Search

Accurate and quantifiable detection of the specific wavelength is vital in different application scenarios. Herein, a novel self‐driven narrowband photodetector (NB‐PD) based on CH(NH2)2PbBr2.5I0.5 crystal film is employed for building a yellow light intensity meter. By taking advantage of the carrier collection narrowing mechanism, a sensitive NB‐PD with peak response at 580 nm and the full‐width at half‐maximum of 23 nm are successfully achieved. The asymmetric contact electrodes of Ag/Pt allow the device to work without bias. The optoelectronic analysis demonstrates that the NB‐PD achieves a maximum responsivity of 59.89 mA W−1, a fast response speed of 202/331 µs, and a high on/off ratio of 636 at zero bias. Then, through introducing the back‐end circuit, a yellow light intensity meter is constructed with the NB‐PD. The absolute error and relative error of the light meter are estimated to be lower than 0.08 mW cm−2 and 4.22%, respectively, indicating the good capability for the yellow light monitoring. Given the simple device geometry and good performance, the achieved yellow light intensity meter can also be extended to other narrowband light detection system. [ABSTRACT FROM AUTHOR]

Free-standing Pt–Ni nanowires were fabricated by a one-pot solvothermal method. Nanowires with an optimal Pt/Ni ratio of 1.86 exhibited a high activity and a 100% H2 selectivity for hydrous hydrazine decomposition at mild temperatures, which are comparable to the levels of supported catalysts. Our study reveals for the first time that basic support is not a prerequisite for achieving favorable catalytic performance and provides a renewed perspective for the design of advanced catalysts for on-demand H2 generation from hydrous hydrazine. [ABSTRACT FROM AUTHOR]

Two kinds of 4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene (BODIPY) dyads BDP‐OH containing 4‐hydroxystyrene groups and BDP‐PY bearing pyridinyl units were prepared. In addition, a naphthalene derivative NAP‐PY modified by pyridinyl moieties substituent was made. The above three dyads could be used to construct white‐light emission (WLE) material by a supramolecular engineering strategy due to their three primary colors of blue, green and red. The supramolecular correlations between the hydroxyl group of BDP‐OH and the pyridinyl groups of NAP‐PY and BDP‐PY were confirmed by 1H NMR titration, 2D NOESY and FTIR. A fluorescence monitor application was carried out based on the realization of WLE. This work might be useful for designing other WLE supramolecular systems and image display. [ABSTRACT FROM AUTHOR]

Abstract Ethnopharmacological relevance Zuotai (gTso thal) has a long history in the treatment of cardiovascular disease, liver and bile diseases, spleen and stomach diseases as a precious adjuvant in Tibetan medicine. However, Zuotai is a mercury preparation that contains 54.5% HgS. Its application has always been controversial. Aim of the study To evaluate the toxicological effects of Zuotai in hepatocytes and in zebrafish. Materials and methods MTT was used to determine the survival rate of hepatocytes; Hoechst and TUNEL staining were used to detect the apoptosis cells; Western blot and RT-qPCR assay were used to determine the expression levels of the protein and mRNA; Liver morphology observation and H&E staining were used to evaluate the hepatotoxicity of Zuotai in Zebfrafish. Results The survival rate of L-02 cells, HepG2 cells and RBL-2A cells reduced by Zuotai (10−4–0.1 mg/mL) in a dose and time-dependent manner. Zuotai (0.1 mg/mL) induced HepG2 cells shrinkage, condensation and fragmentation and increased the number of apoptosis cells. The protein expression levels of cleaved Caspase-3 and Bax were increased and the expression levels of Bcl-2 were reduced after HepG2 cells exposed to Zuotai (10−4–0.1 mg/mL) for 24 h. In addition, Zuotai (0.2 mg/mL) induced the darker liver color of the larval zebrafish and changed the liver morphologic of adult zebrafish. Zuotai (0.2 mg/mL) also increased the mRNA levels of CYP1A1, CYP1B1 and MT-1 in the liver of adult zebrafish. However, no significantly hepatotoxicity was observed after hepatocytes and zebrafish exposed to HgS at the same dose. Conclusions Results showed that Zuotai induced hepatotoxicity effectively under a certain dose but its hepatotoxicity likely occurs via other mechanisms that did not depend on HgS. Graphical abstract Zuotai, a clinical adjuvant in Tibetan medicine, contains 54.5% HgS, which can induce apoptosis of liver cells and liver injury in zebrafish. However, HgS, the principal component of Zuotai did not exhibit hepatotoxicity at the same dose. fx1 [ABSTRACT FROM AUTHOR]

The aggregate morphologies of 4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene (BODIPY) main chain supramolecular polymer amphiphiles (SPA) are tunable by a fine balance of different non‐covalent interactions. When the BODIPY segments and sodium cholate are mixed in aqueous solution, they form SPA by electrostatic attraction and hydrogen‐bonds. This SPA displays helical nanowires' morphology. After the third component dimeric β‐cyclodextrin (β‐CD‐C) is added, the hydrogen bonds between the cholate are substituted by the host–guest interaction between cholate and β‐CD‐C. Therefore, these SPA transform their aggregate morphologies into nanosheets' architecture. Therefore, a simple and effective way to regulate self‐assembly by non‐covalent forces is developed. This supramolecular method may provide an effective way to prepare various nanostructures in aqueous solution and show promising application in the future. [ABSTRACT FROM AUTHOR]

The azide anion as an energy acceptor and an electron donor has been introduced into a metal–viologen compound to form a 2D layered viologen-based trifunctional material, which exhibits the rare discolored function of reversible photochromism and thermochromism. Interestingly, its fluorescence can be switched by visible light irradiation and heating in air. [ABSTRACT FROM AUTHOR]

[Display omitted] Oral colon targeted drug delivery system (OCTDDS) is desirable for the treatment of ulcerative colitis (UC). In this study, we designed a partially oxidized sodium alginate-chitosan crosslinked microsphere for UC treatment. Dissipative particle dynamics (DPD) was used to study the formation and enzyme response of gel beads from a molecular perspective. The formed gel beads have a narrow particle size distribution, a compact structure, low cytotoxicity and great colon targeting in vitro and in vivo. Animal experiments demonstrated that gel beads promoted colonic epithelial barrier integrity, decreased the level of pro-inflammatory factors, accelerated the recovery of intestinal microbial homeostasis in UC rats and restored the intestinal metabolic disorders. In conclusion, our gel bead is a promising approach for the treatment of UC and significant for the researches on the pathogenesis and treatment mechanism of UC. [ABSTRACT FROM AUTHOR]