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Aim: Advances in the techniques and materials used in hypospadias surgery are aimed at improving cosmetic and functional results. In our study, we aimed to compare the impact of using Zaontz urethral stent (ZUS) on patient comfort in children undergoing hypospadias surgery, as opposed to feeding tubes. Materials and Methods: A total of 178 patients who underwent distal hypospadias surgery were included in the study. Snodgrass technique was performed routinely in all cases. In all cases, 6 Fr, 8 Fr and 10 Fr urethral stents were used depending on the surgical situation. Patients were divided into two groups according to the catheterization method. While in Group 1, catheterization was performed with a feeding tube, ZUS was used in Group 2. Demographic data of the patients were analyzed. In the postoperative period, the groups were compared in terms of patient comfort according to the Parents' Postoperative Pain Measurement (PPPM) scale. This scale was evaluated three times a day during the hospitalization period. A score of at least 6 out of 15 was considered clinically significant pain. Results: Age, catheterization size, operation and hospitalization time were similar between the groups (p>0.05). PPPM score in Group 2 was observed as 3.25, significantly lower than Group 1 (p<0.001). Conclusion: As a result of our study, it was observed that ZUS would positively contribute to postoperative patient comfort in hypospadias repair. [ABSTRACT FROM AUTHOR]

Objective: Predisposing factors of Peyronie’s disease remain controversial. We know that obesity has extremely negative effects on erectile tissue. Therefore, in our study, we aimed to examine the relationship between Peyronie’s disease and the body shape index (ABSI), which is a new parameter for the evaluation of visceral adiposity. Materials and Methods: In this study, 55 healthy volunteers (group-1) and 50 Peyronie’s disease patients (group-2). Age, comorbidities, waist circumference (WC), height, body mass index (BMI), testosterone, fasting glucose, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, International Index of Erectile Function (IIEF), and ABSI scores of all patients were analyzed. In addition, plaque sizes, duration of symptoms, and curvature degrees of patients in group 2 were calculated. Results: The mean ages of group 1 and group 2 were 57.02±8.34 years and 56.02±10.65 years, respectively (p>0.05). Fasting glucose, WC, BMI, and ABSI values were significantly higher in group 2 (p=0.031, p<0.001, p=0.026 and p<0.001). LDL and HDLvalues were similar between both groups (p>0.05). The IIEF score was observed to be lower in group 2 (p<0.001). In terms of ABSI values, the discrimination power of Peyronie’s disease was strong. The cut-off value for the ABSI score was 0.08. For this cut-off point, classification success was determined as 88.0% sensitivity and 80.0% selectivity. Conclusion: ABSI can be a reliable independent risk factor for Peyronie’s disease and a predictor of visceral adiposity. [ABSTRACT FROM AUTHOR]

This study aims to evaluate the protective efficacy of remifentanil against testicular ischemia-reperfusion injury.The study included 24 male rats. The rats were randomized into three groups: Group 1 was the control group. Group 2 was subjected to a testicular torsion/detorsion model. Group 3 underwent similar procedures and additionally received remifentanil (0.6 μg/kg/min) intravenously for the first 20 min of reperfusion. Blood samples were taken for biochemical analyses, and orchiectomy was performed for histopathologic examination.Biochemical analysis of blood samples showed a significant increase in antioxidant enzyme activity, including superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in Group 3 compared to Group 2 (p:0.004 and p:0.002, respectively). There was a dramatic decrease in the levels of proinflammatory cytokines, including interleukin-1 beta (IL-1 Beta), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) in Group 3 compared to Group 2 (p:0.001, p:0.046, and p:0.004, respectively). Similarly, malondialdehyde (MDA) levels decreased in Group 3 compared to Group 2 (p:0.004). Histopathologic examination of Group 3 rats showed positive changes in inflammation, hemorrhage, edema, and congestion levels compared to Group 2 (p<0.001). Similarly, there was a positive effect on the Johnsen and Cosentino score in Group 3 compared to Group 2 (p:0.001 and p<0.001, respectively).In our study, it has been documented that remifentanil protects against testicular ischemia-reperfusion injury. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to evaluate the sexual function in patients who underwent a transrectal ultrasonography-guided prostate needle biopsy (TRUS-Bx) using 16G and 18G needles. Materials and Methods: Ninety patients underwent TRUS-Bx. Group 1 included patients who underwent biopsy with an 18G needle (n=45), and group 2 included patients who underwent biopsy with a 16G needle (n=45). Sexual function in both groups was prospectively compared. Additionally, the patients' age, prostatespecific antigen (PSA), prostate volume, cancer detection rate, complication rates, visual analog scale (VAS), and International Index of Erectile Function (IIEF) scores were compared. Results: Age, PSA, prostate volume, cancer detection rate, complication rates and VAS were not found statistically different between the groups. No difference was observed between the two groups in terms of the five main items of IIEF before the procedure. The intercourse satisfaction value was found to be significantly lower after the procedure than before the procedure in group 1 (p<0.05). Orgasmic function, intercourse satisfaction, and overall satisfaction were statistically significantly lower after the procedure than before the procedure in group 2 (p<0.001). Orgasmic function and overall satisfaction were lower in group 2 and significantly different between the two groups four weeks after the procedure (p<0.001). Conclusion: Although erectile function, sexual desire, and intercourse satisfaction were not different on using different needle sizes, in patients where 16G needles were used, orgasmic function and overall satisfaction were lower four weeks after the procedure. [ABSTRACT FROM AUTHOR]