1. Physical Functioning, Depression, and Preferences for Treatment at the End of Life: The Johns Hopkins Precursors Study.
- Author
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Straton, Joseph B., Nae-Yuh Wang, Meoni, Lucy A., Ford, Daniel E., Klag, Michael J., Casarett, David, and Gallo, Joseph J.
- Subjects
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MENTAL depression , *DEPRESSION in old age , *MEDICAL care for older people , *GERIATRICS , *DECISION making , *QUALITY of life , *OLDER people - Abstract
To examine the relationship between worsening physical function and depression and preferences for life-sustaining treatment. Mailed survey of older physicians. Longitudinal cohort study of medical students in the graduating classes from 1948 to 1964 at Johns Hopkins University. Physicians who completed the life-sustaining treatment questionnaire in 1998 and provided information about health status in 1992 and 1998 (n=645, 83% of respondents to the 1998 questionnaire; mean age 68). Preferences for life-sustaining treatment, assessed using a checklist questionnaire in response to a standard vignette. Of 645 physicians, 11% experienced clinically significant decline in physical functioning, and 18% experienced worsening depression over the 6-year period. Physicians with clinically significant functional decline were more likely (adjusted odds ratio (AOR)=2.14, 95% confidence interval (CI)=1.18–3.88) to prefer high-burden life-sustaining treatment. Worsening depression substantially modified the association between declining functioning and treatment preferences. Physicians with declining functioning and worsening depression were more likely (AOR=5.33, 95% CI=1.60–17.8) to prefer high-burden treatment than respondents without declining function or worsening depression. This study calls attention to the need for clinical reassessment of preferences for potentially life-sustaining treatment when health has declined to prevent underestimating the preferences of older patients. [ABSTRACT FROM AUTHOR]
- Published
- 2004
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