrera, phenomenology is not far from being a job in which the philosopher details the life-world as if it were an encrypted text that demands the phenomenological reflection, as if it were a magni- fying glass in the hands of a rigorous reader. The text recalls the visits of Professor Juan Cepeda to the home of Master Daniel Herrera, and how he would answer his concerns making use of a magnifying glass to assist his reading. [ABSTRACT FROM AUTHOR]

The domestic dog offers a unique opportunity to explore the genetic basis of disease, morphology and behaviour. Humans share many diseases with our canine companions, making dogs an ideal model organism for comparative disease genetics. Using newly developed resources, genome-wide association studies in dog breeds are proving to be exceptionally powerful. Towards this aim, veterinarians and geneticists from 12 European countries are collaborating to collect and analyse the DNA from large cohorts of dogs suffering from a range of carefully defined diseases of relevance to human health. This project, named LUPA, has already delivered considerable results. The consortium has collaborated to develop a new high density single nucleotide polymorphism (SNP) array. Mutations for four monogenic diseases have been identified and the information has been utilised to find mutations in human patients. Several complex diseases have been mapped and fine mapping is underway. These findings should ultimately lead to a better understanding of the molecular mechanisms underlying complex diseases in both humans and their best friend. [ABSTRACT FROM AUTHOR]