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Because people nowadays are addicted to eating too much fat, sweet food with thick taste, the incidence of stroke with damp-heat pattern is constantly increasing ・ Through combing the theoretical connotation and origins of u turbidity, u clear orifice", and u turbid evil invading the clear orifice", this article clarifies that damp heat is an important cause that cannot be ignored in the occurrence and development of stroke・ The causes of dampinclude external contraction and internal injury・ Dampheat obstructs the qi movement in the middle jiao, and blocks clear orifice in the upper part of the body, leading to the symptoms of the head and face, and even inducing the occurrence of stroke. Ye Tianshi5 s theory of u turbid evil invading the clear orificecan be regarded as a general exposition of u damp-heat leading to stroke ", so the diagnosis, treatment and prevention of damp-heat pattern should be emphasized ・ Based on the hypothesis of u brain-intestine interlink age, the core organs affected for the disease of stroke with damp-heat pattern are the brain, spleen, stomach and intestine・ To prevent stroke due to damp - heat, the above ・HientiorLe(l organs should be addressed by clearing dampness and heat, unblocking the fu organs and clearing orifices・ The theory of u turbid evil invading the clear orificeand the above-mentioned therapeutic methods are all derived from the theory and treatment experience of febrile disease・ Besides, therapies such as "differentiating and dispelling pathogenic factors from the three jiao" and u nourishing yin and promoting generation of body fluids" are also used in the treatment of stroke・ Therefore, the theory and experience of febrile disease may provide new ideas and methods for the prevention and treatment of stroke・ [ABSTRACT FROM AUTHOR]

Chronic ideopathic pruritus is an itch originating from unknown sources that lasts greater than six weeks. A 30-year-old female reported a chief complaint of chronic idiopathic pruritus. From a traditional Chinese medicine perspective she displayed signs and symptoms consistent with Spleen qi deficiency with accumulation of Damp-Heat, Liver qi stagnation and Blood deficiency leading to deficient and stagnant Heat stirring Wind. She had been previously seen by an internist, four dermatologists, two neurologists, and an allergist at the Mayo Clinic, showing inconclusive results of all biomedical tests. While there were clear pathophysiological mechanisms within traditional Chinese medicine that affected this case, the patient was unusually slow to respond to treatment. Careful case management and the introduction of traditional Chinese dietary considerations ultimately proved to be an effective intervention for this patient. This case history shows the need for further research to determine efficacy and establish effective mechanisms of action for treatment of this condition. [ABSTRACT FROM AUTHOR]

• Consumer type multicrystalline modules are investigated in two types of conditions: thermal cycle and damp heat testing. • Visual inspection, thermography, electroluminescence and IV-curve measurement help us for the investigation. • The results show that, corrosion, hot spot and delamination are the main degradation observed. In this study, consumer type multicrystalline modules are investigated. To assess the long-term reliability of photovoltaic (PV) multicrystalline modules, extended thermal cycling and damp heat testing were performed. This study focused on four multicrystalline modules. Two modules were subjected to 85 °C/85% damp heat testing at 1000 h and 1300 h, respectively. The other two modules were subjected to thermal cycle test of 55 cycles and 66 cycles, respectively. After testing, all 4 solar panels were investigated with the help of visual inspection, thermography, electroluminescence and IV-curve measurements. The main degradations observed were corrosion, hot spot and delamination. [ABSTRACT FROM AUTHOR]

Acquired female infertility from a traditional Chinese veterinary medical (TCVM) perspective can be associated with Deficiency or Excess patterns. There are 6 patterns of acquired female infertility commonly diagnosed in TCVM practice. The 6 patterns are: 1) Kidney Qi and Blood Deficiency, 2) Kidney Yin Deficiency, 3) Kidney Yang Deficiency or Cold uterus, 4) Excess Phlegm and Damp, 5) Liver Qi and Blood Stagnation and 6) Damp-Heat. Malnutrition or over-working can result in infertility from Kidney Qi and Blood Deficiency or Kidney Yin Deficiency. Obesity will cause Stagnation in the uterus with an Excess of Phlegm and Damp, making it impossible for oocytes to be released or connect with sperm. Cold Deficiency of the uterus or Kidney Yang Deficiency will damage the Chong Channel and the Conception Vessel (Ren Channel) and lead to infertility. Stagnant Qi and Blood in the Liver can impair uterine reproductive function and lead to infertility. Damp-Heat flows downward to the uterus and infertility results. Each pattern has characteristic findings on the TCVM examination, may require treatment of different acupoints and most importantly require different Chinese herbal medicines. Administering the incorrect Chinese herbal medicine could worsen the problems and harm the animal. Thus, when diagnosing infertility, one should attempt to identify the correct pattern, so that proper treatment can be administered. The pathogenesis, clinical signs, treatment principles, acupuncture points and Chinese herbal medicines are described for each pattern. Infertility due to congenital defects and aging are not discussed. [ABSTRACT FROM AUTHOR]

Scutellaria baicalensis (S. baicalensis) is the root of S. baicalensis Georgi. In traditional Chinese medicine it is divided into Tiaoqin (TQ, 1–3 years old) and Kuqin (KQ, more than 3 years old). However, the differences in TQ and KQ efficacy and their exact mechanisms are still unclear. This study aimed to clarify the difference in the efficacy of TQ and KQ in relation to different fever types (damp heat and hyperpyrexia) by using rat models, as well as to determine the primary molecular mechanism. This study compared the compositional content of TQ and KQ by UPLC-MS/MS. Then, rat models of hyperpyrexia (HP, LPS) and damp heat (DH, high-fat and high-sugar diet feeding + fumigation in artificial climate chamber + E. coli injection) were established and their clinical symptoms, blood biochemistry, histopathological sections, cell cytokines and protein expression were compared following treatment with TQ or KQ. Finally, the mechanisms underpinning the differences observed for TQ and KQ were determined by measuring the components of these treatments in different target organs. This study identified 31 compounds in the water extracts of both TQ and KQ, which differed significantly in their relative content. TQ and KQ showed different functional tropism in HP and DH model rats. Baicalin, wogonoside, oroxin A, baicalein, wogonin and oroxylin A appeared to be the basic functional components responsible for the functional tropism hypothesis, while the remaining compounds appeared to be the efficacy-oriented components. In addition, the difference in pharmacodynamics between TQ and KQ may be related to their absorption in vivo , which was consistent with the hypothesis of functional tropism proposed in this work. In this study we adopted TQ and KQ―different specifications of Scutellaria baicalensis with similar chemical components―as a case study to systematically reveal the functional tropism of Chinese herbal medicine (CHM). The results showed that TQ and KQ contain the basic functional components to enable the basic function of 'clearing heat', while the variation in compositional content may result in their different therapeutic effects. A greater understanding and utilisation of the functional tropism of CHM would enormously improve the accuracy and scientific basis for the application of CHM medication, as well as in promoting the multi-function mechanism of CHM and guiding new drug development of CHM. This work is based on the difference between TQ and KQ in efficacy and clinical usage in traditional Chinese medicine. Current research of this work provides new ideas for the development of TQ and KQ. Image 1 [ABSTRACT FROM AUTHOR]