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Chrysanthemum indicum L. (C. indicum L.), a member of the Compositae family, is a perennial plant that has been used as a traditional medicine for more than 2000 years in China and is widely used for the treatment of Pemphigus, swelling, pain, and scrofula. To date, more than 190 chemical constituents have been isolated and identified from this plant, including flavonoids, terpenoids, phenylpropanoids, and phenolic acids. Numerous modern studies have shown that extracts or monomeric compounds from C. indicum L. have several pharmacological activities, such as anti-inflammatory anti-oxidation, antipathogenic microorganism, anticancer, immune regulation, and hepatoprotective effects. However, resource availability, the research on the mechanism, and quality control are still insufficient, which deserves further efforts. In this paper, the advances in botany, phytochemistry, and pharmacology of C. indicum L were reviewed. We hope that this review can provide important information for traditional Chinese medicine, phytochemistry, synthetic and medicinal chemistry researchers for making full use of C. indicum L. resource. [ABSTRACT FROM AUTHOR]

The authors aimed to investigate female balance or stability control with comparative analysis of the center of pressure trajectory and plantar pressure distribution with different high-heeled shoes while standing on a dynamic surface with multidirectional perturbations. College females with at least 2 years' history of wearing high-heel shoes voluntarily participated in the test with a Novel Pedar insole (Novel, GmBH, Munich, Germany. With heels height increasing, the pressure time integral obviously transfer to the medial forefoot region, with center of pressure trajectory medially deviated significantly, either under anteroposterior or mediolateral perturbations. The passive plantarflexion position of ankle incurred by high heel increased the range of motion in the frontal plane but decreased ankle stability, thus increasing the challenge of body balance maintenance. [ABSTRACT FROM PUBLISHER]