1. Treatment of Acute Lymphoid Leukemia Refractory to Classic First-Line and Rescue Protocols.
- Author
-
Tobaldini Russo, Flávia, de Almeida Macedo, Maria Cristina Martins, Amoedo Fernades, Pedro, Okada, Larissa Yukari, da Silva, Lucas Augusto Monetta, Menin Simões, Camila, Cavalcante, Jamilla Neves, de Almeida Simões, Aline, de Souza Sampaio Almeida, Manuella, Ferreira Lopes, Maricy Almeida Viol, and da Silva, Roberto Luiz
- Subjects
- *
LYMPHOCYTIC leukemia , *ACUTE leukemia , *BORTEZOMIB , *LYMPHOBLASTIC leukemia - Abstract
Acute Lymphoblastic Leukemia is a very aggressive malignant disorder of lymphoid cells in adults, with recurrence (30 to 60% of the cases) after the initial treatment. Until this moment, there is no gold standard therapy for the treatment of adult patients with acute relapsed/refractory lymphoblastic leukemia. In this case report, we describe two cases of relapsed leukemia: one of lymphocytic leukemia B and one of trilineage leukemia, which presented a satisfactory response to treatment with Bortezomib associated with Vincristine, Dexamethasone, and Bendamustine. [ABSTRACT FROM AUTHOR]
- Published
- 2020