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The article presents the discussion on the extinction of Cherokee, an Indigenous language around the world with just two thousand fluent speakers including indigenous data collection, curation, and sovereignty in partnership with anthropologists.

The article discusses how humanities centers across the U.S. have risen to the challenge resulted due to opioid crisis. It discusses the increasing number of deaths related to heroin in the U.S. roughly one in nine took place in the state, even though it has less than five percent of the U.S. population.

An introduction is presented in which the editor discusses various topics within the issue including disability studies, sense of common vulnerability and responsibility, and medical humanities.

An editorial is presented which discusses the Data Refuge that is a collaboration between librarians, scientists and humanists to save climate archives that are at risk on federal Web sites. It states that a Data Refuge event was held before the inauguration of President Donald Trump, featuring 150 librarians, Web archivists and humanists at the Van Pelt Library in Schlanger and that since then, over fifty other similar events have been organized across North America.

The article offers information on the Kelly Writers House, school of Pennsylvania, that was launched in January 2017. It offers information on Julia Bloch, director of creative writing at the University of Pennsylvania. It mentions that the school was developed by the Philadelphia architect Samuel Sloan. It offers information on Wharton School.

In this article, the author talks about the type of work that the periodical reviews and publishes, focusing on the concept of infrastructure art. Topics discussed include the popular art forms in humanities, the contribution of Simon Gikandi, former editor of the periodical, to the periodical's paper review process, and his book "Slavery and the Culture of Taste." Also mentioned is the book "The Human Condition" by Hannah Arendt.

This article explores the growth of world literature due to the social networking web site Facebook. It discusses the use of Facebook to different languages, aside from English as the dominant language. It expects Facebook to shape the structure of world literature. It also addresses the use of the website to promote religious beliefs.

This article discusses the concept of literary genre as world system. It states that traditionally it has been seen as a classifying principle, putting the many subsets of literature under the rule of normative sets. It further states that genre is invoked less as a law, a rigid taxonomic landscape, and more as a self-obsoleting system, a provisional set that will always be bent and pulled and stretched by its many subsets and such bending and pulling and stretching are unavoidable, for what genre is dealing with is a volatile body of material, still developing, still in transit, and always on the verge of taking flight, in some unknown and unpredictable direction. It also discusses family resemblance and kinship and states that family resemblance is multi-location, multi-platform, and multi-dimension. Relatives might resemble one another in broad outlines, in shape and size, they might also resemble one another in some small detail. It also states that a new mathematics which goes by the name "fractal geometry," is used as a scale.

The article presents the reply of Susan Stanford Friedman's discussion of historicism, presentism, and futurism bringing a meditation on linear and nonlinear time.