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AST3-2 (the second Antarctic Survey Telescope) is located in Antarctic Dome A, the loftiest ice dome on the Antarctic Plateau. It produces a huge amount of observational data which require a more efficient data reduction program to be developed. Also the data transmission in Antarctica is much difficult, thus it is necessary to perform data reduction and detect variable and transient sources remotely and automatically in Antarctica, but this attempt is restricted by the unsatisfactory performance of the low power consumption computer in Antarctica. For realizing this purpose, to develop a new method based on the existing image subtraction method and random forest algorithm, taking the AST3-2 2016 dataset as the test sample, becomes an alternative choice. This method performs image subtraction on the dataset, then applies the principle component analysis to extract the features of residual images. Random forest is used as a machine learning classifier, and in the test a recall rate of 97% is resulted for the positive sample. Our work has verified the feasibility and accuracy of this method, and finally found out a batch of candidates for variable stars in the AST3-2 2016 dataset. [ABSTRACT FROM AUTHOR]