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2 results on '"Shanavas Alikunju"'

1. Testosterone prevents the heat shock-induced overactivation of glycogen synthase kinase-3β but not of cyclin-dependent kinase 5 and c-Jun NH[sub 2]-terminal kinase and concomitantly abolishes hyperphosphorylation of τ Implications for...

Author

Papasozomenos, Sozos C.H. and Shanavas, Alikunju

Subjects
*GLYCOGEN synthesis, *TESTOSTERONE
Abstract

Reports on the prevention of the heat shock-induced overactivation of glycogen synthase kinase-3beta by testosterone and its implications for Alzheimer's disease. Prevention of the heat shock-induced hyperphosphorylation of tau; Initial rate kinase assays; Role of gonadal hormones.

Published
2002
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2. ...kinases in the rat heat shock model: Possible implications for Alzheimer disease.

Author

Shanavas, Alikunju and Papasozomenos, Sozos Ch.

Subjects
*HEAT shock proteins, *PROTEIN kinases
Abstract

Analyzes the activities of different types of protein kinases in forebrain homogenates from female rats after heat shock. Increase activation and inhibition of kinases; Description of a proposed rat heat shock model; Possible role of the protein kinases in the pathogenesis of Alzheimer disease.

Published
2000
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